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| 1 | Hybrid graphene metasurfaces for highspeed mid-infrared light modulation and single-pixel imaging显示文摘During the past decades,major advances have been made in both the generation and detection of infrared light;however,its efficient wavefront manipulation and information processing still encounter great challenges.Efficient and fast optoelectronic modulators and spatial light modulators are required for mid-infrared imaging,sensing,security screening,communication and navigation,to name a few.However,their development remains elusive,and prevailing methods reported so far have suffered from drawbacks that significantly limit their practical applications.In this study,by leveraging graphene and metasurfaces,we demonstrate a high-performance free-space mid-infrared modulator operating at gigahertz speeds,low gate voltage and room temperature.We further pixelate the hybrid graphene metasurface to form a prototype spatial light modulator for high frame rate single-pixel imaging,suggesting orders of magnitude improvement over conventional liquid crystal or micromirror-based spatial light modulators.This work opens up the possibility of exploring wavefront engineering for infrared technologies for which fast temporal and spatial modulations are indispensable. | Beibei Zeng Zhiqin Huang Akhilesh Singh Yu Yao Abul K.Azad Aditya D.Mohite Antoinette J.Taylor David R.Smith Hou-Tong Chen | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | 小鼠骨骼肌挫伤后基因表达的时间进程(英文)显示文摘Background:Though the mechanisms of skeletal muscle regeneration are deeply understood,those involved in muscle contusion,one of the most common muscle injuries in sports medicine clinics,are not.The objective of this study is to explore the mechanisms involved in muscle regeneration after contusion injury.Methods:In this study,a total of 72 mice were used.Eight of them were randomly chosen for the control group,while the rest were subjected to muscle contusion.Subsequently,their gastrocnemius muscles were harvested at different time points.The changes in muscle morphology were assessed by hematoxylin and eosin(HE) stain.In addition,the gene expression was analyzed by real-time polymerase chain reaction.Results:The data showed that the expression of many genes,i.e.,specific markers of immune cells and satellite cells,regulatory factors for muscle regeneration,cytokines,and chemokines,increased in the early stages of recovery,especially in the first 3 days.Furthermore,there were strict rules in the expression of these genes.However,almost all the genes returned to normal at 14 days post-injury.Conclusion:The sequence of immune cells invaded after muscle contusion was neutrophils,M1 macrophages and M2 macrophages.Some CC(CCL2,CCL3,and CCL4) and CXC(CXCL10) chemokines may be involved in the chemotaxis of these immune cells.HGF may be the primary factor to activate the satellite cells after muscle contusion.Moreover,2 weeks are needed to recover when acute contusion happens as used in this study. | Weihua Xiao Yu Liu Beibei Luo Linlin Zhao Xiaoguang Liu Zhigang Zeng Peijie Chen | 2016 | Journal of Sport and Health Science2016，5，1： | 8 |
| 3 | Different meridian tropism in three Chinese medicines: Tinglizi(Semen Lepidii Apetali), Yiyiren(Semen Coicis), Cheqianzi(Semen Plantaginis)显示文摘OBJECTIVE: To study the meridian tropism(MT) for three Chinese medicines: Tinglizi(Semen Lepidii Apetali, TLZ), Yiyiren(Semen Coicis, YYR), Cheqianzi(Semen Plantaginis, CQZ) in vivo experiments.METHODS: The extracts of TLZ,YYR, CQZ were orally administered to rats at a dose 234, 700 and 350 mg/kg, respectively. The urinary excretion rate, loss in weight of rats and the electrolyte levels in the plasma were measured, in order to assess the mechanisms