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| 1 | Brain-gut axis in the pathogenesis of Helicobacter pylori infection显示文摘Helicobacter pylori(H.pylori)infection is the main pathogenic factor for upper digestive tract organic diseases.In addition to direct cytotoxic and proinflammatory effects,H.pylori infection may also induce abnormalities indirectly by affecting the brain-gut axis,similar to other microorganisms present in the alimentary tract.The brain-gut axis integrates the central,peripheral,enteric and autonomic nervous systems,as well as the endocrine and immunological systems,with gastrointestinal functions and environmental stimuli,including gastric and intestinal microbiota.The bidirectional relationship between H.pylori infection and the brain-gut axis influences both the contagion process and the host’s neuroendocrine-immunological reaction to it,resulting in alterations in cognitive functions,food intake and appetite,immunological response,and modification of symptom sensitivity thresholds.Furthermore,disturbances in the upper and lower digestive tract permeability,motility and secretion can occur,mainly as a form of irritable bowel syndrome.Many of these abnormalities disappear following H.pylori eradication.H.pylori may have direct neurotoxic effects that lead to alteration of the brain-gut axis through the activation of neurogenic inflammatory processes,or by microelement deficiency secondary to functional and morphological changes in the digestive tract.In digestive tissue,H.pylori can alter signaling in the brain-gut axis by mast cells,the main brain-gut axis effector,as H.pylori infection is associated with decreased mast cell infiltration in the digestive tract.Nevertheless,unequivocal data concerning the direct and immediate effect of H.pylori infection on the brain-gut axis are still lacking.Therefore,further studies evaluating the clinical importance of these host-bacteria interactions will improve our understanding of H.pylori infection pathophysiology and suggest new therapeutic approaches. | Jacek Budzyński Maria Kopocka | 2014 | World Journal of Gastroenterology2014,20,18: | 29 |
| 2 | Systemic therapy for cervical carcinoma–current status显示文摘Two major treatment modalities in cervical cancer are radiation therapy(RT) and surgery. Chemotherapy continues to be the main form of systemic therapy adjunctive to definitive local therapies, and is used for palliation.Platinum-based regimens, administered concurrently with both definitive and postoperative RT, were demonstrated to provide significant survival benefits, whereas the beneficial effect of concurrent chemoradiotherapy in later-stage disease was smaller. The role of chemotherapy in addition to RT in IB1/IIA1 cervical cancer patients not undergoing surgery remains undefined. Likewise, the role of chemotherapy in combination with postoperative RT for patients with intermediate-risk factors for recurrence has not yet been verified. The recent standard for chemoradiotherapy is cisplatin alone administered weekly. Other cisplatin-based or non-cisplatin-based regimens have not been subjected to large clinical studies. The benefits of consolidation chemotherapy after chemoradiation for locally advanced cervical