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| 1 | Cell Death Mechanisms Induced by Cytotoxic Lymphocytes显示文摘One of the functions of the immune system is to recognize and destroy abnormal or infected cells to maintain homeostasis. This is accomplished by cytotoxic lymphocytes. Cytotoxicity is a highly organized multifactor process. Here,we reviewed the apoptosis pathways induced by the two main cytotoxic lymphocyte subsets,natural killer(NK) cells and CD8+ T cells. In base to recent experimental evidence,we reviewed NK receptors involved in recognition of target-cell,as well as lytic molecules such as perforin,granzymes-A and-B,and granulysin. In addition,we reviewed the Fas-FasL intercellular linkage mediated pathway,and briefly the cross-linking of tumor necrosis factor(TNF) and TNF receptor pathway. We discussed three models of possible molecular interaction between lytic molecules from effector cytotoxic cells and target-cell membrane to induction of apoptosis. | Chávez-Galán L Arenas-Del Angel MC Zenteno E Chávez R Lascurain R | 2009 | Cellular & Molecular Immunology2009，6，1： | 17 |
| 2 | Epigenetic basis of Alzheimer disease显示文摘Alzheimer disease(AD)is the primary form of dementia that occurs spontaneously in older adults.Interestingly,the epigenetic profile of the cells forming the central nervous system changes during aging and may contribute to the progression of some neurodegenerative diseases such as AD.In this review,we present general insights into relevant epigenetic mechanisms and their relationship with aging and AD.The data suggest that some epigenetic changes during aging could be utilized as biomarkers and target molecules for the prevention and control of AD. | Angeles C Tecalco-Cruz JosuéO Ramírez-Jarquín María E Alvarez-Sánchez Jesus Zepeda-Cervantes | 2020 | World Journal of Biological Chemistry2020，11，2： | 4 |
| 3 | Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial显示文摘 | Thomas E Hutson Vladimir Lesovoy Salman Al-Shukri Viktor P Stus Oleg N Lipatov Angel H Bair Brad Rosbrook Connie Chen Sinil Kim Nicholas J Vogelzang | 2013 | Lancet Oncology2013，，13： | 2 |
| 4 | Vitamin D Treatment and Mortality in Chronic Kidney Disease: A Systematic Review and Meta-Analysis显示文摘 | Duranton Flore Rodriguez-ortiz Maria E Duny Yohan Rodriguez Mariano Daur?s Jean-pierre Argil?s Angel | 2013 | American Journal of Nephrology2013，，3： | 2 |
| 5 | Increased prevalence and analysis of risk factors for indinavir nephrolithiasis显示文摘 | ANGEL JB FUTTER NG | 2000 | J Urol2000，164，6： | 1 |
| 6 | Theoretical com- parison of low GWP alternatives for different refrigeration configurations taking R404A as baseline显示文摘 | Adrian M B Joaquin N E Angel B | 2014 | International Journal of Refrigeration2014，44，1： | 1 |
| 7 | 显示文摘 | CORT(E)S-J(A)COME M A ESCOBAR J ANGELES CH(A)VEZ C LPEZ-SALINAS E ROMERO E FERRAT G TOLEDO-ANTONIO J A | 2008 | Catal Today2008，130，1： | 1 |
| 8 | Comparative assessment of solid-phase extraction clean-up procedures,GC columns and perfluoroacylation reagents for determination of type B trichothecenes in wheat by GC-ECD显示文摘 | FRANCISCO M V A ANGEL M JOS(E) V G A | 2005 | Talanta2005，66，： | 1 |
| 9 | Joint TDOA and FDOA estimation: aconditional bound and its use for optimally weighted localization 显示文摘 | Yeredor A Angel E | 2011 | IEEE Transactions on Signal Processing2011，59，4： | 1 |
| 10 | Drop-in energy performance evaluation of R1234yf and R1234ze(E) in a vapor compression system as R134a replacements 显示文摘 | Adrian M B Joaquin N E Angel B | 2014 | Ap- plied Thermal Engineering2014，71，1： | 1 |
| 11 | Prelimi nary nitrogen, phosphorus, and potassium DRIS norms for pineapple 显示文摘 | Angeles D E Sumner M E Barbour N W | 1990 | HortScience1990，25，6： | 1 |
| 12 | Genetics of resistance of rice cultivar ARC10550 to Bangladesh brown pianthopper teletype显示文摘 | Gurdev S Khush A N M Rezaul Karim E R Angeles | 1985 | Journal of Genetics (-)1985，，2： | 1 |
| 13 | Pyramiding of bacterial blight resistance genes in rice: marker assisted selection using RFLP and PCR显示文摘 | Huang N Angeles E R Domingo J | 1997 | Theor Appl Genet1997，95，： | 1 |
| 14 | Free radical scavengers, anti-inflammatory and analgesic activity of Acaena magellanica显示文摘 | Feresin G E Tapia A Angel G R | 2002 | Journal of Pharmacy and Pharmacology2002，54，6： | 1 |
| 15 | Pyramiding of bacterial blight resistance genes in rice : Marker - Assisted Selection using RFLP and PCR显示文摘 | Huang N Angeles E R Domingo J | 1996 | Theor Appl Genet1996，95，： | 1 |
| 16 | Faster anaerobic decomposition of a brittle straw rice mutant:implications for residue management显示文摘 | JOHNSON S E ANGELES O R BRAR D S | | 0，，7： | 1 |
| 17 | Joint TDOA and FDOA estimation: a conditio- nal bound and its use for optimally weighted localization 显示文摘 | Yeredor A Angel E | 2011 | IEEE Trans on Signal Processing2011，59，4： | 1 |
| 18 | Laparoscopic diagnosis of acute lower abdominal pain in women of reproductive age显示文摘 | Gaitan H Angel E Sanchez J | 2002 | Int J Gynaecol Obstet2002，76，2： | 1 |
| 19 | Aromatic polyamides with benzothiazole pendent groups: synthesis, nuclear mag- netic resonance structural study and evaluation of properties 显示文摘 | ANGEL E L JOSE G C JAVIER A | 1994 | Polymer1994，35，4： | 1 |
| 20 | Cytokinin oxidase regulates rice grain production显示文摘 | Ashikari M Sakakibara H Lin S Y Yamamoto T Takashi T Nishimura A Angeles E R Qian Q Kitano H Matsuoka M | 2005 | Science2005，309，： | 1 |
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