of the three traditional Chinese diuretic medicines.RESULTS: TLZ, YYR and CQZ exhibited obvious diuretic effect and reduced the weight of saline-loaded animals. All the three diuretic medicines differentially reduced various serum, urinary, lung, stomach, kidney and hormonal markers, thus indicating the different mechanisms of action and a close resemblance with their different meridian as per the MT theory.CONCLUSION: Our findings suggest that the three Traditional Chinese Medicine(TCM) medicines-TLZ,YYR and CQZ-possess different Shamisen meridian.This can support the regimen of treating the same disease with different therapies in TCM theory. | Zeng Mengnan Li Miao Zhang Li Zhang Beibei Wu Guangcao Feng Weisheng Zheng Xiaoke | 2019 | Journal of Traditional Chinese Medicine2019，39，2： | 4 |
| 4 | Magnetic properties and magnetocaloric effects in amorphous and crystalline Gd_(55)Co_(35)Ni_(10) ribbons显示文摘The magnetic properties and magnetocaloric effects of amorphous and crystalline Gd55Co35Ni10 ribbons are investigated.A main phase with a Ho 12 Co 7-type monoclinic structure(space group P21/c) and a minor phase with a Ho4Co3-type hexagonal structure(space group P63/m) are obtained for crystalline ribbon after annealing.The amorphous ribbons order ferromagnetically and undergo a second-order transition at 192 K.For crystalline Gd55Co35Ni10 ribbons,two magnetic phase transitions occur at 158 and 214 K,respectively.The peak value of-△SM under a field change of 0-5 T is 6.5 J/kg K at 192 K for amorphous Gd55Co35Ni10 ribbons.A relatively large magnetic entropy change(~5.0 J/kg K) under a field change of 0-5 T for the crystalline Gd55Co35Ni10 ribbons is obtained in the temperature interval range of 154-214 K.The large platform of magnetic entropy change and the negligible thermal/magnetic hysteresis loss mean the crystalline Gd55Co35Ni10 compound can satisfy the requirement of the Ericsson-type refrigerator working in the temperature range from 154K to 214K. | ZHONG XiChun TANG PengFei GAO BeiBei MIN JiXiong LIU ZhongWu ZHENG ZhiGang ZENG DeChang YU HongYa QIU WanQi | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，6： | 3 |
| 5 | Simultaneous Cr(VI) reduction and phenol degradation in pure cultures of Pseudomonas aeruginosa CCTCC AB91095显示文摘 | Huaxiao Song Yunguo Liu Weihua Xu Guangming Zeng Nuzaaiti Aibibu Li Xu Beibei Chen | 2009 | Bioresource Technology2009，，21： | 1 |
| 6 | Rift Valley Fever Virus and Yellow Fever Virus in Urine: A Potential Source of Infection显示文摘Dear Editor,In recent years,the incidence of human infections caused by emerging or re-emerging pathogens has rapidly increased.Diseases that were once regional now have the ability to spread globally in a short amount of time and pose a wider threat to public health(Weaver et al.2018).Yellow fever virus(YFV,family Flaviviridae,genus Flavivirus)is a mosquito-borne flavivirus that causes yellow fever in humans and has been endemic in Africa and Latin America for many years(Domingo et al.2018). | Meng Li Beibei Wang Liqiang Li Gary Wong Yingxia Liu Jinmin Ma Jiandong Li Hongzhou Lu Mifang Liang Ang Li Xiuqing Zhang Yuhai Bi Hui Zeng | 2019 | Virologica Sinica2019，34，3： | 1 |
| 7 | Enhanced sodium storage performance in flexible free- standing multichannel carbon nanofibers with enlarged interlayer spacing显示文摘一个灵活、自立的多信道的碳 nanofiber (MCNF ) 电影电极通过 electrospinning 和碳化被制作。在在真空的 MCNF 的高温度的处理以后,获得的纤维(MCNFs-V ) 有 graphene 表(0.398 nm ) 和一个极端低的特定的表面区域的扩大夹层间距(15.3 m 2/g) 。当为钠离子电池用作阳极时, MCNFs-V 证明在 0.1 V 下面的一个分泌物高原,和钠在 sodiation 过程期间被设置进叠的 graphene 表层。MCNFs-V 在 100 个周期和优秀长期的骑车稳定性以后在 0.1 A/g 的当前的密度展出了 222 mAh/g 的一个可逆、高的特定的能力,它比 MCNF 的优异。改进的钠存储表演为钠置闰与 graphene 表的扩大夹层间距被归因于 MCNFs-V 的唯一的微观结构。MCNFs-V 电极为商业钠离子电池作为阳极材料保持大诺言。 | Beibei Yuan Linchao Zeng Xizhen Sun Yan Yu Qingsong Wang | 2018 | Nano Research2018，11，4： | 1 |