cancer are still undetermined. Neoadjuvant cisplatin-based chemotherapy followed by surgery has shown survival benefits, however its role in the era of chemoradiotherapy remains unclear. The combination of cisplatin and paclitaxel is considered a standard regimen in the palliative setting. There is no standard of care for second-line systemic therapy in advanced cervical cancer.Bevacizumab combined with palliative chemotherapy(cisplatin/paclitaxel or topotecan/paclitaxel) in the first-line treatment for recurrent/metastatic cervical cancer significantly improves overall survival when compared to chemotherapy alone. The role of immunotherapy in cervical cancer remains to be established. The optimal combined modality treatment including systemic therapy for cervical tumors of non-squamous histology remains a matter of debate. Ongoing accumulation of data on genomic and proteomic characteristics provides insight into the molecular heterogeneity of cervical cancer and paves the way for developing molecularly targeted therapies. | Krystyna Serkies Jacek Jassem | 2018 | Chinese Journal of Cancer Research2018,30,2: | 26 |
| 3 | 新能源电动汽车异种材料连接技术的挑战、趋势和进展显示文摘多材料混合结构在车身上的应用可以实现汽车安全性、轻量化水平的共同提升,也是如今新能源汽车工业发展的一个主要方向。先进高强钢(Advanced high strength steel,AHSS)、铝合金、工程塑料以及碳纤维增强复合材料(Carbon fiber reinforced polymer,CFRP)等作为轻质高强材料的代表已广泛应用于白车身、覆盖件以及复杂结构件的制造中。 | 李红 刘旭升 张宜生 Jacek Senkara 李光瀛 马鸣图 | 2019 | 材料导报2019,33,23: | 18 |
| 4 | Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases显示文摘BACKGROUND: There is a growing evidence that matrix metalloproteinase (MMP)-2 and MMP-9 (gelatinases) play an important role in the pathogenesis of numerous disorders especially with inflammatory etiology and extracellular matrix (ECM) remodeling. Despite the fact that gelatinases involve in liver cirrhosis is provided in the literature, their role in the pathogenesis of chronic pancreatitis and non-specific inflammatory bowel diseases is still under investigation.DATA SOURCES: We carried out a PubM ed search of English language articles relevant to the involvement of gelatinases in the pathogenesis of liver fibrosis, pancreatitis, and non-specific inflammatory bowel diseases.RESULTS: The decreased activity of gelatinases, especially MMP-2, is related to the development of liver fibrosis, probably due to the decrease of capability for ECM remodeling. Similar situation can be found in chronic pancreatitis; however reports on this matter are rare. The presence of non-specific inflammatory bowel diseases results in MMP-9 activity elevation.CONCLUSION: The fluctuation of gelatinases activity during liver fibrosis, chronic pancreatitis and non-specific inflammatorybowel diseases is observed, but the exact role of these enzymes demands further studies. | Jacek Kurzepa Agnieszka M?dro Gra?yna Czechowska Joanna Kurzepa Krzysztof Celiński Weronika Kazmierak Maria S?omka | 2014 | Hepatobiliary & Pancreatic Diseases International2014,13,6: | 15 |
| 5 | Blood Serum Levels of IL-2, IL-6, IL-8, TNF-α and IL-1β in Patients on Maintenance Hemodialysis显示文摘Cytokines 是有免疫力的反应和煽动性的反应的必要调停人。有长期的肾的失败(CRF ) 的病人通常与除了 dialyzer 膜的 bioincompatibility 与损害的肾功能和尿毒症的毒素的累积联系的有免疫力的功能的畸形介绍。在 hemodialysis (HD ) 期间会议, cytokines 主要被内毒素类型混合物在有 dialyzer 的 dialyzer 液体,补充因素和直接接触激活的单核白血球释放膜。学习包括了 15 个 CRF 病人, 36.4 吗?? | Jacek Rysz Maciej Banach Aleksandra Cialkowska-Rysz Robert Stolarek Marcin Barylski Jaroslaw Drozdz Piotr Okonski | 2006 | Cellular & Molecular Immunology2006,3,2: | 14 |
