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| 1 | Classification and regionalization of the forming environment of windblown sand disasters along the Tarim Desert Highway显示文摘Through the systematic field survey and observations, the factor quantification as well as setting the criteria, the sand disaster-forming environment along the Tarim Desert Highway can be divided into four grades by the classification and regionalization based on fuzzy mathematics. The length of the regions with significant sand disaster accounted for 37.1% of the total highway length. Particularly, the area along the Tarim Desert Highway, based on the sand disaster-forming environment classification as well as the difference in the five basic landform units along the highway, combined with the difference of wind regime, can be divided into five regions, in which the length of the regions suffering severe sand damage occupied 64.3% of the total highway length. In addition, the index of disaster formation grade along the highway decreased from north to south, showing a repeated spatial pattern in small length scales. | LEI JiaQiang LI ShengYu FAN DongDong ZHOU HongWei GU Feng QIU YongZhi XU Bo LIU Shang DU WenYi YAN ZengHui WANG YongChang | 2008 | Chinese Science Bulletin2008，53，S2： | 11 |
| 2 | Effect of terrain on landscape patterns and ecological effects by a gradient-based RS and GIS analysis显示文摘Terrain is an important environment factor that plays a vital role in human development by influencing the spatial layout of land use patterns.The terrain niche index,combined with slope and elevation,can comprehensively present detailed information about spatial differences in terrain and is superior to single terrain factors.We applied remote sensing and geographical information system to terrain gradient,used the non-dimensional distribution index to examine spatial distribution characteristics of various landscape types,and analyzed the ecological effects of landscape were quantitatively on terrain gradients.Eco-environment quality(EEQ) was evaluated using the forestry operation area as the evaluation unit.The spatial distributions in various landscapes were significantly influenced by terrain factors,especially by bodies of water,cropland and residential land.The spatial distribution varied greatly in different terrain gradients for similar landscape types.The areas associated with good,intermediate and poor EEQ were occupied primarily by natural landscape,semi-natural and largely artificial landscapes,respectively. | Wenfeng Gong Haibo Wang Xiaofeng Wang Wenyi Fan Philip Stott | 2017 | Journal of Forestry Research2017，28，5： | 5 |
| 3 | Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma显示文摘This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma(ESCC),which if diagnosed at advanced stages has<30%five-year survival rate.Comparing genome-wide methylation sites of 91 ESCC and matched adjacent normal tissues,we identified 35,577 differentially methylated CpG sites(DMCs)and characterized their distribution patterns. | Yiyi Xi Yuan Lin Wenjia Guo Xinyu Wang Hengqiang Zhao Chuanwang Miao Weiling Liu Yachen Liu Tianyuan Liu Yingying Luo Wenyi Fan Ai Lin Yamei Chen Yanxia Sun Yulin Ma Xiangjie Niu Ce Zhong Wen Tan Meng Zhou Jianzhong Su Chen Wu Dongxin Lin | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 2 |
| 4 | Antrodia cinnamomea exerts an anti-hepatoma effect by targeting PI3K/AKT-mediated cell cycle progression in vitro and in vivo显示文摘Antrodia cinnamomea is extensively used as a traditional medicine to prevention and treatment of liver cancer.However,its comprehensive chemical fingerprint is uncertain,and the mechanisms,especially the potential therapeutic target for anti-hepatocellular carcinoma(HCC)are still unclear.Using UPLC-Q-TOF/MS,139 chemical components were identified in A.cinnamomea dropping pills(ACDPs).Based on these chemical components,network pharmacology demonstrated that the targets of active components were significantly enriched in the pathways in cancer,which were closely related with cell proliferation regulation.Next,HCC data was downloaded from Gene Expression Omnibus database(GEO).The Cancer Genome Atlas(TCGA)and Dis Ge NET were analyzed by bioinformatics,and 79 biomarkers were obtained.Furtherly,nine targets of ACDP active components were revealed,and they were significantly enriched in PI3 K/AKT and cell cycle signaling pathways.The affinity between these targets and their corresponding active ingredients was predicted by molecular docking.Finally,in vivo and in vitro experiments showed that ACDPs could reduce the activity of PI3 K/AKT signaling pathway and downregulate the expression of cell cycle-related proteins,contributing to the decreased growth of liver cancer.Altogether,PI3 K/AKT-cell cycle appears as the significant central node in anti-liver cancer of A.Cinnamomea. | Yan Zhang Pin Lv Junmei Ma Ning Chen Huishan Guo Yan Chen Xiaoruo Gan Rong Wang Xuqiang Liu Sufang Fan Bin Cong Wenyi Kang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 5 | Epidemiologic Characteristics of Cases for Influenza A(H7N9) Virus Infections in China显示文摘 | Wenyi Zhang Liya Wang Wenbiao Hu Fan Ding Hailong Sun Shenlong Li Liuyu Huang Chengyi Li | 2013 | Clinical Infectious Diseases2013，，4： | 1 |
