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| 1 | Ischemic colitis:Clinical practice in diagnosis and treatment显示文摘Ischemic colitis is the most common form of ischemic injury of the gastrointestinal tract and can present either as an occlusive or a non-occlusive form. It accounts for 1 in 1000 hospitalizations but its incidence is underesti- mated because it often has a mild and transient nature. The etiology of ischemic colitis is multifactorial and the clinical presentation variable. The diagnosis is based on a combination of clinical suspicion, radiographic, endo- scopic and histological findings. Therapy and outcome depends on the severity of the disease. Most cases of the non-gangrenous form are transient and resolve spontaneously without complications. On the other hand, high morbidity and mortality and urgent operative intervention are the hallmarks of gangrenous ischemic colitis. | Angeliki Theodoropoulou Ioannis E Koutroubakis | 2008 | World Journal of Gastroenterology2008，14，48： | 75 |
| 2 | Red blood cell distribution width in elderly hospitalized patients with cardiovascular disease显示文摘BACKGROUND Red blood cell distribution width(RDW)is elevated in patients with cardiovascular disease(CVD).AIM To determine RDW values and impact of CV and non-CV coexisting morbidities in elderly patients hospitalized with chronic CVD.METHODS This prospective study included 204 consecutive elderly patients(age 77.5[7.41]years,female 94[46%],left ventricular ejection fraction 53.00%[37.50,55.00])hospitalized with chronic CVD at the Cardiology Department of Larissa University General Hospital(Larissa,Greece)from January 2019 to April 2019.Elderly patients were selected due to the high prevalence of coexisting morbidities in this patient population.Hospitalized patients with acute CVD(acute coronary syndromes,new-onset heart failure[HF],and acute pericarditis/myocarditis),primary isolated valvular heart disease,sepsis,and those with a history of blood transfusions or cancer were excluded.The evaluation of the patients within 24 h from admission included clinical examination,laboratory blood tests,and echocardiography.RESULTS The most common cardiac morbidities were hypertension and coronary artery disease,with acutely decompensated chronic heart failure(ADCHF)and atrial fibrillation(AF)also frequently being present.The most common non-cardiac morbidities were anemia and chronic kidney disease followed by diabetes mellitus,chronic obstructive pulmonary disease,and sleep apnea.RDW was significantly elevated 15.48(2.15);121(59.3%)of patients had RDW>14.5%which represents the upper limit of normal in our institution.Factors associated with RDW in stepwise regression analysis were ADCHF(coefficient:1.406;95%confidence interval[CI]:0.830-1.981;P<0.001),AF(1.192;0.673 to 1.711;P<0.001),and anemia(0.806;0.256 to 1.355;P=0.004).ADCHF was the most significant factor associated with RDW.RDW was on average 1.41 higher for patients with than without ADCHF,1.19 higher for patients with than without AF,and 0.81 higher for patients with than without anemia.When patients were grouped based on the presence or absence of anemia,ADCHF and AF,heart rate was not increased in those with anemia but was significantly increased in those with ADCHF or AF.CONCLUSION RDW was elevated in elderly hospitalized patients with chronic CVD.Factors associated with RDW were anemia and CV factors associated with elevated heart rate(ADCHF,AF),suggesting sympathetic overactivity. | Andrew Xanthopoulos Konstantinos Tryposkiadis Apostolos Dimos Angeliki Bourazana Alexandros Zagouras Nikolaos Iakovis Michail Papamichalis Grigorios Giamouzis George Vassilopoulos John Skoularigis Filippos Triposkiadis | 2021 | World Journal of Cardiology2021，13，9： | 13 |