| 6 | Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25显示文摘堵住抗体 ipilimumab 的细胞毒素的 T 淋巴细胞 antigen-4 (CTLA-4 ) 在很少的病人导致变形黑瘤的调停免疫者的长期的控制。尽管 ipilimumab 无疑经由 immunostimulation 施加它的治疗学的效果,这样远的临床上有用的、 immunologically 相关的 biomarkers 预言治疗效率是逃犯的。这里,我们显示出 IL-2 的那中立化或堵住 α并且 βIL-2 受体的子单元(CD25 和 CD122,分别地) 否则在现出症状之前的潜的老鼠模型由 CTLA-4 封锁导致了,废除了 antitumor 效果和 intratumoral T 受动器对规章的房间(Tregs ) 的比率的伴随的改进,它是。CTLA-4 封锁导致了在失去了 FoxP3 表示并且在 regressing 肿瘤积累了的 IL-2-producing 受动器房间与伴随物上升表示 Lag3, ICOS, IL-10 和 Egr2 的一个镇压 CD4 + T 房间子集的减小。当 recombinant IL-2 改进了 CTLA-4 封锁的治疗学的功效时,圈套 IL-2 受体 α(IL-2Rα, sCD25 ) 禁止了 CTLA-4 的 anticancer 效果封锁。在收到 ipilimumab 的 262 个变形黑瘤病人, sCD25 的基线浆液集中代表了全面幸存的独立指示物,与预言到治疗的抵抗的高水平。总的来说,这些结果解开为在 CTLA-4 的 anticancer 活动的 IL-2 和 IL-2 受体的一个角色封锁。重要地,我们的学习提供第一 immunologically 相关的 biomarker,也就是提高的浆液 sCD25,那与黑瘤在病人预言抵抗到 CTLA-4 封锁。 | Dalil Hannani Marie Vetizou David Enot Sylvie Rusakiewicz Nathalie Chaput David Klatzmann Melanie Desbois Nicolas Jacquelot Nadege Vimond Salem Chouaib Christine Mateus James P Allison Antoni Ribas Jedd D Wolchok Jianda Yuan Philip Wong Michael Postow Andrzej Mackiewicz Jacek Mackiewicz Dirk Schadendorff Dirk Jaeger Alan J Korman Keith Bahjat Michele Maio Luana Calabro Michele WL Teng Mark J Smyth Alexander Eggennont Caroline Robert Guido Kroemer Laurence Zitvogel | 2015 | Cell Research2015,25,2: | 14 |
| 7 | Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis显示文摘Sphingolipids 被建议了在植物房间为一连串的细胞的发信号活动充当第二个送信人,包括压力回答并且规划了房间死亡(PCD ) 。然而,这些过程不是的机制 underpinning 很好理解。这里,我们报导那 Arabidopsis 异种, fumonisin B1 抵抗 11-1 ( fbr 11-1 )没能产生反应的氧中介( ROI ),不能当异种被 fumonisin B ( 1 )( FB ( 1 ))质问时,开始 PCD , ceramide synthase 的一个特定的禁止者。显示的分子的分析 FBR11 编码一个长链的底 1 (LCB1 ) 丝氨酸 palmitoyltransferase (SPT ) 的子单元,它催化 de novo sphingolipid 的第一限制率的步合成。sphingolipid 集中的集体度谱的分析表明而 fbr 11-1 变化没影响 sphingoid 底的基础层次,异种响应 FB (1 ) 显示出 sphingoid 底的稀释形成。由一个直接的喂实验,我们证明免费 sphingoid 底 dihydrosphingosine, phytosphingosine 和鞘氨醇高效地导致产生由房间死亡跟随了的 ROI。相反地, dihydrosphingosine 导致的 ROI 产生和房间死亡被它的 phosphorylated 形式 dihydrosphingosine-1-phosphate 明确地以一种剂量依赖者方式堵住,建议在一个免费 sphingoid 底和它的 phosphorylated 衍生物之间的动态平衡的维护对决定房间命运批评。因为 sphingolipid 水平的改变发生在 ROI 生产以前,我们建议免费 sphingoid 库在 Arabidopsis 涉及 PCD 的控制,大概在收到不同发展或环境的暗示之上通过 ROI 的规定铺平。 | Lihua Shi Jacek Bielawski Jinye Mu Haili Dong Chong Teng Jian Zhang Xiaohui Yang Nario Tomishige Kentaro Hanada Yusuf A Hannun Jianru Zuo | 2007 | Cell Research2007,17,12: | 12 |
| 8 | Heterotopic pancreatic tissue in the gastric cardia: A case report and literature review显示文摘The heterotopic pancreas, which is usually described as an untypical presence of pancreatic tissue without any anatomic or vascular continuity with the pancreas, is relatively rare. Clinical manifestations may include bleeding, inflammation, pain and obstruction; however, in most cases it remains silent and is diagnosed during autopsy. Here, we report a case of ectopic pancreatic lesion located in the gastric cardia. The patient was a 73-year-old woman who had a history(over four months) of chronic epigastric pain accompanied by heartburn. Esophagogastroduodenoscopy revealed inflammatory changes throughout the stomach and lower esophagus, as well as a flat polypoid mass with benign features located in the gastric cardia, approx. 