| 6 | Epidemiologic features of Severe fever with Thrombocytopenia Syndrome in China, 2011 - 2012 显示文摘 | Fan Ding Wenyi Zhang Liya Wang | 2013 | Clinical Infectious Diseases2013，56，11： | 1 |
| 7 | Spatial heterogeneity and carbon contribution of aboeground biomass of moso bamboo by using geostatistical theory 显示文摘 | DU Huaqiang ZHOU Guomo FAN Wenyi et ol | 2010 | Plant Ecol2010，207，： | 1 |
| 8 | Comparative stud- y between a new nonlinear model and common linear mod- el for analysing laboratory simulated-forest hyperspectral data显示文摘 | FAN Wenyi HU Baoxin Miller J | 2009 | International Journal of Remote Sensing2009，30，11： | 1 |
| 9 | Sptial heterogeneity and carbon contribution of aboveground biomass of moso bamboo by using geostatistical theory显示文摘 | DU Huaqiang ZHOU Guomo FAN Wenyi | | 0，，： | 1 |
| 10 | Spatial heterogeneity and carbon contribution of aboveground biomass of moso bamboo by using geostatistical theory显示文摘 | Huaqiang Du Guomo Zhou Wenyi Fan Hongli Ge Xiaojun Xu Yongjun Shi Weiliang Fan | 2010 | Plant Ecology2010，，1： | 1 |
| 11 | Implanting iodine-125 seeds into rat dorsal root ganglion for neuropathic pain: neuronal microdamage without impacting hind limb motion显示文摘The use of iodine-125(125I) in cancer treatment has been shown to relieve patients' pain. Considering dorsal root ganglia are critical for neural transmission between the peripheral and central nervous systems, we assumed that 125 I could be implanted into rat dorsal root ganglia to provide relief for neuropathic pain. 125 I seeds with different radioactivity(0, 14.8, 29.6 MBq) were implanted separately through L4–5 and L5–6 intervertebral foramen into the vicinity of the L5 dorsal root ganglion. von Frey hair results demonstrated the mechanical pain threshold was elevated after implanting 125 I seeds from the high radioactivity group. Transmission electron microscopy revealed that nuclear membrane shrinkage, nucleolar margination, widespread mitochondrial swelling, partial vacuolization, lysosome increase, and partial endoplasmic reticulum dilation were visible at 1,440 hours in the low radioactivity group and at 336 hours in the high radioactivity group. Abundant nuclear membrane shrinkage, partial fuzzy nuclear membrane and endoplasmic reticulum necrosis were observed at 1,440 hours in the high radioactivity group. No significant difference in combined behavioral scores was detected between preoperation and postoperation in the low and high radioactivity groups. These results suggested that the mechanical pain threshold was elevated after implanting 125 I seeds without influencing motor functions of the hind limb, although cell injury was present. | Ling Jiao Tengda Zhang Huixing Wang Wenyi Zhang Saijun Fan Xiaodong Huo Baosen Zheng Wenting Ma | 2014 | Neural Regeneration Research2014，9，12： | 1 |
| 12 | CCGD-ESCC: A Comprehensive Database for Genetic Variants Associated with Esophageal Squamous Cell Carcinoma in Chinese Population显示文摘Esophageal squamous-cell carcinoma(ESCC) is one of the most lethal malignancies in the world and occurs at particularly higher frequency in China. While several genome-wide association studies(GWAS) of germline variants and whole-genome or whole-exome sequencing studies of somatic mutations in ESCC have been published, there is no comprehensive database publically available for this cancer. Here, we developed the Chinese Cancer Genomic Database-Esophageal Squamous Cell Carcinoma(CCGD-ESCC) database, which contains the associations of 69,593 single nucleotide polymorphisms(SNPs) with ESCC risk in 2022 cases and 2039 controls, survival time of 1006 ESCC patients(survival GWAS) and gene expression(expression quantitative trait loci,eQTL) in 94 ESCC patients. Moreover, this database also provides the associations between8833 somatic mutations and survival time in 675 ESCC patients. Our user-friendly database is a resource useful for biologists and oncologists not only in identifying the associations of genetic variants or somatic mutations with the development and progression of ESCC but also in studying the underlying mechanisms for tumorigenesis of the cancer. CCGD-ESCC is freely accessible at http://gffzzdf7d528e3a264cb9hw9bx5fbnkxck6f5q.ffgz.tsg.suse.edu.cn/ccgd/ESCCdb. | Linna Peng Sijin Cheng Yuan Lin Qionghua Cui Yingying Luo Jiahui Chu Mingming Shao Wenyi Fan Yamei Chen Ai Lin Yiyi Xi Yanxia Sun Lei Zhang Chao Zhang Wen Tan Ge Gao Chen Wu Dongxin Lin | 2018 | Genomics, Proteomics & Bioinformatics2018，16，4： | 1 |
| 13 | Qing Hua Chang Yin exerts therapeutic effects against ulcerative colitisthrough the inhibition of the TLR4/NF?κB pathway显示文摘 | Xiao Ke Fan Zhou Youliang Gao Bingying Xie Guanghong Hu Wenyi Fang Jun Peng Youqin Chen Thomas Sferra | 2013 | International Journal of Molecular Medicine2013，，4： | 1 |