| 3 | Prevalence of hepatitis B and C markers among refugees in Athens显示文摘AIM: To assess the prevalence of hepatitis B and C serological markers in a population of refugees living in Athens.METHODS: One hundred and thirty refugees (81 males and 49 females, mean age ±SD: 31.7±8 years) were included in the study. The hepatitis B virus surface antigen (HBsAg),the hepatitis B virus core antibody (anti-HBc) and the hepatitis C virus antibody (anti-HCV) were detected using a third-generation immunoassay.RESULTS: Twenty individuals (15.4%) were HBsAg positive and 69 (53.1%) were anti-HBc positive. The prevalence of HBsAg and anti-HBc was higher among refugees from Albania and Asia (statistical significant difference, P<0.008 and P<0.001 respectively). The prevalence of these markers was found irrelevant to age or sex. Anti-HCV was detected in the serum of 3 individuals (2.3 %). No differences among age, sex or ethnicity regarding anti-HCV prevalence were found.CONCLUSION: It can be concluded that refugees living in Athens are an immigrant population characterized by a high incidence of HBV infection. The prevalence of HBV markers is higher among refugees from Albania and Asia. It is therefore believed that the adherence to general precautions and the initiation of HBV vaccination programs will be necessary in the future, especially in these communities.Although the prevalence of HCV infection seems to be relatively low, extended epidemiological surveys are needed to provide valid results. | Anastasios Roussos Constantin Goritsas Thomas Pappas Maria Spanaki Panagiota Papadaki Angeliki Ferti | 2003 | World Journal of Gastroenterology2003，9，5： | 11 |
| 4 | Metabolic inflammation as an instigator of fibrosis during nonalcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is characterized by excessive storage of fatty acids in the form of triglycerides in hepatocytes.It is most prevalent in western countries and includes a wide range of clinical and histopathological findings,namely from simple steatosis to steatohepatitis and fibrosis,which may lead to cirrhosis and hepatocellular cancer.The key event for the transition from steatosis to fibrosis is the activation of quiescent hepatic stellate cells(qHSC)and their differentiation to myofibroblasts.Pattern recognition receptors(PRRs),expressed by a plethora of immune cells,serve as essential components of the innate immune system whose function is to stimulate phagocytosis and mediate inflammation upon binding to them of various molecules released from damaged,apoptotic and necrotic cells.The activation of PRRs on hepatocytes,Kupffer cells,the resident macrophages of the liver,and other immune cells results in the production of proinflammatory cytokines and chemokines,as well as profibrotic factors in the liver microenvironment leading to qHSC activation and subsequent fibrogenesis.Thus,elucidation of the inflammatory pathways associated with the pathogenesis and progression of NAFLD may lead to a better understanding of its pathophysiology and new therapeutic approaches. | Angeliki Katsarou Ioannis I Moustakas Iryna Pyrina Panagiotis Lembessis Michael Koutsilieris Antonios Chatzigeorgiou | 2020 | World Journal of Gastroenterology2020，26，17： | 9 |
| 5 | The omega-3 and retinopathy of prematurity relationship显示文摘The aim of this article is to examine the effect of omega-3(ω-3) long-chain polyunsaturated fatty acids(LCPUFAs) intake on retinopathy of prematurity(ROP) by reviewing the experimental and clinical trials conducted on animal models and infants.LCPUFAs demonstrate cytoprotective and cytotherapeutic actions contributing to a number of anti-angiogenic and neuroprotective mechanisms within the retina.Their intake appears to have a beneficial effect on ischemia,oxidative stress,inflammation and cellular signaling mechanisms,influencing retinal cell gene expression and cellular differentiation.ω-3 LCPUFAs may modulate metabolic processes that activate molecules implicated in the pathogenesis of vasoproliferative and neurodegenerative retinal diseases such as ROP. | Angelakis Malamas Angeliki Chranioti Christos Tsakalidis Stavros A Dimitrakos Asimina Mataftsi | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 4 |
