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| 1 | Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)显示文摘Beijing has been one of the epicenters attacked most severely by the SARS-CoV (severe acute respiratory syndrome-associated coronavirus) since the first patient was diagnosed in one of the city's hospitals. We now report complete genome sequences of the BJ Group, including four isolates (Isolates B J01, B J02, B J03,and B J04) of the SARS-CoV. It is remarkable that all members of the BJ Group share a common haplotype, consisting of seven loci that differentiate the group from other isolates published to date. Among 42 substitutions uniquely identifled from the BJ group, 32 are non-synonymous changes at the amino acid level.Rooted phylogenetic trees, proposed on the basis of haplotypes and other sequence variations of SARS-CoV isolates from Canada, USA, Singapore, and China, gave rise to different paradigms but positioned the BJ Group, together with the newly discovered GD01 (GD-Ins29) in the same clade, followed by the H-U Group (from Hong Kong to USA) and the H-T Group (from Hong Kong to Toronto), leaving the SP Group (Singapore) more distant. This result appears to suggest a possible transmission path from Guangdong to Beijing/Hong Kong, then to other countries and regions. | ShengliBi E‘deQin ZuyuanXu WeiLi JingWang YongWuHu YongLiu ShuminDuan JianfeiHu YujunHan JingXu YanLi YaoYi YongdongZhou WeiLin1 JieWen HongXu RuanLi ZizhangZhang HaiyanSun JinguiZhu ManYu BaochangFan QingfaWu WeiLin2 LinTang Bao’anYang GuoqingLi WenmingPeng WenjieLi TaoJiang YajunDeng BohuaLiu JianpingShi YongqiangDeng WeiWei HongLiu ZongzhongTong FengZhang YuZhang Cui‘eWang YuquanLi JiaYe YonghuaGan JiaJi XiaoyuLi XiangjunTian FushuangLu GangTan RuifuYang BinLiu SiqiLiu SonggangLi JunWang JianWang WuchunCao JunYu XiaopingDong HuanmingYang | 2003 | Genomics, Proteomics & Bioinformatics2003,1,3: | 1 |
| 2 | Light control of droplets on photo-induced charged surfaces显示文摘The manipulation of droplets plays a vital role in fundamental research and practical applications,from chemical reactions to bioanalysis.As an intriguing and active format,light control of droplets,typically induced by photochemistry,photomechanics,light-induced Marangoni effects or light-induced electric fields,enables remote and contactless control with remarkable spatial and temporal accuracy.However,current light control of droplets suffers from poor performance and limited reliability.Here we develop a new superamphiphobic material that integrates the dual merits of light and electric field by rationally preparing liquid metal particles/poly(vinylidene fluoride-trifluoroethylene)polymer composites with photo-induced charge generation capability in real time,enabling light control of droplets on the basis of photo-induced dielectrophoretic force.We demonstrate that this photo-induced charged surface(PICS)imparts a new paradigm for controllable droplet motion,including high average velocity(~35.9 mm s^(-1)),unlimited distance,multimode motions(e.g.forward,backward and rotation)and single-to-multiple droplet manipulation,which are otherwise unachievable in conventional strategies.We further extend light control of droplets to robotic and bio-applications,including transporting a solid cargo in a closed tube,crossing a tiny tunnel,avoiding obstacles,sensing the changing environment via naked-eye color shift,preparing hydrogel beads,transporting living cells and reliable biosensing.Our PICS not only provides insight into the development of new smart interface materials and microfluidics,but also brings new possibilities for chemical and biomedical applications. | Fang Wang Meijin Liu Cong Liu Chao Huang Lidong Zhang Anyang Cui Zhigao Hu Xuemin Du | 2023 | National Science Review2023,10,1: | 1 |
| 3 | Two-dimensional mesoporous sensing materials显示文摘Two-dimensional mesoporous materials combing ultrathin nanosheet morphology with well-defined mesoporous structures,are now emerging and becoming increasingly important for their promising applications in energy storage,electronic devices,electrocatalysts and so on.Here,we synthesized a kind of polypyrrole-based two-dimensional mesoporous materials with uniform pore size,ultrathin thickness and high surface area.Serving for electrochemical NH3 sensor,they exhibited a fast response and high sensitivity.Therefore,our study would promote much interest in design of new materials for gas sensor applications. | Yu Wen Facai Wei Wenqian Zhang Anyang Cui Jing Cui Chengbin Jing Zhigao Hu Qingguo He Jianwei Fu Shaohua Liu Jiangong Cheng | 2020 | Chinese Chemical Letters2020,31,2: | 0 |
| 4 | Design Theory of Intellectualized Computer Aided Instruction and Its Applications显示文摘This paper presents design theory and method of the intellectualized CAI, which includes the organization and expression of the teaching content and the teaching requirement determination in teaching process, and develops a highly intellectualized CAI software, LA-CAI, to use for liner arithmetic teaching program. | CUI Hong-bin 1, WANG Ai-min 2, YU Dong-mei 11.Hebei University of Science and Technology, Shijiazhuang 050054, China2.Anyang Teachers College, Anyang 455000, China | 2001 | Journal of Systems Science and Systems Engineering2001,13,2: | 0 |