| 8 | Cadmium accumulation in vetiveria zizanioides and its effects on growth, physiological and biochemical characters显示文摘 | Nuza’aiti Aibibu Yunguo Liu Guangming Zeng Xin Wang Beibei Chen Huaxiao Song Li Xu | 2010 | Bioresource Technology2010，，16： | 1 |
| 9 | Synthesis and Characterization of Novel Hydrolytically Degradable Polyesters显示文摘Six novel hydrolytically degradable polyesters were synthesized from thiodipropionic acid(TDPA)and five diols by melt polycondensation,and characterized by FT-IR,1H NMR,gel permeation chromatography,differential scanning calorimetry and thermogravimetry analysis.The polystyrene-equivalent number-average(Mn)and weight-average molecular weight(Mw)of these polyesters ranged from 4900-11100 Da and 7900-20879 Da,respectively,with PDI values of 1.48-1.98.The melting point varied from 62.3-127.9℃,and the 50%mass-loss temperature ranged between 387-417℃.The degradation of these polyesters was studied in terms of relative weight loss in distilled water at different pH.Weight losses of 14%-26%were obtained at pH 7.0,26%-38%at pH 6.0,and 32%-43%at pH 8.3 over a 20-week period.The ecotoxicity study suggested that safety of the synthesized polyesters for the eisenia foetida.These results indicate that these polyesters have a combination of good thermal and degradability behaviors,which can be tailored through selection of the diol monomers used in the synthesis. | SUN Xin CHENG Zhengzai DJOUONKEP Lesly Dasilva Wandji LAN Chupeng JIA Ruyan ZENG Sheng CHENG Junpeng TANG Ran LI Yi YUAN Beibei GAUTHLLER Mario | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，2： | 0 |
| 10 | Physicochemical properties and antibacterial application of silver nanoparticles stabilized by whey protein isolate显示文摘Nano metal materials have been widely explored to be applied in medical,environmental,and material science.Among these nanoparticles,especially silver nanoparticles(AgNPs),have drawn increasing attention for antimicrobial applications.Most researchers are keen on the development of the biologically friendly capping reagents for the synthesis of AgNPs,instead of unfriendly organic polymers.In this study,the liquid chemical reduction method was used to synthesize AgNPs with edible whey protein isolate(WPI)as a capping reagent.These WPI-AgNPs had a broad size distribution(average diameter of 138.6 nm),and their dimensions could be readily controlled in the range of 22.5-149.6 nm by introducing different concentrations of chloride.Subsequently,it was confirmed that WPI-AgNPs were formed through two mechanisms,which were respectively reduced in situ(without the addition of NaCl)and ex situ(in presence of NaCl)to yield silver nanoparticles.The WPI-AgNPs synthesized in presence of 10 mM of NaCl as mediation reagent were stable at room temperature or 4℃ up to 3 months.Furthermore,the synthesized WPI-AgNPs had a good antibacterial activity toward pathogens including Gram-negative E.coli and Gram-positive S.aureus.The results shed light on method and capping reagent to stabilize silver nanoparticles,which highlighted the potential of WPI and chloride in metal nanoparticle synthesis. | Aoqiong Zeng Beibei Wang Cheng Zhang Ruijin Yang Shuhuai Yu Wei Zhao | 2022 | Food Bioscience2022，46，2： | 0 |