| 6 | Metalloproteinase expression after desflurane preconditioning in hepatectomies:A randomized clinical trial显示文摘BACKGROUND Hepatectomy with inflow occlusion results in ischemia-reperfusion injury;however,pharmacological preconditioning can prevent such injury and optimize the postoperative recovery of hepatectomized patients.The normal inflammatory response after a hepatectomy involves increased expression of metalloproteinases,which may signal pathologic hepatic tissue reformation.AIM To investigate the effect of desflurane preconditioning on these inflammatory indices in patients with inflow occlusion undergoing hepatectomy.METHODS This is a single-center,prospective,randomized controlled trial conducted at the 4th Department of Surgery of the Medical School of Aristotle University of Thessaloniki,between August 2016 and December 2017.Forty-six patients were randomized to either the desflurane treatment group for pharmacological preconditioning(by replacement of propofol with desflurane,administered 30 min before induction of ischemia)or the control group for standard intravenous propofol.The primary endpoint of expression levels of matrix metalloproteinases and their inhibitors was determined preoperatively and at 30 min posthepatic reperfusion.The secondary endpoints of neutrophil infiltration,coagulation profile,activity of antithrombin III(AT III),protein C(PC),protein S and biochemical markers of liver function were determined for 5 d postoperatively and compared between the groups.RESULTS The desflurane treatment group showed significantly increased levels of tissue inhibitor of metalloproteinases 1 and 2,significantly decreased levels of matrix metalloproteinases 2 and 9,decreased neutrophil infiltration,and less profound changes in the coagulation profile.During the 5-d postoperative period,all patients showed significantly decreased activity of AT III,PC and protein S(vs baseline values,P<0.05).The activity of AT III and PC differed significantly between the two groups from postoperative day 1 to postoperative day 5(P<0.05),showing a moderate drop in activity of AT III and PC in the desflurane treatment group and a dramatic drop in the control group.Compared to the control group,the desflurane treatment group also had significantly lower international normalized ratio values on all postoperative days(P<0.005)and lower serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase values on postoperative days 2 and 3(P<0.05).Total length of stay was significantly less in the desflurane group(P=0.009).CONCLUSION Desflurane preconditioning can lessen the inflammatory response related to ischemia-reperfusion injury and may shorten length of hospitalization. | Eleni Koraki Ioannis Mantzoros Christos Chatzakis Anna Gkiouliava Angeliki Cheva Athina Lavrentieva Freideriki Sifaki Helena Argiriadou Isaak Kesisoglou Konstantinos Galanos-Demiris Stefanos Bitsianis Konstantinos Tsalis | 2020 | World Journal of Hepatology2020，12，11： | 4 |
| 7 | Design of hospital healing gardens linked to pre- or post-occupancy research findings显示文摘 | Angeliki Triandafillou Paraskevopoulou Emmanouela Kamperi | 2018 | Frontiers of Architectural Research2018，7，3： | 3 |
| 8 | Midgut neuroendocrine tumor presenting with acute intestinal ischemia显示文摘Neuroendocrine tumors represent a heterogeneous group of neoplasms that arise from neuroendocrine cells and secrete various peptides and bioamines. While gastrointestinal neuroendocrine tumors,commonly called carcinoids,account for about 2/3 of all neuroendocrine tumors,they are relatively rare. Small intestine neuroendocrine tumors originate from intestinal enterochromaffin cells and represent about 1/4 of small intestine neoplasms. They can be asymptomatic or cause nonspecific symptoms,which usually leads to a delayed diagnosis. Imaging modalities can aid diagnosis and surgery remains the mainstay of treatment. We present a case of a jejunal neuroendocrine tumor that caused nonspecific symptoms for about 1 year before manifesting with acute mesenteric ischemia. Abdominal X-rays revealed pneumatosis intestinalis and an abdominal ultrasound and computed tomography confirmed the diagnosis. The patient was submitted to segmental enterectomy. Histopathological study demonstrated a neuroendocrine tumor with perineural and arterial infiltration and lymph node metastasis. The postoperative course was uneventful and the patient denied any adjuvant treatment. | Ioannis Mantzoros Natalia Antigoni Savvala Orestis Ioannidis Styliani Parpoudi Lydia Loutzidou Despoina Kyriakidou Angeliki Cheva Vasileios Intzos Konstantinos Tsalis | 2017 | World Journal of Gastroenterology2017，23，45： | 2 |
