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| 1 | Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg显示文摘Self-healing coatings have been developed as smart surface coatings for Mg and its alloys to retain local corrosion from the coating damages.In this study,we prepared dicalcium phosphate dihydrate(DCPD)coating on biomedical Mg,and found that the artificial scratches in DCPD coating can be efficiently sealed by anti-corrosive products in both Hank's and normal saline(NS)solutions.Besides,the in-depth study revealed that DCPD was served as not only a physical barrier but also a self-healing agent,demonstrating an autonomous self-healing coating without embedded extra corrosion inhibitors.Moreover,Hank's solution provided foreign-aid filmforming ions to promote self-healing behavior.The findings might offer new opportunities for further studies and applications of efficient self-healing coatings on biodegradable Mg implants. | Qiangsheng Dong Xingxing Zhou Yuanjia Feng Kun Qian Huan Liu Mengmeng Lu Chenglin Chu Feng Xue Jing Bai | 2021 | Bioactive Materials2021，6，1： | 4 |
| 2 | Preparation, microstructure and degradation performance of biomedical magnesium alloy fine wires显示文摘With the development of new biodegradable Mg alloy implant devices, the potential applications of biomedical Mg alloy fine wires are realized and explored gradually. In this study, we prepared three kinds of Mg alloy fine wires containing 4 wt% RE(Gd/Y/Nd) and 0.4 wt% Zn with the diameter less than 0.4 μm through casting, hot extruding and multi-pass cold drawing combined with intermediated annealing process. Their microstructures, mechanical and degradation properties were investigated. In comparison with the corresponding as-extruded alloy, the final fine wire has significantly refined grain with an average size of 3–4 μm, and meanwhile shows higher yield strength but lower ductility at room temperature. The degradation tests results and surface morphologies observations indicate that Mg–4Gd–0.4Zn and Mg–4Nd–0.4Zn fine wires have similar good corrosion resistance and the uniform corrosion behavior in SBF solution. By contrast, Mg–4Y–0.4Zn fine wire shows a poor corrosion resistance and the pitting corrosion behavior. | Jing Bai Lingling Yin Ye Lu Yiwei Gan Feng Xue Chenglin Chu Jingli Yan Kai Yan Xiaofeng Wan Zhejun Tang | 2014 | Progress in Natural Science:Materials International2014，24，5： | 3 |
| 3 | The effect of enzymes on the in vitro degradation behavior of Mg alloy wires in simulated gastric fluid and intestinal fluid显示文摘With an upsurge of biodegradable metal implants,the research and application of Mg alloys in the gastrointestinal environment of the digestive tract have been of great interest.Digestive enzymes,mainly pepsin in the stomach and pancreatin in the small intestine,are widespread in the gastrointestinal tract,but their effect on the degradation of Mg alloys has not been well understood.In this study,we investigated the impacts of pepsin and pancreatin on the degradation of Mg-2Zn alloy wires.The results showed that the pepsin and pancreatin had completely different even the opposite effects on the degradation of Mg,although they both affected the degradation product layer.The degradation rate of Mg wire declined with the addition of pepsin in simulated gastric fluid(SGF)but rose with the addition of pancreatin in simulated intestinal fluid(SIF).The opposite trends in degradation rate also resulted in completely different degradation morphologies in wires surface,where the pitting corrosion in SGF was inhibited because of the physical barrier effect of pepsin adsorption.In contrast,the adsorption of pancreatin affected the integrity of magnesium hydrogen phosphate film,causing a relatively uneven degraded surface.These results may help us to understand the role of different digestive enzymes in the degradation of magnesium and facilitate the development and clinical application of magnesium alloy implanted devices for the digestive tract. | Yue Zhang Jian Cao Xianli Wang Huan Liu Yi Shao Chenglin Chu Feng Xue Jing Bai | 2022 | Bioactive Materials2022，7，1： | 2 |
