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| 1 | Polymorphisms in NF-κB,PXR,LXR,PPARγ and risk of inflammatory bowel disease显示文摘AIM:To investigate the contribution of polymorphisms in nuclear receptors to risk of inflammatory bowel disease(IBD) . METHODS:Genotypes of nuclear factor(NF) -κB(NFKB1) NFκB-94ins/del(rs28362491) ;peroxisome proliferatoractivated receptor(PPAR) -γ(PPARγ) PPARγPro12Ala(rs1801282) and C1431T(rs 3856806) ;pregnane X receptor(PXR) (NR1I2) PXR A-24381C(rs1523127) ,C8055T(2276707) ,and A7635G(rs 6785049) ;and liver X receptor(LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients,495 ulcerative colitis(UC) patients,and 779 healthy controls.Odds ratio(OR) and 95%CI were estimated by logistic regression models. RESULTS:The PXR A7635G variant,the PPARγPro12Ala and LXR T-rs2695121-C homozygous variant genotypes were associated with risk of UC(OR:1.31,95% CI:1.03-1.66,P=0.03,OR:2.30,95%CI:1.04-5.08,P=0.04,and OR:1.41,95%CI:1.00-1.98,P=0.05,respectively) compared to the corresponding homozygous wild-type genotypes.Among never smokers,PXR A7635G and the LXR T-rs1405655-C and T-rs2695121-C variant genotypes were associated with risk of IBD(OR:1.41,95%CI:1.05-1.91,P=0.02,OR:1.63,95%CI:1.21-2.20,P=0.001,and OR:2.02,95%CI:1.36-2.99,P=0.0005,respectively) compared to the respective homozygous variant genotypes.PXR A7635G(rs6785049) variant genotype was associated with a higher risk of UC diagnosis before the age of 40 years and with a higher risk of extensive disease(OR:1.34,95%CI:1.03-1.75 and OR:2.49,95%CI:1.24-5.03,respectively) . CONCLUSION:Common PXR and LXR polymorphisms may contribute to risk of IBD,especially among never smokers. | Vibeke Andersen Jane Christensen Anja Ernst Bent A Jacobsen Anne Tjφnneland Henrik B Krarup Ulla Vogel | 2011 | World Journal of Gastroenterology2011，17，2： | 4 |
| 2 | 快速凝固富钛Ti-V合金的微观组织和储氢性能(英文)显示文摘研究目的在于优化Ti0.8-0.9V0.2-0.1二元合金的相结构成分、微观组织和储氢性能。该合金主要用于从含有大量一氧化碳的高温气态混合物中吸收氢气。Ti0.8-0.9V0.2-0.1合金中的α-(HCP)和β-(BCC)相在纯氢气中基于氢化作用,形成单相FCC结构的氢化物,此过程与合金的化学成分无关。同步辐射X射线衍射的原位分析表明,在含有氢气和10%一氧化碳的混合气体中,只有β相转变成相应的氢化物。快速凝固(RS)处理细化了Ti0.8V0.2和Ti0.9V0.1合金的晶粒组织,而且,快速凝固处理增加了Ti0.9V0.1合金中的β相,其所占比例是普通熔铸条件下的两倍。扫描电子显微镜(SEM)分析表明,Ti0.9V0.1合金含有片状组织,层片的厚度约为300nm。热脱附谱(TDS)显示,微观组织的细化可以加快氢脱附的动力学过程。 | Suwarno SUWARNO Jan Ketil SOLBERG Jan Petter MAEHLEN Bente KROGH Bφrre Tore BφRRESEN Esther OCHOA-FERNANDEZ Erling RYTTER Mario WILLIAMS Roman DENYS Volodymyr A.YARTYS | 2012 | Transactions of Nonferrous Metals Society of China2012，22，8： | 2 |
| 3 | Insulin-like factor-Ⅰ gene therapy applications for cartilage repair 显示文摘 | Nixon AJ Toland B Bent SJ | 2000 | Clin Orthop Relat Res2000，379，： | 1 |
| 4 | Gene mediated insulin-like growth factor-I delivery to the synovium显示文摘 | SAXER R A BENT S J BROWE-TOLAND B D | 2001 | J Orthop Res2001，19，5： | 1 |
| 5 | Insulinlike growth factor-1 gene therapy applications for cartilage repair 显示文摘 | Nixon A J Brower-Toland B D Bent S J | 2000 | Clin Orthop2000，，： | 1 |
| 6 | Animal-assisted therapy with farm animals -for persons with psychiairic disorders: effects on self-ef- ficacy, coping ability and quality of life, a randomized controlled trial显示文摘 | Bente B Oivind E Bjarne OB | 2008 | Clinical Practice and Epidemiology in Mental Health2008，4，1： | 1 |
