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26篇 您的检索式:作者名="Akshaya"
    题名 作者 年代 出处 被引量
1Optical studies of Eu3+ ions doped in tellurite glass显示文摘Akshaya Kuma Rai D K 2002Spectrochimica Acta Part A2002,58,:2
2Treatment outcomes of visceral leishmaniasis in Ethiopia from 2001 to 2017:a systematic review and meta-analysis显示文摘Background:Ethiopia has the highest number of visceral leishmaniasis(VL)cases after Sudan in Sub-Saharan Africa.However,there was lack of comprehensive data on VL treatment outcome despite the huge burden of the diseases in the country.Hence,we aimed to perform a systematic review and meta-analysis on this topic to obtain stronger evidence on treatment outcomes of VL from the existing literature in Ethiopia.Methods:The Cochrane guidelines to conduct meta-analysis following the Preferred Reporting Items for Systematic review and Meta-Analysis statement was used to conduct a computerized systematic search of the PubMed,Google Scholar,and ScienceDirect databases.Random effects model was used to combine studies showing heterogeneity of Cochrane Q P<0.10 and I2>50.Treatment outcomes were assessed at end of treatment and at 6 months follow-up.Subgroup analyses were performed on treatment outcomes based on the different antileishmanial treatment options and patients’HIV status.Results:Fifteen studies were included in the final analyses.At end of treatment,an overall treatment success rate of 82.6%was noticed.At 6 months follow-up,the overall treatment success rate was 72.2%.For patients treated with sodium stibogluconate(SSG),the treatment success rates at the end of treatment and at six-month follow-up were 81.5%and 80.7%,respectively.Multiple doses of liposomal-amphotericin B(L-AMB)had treatment success rates of 96.7 and 71-100%at the end of treatment and at 6 months follow-up,respectively.The combination of SSG with paromomycin(PM)gave treatment success rates of up to 90.1%at the end of treatment.HIV-infected individuals were found to have a higher mortality(odds ratio=4.77,95%CI:1.30-17.43,P=0.009)rate at 6 months follow-up.Conclusions:SSG alone has shown lower treatment efficacy in the management of VL when compared to combination of SSG with PM and multiple doses of L-AMB.The combination of SSG with PM gave good treatment success rates with shorter duration of treatment.Hence,the combination of SSG with PM should be used preferentially over SSG monotherapy.Multiple doses of L-AMB showed great efficacy especially among patients with complications,severe disease,HIV co-infection,and intolerance to the adverse effects of antimonials.HIVinfected individuals had a worse prognosis than their HIV-negative counterparts.Eyob Alemayehu Gebreyohannes Akshaya Srikanth Bhagvathula Tadesse Melaku Abegaz Mohammed Assen Seid 2018Infectious Diseases of Poverty2018,7,1:1
3Optical studies of Eu^3+ i- ons doped in tellurite glass显示文摘AKSHAYA K RAID K RA1 S B 2002Spectrochimica Acta Part A2002,,58:1
4A review on chemical coagulation/flocculation technologies for removal of colour from textile wastewaters显示文摘Akshaya Kumar Verma Rajesh Roshan Dash Puspendu Bhunia 2011Journal of Environmental Management2011,,1:1
5Input-output linearization and robust sliding-mode controller for the VSC-HVDC transmission link显示文摘Akshaya Moharana Dash P K 2010IEEE Transac- tion on Power Delivery2010,25,3:1
6New low temperature electrolytes with thermal runaway inhibition for lithium-ion rechargeable batteries 显示文摘BRAJA K M AKSHAYA K P ZHONG S 2006Journal of Power Sources2006,161,:1
7Input-output lineari- zation and robust sliding-mode controller for the VSC-HVDC transmission link显示文摘Akshaya Moharana P K Dash 2010IEEE Transactions on Power Delivery2010,25,3:1
8Miniaturized on-sensor fluorescence flow cytometer显示文摘Akshaya S Christopher DS 2012Sensors IEEE2012,,:1
9Optics Express 显示文摘Akshaya Mishra Alexandcr Wong Kostadinka Bizheva 200917 ( 26 ) : 23719 - 237282009,17,23:1
10Prevalence of potential drug–drug interactions among internal medicine ward in University of Gondar Teaching Hospital, Ethiopia显示文摘Akshaya Srikanth Bhagavathula Alemayehu Berhanie Habtamu Tigistu Yishak Abraham Yosheph Getachew Tahir Mehmood Khan Chandrashekhar Unakal 2014Asian Pacific Journal of Tropical Biomedicine2014,,:1