| 4 | 3D-cubic interconnected porous Mg-based scaffolds for bone repair显示文摘Mg-based porous materials,as potential bone tissue engineering scaffolds,are considered an attractive strategy for bone repair owing to favorable biodegradability,good biocompatibility and suitable mechanical properties.In this work,3D-cubic interconnected porous Mg–xZn–0.3Ca(x=0,3,6)scaffolds were prepared to obtain desirable pore structures with a mean porosity up to 73%and main pore size of 400–500μm,which pore structures were close to the human cancellous bone.The structure–property relationships in the present scaffolds were analyzed by experiments and theoretical models of generalized method of cells(GMC).Mg–xZn–0.3Ca scaffolds exhibited good compression properties with a maximum above 5MPa in yield strength and about 0.4GPa in elastic modulus.This was attributed to not only the alloy strengthening but also the large minimum solid area.On the other hand,the scaffolds showed undesirable and relatively serious degradation behavior in Hank’s solution,resulting from Zn addition in Mg-based scaffolds and the high surface area ratio in the pore structure.Therefore,surface modifications are worth studying for controlled degradation in the future.In conclusion,this research would explore a novel attempt to introduce 3D-cubic pore structure for Mg-based scaffolds,and provide new insights into the preparations of Mg-based scaffolds with good service performances for bone repair. | Qiangsheng Dong Yang Li Huiqin Jiang Xingxing Zhou Huan Liu Mengmeng Lu Chenglin Chu Feng Xue Jing Bai | 2021 | Journal of Magnesium and Alloys2021，9，4： | 2 |
| 5 | Dehydrogenation of long chain paraffins over supported Pt-Sn-K/AI2 03 catalysts: a study of the alumina support effect显示文摘 | He Songbo Sun Chenglin Bai Ziwu | 2009 | Applied Catalysis A: General2009，365，： | 1 |
| 6 | Dehydrogenation of long chain paraffins over supported Pt-Sn-K/AUOa catalysts; A study of the alumina support effect显示文摘 | He Songbo? Sun Chenglin Bai Ziwu | 2009 | Appl Catal A2009，356，1： | 1 |
| 7 | Compacton, peakon and folded localized excitatios for the (2-4-1)-dimentional Broer-Kaup system 显示文摘 | Bai Chenglin Zhon Hong | 2005 | Chaos Solitons and Fractals2005，23，： | 1 |
| 8 | Food safety assurance systems in China显示文摘 | Li Bai Chenglin Ma Shunlong Gong Yinsheng Yang | 2007 | Food Control2007，，18： | 1 |
| 9 | Multiple soliton solutions of the high order Broer-Kaup equations显示文摘 | Bai Chenglin | 2000 | Communications in Theoretical Physics2000，34，4： | 1 |
| 10 | Dehydrogenation of long chain paraffns over supported Pt--Sn--K/AI203 catalysts: A study of the alumina support effect显示文摘 | He Songbo Sun Chenglin Bai Ziwu | 2009 | Applied catalysis A : General2009，356，： | 1 |
| 11 | Impact behaviors of poly-lactic acid based biocomposite reinforced with unidirectional high-strength magnesium alloy wires显示文摘A novel poly-lactic acid(PLA) based biocomposite reinforced with unidirectional high-strength magnesium alloy(Mg-alloy) wires for bone fracture fixation was fabricated by hot-compressing process. The macroscopical and microscopical impact behaviors of the biocomposite were investigated using impact experiments and finite element method(FEM), respectively. The results indicated that the biocomposite had favorable impact properties due to the plastic deformation behavior of Mg-alloy wires during impact process. While the content of Mg-alloy wires reached20 vol%, the impact strength of the composite could achieve 93.4 k J/m2, which is approximate 16 times larger than that of pure PLA fabricated by the same process. According to FEM simulation results, the complete destruction life of the composites during impact process increased with increasing volume fraction of Mg-alloy wires, indicating a high impact-bearing ability of the composite for bone fracture fixation.Simultaneously, the energy absorbed by Mg-alloy wires in the composites had a corresponding increase. In addition, it denoted that the impact properties of the composites are sensitive to the initial properties of the matrix material. | Xuan Li Chao Guo Xiaokai Liu Lei Liu Jing Bai Feng Xue Pinghua Lin Chenglin Chu | 2014 | Progress in Natural Science:Materials International2014，24，5： | 1 |
| 12 | Food safety assurance systems in China显示文摘 | Li Bai Chenglin Ma Shunlong Gong Yinsheng Yang | 2006 | Food Control2006，，5： | 1 |
| 13 | Dehydrogenation of long chain paraffins over supported Pt-Sn-K/A1203 catalysts: A study of the alumina support effect显示文摘 | Songbo He Chenglin Sun Ziwu Bai | 2009 | Applied Catalysis A: General2009，356，： | 1 |
| 14 | THE DESIGN AND IMPLEMENTATION ON THE NETWORK ENVIRONMENT OF THE MULTIMEDIA INFORMATION PROCESSING SYSTEM显示文摘The Multimedia Information Processing System(MMIPS)is an distributed & integrated system to combine the voice, images, graphics, and text information processing technology in an organic whole and to coordinate the whole processing functions. The research on the system network environments of the MMIPS play a very important part in that whether the all sorts media of MMIPS can present automatically,effectively,coordinately and comprehensively in front of users or | Bai Chenglin(The Optical Communication Institute) | 1997 | 聊城大学学报(自然科学版)1997，15，4： | 1 |
