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| 1 | Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals显示文摘AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals.METHODS Transient elastography with controlled attenuation parameter(CAP) was used to assess hepatic steatosis post-sustained virological response(SVR);the CAP technology was not available in the United States at study initiation.Liver stiffness/fibrosis was measured before and 47 wk after treatment completion.Patients with genotype 3 and patients with cirrhosis were excluded.RESULTS One hundred and one patients were included in the study.Post-SVR there were decreases from baseline in alanine aminotransferase(ALT)(63.1 to 17.8 U/L),aspartate aminotransferase(51.8 to 21.5 U/L) and fibrosis score(7.4 to 6.1 k Pa)(P < 0.05).Post-SVR,48 patients(47.5%) had steatosis on CAP;of these,6.25% had advanced fibrosis.Patients with steatosis had higher body mass index(29.0 vs 26.1 kg/m2),glucose(107.8 vs 96.6 mg/d L),ALT(20.4 vs 15.3 mg/d L),CAP score(296.3 vs 212.4 d B/m) and fibrosis score(7.0 vs 5.3 k Pa);P < 0.05.Interestingly,compared to baseline,both patients with and without steatosis had change in fibrosis score post-SVR(7.7 k Pa vs 7.0 k Pa and 7.0 k Pa vs 5.3 k Pa);alternatively,(P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness(≥ 7 k Pa).CONCLUSION Fatty liver is very common in hepatitis C virus(HCV) patients post-SVR.These patients continue to have elevated mean fibrosis score(≥ 7 k Pa) compared to those without fatty liver;some have advanced fibrosis.Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. | Mazen Noureddin Micaela M Wong Tsuyoshi Todo Shelly C Lu Arun J Sanyal Edward A Mena | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 2 | A technical review on nonalcoholic fatty liver disease显示文摘 | ARUN J SANYAL A G | 2002 | Gastroenterology2002，123，： | 1 |
| 3 | Tensile and elastic properties of tri-block copolymer based on aramide end-segments and po!yethermid- segments显示文摘 | Arun A Gaymans R J | 2009 | Journal of Applied Polymer Science2009，111，4： | 1 |
| 4 | Industrial ecology framework for achieving cleaner production in the mining and minerals industry 显示文摘 | Arun J B Dirk J A van Z | 2006 | Journal of Cleaner Production2006，，34： | 1 |
| 5 | Novel aluminium-silicon alloys for electronics packaging显示文摘 | Sangha S P S Jacobsom D M Arun J A | 1997 | Engineering Science and Education Journal1997，11，： | 1 |
| 6 | Genotype×environment interaction for zinc andiron concentration of wheat grain in eastern Gangetic plains of India显示文摘 | Joshi A K Crossa J Arun B | 2010 | Field Crops Research2010，116，： | 1 |
| 7 | Preventive therapy for breast cancer:a consensus statement显示文摘 | Cuzick J DeCensi A Arun B | 2011 | Lancet Oncol2011，12，： | 1 |
| 8 | Genotype×environment interaction for zinc and iron concentration of wheat grain in eastern Gangetic Plains of India显示文摘 | Joshi A K Crossa J Arun B | 2010 | Field Crop Res2010，116，： | 1 |
| 9 | Preventive therapy for breast cancer:a consensus statement显示文摘 | Cuzick J DeCensi A Arun B | | 0，，05： | 1 |
| 10 | Genotype X environment interaction for zinc and iron concentration of wheat grain in eastern Gangetic plains of India显示文摘 | Joshi A K Crossa J Arun B | 2010 | Field Crops Research2010，116，： | 1 |
| 11 | Modelling capillary flow in complex geometries 显示文摘 | DILIP R ARUN P A MARCHAL J M | 2001 | Text Res J2001，71，： | 1 |
| 12 | FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles显示文摘The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies.Over the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats.Yet,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging.In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels.Combining the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,respectively.This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental stud-ies.In order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences.On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2020 | Fungal Diversity2020，，6： | 1 |
| 13 | High prevalence of preinvasive lesions adjacent to BRCA1/2 - associated breast cancers 显示文摘 | Arun B Vogel K J Lopez A | 2009 | Cancer Prev Res (Phila)2009，2，2： | 1 |
| 14 | Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis显示文摘 | Michelle N Sicard Clement C Zai Arun K Tiwari Renan P Souza Herbert Y Meltzer Jeffrey A Lieberman James L Kennedy Daniel J Mü ller | 2010 | Pharmacogenomics2010，，11： | 1 |
| 15 | Tensile and eiastie proPerties of tri-block copolymer based on aramide end-segmenis and polyether mid-segments 显示文摘 | A ARUN R J GAYMANS | 2009 | Journal of Applied polymer Scieene2009，111，4： | 1 |
| 16 | Preventive therapy for breast can cer:a consensus statement显示文摘 | Cuzik J DeCensi A Arun B | 2011 | Lancet Oncol2011，12，5： | 1 |
| 17 | sphincter saving technique for fistula-in-ano the ligation of intersphincteric fistula tract 显示文摘 | Rojanasakul A pattana??arun J Sahakitrun- gruang C total anal | 2007 | Med A sso Thai2007，90，： | 1 |
| 18 | Industrial ecology framework for achieving cleaner production in the mining and minerals in- dustry 显示文摘 | Arun J Basu Dirk J A van Zyl | 2006 | Journal of Cleaner Production2006，14，2： | 1 |
| 19 | Selenium-an antioxidative protectant in soybean during senescence显示文摘 | Djanaguiraman M Devi D D Shanker Arun K Sheeba J A Bangarusamy U | 2005 | Plant Soil2005，272，1： | 1 |
| 20 | Nonalcoholic fatty liver disease in patients with hepatitis C is associated with features of the metabolic syndrome显示文摘 | Arun J Sanyal Melissa J Contos Richard K Sterling Velimir A Luketic Mitchell L Shiffman R.Todd Stravitz A.Scott Mills | 2003 | The American Journal of Gastroenterology2003，，9： | 1 |
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