10 mm below the 'Z' line, measuring approx. 7 mm in diameter. Endoscopic biopsy forceps were used to remove the lesion. Histological examination of the lesion revealed the presence of heterotopic pancreatic tissue in the gastric mucosa. On the basis of the presented case, we suggest that pancreatic ectopia should be a part of differential diagnosis, not only when dealing with submucosal gastric lesions, but also with those that are small, flat and/or untypically located. | Rafa? Filip Ewa Walczak Jacek Huk Rados?aw P Radzki Marek Bieńko | 2014 | World Journal of Gastroenterology2014,20,44: | 12 |
| 9 | Small bowel tumors detected and missed during capsule endoscopy: Single center experience显示文摘AIM:To characterize small bowel(SB)tumors detected by capsule endoscopy(CE),and identify missed tumors.METHODS:The study included 145 consecutive patients in whom 150 CEs were performed.Following CE,the medical records of the study population were reviewed.Results of double-or single-balloon enteroscopy performed after CE and the results of surgery in all patients operated on were retrieved.The patients were contacted through telephone interviews or postal mail.In addition,the national cancer registry and the polish clinical gastrointestinal stromal tumor(GIST)Registry were searched to identify missed neoplasms.RESULTS:Indications for CE included overt and occult obscure gastrointestinal bleeding(n=81,53.7%),anemia(n=19,12.7%),malabsorption(n=18,12%),abnormal CB follow through(n=9,6%),abdominal pain(n=7,5%),celiac disease(n=5,3%),neuroendocrine tumor(n=3,2%),Crohn’s disease(n=2,<2%),Peutz-Jeghers syndrome(n=2,<2%),other polyposes(n=2,<2%),and diarrhea(n=2,<2%).The capsule reached the colon in 115(76.6%)examinations.In 150 investigations,CE identified 15SB tumors(10%),14 of which were operated on or treated endoscopically.Malignancies included metastatic melanoma(n=1),adenocarcinoma(n=2),and GIST(n=3).Benign neoplasms included dysplastic Peutz-Jeghers polyps(n=4).Non-neoplastic masses included venous malformation(n=1),inflammatory tumors(n=2),and a mass of unknown histology(n=1).During the follow-up period,three additional SB tumors were found(2 GISTs and one mesenteric tumor of undefined nature).The National Cancer Registry and Polish Clinical GIST Registry revealed no additional SB neoplasms in the post-examination period(follow-up:range 4.2-102.5 mo,median 39 mo).The sensitivity of CE for tumor detection was 83.3%,and the negative predictive value was 97.6%.The specificity and positive predictive value were both 100%.CONCLUSION:Neoplasms may be missed by CE,especially in the proximal SB.In overt obscure gastrointestinal bleeding,complementary endoscopic and/or radiologic diagnostic tests are indicated. | Edyta S Zagorowicz Anna M Pietrzak Ewa Wronska Jacek Pachlewski Piotr Rutkowski Ewa Kraszewska Jaroslaw Regula | 2013 | World Journal of Gastroenterology2013,19,47: | 10 |
