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| 1 | Low-volume plus ascorbic acid vs high-volume plus simethicone bowel preparation before colonoscopy显示文摘AIM:To investigate the effectiveness of low-volumeplus ascorbic acid [polyethylene glycol plus ascorbicacid(PEG + Asc) ] and high-volume plus simethicone[polyethylene glycol plus simethicone(PEG + Sim) ]bowel preparations.METHODS:A total of one hundred and forty-fourout patients(76 males) ,aged from 20 to 84 years(me-dian age 59.5 years) ,who attended our Department,were divided into two groups,age and sex matched,and underwent colonoscopy. Two questionnaires,onefor patients reporting acceptability and the other forendoscopists evaluating bowel cleansing effectivenes saccording to validated scales,were completed. Indications,timing of examination and endoscopical findings were recorded. Biopsy forceps were used as a measuring tool in order to determine polyp endoscopic sizeestimation. Difficulty in completing the preparation wasrated in a 5-point Likert scale(1 = easy to 5 = un-able) . Adverse experiences(fullness,cramps,nausea,vomiting,ab dominal pain,headache and insomnia) ,number of evacuations and types of activities performed during preparation(walking or resting in bed) were also investigated.RESULTS:Seventy-two patients were selected for eachgroup. The two groups were age and sex matched aswell as being comparable in terms of medical historyand drug therapies taken. Fourteen patients droppedout from the trial because they did not complete the preparation procedure. Ratings of global bowel cleansing examinations were considered to be adequate in91% of PEG + Asc and 88% of PEG + Sim patients.Residual Stool Score indicated similar levels of amountand consistency of residual stool;there was a significant difference in the percentage of bowel wall visuali-zation in favour of PEG + Sim patients. In the PEG +Sim group,12 adenomas ≤ 10 mm diameter(5/left co-lon + 7/right colon) vs 9(8/left colon + 1/right colon) in the PEG + Asc group were diagnosed. Visualization of small lesions seems to be one of the primary advantages of the PEG + Sim preparation.CONCLUSION:PEG + Asc is a good alternative solution as a bowel preparation but more improvements arenecessary in order to achieve the target of a perfect preparation. | Stefano Pontone Rita Angelini Monica Standoli Gregorio Patrizi Franco Culasso Paolo Pontone Adriano Redler | 2011 | World Journal of Gastroenterology2011，17，42： | 22 |
| 2 | Liver metastases:Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance显示文摘The development of ultrasound contrast agents with excellent tolerance and safety profiles has notably improved liver evaluation with ultrasound(US)for several applications,especially for the detection of metastases.In particular,contrast enhanced ultrasonography(CEUS)allows the display of the parenchymal microvasculature,enabling the study and visualization of the enhancement patterns of liver lesions in real time and in a continuous manner in all vascular phases,which is similar to contrast-enhanced computed tomography(CT)and contrast-enhanced magnetic resonance imaging.Clinical studies have reported that the use of a contrast agent enables the visualization of more metastases with significantly improved sensitivity and specificity compared to baseline-US.Furthermore,studies have shown that CEUS yields sensitivities comparable to CT.In this review,we describe the state of the art of CEUS for detecting colorectal liver metastases,the imaging features,the literature reports of metastases in CEUS as well as its technique,its clinical role and its potential applications.Additionally,the updated international consensus panel guidelines are reported in this review with the inherent limitations of this technique and best practice experiences. | Vito Cantisani Hektor Grazhdani Cristina Fioravanti Maria Rosignuolo Fabrizio Calliada Daniela Messineo Maria Giulia Bernieri Adriano Redler Carlo Catalano Ferdinando D’Ambrosio | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 3 | Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors’ experience显示文摘 | Claudio Renzi Castellani Francesco Barberini Roberto Cirocchi Gemini Noya Boselli Parisi Corsi Desiderio Adriano Redler Trastulli Alberto Santoro | 2013 | 2013 (defa)2013，，： | 2 |
| 4 | Requirement for a standardised definition of advanced gastric cancer显示文摘 | Angelo De Sol Stefano Trastulli Veronica Grassi Alessia Corsi Ivan Barillaro Andrea Boccolini Micol Di Patrizi Giorgio Di Rocco Alberto Santoro Roberto Cirocchi Carlo Boselli Adriano Redler Giuseppe Noya Seong-Ho Kong | 2014 | Oncology Letters2014，，1： | 1 |
| 5 | Pneumatic balloon dilation in pediatric achalasia: efficacy and factors predicting outcome at a single tertiary pediatric gastroenterology center显示文摘 | Giovanni Di Nardo Paolo Rossi Salvatore Oliva Marina Aloi Denis A. Cozzi Simone Frediani Adriano Redler Saverio Mallardo Federica Ferrari Salvatore Cucchiara | 2012 | Gastrointestinal Endoscopy2012，，5： | 1 |
| 6 | Long-term multiple intragastric balloon treatment—a new strategy to treat morbid obese patients refusing surgery: prospective 6-year follow-up study显示文摘 | Genco Alfredo Maselli Roberta Cipriano Massimiliano Lorenzo Michele Basso Nicola Redler Adriano | 2013 | Surgery for Obesity and Related Diseases2013，，： | 1 |
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