11用流动孔隙测量术设计复合型过滤介质显示文摘为使过滤材料在使用中达到令人满意的性能 ,要求过滤介质具有适宜的孔径尺寸、孔径分布、孔体积、孔表面积及渗透性。在本项调研中 ,将过滤介质用流动孔隙测量术进行了特征化处理 ,然后用预先特征化处理过的过滤介质设计复合型过滤介质 ,并用流动孔隙测量术测试复合型过滤介质。测量并分析通过干样品和湿样品的气体压力和流量 ,由此得出最大孔径尺寸、孔径分布及渗透性。数据表明 ,具有独特特征的复合型过滤介质可以通过合理挑选预先特征化处理过的过滤介质来制备。Akshaya Jena Krishna Gupta 王向农 2001产业用纺织品2001,19,3:1
12Double-pulse laser-induced breakdown spectroscopy with liquid lets of different thicknesses 显示文摘K Akshaya Y Y Fang P S Jagdish 2003Appl Opt2003,42,30:1
13Possible role of laccase from Fusarium incarnatum UC 14in bioremediation of Bisphenol A using reverse miceUes system 显示文摘Urvish C Akshaya G 2013Journal of Hazardous Materials2013,,:1
14Character- ization of suspended sediment in meltwater from glaciers of Garhwal Himalaya显示文摘Deepak Srivastava Amit Kumar Akshaya Verma eta! 2014Hydrological Processes2014,28,3:1
15Alternatives to currently used antimalarial drugs: in search of a magic bullet显示文摘Malaria is a major cause of morbidity and mortality in many African countries and parts of Asia and South America.Novel approaches to combating the disease have emerged in recent years and several drug candidates are now being tested clinically.However,it is long before these novel drugs can hit the market,especially due to a scarcity of safety and efficacy data.To reduce the malaria burden,the Medicines for Malaria Venture(MMV)was established in 1999 to develop novel medicines through industry and academic partners’collaboration.However,no reviews were focused following various preclinical and clinical studies published since the MMV initiation(2000)to till date.We identify promising approaches in the global portfolio of antimalarial medicines,and highlight challenges and patient specific concerns of these novel molecules.We discuss different clinical studies focusing on the evaluation of novel drugs against malaria in different human trials over the past five years.The drugs KAE609 and DDD107498 are still being evaluated in Phase I trials and preclinical developmental studies.Both the safety and efficacy of novel compounds such as KAF156 and DSM265 need to be assessed further,especially for use in pregnant women.Synthetic non-artemisinin ozonides such as OZ277 raised concerns in terms of its insufficient efficacy against high parasitic loads.Aminoquinoline-based scaffolds such as ferroquine are promising but should be combined with good partner drugs for enhanced efficacy.AQ-13 induced electrocardiac events,which led to prolonged QTc intervals.Tafenoquine,the only new anti-relapse scaffold for patients with a glucose-6-phosphate dehydrogenase deficiency,has raised significant concerns due to its hemolytic activity.Other compounds,including methylene blue(potential transmission blocker)and fosmidomycin(DXP reductoisomerase inhibitor),are available but cannot be used in children.At this stage,we are unable to identify a single magic bullet against malaria.Future studies should focus on effective single-dose molecules that can act against all stages of malaria in order to prevent transmission.Newer medicines have also raised concerns in terms of efficacy and safety.Overall,more evidence is needed to effectively reduce the current malaria burden.Treatment strategies that target the blood stage with transmission-blocking properties are needed to prevent future drug resistance.Akshaya Srikanth Bhagavathula Asim Ahmed Elnour Abdulla Shehab 2016Infectious Diseases of Poverty2016,5,1:1
16A review on chemical coagulation/flocculation technologies for removal of colour from textile wastewaters显示文摘Akshaya K V Rajesh R D Puspendu B 2012Journal of Environmental Management2012,93,1:1
17Input-output linearization and robust sliding mode controller for the VSC-HVDC transmission link显示文摘Akshaya Moharana Dash P K 2010IEEE Transactions on Power Delivery2010,25,1:1
18Input-output linearization and robust sliding-mode controller for the VSC-HVDC transmission link显示文摘AKSHAYA MOHARANA DASH P K 2010IEEE Transactions on Power Delivery2010,25,3:1
19SQL-BASED Approach to Distributed and Incremental Association Rule Mining显示文摘Himavali K Shama C Akshaya A 2006Foundations of Computing and Decision Sciences2006,31,1:1
20SSR Alleviation by STATCOM in Induction Generator-Based Wind Farm Connected to Series Compensated Line显示文摘AKSHAYA M RAJIV K V RAVI S 2014IEEE Transac-tions on Sustainable Energy2014,5,3:1
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