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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Polyamines reduces lipid peroxidation induced by different pro-oxidant agents显示文摘 | Nádia Aléssio Velloso Bellé Gerusa Duarte Dalmolin Graciela Fonini Maribel Antonello Rubin Jo?o Batista Teixeira Rocha | 2004 | Brain Research2004，，2： | 3 |
| 3 | Monitoring dioxins and PCBs in eggs as sensitive indicators for environmental pollution and global contaminated sites and recommendations for reducing and controlling releases and exposure显示文摘This review compiles information on PCDD/F-and PCB-contaminated eggs from 20 years of global egg monitoring around emission sources in four continents conducted by the International Pollutants Elimination Network(IPEN)and Arnika as well as a compilation of data from scientific literature.IPEN monitored 127 pooled egg samples including samples from 113 chicken flocks at potential PCDD/F-and PCB-contaminated sites around priority sources listed in the Stockholm Convention(e.g.waste incinerators,metal industries,cement plants,and open burning).99(88%)of pooled egg samples were above the EU maximum limits for PCDD/Fs(2.5 pg PCDD/F-TEQ/g fat)or the sum of PCDD/Fs and dioxinlike PCBs(5 pg PCDD/F-PCB-TEQ/g fat).Children consuming such eggs exceed the tolerable weekly intake(TWI).This demonstrates that close to 90%of these areas were not safe for the production of free-range eggs.Sixteen out of the 113 egg samples(14%)were contaminated above 50 pg TEQ/g fat and exceeded the EU maximum limit more than 10 times.From the 26 pooled egg samples around incinerators 24(92%)exceeded the limit with a mean of 43.1 pg TEQ/g fat(2.6e234 pg TEQ/g).All 21 egg samples around metal industries(4.4e112.6 pg TEQ/g fat)were above limits with mean concentration of 26.0 pg TEQ/g fat.Also all 7 egg samples measured at e-waste recycling sites were above limits(mean 308 pg TEQ/g fat).In 58(51%)pooled egg samples the PCB-TEQ was above 5 pg TEQ/g fat exceeding the EU maximum limit with dioxin-like PCBs alone.This highlights the role of commercial PCBs for global contamination with dioxin-like compounds.It was discovered that around metal industries,shredder plants,open burning sites of e-waste and dump sites,a high share of contamination was caused by dl-PCBs.This clearly shows severe PCB release from the end-of-life management of PCB-containing equipment in developing countries.Also highly contaminated eggs were found at many sites where plastic was incinerated.The highest contaminated egg sample ever measured came from an e-waste site in Ghana and had 856 pg TEQ/g fat plus 300 pg TEQ from brominated dioxins(PBDD/Fs).Other extreme PCDD/F contaminations of eggs were found at a chlor-alkali site(514 pg TEQ/g fat),Agent Orange contaminated areas in Vietnam(490,249 and 246 pg TEQ/g fat)and e-waste sites(568 and 520 pg TEQ/g fat).Where DR CALUX®bioassay revealed higher TEQ compared to measured PCDD/F-PCB-TEQ in IPEN studies,polybrominated PBDD/F were also measured and detected up to 300 pg TEQ/g fat at e-waste sites.One positive outcome from the IPEN studies is that all 10 pooled supermarket eggs in developing countries were below regulatory limit.Policy recommendations are made including:a systematic assessment of areas around PCDD/Fs and PCBs sources;measures for reduction of exposures of populations;urgent control of emission sources including PCB equipment,the open burning of plastic,and the use of plastic as fuel in boilers/incinerators in developing countries without air pollution control.Furthermore,soil limits need to be re-assessed and lowered for free-range poultry. | Jindrich Petrlik Lee Bell Joe DiGangi Serge Molly Allo'o Allo'o Gilbert Kuepouo Griffins Ochieng Ochola Valeriya Grechko Nikola Jelinek Jitka Strakova Martin Skalsky Yuyun Ismawati Drwiega Jonathan N.Hogarh Eric Akortia Sam Adu-Kumi Akarapon Teebthaisong Maria Carcamo Bjorn Beeler Peter Behnisch Claudia Baitinger Christine Herold Roland Weber | 2022 | Emerging Contaminants2022，8，1： | 2 |
