|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | lnflamm&Won &nd long term morality in &cute congestive heart fsilure显示文摘 | Christi&n M Kitten LK Andrezs C et &l | 2006 | Am He&rt J2006，15，4： | 1 |
| 2 | Influence of recycled concrete on mechanical properties of HS/HPC显示文摘 | Andreze J Ajdukiewic Z Alina K liszcewica | 2002 | Cement and concrete composites2002，24，2： | 1 |
| 3 | Generation automa-tique et simplification des equations litterales des systemesmecaniques articules显示文摘 | Andrez E Losco L Andre P Taillard J P | 1985 | Mechanism and Machine Theory1985，20，3： | 1 |
| 4 | Nitric oxide protects the ultrastructure of pancreatic acinar cells in the course of caerulein induced acute pancreatitis 显示文摘 | Andrez JA Jurkowska G | 1999 | Int J Exp Pathol1999，80，6： | 1 |
| 5 | Modificationofgrowthkineticsinsurfactant-mediatedepitaxy显示文摘 | BERTV ANDREZ THOMASW etal | 1995 | PhysRevB1995，51，： | 1 |
| 6 | Perceived social support as an offshoot of attachment style显示文摘 | Jo?o M Moreira Maria de Fátima Silva Carla Moleiro Patr??cia Aguiar Micael Andrez Sónia Bernardes Helena Afonso | 2002 | Personality and Individual Differences2002，，3： | 1 |
| 7 | Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases:new perspectives显示文摘Various conditions affecting nerve cells and the nervous system due to the loss of neurons and their connecting networks are described under the superordinate phrase“Neurodegenerative diseases”.Such diseases lead to disability due to gradual neuronal death in both the central nervous system and the peripheral nervous system.While many of these diseases have unknown causes,sometimes these are due to medical conditions such as alcoholism,a tumor,or a stroke,or other causes which may include genetic mutations,toxins,chemicals,and viruses. | Gustavo de Bem Silveira Alexandre Pastoris Muller Ricardo Andrez Machado-de-Ávila Paulo Cesar Lock Silveira | 2021 | Neural Regeneration Research2021，16，12： | 0 |
| 8 | Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice显示文摘Fibromyalgia(FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still unknown, a significant decrease in biogenic amines is a common characteristic in its pathogenesis. Here, our main objective was to investigate the role of dopamine D3/D2 receptor during the reserpine-induced pain in mice. Our results showed that pramipexole(PPX) – a dopaminergic D3/D2 receptor agonist – inhibited mechanical allodynia and thermal sensitivity induced by reserpine. Relevantly, PPX treatment decreased immobility time and increased the number of grooming in the forced swimming test and splash test, respectively. Animals that received PPX remained longer in the open arms than the reserpine group using elevated plusmaze apparatus. The repeated PPX administration, given daily for 4 days, significantly blocked the mechanical and thermal allodynia during FM model, similarly to pregabalin, although it failed to affect the reserpine-induced thermal nociception. Reserpine administration induced significant downregulation of dopamine concentration in the central nervous system, and repeated treatment with PPX restored dopamine levels in the frontal cortex and spinal cord tissues. Moreover, PPX treatment inhibited oxidants production such as DCFH(2′,7′-dichlorodihydrofluorescein) and nitrite, also decreased oxidative damage(carbonyl), and upregulated the activity of superoxide dismutase in the spinal cord. Together, our findings demonstrated the ability of dopamine D3/D2 receptor-preferring agonist in reducing pain and mood dysfunction allied to FM in mice. All experimental protocols were approved by the Universidade Federal de Santa Catarina(UFSC) Ethics Committee(approval No. 2572210218) on May 10, 2018. | Carlos Pereira Martins Rodrigo Sebben Paes Gabriela Mantovani Baldasso Eduarda Gomes Ferrarini Rahisa Scussel Rubya Pereira Zaccaron Ricardo Andrez Machado-de-Avila Paulo Cesar Lock Silveira Rafael Cypriano Dutra | 2022 | Neural Regeneration Research2022，17，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员