| 7 | Buffer zones and constructed wetlands as filters for agricultural phosphorus显示文摘 | JAANA U K BENT B HAKAN J | 2000 | Journal Environmental Quality2000，29，： | 1 |
| 8 | Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle–mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response显示文摘 | Ivan Grskovic Anna Kutsch Christian Frie Gergely Groma Jacek Stermann Ursula Schl?tzer‐Schrehardt Anja Niehoff Stephen E Moss Sabrina Rosenbaum Ernst P?schl Markus Chmielewski Gunter Rappl Hinrich Abken John F Bateman Kathryn SE Cheah Mats Paulsson Bent B | 2012 | J Bone Miner Res2012，，11： | 1 |
| 9 | RPS2 of Arabidopsis thaliana: A leucine-fich repeat class of plant disease resistance genes 显示文摘 | Bent A F Kunkel B N Dahlbeck D | 1994 | Science1994，，265： | 1 |
| 10 | Differential changes in ser- um uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial显示文摘 | Charlotte A Peter W Bente B | 2009 | Nutrition Metabolism2009，6，42： | 1 |
| 11 | Perivascular cells expressing annexin A5 define a novel mesenchymal stem cell-like population with the capacity to differentiate into multiple mesenchymal lineages显示文摘 | Bent B Helga M Friederike P | 2005 | Development2005，132，11： | 1 |
| 12 | RPS2 of Ar- abidopsis thaliana:a leucine - rich repeat class of plant disease resistance genes 显示文摘 | Bent A F Kunkel B N Dahlbeck D | 1994 | Science1994，265，5180： | 1 |
| 13 | Vaccination of mice with plasmids expressing processed capsid protein of foot-and-mouth disease virus-Importance of dominant and subdominant epitopes for antigenicity and protection 显示文摘 | Tine H F Annette M B Bent A | 2007 | Vaccine2007，25，： | 1 |
| 14 | Microstructure-dependent nuclea- tion in atomic layer deposition of Pt on TiO2 显示文摘 | LEE H B R BENT S F | 2012 | Chem Ma- ter2012，24，2： | 1 |
| 15 | Are veterinary medicines causing environmental risks显示文摘 | Alistairb A B Danaw K Bent H | 2003 | Environmental Science and Technology2003，1，： | 1 |
| 16 | Overview on Macro Fiber Composite Applications显示文摘 | Andreas J S Thomas D Bent B | 2006 | Proceeding of SPIE2006，6170，： | 1 |
| 17 | QT dispersion has no prognostic information of patients with advanced congestive heart failure and reduced left ventricular systolie显示文摘 | Bente B Hanne E Li J | 2001 | Circulation2001，103，： | 1 |
| 18 | Over-expression of cytochrome P450 CYP6CM1 is associated with high resistance to imidacloprid in the B and Q biotypes ofBemisia tabaci (Hemiptera: Aleyrodidae)显示文摘 | Karunker I Benting J Lueke B | 2008 | Insect Biochemistry and Molecular Biology2008，38，5： | 1 |
| 19 | Atherosclerotic Plaque Stability--What Determines the Fate of a Plaque显示文摘 | Bente Halvorsen Kari Otterdal Tuva B | 2008 | Pro- gress in Cardiovascular Diseases2008，51，3： | 1 |
| 20 | Over-expression of cytochrome P450 CYP6CMI is associated with high re- sistance to imidacloprid in the B and Q biotypes of Be- misia tabaci (Hemiptera:Aleyrodidae) 显示文摘 | Karunker I Benting J Lueke B | 2008 | Insect Bio- chemistry and Molecular Biology2008，38，6： | 1 |
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