| 4 | Abundance and partitioning of OH in a hlgh-pressure magmatic system: Megacrysts from the Monastery kimberlite, South Africa显示文摘 | Bell D B Rossman G R Moore R O | 2004 | J Petrol2004，45，： | 1 |
| 5 | Visual Interactive Simulation-Histroy,Recent Developments and Major Issues显示文摘 | Robert M O'Keefe | 1987 | Simulation1987，49，3： | 1 |
| 6 | A annotated checklist of the mosses of Europe and Macaronesia 显示文摘 | Hill M O Bell N Bruggeman-Nannenga M A | 2006 | Journal of Bryology2006，28，： | 1 |
| 7 | Differential induction of 3-hydroxy-3-methylglutaryl CoA reductase in two cotton species following inoculation with Verticillium 显示文摘 | JOOST O Bianchini G Bell A A | 1995 | Molecular Plant-Microbe Interactions1995，8，6： | 1 |
| 8 | Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis显示文摘 | Van Belle V Van Calster B Brouckaert O | 2010 | J Clin Oncol2010，28，27： | 1 |
| 9 | BirA En- zyme: Production and Application in the Study of Mem- brane Receptor - Ligand Interactions by Site-Specific Biotinylation Original Research 显示文摘 | O'Callaghan C A Byford M F Wyer J R Willcox BE Jakobsen B K McMichael A J Bell J 1 | 1999 | Anal Biochem1999，266，1： | 1 |
| 10 | Epidemiology and outcomes of acute renal failure in hospitalized patients : a national survey 显示文摘 | Liangos O Wald R O'Bell JW | 2006 | Clin J Am Soc Nephrol2006，1，1： | 1 |
| 11 | Cooperative Catalyst Effects in Palladium-Mediated Cyanation Reactions of Aryl Halides and Triflates 显示文摘 | Anderson B A Bell E C Ginah F O | 1998 | J Org Chem1998，63，23： | 1 |
| 12 | Fatigue crack growth of semi-elliptical surface Cracks显示文摘 | McFadyen N B Bell R Vosikovsky O | 1990 | International Journal of Fatigue1990，12，1： | 1 |
| 13 | Growth of silicon sheets for photovoltaic applications 显示文摘 | R O Bell J P Kaleis | 1998 | J Mater Res1998，13，： | 1 |
| 14 | Defect passivation in multicrystalline-Si materials by plasma-enhanced chemical vapor deposition of SiO2/SiN coatings显示文摘 | Chen Z Rohatgi A Bell R O | 1994 | Applied Physics Letters1994，65，16： | 1 |
| 15 | Epidemiology and outcomes of acute renal failure in hospitalized patients:a national survey显示文摘 | Liangos O Wald R O' Bell JW | 2006 | Clin J Am Soc Nephrol2006，，1： | 1 |
| 16 | Performance of Finishing Pigs Fed Canola Meal in Growing and Finishing Diets显示文摘 | Bell J M Keith M O | 1988 | Nutr Rep Int1988，38，： | 1 |
| 17 | Vitamin D deficiency: animportant, common, and easily treatable cardiovascular riskfactor显示文摘 | Lee JH O'Keefe JH Bell D | 2008 | J Am Coll Cardiol2008，52，24： | 1 |
| 18 | Report of large motor reliability survey of industrial and commercial installations (II) 显示文摘 | Bell R N Heising C R O'Donnell P | 1985 | IEEE Transactions on Industry Applications1985，21，4： | 1 |
| 19 | Epidemiology and outcomes of acute renal failure in hospitalized patients:a national survey显示文摘 | Liangos O Wald R O' Bell JW | | 0，，01： | 1 |
| 20 | Posterolateral rotatory instability of the elbow显示文摘 | O' Driscoll SW Bell DF Morrey BF | | 0，，： | 1 |
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