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| 1 | Highly efficient Cu/anatase TiO2 {001}-nanosheets catalysts for methanol synthesis from CO2显示文摘Anatase TiO_2 nanosheets(-ns-) with dominant exposed {001} facets were used as support to load copper,and the synthesized Cu/TiO_2-ns catalysts were evaluated for CO_2 hydrogenation to methanol. Under the reaction conditions, P = 3.0 MPa, T = 260 ℃, V(N_2):V(H_2):V(CO_2) = 8:69:23 and gas hourly space velocity(GHSV) = 3600 mL g^(-1)h^(-1), the methanol yield reached an appealing high value, 5.6%. Copper-loading amount, calcination temperature and reduction atmosphere have been investigated in this work, which significantly influence the particle sizes of copper and/or the defect concentration in TiO_2, then leading to different catalytic performance. Characterizations of XRD, EPR, CO_2-TPD and FTIR demonstrate that higher specific surface area of Cu is good for the hydrogenation of CO_2 and adequate amount of Ti^(3+) plays important roles in CO_2 activation. Both of them facilitate high turnover frequency(TOF) of methanol formation. | Yunfeng Bao Chunlei Huang Limin Chen Yu dong Zhang Long Liang Jinjun Wen Mingli Fu Junliang Wu Daiqi Ye | 2018 | Journal of Energy Chemistry2018，27，2： | 7 |
| 2 | Rett syndrome-causing mutations compromise MeCP2- mediated liquid—liquid phase separation of chromatin显示文摘Rett syndrome(RTT),a severe postnatal neurodevelopmental disorder,is caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2(MeCP2).MeCP2 is a chromatin organizer regulating gene expression.RTT-causing mutations have been shown to affect this function.However,the mechanism by which MeCP2 organizes chromatin is unclear.In this study,we found that MeCP2 can induce compaction and liquid-liquid phase separation of nudeosomal arrays in vitro,and DNA methylation further enhances formation of chromatin condensates by MeCP2.Interestingly,RTT-causing mutations compromise MeCP2-mediated chromatin phase separation,while benign variants have little effect on this process.Moreover,MeCP2 competes with linker histone H1 to form mutually exclusive chromatin condensates in vitro and distinct heterochromatin foci in vivo.RTT-causing mutations reduce or even abolish the ability of MeCP2 to compete with histone H1 and to form chromatin condensates.Together,our results identify a novel mechanism by which phase separation underlies MeCP2-mediated heterochromatin formation and reveal the potential link between this process and the pathology of RTT. | Liang Wang Mingli Hu Mei-Qing Zuo Jicheng Zhao Di Wu Li Huang Yongxin Wen Yunfan Li Ping Chen Xinhua Bao Meng-Qiu Dong Guohong Li Pilong Li | 2020 | Cell Research2020，30，5： | 3 |
| 3 | Structural Deformation Monitoring of Flight Vehicles Based on Optical Fiber Sensing Technology:A Review and Future Perspectives显示文摘Structural deformation monitoring of flight vehicles based on optical fiber sensing(OFS)technology has been a focus of research in the field of aerospace.After nearly 30 years of research and development,Chinese and international researchers have made significant advances in the areas of theory and methods,technology and systems,and ground experiments and flight tests.These advances have led to the development of OFS technology from the laboratory research stage to the engineering application stage.However,a few problems encountered in practical applications limit the wider application and further development of this technology,and thus urgently require solutions.This paper reviews the history of research on the deformation monitoring of flight vehicles.It examines various aspects of OFS-based deformation monitoring including the main varieties of OFS technology,technical advantages and disadvantages,suitability in aerospace applications,deformation reconstruction algorithms,and typical applications.This paper points out the key unresolved problems and the main evolution paradigms of engineering applications.It further discusses future development directions from the perspectives of an evolution paradigm,standardization,new materials,intelligentization,and collaboration. | Lianqing Zhu Guangkai Sun Weimin Bao Zheng You Fanyong Meng Mingli Dong | 2022 | Engineering2022，，9： | 1 |
