维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

8篇 您的检索式：作者名="Anne Lyons"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	A Randomized Controlled Comparison of Flushing Protocols in Home Care Patients With Peripherally Inserted Central Catheters显示文摘	Margaret G. Lyons Ann G. Phalen	2014	Journal of Infusion Nursing2014，，4：	1
	2	Electrode systems for continuous monitoring in cardiovascular surgery显示文摘	CLARK-JR L C LYONS C ANN N Y	1962	Acad Sci1962，102，：	1
	3	A Common Variant of the Endothelial Nitric Oxide Synthase (Glu298→Asp) Is a Major Risk Factor for Coronary Artery Disease in the UK显示文摘	Aroon D. Hingorani Chia Fan Liang Jenny Fatibene Amelia Lyon Sue Monteith Ann Parsons Stephen Haydock Ruth V. Hopper Nigel G. Stephens Kevin M. O’Shaughnessy Morris J. Brown	1999	Circulation1999，，14：	1
	4	Electrode Systems for Continuous Monitoring in Cardiovascular Surgery 显示文摘	Clark L C Lyons C Ann N Y	1962	Annals of the New York Academy of Science1962，102，1：	1
	5	Non-covalent functionalization of multi walled carbon nanotubes and their application for conductive composites显示文摘	Xu Li Siew Yee Wong Wuiwui Chauhari Tjiu Benjamin Paul Lyons Sue Ann Oh Chao Bin He	2008	Carbon2008，，5：	1
	6	Purification of Methyl Green using polyamide显示文摘	Anne Palle Andersen Palle Jakobsen Hans Lyon Poul Erik H?yer	1986	The Histochemical Journal1986，，8：	1
	7	Selectively Living in the Past:Nostalgia and Lifestyle显示文摘	Phil Lyon and Anne Colquhoun	1999	Consumer Studies&Home Economics1999，23，3：	1
	8	Chemically induced hypoxia by dimethyloxalylglycine(DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells显示文摘Inadequate vascularization leading to insufficient oxygen and nutrient supply in deeper layers of bioartificial tissues remains a limitation in current tissue engineering approaches to which prevascularization offers a promising solution.Hypoxia triggering pre-vascularization by enhanced vascular endothelial growth factor(VEGF)expression can be induced chemically by dimethyloxalylglycine(DMOG).Nanoporous silica nanoparticles(NPSNPs,or mesoporous silica nanoparticles,MSNs)enable sustained delivery of molecules and potentially release DMOG allowing a durable capillarization of a construct.Here we evaluated the effects of soluble DMOG and DMOG-loaded NPSNPs on VEGF secretion of adipose tissue-derived stem cells(ASC)and on tube formation by human umbilical vein endothelial cells(HUVEC)-ASC co-cultures.Repeated doses of 100 mM and 500 mM soluble DMOG on ASC resulted in 3-to 7-fold increased VEGF levels on day 9(P<0.0001).Same doses of DMOG-NPSNPs enhanced VEGF secretion 7.7-fold(P<0.0001)which could be maintained until day 12 with 500 mM DMOG-NPSNPs.In fibrin-based tube formation assays,100 mM DMOG-NPSNPs had inhibitory effects whereas 50 mM significantly increased tube length,area and number of junctions transiently for 4 days.Thus,DMOG-NPSNPs supported endothelial tube formation by upregulated VEGF secretion from ASC and thus display a promising tool for prevascularization of tissue-engineered constructs.Further studies will evaluate their effect in hydrogels under perfusion.	Sarah Zippusch Karen FWBesecke Florian Helms Melanie Klingenberg Anne Lyons Peter Behrens Axel Haverich Mathias Wilhelmi Nina Ehlert Ulrike Boer	2021	Regenerative Biomaterials2021，8，5：	0

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费