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    题名 作者 年代 出处 被引量
1α-1-Syntrophin Mutation and the Long-QT Syndrome: A Disease of Sodium Channel Disruption显示文摘Geru Wu Tomohiko Ai Jeffrey J. Kim Bhagyalaxmi Mohapatra Yutao Xi Zhaohui Li Shahrzad Abbasi Enkhsaikhan Purevjav Kaveh Samani Michael J. Ackerman Ming Qi Arthur J. Moss Wataru Shimizu Jeffrey A. Towbin Jie Cheng Matteo Vatta 2008Circulation: Arrhythmia and Electrophysiology2008,,3:1
2Preparation and characteristics of chitosan microspheres in different acetylation as drug carrier system显示文摘Ai Hong Wang Xi Guang Chen Cheng Sheng Liu Xiang Hong Meng Le Jun Yu Hua Wang 2009Journal of Microencapsulation2009,,7:1
3Polar enhancement of the Nonlinear Optical Properties of Fe2O3microcrystallites显示文摘Ai Xi Cheng Fei H Sh Yang Y Q 1994J Luminescence1994,,6:1
4CCGD-ESCC: A Comprehensive Database for Genetic Variants Associated with Esophageal Squamous Cell Carcinoma in Chinese Population显示文摘Esophageal squamous-cell carcinoma(ESCC) is one of the most lethal malignancies in the world and occurs at particularly higher frequency in China. While several genome-wide association studies(GWAS) of germline variants and whole-genome or whole-exome sequencing studies of somatic mutations in ESCC have been published, there is no comprehensive database publically available for this cancer. Here, we developed the Chinese Cancer Genomic Database-Esophageal Squamous Cell Carcinoma(CCGD-ESCC) database, which contains the associations of 69,593 single nucleotide polymorphisms(SNPs) with ESCC risk in 2022 cases and 2039 controls, survival time of 1006 ESCC patients(survival GWAS) and gene expression(expression quantitative trait loci,eQTL) in 94 ESCC patients. Moreover, this database also provides the associations between8833 somatic mutations and survival time in 675 ESCC patients. Our user-friendly database is a resource useful for biologists and oncologists not only in identifying the associations of genetic variants or somatic mutations with the development and progression of ESCC but also in studying the underlying mechanisms for tumorigenesis of the cancer. CCGD-ESCC is freely accessible at http://gffzzdf7d528e3a264cb9hn9fokqx50nxp690c.ffgz.tsg.suse.edu.cn/ccgd/ESCCdb.Linna Peng Sijin Cheng Yuan Lin Qionghua Cui Yingying Luo Jiahui Chu Mingming Shao Wenyi Fan Yamei Chen Ai Lin Yiyi Xi Yanxia Sun Lei Zhang Chao Zhang Wen Tan Ge Gao Chen Wu Dongxin Lin 2018Genomics, Proteomics & Bioinformatics2018,16,4:1
5Aggregate Engineering in Supramolecular Polymers via Extensive Non-covalent Networks显示文摘Aggregate engineering of non-covalent networks endows supramolecular polymers with thermo-mechanical versatility,stimuli-responsive phase transitions and intrinsic damage-healing capabilities.However,most non-covalent networks are vulnerable at elevated temperatures,which suppresses the robustness of supramolecular polymers.Herein,ureidocytosine(UCy)motifs,which are capable of forming extensive non-covalent networks and thus robust molecular aggregates via multivalent hydrogen bonds and aromatic stackings,are proposed to enable precise programming of the thermo-mechanical versatility.Molecular simulations reveal that the enthalpic contributions from the UCy aggregates play dominant roles to compensate the entropic loss from the redistributions of polymeric spacers and stabilize the non-covalent networks over wide temperature windows.Such aggregate-level strategy offers prospects for applications which require thermo-mechanical versatility of supramolecular polymers,such as 3D printing,microfabrication and damage-healing coating.Xin Huang Dong Lv Li-Qing Ai Shuk Han Cheng Xi Yao 2021Chinese Journal of Polymer Science2021,39,10:0
6The Energy Transfer Processes between Carotenoid and Chlorophyll Regulated by Electron Exchange Mechanism显示文摘The energy transfer efficiency between carotenoids and chlorophyll depend on temperature and viscosity of the media. A 3.5 ps process was detected by the pico-second time-resolved spectra and the process was proved to be regulated by electron exchange mechanism.Ye LI Jing Quan ZHAO Li Jin JIANG Zhao Yong SUN Xi Cheng AI Xing Kang ZHANG 2001Chinese Chemical Letters2001,12,11:0
7Characterization of Highly Pathogenic Avian Influenza H5N1 Viruses Isolated from Domestic Poultry in China显示文摘高度病原的鸟的流行性感冒(HPAI ) H5N1 病毒在国内家禽引起了几爆发。尽管有控制这个病毒的传播的大努力,它继续演变并且因为高死亡率,形成实质的威胁到公共健康。在这研究,我们定序在东方中国从国内家禽孤立并且典型流行性感冒病毒紧张把他们与那些作比较的八个 H5N1 鸟的流行性感冒病毒的整个染色体。种系发生的分析证明所有八个染色体属于 clade 2.3.2.1 并且 clade 7.2,在中国的二主要传播 clades。那在 2.3.2.1 分享了的 clade 聚类的病毒有 H5N1 的相同的高度孤立在东方亚洲人定位了。孤立在 7.2 被发现在整个中国传播的 clade 聚类那,与一个 east-to-west 密度坡度。在老鼠的致病力研究显示出那这些孤立在肺,和 clade 复制 2.3.2.1 病毒展览与 clade 相比的毒力的尤其是更高的度 7.2 个病毒。我们的结果贡献 HPAI H5N1 病毒的生物描述和致病力的说明。LAI Cheng Cai WANG Ke Yu CHEN Rui ZHANG Ai Jun GU Hong Jing YIN Yan Bo WANG Dong Dong LIU Lin Lin XING Li TONG Yi Gang MA Zong Juan YANG Peng Hui WANG Xi Liang 2017Biomedical and Environmental Sciences2017,30,1:0
8Research on PbS Nanoparticles Coated with 2,6-O-Diallyl-β-CD显示文摘PbS nanoparticles coated with 2.6-O-dial1yl-β-CD were prepared successfully and characterized by transmission electron microscope (TEM), X-ray photoelectron spectrometer (XPS). The sample shows a very rapid inducedYun LING Lin GUO Liang ZHANG Xi Cheng AI Ruo Nong FU Qian Shu LI He Sun ZHU (College of Chemical Engineering and Materials Science, Beijing Institute of Technology, Beijing 100081) (Correspond author) 1997Chinese Chemical Letters1997,8,3:0
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