| 14 | Spatial heterogeneity and carbon contribution of aboveground biomass of moso bamboo by using geostatistical theory 显示文摘 | Du Huaqiang Zhou Guomo Fan Wenyi | 2010 | Plant Ecology2010，207，1： | 1 |
| 15 | Spatial heterogeneity and carbon contribution of aboveground biomass of moso bamboo by using geostatistical theory显示文摘 | DU Huaqiang ZHOU Guomo FAN Wenyi | 2010 | Plant Ecology2010，207，1： | 1 |
| 16 | High-density fiber optic array technology and its applica- tions in functional genomic studies显示文摘 | Jianbing Fan Diping Che Chanfeng Zhao Lixin Zhou Wenyi Feng | 2003 | Chinese Science Bulletin2003，48，18： | 0 |
| 17 | A Novel 360°3D Profilometry显示文摘ANovel360°3DProfilometry①SONGYuanhe,ZHAOHong,FANHua,CHENWenyi,TANYushan(ResearchInstituteforLaser&InfraredApplications,Xi’anJ... | SONG Yuanhe,ZHAO Hong,FAN Hua,CHEN Wenyi,TAN Yushan (Research Institute for Laser & Infrared Applications, Xi’an Jiaotong University,Xi’an 710049,CHN) | 1998 | Semiconductor Photonics and Technology1998，4，1： | 0 |
| 18 | Monitoring Forest Growth Disturbance Using Time Series MODIS EVI Data显示文摘Forest growth is mainly currently monitored using in-situ measurements in northeast of China.To effectively monitor forest growth disturbance at large scale,we attempted to use remote sensing technique,particularly,time series MODIS data from 2004 to 2006.The annual time series of 8-day enhanced vegetation index(EVI) dataset was generated and smoothed using a Savitzky-Golay filter.The EVI trajectory during growth season was simulated using a logistic model. From the simulated trajectory,the EVI area of growth season and annual EVI entropy were calculated.These two factors were combined to map the disturbance regions of forest growth. Finally,the disturbance regions were verified using a set of random samples.The result indicates that the disturbance points have distinctively higher entropy and lower peak.Some of these points also show abrupt EVI decline during the midseason of the peak phases or double peaks.This approach is demonstrated to be feasible for disturbance monitoring of forest growth. | Liu Lijuan Pang Yong Zhang Xiaoyang Svein Solberg Fan Wenyi Li Zengyuan Li Mingze | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 19 | Effect of Tremella fuciformis polysaccharide on the stalling and flavor of tteok during storage显示文摘The effect of Tremella fuciformis polysaccharide(TFP)on the retrogradation property and aroma profile changes of tteok during storage was investigated.Results indicated that addition of TFP significantly increased the stability to thermal and mechanical shearing of starch,decreased short-term retrogradation,the hardness and the retrogradation enthalpy(ΔH)of tteok during storage,but had no significant effect on the amylopectin chain length of tteok.The possible mechanism for the retarding staling effect of TFP is related to the interaction between TFP and starch chains that interferes with the alignment of starch chains.Electronic nose and g as chromatography-mass spectrum(GC-MS)analysis results showed that the difference in the concentrations of volatile compounds and fatty acids of tteoks at different storage time gradually increased with the advancement of storage period.The addition of TFP to tteok inhibited the development of unpleasant volatile compounds,probably by delaying the oxidation and decomposition of lipids and preserving the antioxidant phenolic compounds in tteok,thus slowing down the flavor deterioration of tteok and contributing to flavor maintainace.Overall,this study could help food manufacturers to choose a high-effective and natural polysaccharide to control the retrogradation rate and flavor loss of tteok. | Hongxiu Fan Hongcheng Liu Wenyi Li Wenjing Su Dawei Wang Shanshan Zhang Tingting Liu Yanrong Zhang | 2023 | Food Science and Human Wellness2023，12，1： | 0 |
| 20 | Management and operation of extra-large Fangcang hospitals:experience and lessons from containing the highly contagious SARS-CoV-2 Omicron in Shanghai,China显示文摘Introduction Omicron is more contagious and stealthier than the previous strains.The basic reproduction number of Omicron is around 8–12,whereas that of the previous mainstream strain Delta is only 5–8[1].Omicron’s symptoms are relatively mild[2]compared with Delta’s symptoms;however,Omicron’s transmission ability is very strong,and its risk to children and the elderly remains high[3].In addition,the vaccine’s preventive effect on Omicron has weakened.Therefore,Omicron can easily cause a rapid outbreak in a city.The population density of megacities and the limited public health resources further exacerbate the difficulty of Omicron prevention and control. | Yun Xian Chenhao Yu Minjie Chen Lin Zhang Xinyi Zheng Shijian Li Erzhen Chen Zhongwan Chen Weihua Chen Chaoying Wang Qingrong Xu Tao Han Weidong Ye Wenyi Xu Xu Zhuang Yu Zheng Min Chen Jun Qin Yu Feng Shun Wei Yiling Fan Zhiruo Zhang Junhua Zheng | 2023 | Frontiers of Medicine2023，17，1： | 0 |
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