| 10 | 先进航空材料焊接过程热裂纹研究进展显示文摘高焊接热裂纹敏感性是制约新一代合金材料在航空航天领域推广应用的技术瓶颈。本文分别从焊接热裂纹的产生机理和各类合金裂纹敏感性实验的角度梳理该方向的研究进展。焊接热裂纹主要包括凝固裂纹(在焊缝内部产生)和液化裂纹(在焊缝与部分熔化区交界处产生)。影响焊接热裂纹产生的因素包括材料成分、焊接热循环以及接头热应力。在梳理焊接热裂纹机理研究的基础上,分别总结了铝合金、镁合金、先进高强钢以及镍基合金焊接热裂纹的实验研究进展。建立考虑复杂多组元以及结晶形态对裂纹敏感性影响的量化判据,是该领域未来的重要发展方向。针对母材和焊材进行成分优化、添加形核剂或实施辅助工艺措施,是工程应用领域抑制热裂纹缺陷的有效方法。开展焊接热裂纹产生机理及其抑制方法研究,有助于突破新一代合金材料加工技术瓶颈,推进其在航空航天领域的应用。 | 李红 闫维嘉 张禹 杜文博 栗卓新 MARIUSZ Bober SENKARA Jacek | 2022 | 材料工程2022,50,2: | 9 |
| 11 | Neutrophil engagement and septic challenge in acute experimental pancreatitis in rats显示文摘AIM: To investigate the influence of neutrophil adhesion molecule blockade with monoclonal antibody (MoAb CD11b) and E. coli lipopolysaccharide (LPS)administration on experimental acute pancreatitis (AP).METHODS: AP was induced by four ip injections of cerulein (Cn) at 1-h intervals. MoAb CD 11b and LPS were administered at the beginning of the experiment.RESULTS: The neutrophil count and chemiluminescence were diminished at the beginning of AP. The oxidative stress parameters were found within the pancreatic gland. MoAb CD 11b used for AP resulted in a significant reduction of pancreatic infiltration and pancreatitis oxidative stress parameters. Serum interleukin-6 (IL-6)was not detected in AP animals, whereas high serum IL-6 concentration was noted only in animals receiving LPS.CONCLUSION: Neutrophils are involved in pancreatic damage in the early stage of AP. Neutrophil infiltration reduction protects the pancreatic gland from destruction during AP. LPS does not change the early course of Cn pancreatitis in rats. | Stanisiaw Ha Marek Dobosz Jan J Kaczor Robert Rzepko Ewa Aleksandrowicz-Wrona Zdzislaw Wajda Zbigniew ledzi■ski Jacek Krajewski | 2005 | World Journal of Gastroenterology2005,11,41: | 7 |
| 12 | Immunological Aspects of the Statins' Function in Patients with Heart Failure:A Report from the Annual Conference of ESC-Heart Failure 2005显示文摘The annual meeting of the Heart Failure Association of ESC in Lisbon, in June 2005, was exceptionally successful.There were many very interesting presentations and workshops with the unique title: Statins in heart failureCholesterol-lowering is not the only goal Heart failure (HF) is a progressive disease with coronary artery disease (CAD) as the most often underlying etiology. Treatment to prevent progression of heart failure has been targeted to reverse the consequences of HF and to a less extent the cause - the atherosclerotic plaque itself. On the average 50% of patients with heart failure are treated with lipid intervention. Lipid-lowering treatment with statins clearly reduces morbidity and mortality of patients with documented CAD. Since the prevalent etiology of heart failure is CAD, its prevention may reduce heart failure progression. However, recent studies suggest that pleiotropic effects of statins are more important than the influence related to their cholesterol lowering mechanism. Furthermore it is suggested that low levels of circulating lipoproteins and cholesterol may be independent predictors of impaired outcome in patients with heart failure. There are some possible explanations for this finding. High levels of cholesterol can be beneficial to heart failure patients; cholesterol-rich serum lipoproteins are able to modulate inflammatory immune function because they bind and detoxify bacterial lipopolysaccharide, a very strong stimulator of the release of proinflammatory cytokines that promote heart failure progression and death. So current recommendations strongly emphasize that the aim of treatment of HF is not to lower cholesterol. | Maciej Banach Jarostaw Drozdz Piotr Okonski Jacek Rysz | 2005 | Cellular & Molecular Immunology2005,2,6: | 7 |
