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5篇 您的检索式:作者名="Andrea Spoto"
    题名 作者 年代 出处 被引量
1Carbonized nano/microparticles for enhanced mechanical properties and electromagnetic interference shielding of cementitious materials显示文摘在现在的工作,碳 nano/microparticles 由花生(PS ) 的控制热分解获得了,榛子(HS ) 壳被介绍。这些材料被拉曼光谱学和地 emissionscanning 电子显微镜学(FE-SEM ) 描绘。当增加了水泥浆糊时,直到 1 wt% ,这些材料导致了水泥矩阵的增加曲折力量并且坚韧。而且关于平凡水泥,当在水泥 composites 增加 PS 或 HS 的 0.5 wt% 与相比是高得多的时,防护效果的电磁的放射的全部的增加为 CNT 在文学报导了,在一样的内容使用。Rao Arsalan KHUSHNOOD Sajjad AHMAD Luciana RESTUCCIA Consuelo SPOTO Pravin JAGDALE Jean-Marc TULLIANI Giuseppe Andrea FERRO 2016Frontiers of Structural and Civil Engineering2016,0,2:4
2Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer显示文摘Giuseppe Perrone Pier Adelchi Ruffini Vincenzo Catalano Cathie Spino Daniele Santini Pietro Muretto Chiara Spoto Costantino Zingaretti Valerio Sisti Paolo Alessandroni Paolo Giordani Andrea Cicetti Silvia D’Emidio Sergio Morini Annamaria Ruzzo Mauro Magna 2008European Journal of Cancer2008,,13:1
3Social Network Analysis : A brief theoretical review and further perspectives in the study of Information Technology 显示文摘Francesco Martino Andrea Spoto 2006PsychNology Journal2006,4,:1
4Social Network Analysis: A brief theoretical review and further perspectives in the study of Information Technology 显示文摘Francesco Martino Andrea Spoto 2006PsychNology Journal2006,4,1:1
5Memantine: New prospective in bipolar disorder treatment显示文摘We review preclinical and clinical evidences strongly suggesting that memantine, an old drug currently approved for Alzheimer's dementia, is an effective treatment for acute mania and for the prevention of manic/hypomanic and depressive recurrences of manicdepressive illness. Lithium remains the first line for the treatment and prophylaxis of bipolar disorders, but currently available treatment alternatives for lithium resistant patients are of limited and/or questionable efficacy. Thus, research and development of more effective mood stabilizer drugs is a leading challenge for modern psychopharmacology. We have demonstrated that 21 d administration of imipramine causes a behavioural syndrome similar to a cycle of bipolar disorder, i.e., a mania followed by a depression, in rats. Indeed, such treatment causes a behavioural supersensitivity to dopamine D2 receptor agonists associated with an increase sexual activity and aggressivity(mania). The dopamine receptor sensitization is followed, after imipramine discontinuation, by an opposite phenomenon(dopamine receptor desensitization) and an increased immobility time(depression) in the forced swimming test of depression. Memantine blocks the development of the supersensitivity and the ensuing desensitization associated with the depressive like behavior. On the basis of these observations we have suggested the use of memantine in the treatment of mania and in the prophylaxis of bipolar disorders. To test this hypothesis we performed several naturalistic studies that showed an acute antimanic effect and a long-lasting and progressive mood-stabilizing action(at least 3 years), without clinically relevant side effects. To confirm the observations of our naturalistic trials we are now performing a randomized controlled clinical trial. Finally we described the studies reporting the efficacy of memantine in maniclike symptoms occurring in psychiatric disorders other than bipolar. Limitations: A randomized controlled clinical trial is needed to confirm our naturalistic observations.Conclusion: We believe that this review presents enough pharmacological and clinical information to consider the administration of memantine in the treatment of bipolar disorders that no respond to standard mood stabilizers.Giulia Serra Francesca Demontis Francesca Serra Lavinia De Chiara Andrea Spoto Paolo Girardi Giulio Vidotto Gino Serra 2014World Journal of Psychiatry2014,4,4:0
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