| 9 | Effects of chromium (VI) addition on the activated sludge process显示文摘 | Athanasios S Stasinakis Nikolaos S Thomaidis Daniel Mamais Evangelia C Papanikolaou Angeliki Tsakon Themistokles D Lekkas | 2002 | Water Research2002，，9： | 2 |
| 10 | Clinical and Genetic Characterization of Families With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Provides Novel Insights Into Patterns of Disease Expression显示文摘 | Srijita Sen-Chowdhry Petros Syrris Deirdre Ward Angeliki Asimaki Elias Sevdalis William J. McKenna | 2007 | Circulation2007，，13： | 2 |
| 11 | Evaluating OpenFace:an open-source automatic facial comparison algorithm for forensics显示文摘This article studies the application of models of OpenFace(an open-source deep learning algorithm)to forensics by using multiple datasets.The discussion focuses on the ability of the software to identify similarities and differences between faces based on images from forensics.Experiments using OpenFace on the Labeled Faces in the Wild(LFW)-raw dataset,the LFW-deep funnelled dataset,the Surveillance Cameras Face Database(SCface)and ForenFace datasets showed that as the resolution of the input images worsened,the effectiveness of the models degraded.In general,the effect of the quality of the query images on the efficiency of OpenFace was apparent.Therefore,OpenFace in its current form is inadequate for application to forensics,but can be improved to offer promising uses in the field. | Angeliki Fydanaki Zeno Geradts | 2018 | Forensic Sciences Research2018，3，3： | 2 |
| 12 | Epithelial–mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic显示文摘 | Angeliki Voulgari Alexander Pintzas | 2009 | BBA - Reviews on Cancer2009，，2： | 2 |
| 13 | Ciprofloxacin and probiotic Escherichia coli Nissle add-on treatment in active ulcerative colitis: A double-blind randomized placebo controlled clinical trial显示文摘 | Andreas Munk Petersen Hengameh Mirsepasi Sofie Ingdam Halkj?r Esben Munk Mortensen Inge Nordgaard-Lassen Karen Angeliki Krogfelt | 2014 | Journal of Crohn’s and Colitis2014，，11： | 2 |
| 14 | Emergence of Escherichia coli sequence type 410 (ST410) with KPC-2 β-lactamase显示文摘 | Angeliki Mavroidi Vivi Miriagou Ergina Malli Angelos Stefos George N. Dalekos Leonidas S. Tzouvelekis Efthymia Petinaki | 2011 | International Journal of Antimicrobial Agents2011，，3： | 1 |
| 15 | Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes显示文摘 | Angeliki G Omer A Michael Y | 2000 | J Clin Endocrinol Metab2000，85，9： | 1 |
| 16 | I,uteolin inhibits an endotoxin-stimulated phosphorylation cascade and proin- flammatory cytokine production in macrophages 显示文摘 | Angeliki X Andreas P Antonis M et a| | 2001 | Phar- macol Exp Ther2001，296，1： | 1 |
| 17 | Cro6s - lay- er resource allocation in medium - voltage broadband o- ver power - line networks 显示文摘 | Angeliki M S Athanasios ED Panayotis CC | 2012 | IEEE Transactions on Power Dellvery2012，27，4： | 1 |
| 18 | Polymorphisms in the Fatty Acid-Binding Protein 2 and Apolipoprotein C-III Genes Are Associated with the Metabolic Syndrome and Dyslipidemia in a South Indian Population显示文摘 | Jean-Marc Guettier Angeliki Georgopoulos Michael Y. Tsai Venkatesan Radha Subramaniam Shanthirani Raj Deepa Myron Gross Gundu Rao Viswanathan Mohan | 2005 | The Journal of Clinical Endocrinology & Metabolism2005，，3： | 1 |
| 19 | Association between thrombocytosis and iron deficiency anemia in inflammatory bowel disease显示文摘 | Evangelos Voudoukis Konstantinos Karmiris Pantelis Oustamanolakis Angeliki Theodoropoulou Aekaterini Sfiridaki Gregorios A. Paspatis Ioannis E. Koutroubakis | 2013 | European Journal of Gastroenterology & Hepatology2013，，10： | 1 |
| 20 | 'Smart' polymeric microfluidics fabricated by plasma processing: Controlled wetting,capillary filling and hydrophobic valving 显示文摘 | Katerina Tsougeni Dimitris Papageorgiou Angeliki Tserepi | 2010 | Lab on a Chip2010，10，： | 1 |
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