| 13 | 高熵合金在钎焊和表面工程领域的应用研究进展显示文摘随着合金制造水平的提高及性能要求的复杂化,高熵合金逐渐引起极大的关注。目前在材料加工领域内的研究主要集中于钎焊和表面工程两大方向。在钎焊领域,高熵合金可以作为钎焊填充材料应用于高温和低温钎焊,本文归纳了合金高熵化的相关经验参数,阐述了第一性原理计算和相图计算等模拟计算手段在高熵合金填充材料设计领域内的应用;详细介绍了高熵合金钎料在镍基高温合金、陶瓷-金属异种材料、低温封装等连接领域的最新研究进展。同时,分析了工艺参数对高熵合金钎料钎焊接头组织与性能的影响。在表面工程领域,论述了高熵合金薄膜/涂层的应用方向与制备手段,总结了在高温防护涂层、硬质保护层以及其他应用领域的研究进展。同时归纳了高熵合金在钎焊和表面工程领域研究和应用中存在的问题,而未来将在降低钎料熔点、提高焊缝高温力学性能以及发展共晶高熵合金钎料/涂层等领域进一步提高研究水平。 | 李红 韩祎 曹健 MARIUSZ Bober JACEK Senkara | 2021 | 材料工程2021,49,8: | 7 |
| 14 | Generalized Predictive Control for Superheated Steam Temperature Regulation in a Supercritical Coal-fired Power Plant显示文摘The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive MovingAverage(CARMA)model of the plant is derived from using the experimental data to approximately predict the plant’s future behavior.This model is required by the GPC algorithm to calculate the future control inputs.A new GPC controller is designed and its performance is tested through extensive simulation studies.Compared with the performance of the plant using a conventional PID controller,the steam temperature controlled by the GPC controller is found to be more stable.The stable steam temperature leads to more efficient plant operation and energy saving,as demonstrated by the simulation results.Plant performance improvement is also tested while the plant experiences the load demand changes and disturbances resulting from the malfunctioning of coal mills. | Mihai Draganescu Shen Guo Jacek Wojcik Jihong Wang Xiangjie Liu Guolian Hou Yali Xue Qirui Gao | 2015 | CSEE Journal of Power and Energy Systems2015,1,1: | 7 |
| 15 | Modeling of Thermal Properties of Thermal Insulation Layered with Transparent,Opaque and Reflective Film显示文摘The popular and effective food preservation technology based on refrigeration is not sufficient for high-quality products while undergoing logistic operations(transport and retail). One of the basic factors that affects the quality of chilled and frozen food products during storage and transport is packaging. A protective function of packaging strongly depends on the material used and its composition. There are different kinds of thermal insulation used for food packaging. One of them, proposed by the authors is a multilayer structure of insulation made of rectangular air cells. The insulation can be prepared by means of plastic film featuring various properties. The paper presents how to improve an effective material designed for food freezing and transport aiming to enhance its thermal resistance through the application of different transparency, reflectivity and emissivity of the film. Mathematical model based on heat exchange equations, including conduction, convection and radiation throughout a number of parallel internal sheets of film of multilayer structures was proposed. Thermal properties depending on different transparency, reflectivity and