| 11 | High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast显示文摘The characteristic genetic abnormality of neuroendocrine neoplasms(NENs),a heterogeneous group of tumors found in various organs,remains to be identified.Here,based on the analysis of the splicing variants of an oncogene Focal Adhesion Kinase(FAK)in The Cancer Genome Atlas datasets that contain 9193 patients of 33 cancer subtypes,we found that Box 6/Box 7-containing FAK variants(FAK^(6/7))were observed in 7(87.5%)of 8 pancreatic neuroendocrine carcinomas and 20(11.76%)of 170 pancreatic ductal adenocarcinomas(PDACs).We tested FAK variants in 157 tumor samples collected from Chinese patients with pancreatic tumors,and found that FAK^(6/7)was positive in 34(75.6%)of 45 pancreatic NENs,19(47.5%)of 40 pancreatic solid pseudopapillary neoplasms,and 2(2.9%)of 69 PDACs.We further tested FAK splicing variants in breast neuroendocrine carcinoma(BrNECs),and found that FAK^(6/7)was positive in 14(93.3%)of 15 BrNECs but 0 in 23 non-NEC breast cancers.We explored the underlying mechanisms and found that a splicing factor serine/arginine repetitive matrix protein 4(SRRM4)was overexpressed in FAK^(6/7)-positive pancreatic tumors and breast tumors,which promoted the formation of FAK^(6/7)in cells.These results suggested that FAK^(6/7)could be a biomarker of NENs and represent a potential therapeutic target for these orphan diseases. | Dawei Xie Zheng Wang Beibei Sun Liwei Qu Musheng Zeng Lin Feng Mingzhou Guo Guizhen Wang Jihui Hao Guangbiao Zhou | 2023 | Frontiers of Medicine2023，17，5： | 0 |
| 12 | Tunable plasmofluidic lens for subwavelength imaging显示文摘A tunable plasmofluidic lens consisting of nanoslit arrays on a metal film is proposed for subwavelength imaging in far field at different wavelengths.The nanoslit arrays with constant depths but varying widths could generate desired optical phase retardations based on the propagation property of the surface plasmon polaritons(SPPs)through the metal-dielectric-metal(MDM)nanoslit waveguide.We demonstrate the tunability of the plasmofluidic lens for subwavelength imaging by changing the surrounding dielectric fluid.This work provides a novel approach for developing integrative tunable plasmofluidic lens for a variety of lab-on-chip applications. | Beibei Zeng | 2017 | 光电工程2017，44，3： | 0 |
| 13 | Ephedra Herb extract ameliorates adriamycin-induced nephrotic syndrome in rats via the CAMKK2/AMPK/mTOR signaling pathway显示文摘This study aimed to investigate the effect and mechanisms of Ephedra Herb(EH)extract on adriamycin-induced nephrotic syndrome(NS),providing an experimental basis for the clinical treatment of NS.Hematoxylin and eosin staining,creatinine,urea nitrogen,and kidn injury molecule-1 were used to evaluate the activities of EH extract on renal function.The levels of inflammatory factors and oxidative stress were detected by kits.The levels of reactive oxygen species,immune cells,and apoptosis were measured by flow cytometry.A network pharmacological approach was used to predict the potential targets and mechanisms of EH extract in the treatment of NS.The protein levels of apoptosis-related proteins and CAMKK2,p-CAMKK2,AMPK,p-AMPK,mTOR and p-mTOR in the kidneys were detected by Western blot.The effective material basis of EH extract was screened by MTT assay.The AMPK pathway inhibitor(compound C,CC)was added to investigate the effect of the potent material basis on adriamycin-induced cell injury.EH extract significantly improved renal injury and relieve inflammation,oxidative stress,and apoptosis in rats.Network pharmacology and Western blot results showed that the effect of EH extract on NS may be associated with the CAMKK2/AMPK/mTOR signaling pathway.Moreover,methylephedrine significantly ameliorated adriamycin-induced NRK-52e cell injury.Methylephedrine also significantly improved the phosphorylation of AMPK and mTOR,which were blocked by CC.In sum,EH extract may ameliorate renal injury via the CAMKK2/AMPK/mTOR signaling pathway.Moreover,methylephedrine may be one of the material bases of EH extract. | ZHANG Yuhan ZENG Mengnan LI Benke ZHANG Beibei CAO Bing WU Yuanyuan YE Shan XU Ruiqi ZHENG Xiaoke FENG Weisheng | 2023 | Chinese Journal of Natural Medicines2023，21，5： | 0 |
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