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1Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors显示文摘The International Committee of Medical Journal Editors (ICMJE) believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016.Darren B Taichman Joyce Backus Christopher Baethge Howard Bauchner Peter W de Leeuw Jeffrey M Drazen John Fletcher Frank Frizelle Irish Groves Abraham Haileamlak Astrid James Christine Laine Larry Peiperl Anja Pinborg Peush Sahni Si-Nan Wu 2016Chinese Medical Journal2016,,2:20
2Nutritional therapy for hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is the most frequent primary liver cancer and presents together with cirrhosis in most cases.In addition to commonly recognized risk factors for HCC development,such as hepatitis B virus/hepatitis C virus infection,age and alcohol/tobacco consumption,there are nutritional risk factors also related to HCC development including high intake of saturated fats derived from red meat,type of cooking(generation of heterocyclic amines)and contamination of foods with aflatoxins.On the contrary,protective nutritional factors include diets rich in fiber,fruits and vegetables,n-3 polyunsaturated fatty acids and coffee.While the patient is being evaluated for staging and treatment of HCC,special attention should be paid to nutritional support,including proper nutritional assessment and therapy by a multidisciplinary team.It must be considered that these patients usually develop HCC on top of long-lasting cirrhosis,and therefore they could present with severe malnutrition.Cirrhosisrelated complications should be properly addressed and considered for nutritional care.In addition to traditional methods,functional testing,phase angle and computed tomography scan derived skeletal muscle index-L3 are among the most useful tools for nutritional assessment.Nutritional therapy should be centered on providing enough energy and protein to manage the increased requirements of both cirrhosis and cancer.Supplementation with branched-chain amino acids is also recommended as it improves response to treatment,nutritional status and survival,and finally physical exercise must be encouraged and adapted to individual needs.Astrid Ruiz-Margáin Berenice M Román-Calleja Paulina Moreno-Guillén JoséA González-Regueiro DeyaniraKúsulas-Delint Alejandro Campos-Murguía Nayelli C Flores-García Ricardo Ulises Macías-Rodríguez 2021World Journal of Gastrointestinal Oncology2021,13,10:4
3Toxoplasma gondii : from animals to humans显示文摘Astrid M Tenter Anja R Heckeroth Louis M Weiss 2000International Journal for Parasitology2000,,12:4
4临床试验数据共享声明国际医学期刊编辑委员会统一要求显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了1项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。迄今,应我们的反馈要求,ICMJE收到了很多来自个人和团体的意见。Darren B Taichman Peush Sahni Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Deutsches Arzteblatt Joyce Backus 季媛媛 2017英国医学杂志中文版2017,20,7:2
5临床试验数据共享声明显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了一项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。Darren B Taichman Peush Sahni Anja Pinborg Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Joyce Backus 季媛媛 2017中国医院院长2017,13,16:2
6Micro RNA-29,a key regulator of collagen expression in systemic sclerosis显示文摘Britta M Joanna S Astrid J 2010Arthritis&Rheumatism2010,62,6:1
7Extent of thrombus evaluated in patients with recurrent and first deep vein thromb6sisJ显示文摘Astrid M Fink MD 2002J Vasc Surg2002,36,18:1
8Patterning the embryonic heart: Identification of five mouse iroquois homeobox genes in the developing heart显示文摘 KEIJSER Astrid G M ARJAN C 2000Dev Biol2000,224,:1
9A new lysozyme fold: crystal structure of the muramidase from Streptomyces coelicolor at 1,65 A resolution显示文摘Astrid R Tanis H Rudiger M 2001J Biol Chem2001,276,31:1
10Production of cellulases and hemicellulases by three Penicillium species:effect of substrate and evaluation of cellulase adsorption by capillary electrophoresis显示文摘Henning J Astrid M Kristian B R 2005Enzyme and Microbial Technology2005,36,:1
11Extent of thrombus evaluated in patients with recurrent and first deep vein thrombosis显示文摘Astrid M Fink MD 2002J Vase Surg2002,36,18:1
12Production of cellulases and hemicellulases by three Penicillium species : Effect of substrate and evaluation of cellulase adsorption by capillary electrophoresis 显示文摘HENNING J ASTRID M KRISTIAN B R 2005Enzyme and Microbial Technology2005,36,:1
13Natural diversity of potato (Solarium tuberos urn) invertases 显示文摘Astrid M D Sebastian M Li I 2010Plant Biology2010,10,:1
14Pattering the embryonic heart : Identification of five mouse iroquois homeobox genes in the developing heart显示文摘 KEIJSER Astrid G M HIUWELING Arjan C 2000Dev Bio2000,224,:1
15Extent of thrombus evaluated in patients with recurrent and first deep vein thrombosis显示文摘 Fink MD 2002J Vasc Surg2002,36,18:1
16Extent of thrombus evaluated in patients with recurrent and first deep vein thrombosis显示文摘Astrid M Fink MD 2002J Vase surg2002,36,18:1
17Multiplex rea1-time NASBA for monitoring expression dynamics of human cytomegalovirus encoded IEI and pp67 RNA显示文摘Astrid E Henrietta M A Adriaanse E et a1 2002Clin Virol2002,24,1:1
18Clinical significance of pulmonary nodules detected by CT and Not CXR in patients treated for favorable histology Wilms tumor on national Wilms tumor studies-4 and -5:A report from the Children's Oncology Group显示文摘Paul E Daniel M Astrid C 2012Pediatr Blood Cancer2012,59,:1
19SCA2 trinucleotide expansion in German SCA patients显示文摘Olaf Riess Franco A. Laccone Suzana Gispert Ludger Sch?ls Christine Zühlke Ana Maria Menezes Vieira-Saecker Susanne Herlt Karl Wessel J?rg T. Epplen Bernhard H.F. Weber Friedmar Kreuz Soheyla Chahrokh-Zadeh Alfons Meindl Astrid Lunkes Jorge Aguiar Milan M 1997Neurogenetics1997,,1:1
20The pronostic signifisance of proliferition cell nuclear antigen, Epidermal growth Factor Recepter and mdr gene expresesion in coloretal cancer显示文摘 Masafumi T Elke F 1993Cancer1993,71,69:1
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