| 15 | Dehydrogenation of longchain paraffins over supported Pt-Sn-K/Al2 03 catalysts : astudy of the alumina support effect显示文摘 | He Songbo Sun Chenglin Bai Ziwu | 2009 | Applied Catalysis A:General2009，，： | 1 |
| 16 | Characterization of coke deposited on spent catalysts for long-chain-paraffin dehydrogenation显示文摘 | Songbo He Chenglin Sun Xu Yang Bin Wang Xihai Dai Ziwu Bai | 2010 | Chemical Engineering Journal2010，，3： | 1 |
| 17 | Dehydrogenation of long chain paraffins over supported Pt-Sn-K/A12O3 cata- lysts: a study of the alumina support effect 显示文摘 | He Songbo Sun Chenglin Bai Ziwu | 2009 | Applied Catalysis A: General2009，356，1： | 1 |
| 18 | A New Generalized Algebraic Method and Its Application in Nonlinear Evo- lution Equations with Variable Coefficients 显示文摘 | BAI Chenglin BAI Chengjie ZHAO Hong | 2005 | Naturforsch2005，60，： | 1 |
| 19 | The influence of alternating cyclic dynamic loads with different low frequencies on the bio-corrosion behaviors of AZ31B magnesium alloy in vitro显示文摘The real physiological environment of human body is complicated with different degrees and forms of dynamic loads applied to implanted medical devices due to the daily activities of the patients,which would have impacts on the degradation behaviors of magnesium alloy implants.In this work,the bio-corrosion behaviors of AZ31B magnesium alloy under alternating cyclic dynamic loads with different low frequencies(0.1-2.5 Hz)were specially investigated.It was found that the bio-degradation performances under external dynamic stressed conditions were much severer than those under unstressed conditions and static loads.The corrosion rates were generally accelerated as the rise of cyclic frequency.Hereby a numerical model for the degradation process of Mg alloy was established.The corrosion current density icorr of Mg alloy and the applied loading frequency f matches a linear relationship of ln icorr∝f,which is the result of interactions between the cyclic alternating load and corrosive environment.This work could provide a theoretical reference and an experimental basis for further researches on the biodegradation behaviors of biomedical materials under dynamic conditions. | Linyuan Han Zhenwei Zhang Jianwei Dai Xuan Li Jing Bai Zhihai Huang Chao Guo Feng Xue Chenglin Chu | 2022 | Bioactive Materials2022，7，1： | 0 |
| 20 | A biodegradable magnesium surgical staple for colonic anastomosis: In vitro and in vivo evaluation显示文摘Staplers have been widely used in the clinical treatment of gastrointestinal reconstruction.However,the current titanium(Ti)staple will remain in the human body permanently,resulting in some adverse effects.In this study,we developed a type of biodegradable staple for colonic anastomosis using 0.3 mm diameter magnesium(Mg)alloy wires.The wire surface was modified by micro-arc oxidation treatment(MAO)and then coated with poly-L-lactic acid(PLLA)to achieve a moderate degradation rate matching the tissue healing process.The results of tensile tests on isolated porcine colon tissue anastomosed by Mg and Ti staples showed that the anastomotic property of Mg staples was almost equal to that of Ti staples.The in vitro degradation tests indicated the dual-layer coating effectively enhanced the corrosion resistance and maintained the tensile force of the coated staple stable after 14-day immersion in the simulated colonic fluid(SCF).Furthermore,24 beagle dogs were employed to conduct a comparison experiment using Mg-based and clinical Ti staples for 90-day implantation by ent-to-side anastomosis of the colon.The integrated structure of Mg-based staples was observed after 7 days and completely degraded after 90 days.All animals did not have anastomotic leakage and stenosis,and 12 dogs with Mg-based staples fully recovered after 90 days without differences in visceral ion levels and other side effects.The favorable performance makes this Mg-based anastomotic staple an ideal candidate for colon reconstruction. | Yue Zhang Jian Cao Mengmeng Lu Yi Shao Kewei Jiang Xiaodong Yang Xiaoyu Xiong Shan Wang Chenglin Chu Feng Xue Yingjiang Ye Jing Bai | 2023 | Bioactive Materials2023，，4： | 0 |
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