emissivity of the film were analyzed. The model was verified experimentally showing its compatibility and obtaining a significant influence of thermal resistance according to the type of film used to make air structures, the number and thickness of its layers as well as the gaps between internal folds. For multi-layer insulation designed for the insulation of packed frozen food in the shape of a rectangle, it was recommended to apply film transmittance as small as possible for the internal parts of the structure. | GRABOWSKA Beata KASPERSKI Jacek | 2018 | Journal of Thermal Science2018,27,5: | 4 |
| 16 | 不同外加碳源和电子受体对生物营养盐去除工艺中反硝化和除磷过程的影响(英文)显示文摘目的:考察两种不同性质的外加碳源(乙酸钠和乙醇)在三种不同的电子受体(溶解氧、硝酸盐和亚硝酸盐)条件下对聚磷菌和异养菌的影响机制。创新点:系统研究了乙酸钠和乙醇这两种外加碳源在溶解氧、硝酸盐和亚硝酸盐三种不同电子受体条件下的释磷、吸磷及反硝化过程。方法:利用具有脱氮除磷功能的活性污泥,开展了一系列一阶段批次试验和两阶段批次试验。一阶段批次试验包括厌氧释磷试验、好氧吸磷试验、硝酸盐及亚硝酸盐利用速率(NUR)试验。两阶段批次试验包括厌氧/好氧试验、厌氧/缺氧试验。通过改变外加碳源的投加条件,如投加类型(乙酸钠和乙醇)、投加环境(厌氧、好氧和缺氧)、缺氧区电子受体(硝酸盐及亚硝酸盐),考察两种不同类型的外加碳源在不同电子受体条件下对除磷和脱氮过程的影响。结论:(1)当乙酸钠作为外加碳源时,在溶解氧、硝酸盐和亚硝酸盐三种不同电子受体条件下均发生了释磷,释磷速率分别为1.70、7.80和3.50 mg P/(g MLVSS·h)。当乙醇作为外加碳源时,三种电子受体条件下均未发现有释磷。(2)无论乙酸钠还是乙醇作为外加碳源,未经驯化的活性污泥聚磷菌均不能利用亚硝酸盐作为电子受体,25 mg NO2-N/L的亚硝酸盐完全抑制了吸磷过程的进行。(3)以硝酸盐作为电子受体时,乙酸钠和乙醇的NUR值分别为2.3和1.5 mg N/(g MLVSS·h),比亚硝酸盐作电子受体的NUR值(分别为1.2和1.0 mg N/(g MLVSS·h))分别高出92%和50%。乙酸钠作为碳源的NUR值总是比相同条件下以乙醇作为碳源的NUR值高。 | Xiang HU Dominika SOBOTKA Krzysztof CZERWIONKA Qi ZHOU Li XIE Jacek MAKINIA | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018,19,4: | 3 |
| 17 | Weiwoboidae fam.nov.of 'Higher' Fulgoroidea (Hemiptera:Fulgoromorpha) from the Eocene Deposits of Yunnan,China显示文摘所谓的更高的 planthoppers 的一个新家庭, Weiwoboidae fam。nov,从更低云南始新世被描述。一个新 monotypic 类, Weiwoboa 情报。nov,与 Weiwoboa meridiana sp。nov。也被描述并且说明。新家庭,它的进化,和建议关系的复翅脉络的人物简短被讨论。 | LIN Qibin Jacek SZWEDO HUANG Diying Adam STROINSKI | 2010 | Acta Geologica Sinica(English Edition)2010,84,4: | 3 |
| 18 | Uremic Pruritus: A Clinical Study of Maintenance Hemodialysis Patients显示文摘 | Jacek C. Szepietowski Magdalena Sikora Mariusz Kusztal Joanna Salomon Maria Magott Tomasz Szepietowski | 2002 | The Journal of Dermatology2002,,10: | 3 |
| 19 | Barriers to axonal regeneration after spinal cord injury:a current perspective显示文摘Regeneration of long axons after the spinal cord injury(SCI)will benefit patients with extensive traumatic damage to the white matter pathways who experience intolerable,permanent,neurologic deficits even after neuroprotective treatment with anti-inflammatory agents(Kwiecien,2021a).This short paper attempts to synthetize pathologic mechanisms or barriers involved in inhibition of axonal regeneration in the SCI and provides suggestions of therapeutic interventions enabling this regeneration in animal models. | Jacek M.Kwiecien | 2022 | Neural Regeneration Research2022,17,1: | 3 |
| 20 | 严重肢体缺血患者血浆中促血管生成潜力与血浆MMP-9、TIMP-1和TIMP-2水平升高的相关性研究(英文)显示文摘本研究通过比较间歇性跛行(IC)和严重肢体缺血(CLI)患者的血液参数,选择合适的临床和生化特指标,以评估促血管生成的潜力和抑制血管生成的作用.结果表明,通过刺激下肢动脉疾病(LEAD)病人血浆中的血管生成,内皮生长因子A(VEGF-A)浓度会显著增加,同时依赖于循环受体sVEGFR-1和sVEGFR-2的抑制也会显著减少.与IC病人相比,CLI病人具有较高的VEGF-A、金属蛋白酶9(MMP-9)、金属蛋白酶组织抑制因子1(TIMP-1)和TIMP-2浓度. | Radoslaw Wieczór Anna Maria Wieczór Arleta Kulwas Grzegorz Pulkowski Jacek Budzyński Danuta Rosc | 2019 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2019,20,8: | 3 |