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| 1 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 2 |
| 2 | Variations in the characteristics of keratocytes in culture in relation to their location in human cornea显示文摘 | Nicolas Builles Nicolas Bechetoille Virginie Justin Valérie André Carole Burillon Odile Damour | 2008 | Bio-Medical Materials and Engineering2008，，1： | 1 |
| 3 | Real-time Dynamic Control of a Stewart Platform显示文摘 | Nicolas Andres Ordoez Carlos Francisco Rodriguez | 2013 | Applied Mechanics and Materials2013，390，8： | 1 |
| 4 | Optical quantum random number generator显示文摘 | Andre Stefanov Nicolas Gisin Olivier Guinnard Laurent Guinnard Hugo Zbinden | 2000 | Journal of Modern Optics2000，，4： | 1 |
| 5 | Learning and removing cast shadows through a multidistribution approach显示文摘 | Nicolas M B Andre Z | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，7： | 1 |
| 6 | Importance of routine mediastinal staging in women with non-small cell lung cancer显示文摘 | Martin de Nicolas J Gomez-Caro Andres A Moradiellos Diez FJ | 2005 | Arch Bronconeumol2005，41，3： | 1 |
| 7 | MyCTC chip:microfluidic-based drug screen with patient-derived tumour cells from liquid biopsies显示文摘Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns,often leading to ineffective treatment.Current clinical practice for treatment decision-making is commonly based on primary or secondary tumour biopsies,yet when disease progression accelerates,tissue biopsies are not performed on a regular basis.It is in this context that liquid biopsies may offer a unique window to uncover key vulnerabilities,providing valuable information about previously underappreciated treatment opportunities.Here,we present MyCTC chip,a novel microfluidic device enabling the isolation,culture and drug susceptibility testing of cancer cells derived from liquid biopsies.Cancer cell capture is achieved through a label-free,antigen-agnostic enrichment method,and it is followed by cultivation in dedicated conditions,allowing on-chip expansion of captured cells.Upon growth,cancer cells are then transferred to drug screen chambers located within the same device,where multiple compounds can be tested simultaneously.We demonstrate MyCTC chip performance by means of spike-in experiments with patientderived breast circulating tumour cells,enabling>95%capture rates,as well as prospective processing of blood from breast cancer patients and ascites fluid from patients with ovarian,tubal and endometrial cancer,where sensitivity to specific chemotherapeutic agents was identified.Together,we provide evidence that MyCTC chip may be used to identify personalized drug response patterns in patients with advanced metastatic disease and with limited treatment opportunities. | Fabienne D.Schwab Manuel C.Scheidmann Lauren L.Ozimski AndréKling Lucas Armbrecht Till Ryser Ilona Krol Karin Strittmatter Bich Doan Nguyen-Sträuli Francis Jacob AndréFedier Viola Heinzelmann-Schwarz Andreas Wicki Petra S.Dittrich Nicola Aceto | 2022 | Microsystems & Nanoengineering2022，8，6： | 1 |
| 8 | Optical quantum random number generator显示文摘 | Andre Stefanov Nicolas Gisin Olivier Guinnard Laurent Guinnard Hugo Zbinden | 2000 | Journal of Modern Optics2000，，4： | 1 |
| 9 | Probabilistic consensus clustering using evidence accumulation显示文摘 | Andr Laurenco Samuel Rota Bulo Nicola Rebagliati | 2013 | Machine Learning2013，，4： | 1 |
| 10 | MicroRNA regulation of Alzheimer’s Amyloid precursor protein expression显示文摘 | Sébastien S. Hébert Katrien Horré Laura Nicola? Bruno Bergmans Aikaterini S. Papadopoulou André Delacourte Bart De Strooper | 2009 | Neurobiology of Disease2009，，3： | 1 |
| 11 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 1 |
| 12 | Geotrichum candidum septicemia in a child with hepatoblastoma显示文摘 | Nicolas André Carole Coze Jean Claude Gentet Rolande Perez Jean Louis Bernard | 2004 | The Pediatric Infectious Disease Journal2004，，1： | 1 |
| 13 | Molecular and biochemical characterization of endo-β-mannanases from germinating coffee (Coffea arabica) grains显示文摘 | Pierre Marraccini John W. Rogers Cyril Allard Marie-Laure André Victoria Caillet Nicolas Lacoste Fran?oise Lausanne Stéphane Michaux | 2001 | Planta2001，，2： | 1 |
| 14 | Development of a combined isotopic and mass-balance approach to determine dissolved organic carbon sources in eutrophic reservoirs显示文摘 | Anne-Catherine Pierson-Wickmann Gérard Gruau Emilie Jardé Nicolas Gaury Luc Brient Marion Lengronne André Crocq Daniel Helle Thibault Lambert | 2010 | Chemosphere2010，，3： | 1 |
| 15 | Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages显示文摘 | Laurent L’homme Nathalie Esser Laura Riva André Scheen Nicolas Paquot Jacques Piette Sylvie Legrand-Poels | 2013 | The Journal of Lipid Research2013，，11： | 1 |
| 16 | Molecular and biochemical characterization of endo-β-mannanases from germinating coffee (Coffea arabica) grains显示文摘 | Pierre Marraccini John W. Rogers Cyril Allard Marie-Laure André Victoria Caillet Nicolas Lacoste Fran?oise Lausanne Stéphane Michaux | | 0，，： | 1 |
| 17 | Neuroprotective Effects of Propofol in a Model of Ischemic Cortical Cell Cultures: Role of Glutamate and Its Transporters显示文摘 | Lionel J. Velly Benjamin A. Guillet Frederique M. Masmejean André L. Nieoullon Nicolas J. Bruder Fran?ois M. Gouin Pascale M. Pisano | 2003 | Anesthesiology2003，，2： | 1 |
| 18 | Non-invasive ventilation after extubation in hypercapnic patients with chronic respiratory disorders: randomised controlled trial显示文摘 | Miquel Ferrer Jacobo Sellarés Mauricio Valencia Andres Carrillo Gumersindo Gonzalez Joan Ramon Badia Josep Maria Nicolas Antoni Torres | 2009 | The Lancet2009，，9695： | 1 |
| 19 | Literature and Practice: A Critical Review of MOOCs 显示文摘 | Chiappe-Laverde A_ndres Hine Nicolas Martinez-Silva Jose - Andres | 2015 | COMUNICAR2015，1，44： | 1 |
| 20 | Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes显示文摘 | Nathalie Esser Sylvie Legrand-Poels Jacques Piette André J. Scheen Nicolas Paquot | 2014 | Diabetes Research and Clinical Practice2014，，： | 1 |
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