| 4 | Flash pyrolysis of agricultural residues using a plasma heated laminar entrained flow reactor显示文摘 | Xiu Shuangning Yi Weiming Bao mingLi | 2005 | Biomass and Bioenergy2005，，29： | 1 |
| 5 | Log odds of positive lymph nodes显示文摘 | ZheSun YanXu De MingLi Zhen NingWang Guo LianZhu Bao JunHuang KaiLi Hui MianXu | 2010 | Cancer2010，，11： | 1 |
| 6 | Flash pyrolysis of agricultural residues using a plasma heated laminar entrained flow reactor显示文摘 | Xiu Shuangning Yi Weiming Bao mingLi | 2005 | Biomass and Bioenergy2005，29，： | 1 |
| 7 | A gap-free reference genome reveals structural variations associated with flowering time in rapeseed(Brassica napus)显示文摘Allopolyploid oilseed rape(Brassica napus)is an important oil crop and vegetable.However,the latest version of its reference genome,with collapsed duplications,gaps,and other issues,prevents comprehensive genomic analysis.Herein,we report a gap-free assembly of the rapeseed cv.Xiang5A genome using a combination of ONT(Oxford Nanopore Technologies)ultra-long reads,PacBio high-fidelity reads,and Hi-C datasets.It includes gap-free assemblies of all 19 chromosomes and telomere-to-telomere assemblies of eight chromosomes.Compared with previously published genomes of B.napus,our gap-free genome,with a contig N50 length of 50.70 Mb,has complete assemblies of 9 of 19 chromosomes without manual intervention,and greatly improves contiguity and completeness,thereby representing the highest quality genome assembly to date.Our results revealed that B.napus Xiang5A underwent nearly complete triplication and allotetraploidy relative to Arabidopsis thaliana.Using the gap-free assembly,we found that 917 flowering-related genes were affected by structural variation,including BnaA03.VERNALIZATION INSENSITIVE 3 and BnaC04.HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1.These genes may play crucial roles in regulating flowering time and facilitating the adaptation of Xiang5A in the Yangtze River Basin of China.This reference genome provides a valuable genetic resource for rapeseed functional genomic studies and breeding. | Bao Li Qian Yang Lulu Yang Xing Zhou Lichao Deng Liang Qu Dengli Guo Rongkui Hui Yiming Guo Xinhong Liu Tonghua Wang Lianyi Fan Mei Li Mingli Yan | 2023 | Horticulture Research2023，10，10： | 0 |
| 8 | Targeted mutations of BnPAP2 lead to a yellow seed coat in Brassica napus L.显示文摘The yellow seed trait is preferred by breeders for its potential to improve the seed quality and commercial value of Brassica napus.In the present study,we produced yellow seed mutants using a CRISPR/Cas9 system when the two BnPAP2 homologs were knocked out.Histochemical staining of the seed coat demonstrated that proanthocyanidin accumulation was significantly reduced in the pap2 double mutants and decreased specifically in the endothelial and palisade layer cells of the seed coat.Transcriptomic and metabolite profiling analysis suggested that disruption of the BnPAP2 genes could reduce the expression of structural and regulated genes in the phenylpropanoid and flavonoid biosynthetic pathways.The broad suppression of these genes might hinder proanthocyanidin accumulation during seed development,and thereby causing the yellow seed trait in B.napus.These results indicate that BnPAP2 might play a vital role in the regulatory network controlling proanthocyanidin accumulation. | Wei Huang Ruyu Jiao Hongtao Cheng Shengli Cai Jia Liu Qiong Hu Lili Liu Bao Li Tonghua Wang Mei Li Dawei Zhang Mingli Yan | 2024 | Journal of Integrative Agriculture2024，23，2： | 0 |
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