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| 1 | Peripheral nerve regeneration and intraneural revascularization显示文摘Peripheral nerves are particularly vulnerable to injuries and are involved in numerous pathologies for which specific treatments are lacking. This review summarizes the pathophysiological features of the most common traumatic nerve injury in humans and the different animal models used in nerve regeneration studies. The current knowledge concerning Wallerian degeneration and nerve regrowth is then described. Finally, the involvement of intraneural vascularization in these processes is addressed. As intraneural vascularization has been poorly studied, histological experiments were carried out from rat sciatic nerves damaged by a glycerol injection. The results, taken together with the data from literature, suggest that revascularization plays an important role in peripheral nerve regeneration and must therefore be studied more carefully. | Martial Caillaud Laurence Richard Jean-Michel Vallat Alexis Desmoulière Fabrice Billet | 2019 | Neural Regeneration Research2019，14，1： | 20 |
| 2 | Characterisation and seasonal variations of particles in the atmosphere of rural, urban and industrial areas:Organic compounds显示文摘Atmospheric aerosol samples(PM_(2.5–0.3), i.e., atmospheric particles ranging from 0.3 to2.5 μm) were collected during two periods: spring–summer 2008 and autumn–winter 2008–2009, using high volume samplers equipped with cascade impactors. Two sites located in the Northern France were compared in this study: a highly industrialised city(Dunkirk) and a rural site(Rubrouck). Physicochemical analysis of particulate matter(PM) was undertaken to propose parameters that could be used to distinguish the various sources and to exhibit seasonal variations but also to provide knowledge of chemical element composition for the interpretation of future toxicological studies. The study showed that PM2.5–0.3concentration in the atmosphere of the rural area remains stable along the year and was significantly lower than in the urban or industrial ones, for which concentrations increase during winter.High concentrations of polycyclic aromatic hydrocarbons(PAHs), dioxins, furans and dioxin like polychlorinated biphenyls(DL-PCBs), generated by industrial activities, traffic and municipal wastes incineration were detected in the samples. Specific criteria like Carbon Preference Index(CPI) and Combustion PAHs/Total PAHs ratio(CPAHs/TPAHs) were used to identify the possible sources of atmospheric pollution. They revealed that paraffins are mainly emitted by biogenic sources in spring–summer whereas as in the case of PAHs, they have numerous anthropogenic emission sources in autumn-winter(mainly from traffic and domestic heating). | Fabrice Cazier Paul Genevray Dorothée Dewaele Habiba Nouali Anthony Verdin Frédéric Ledoux Adam Hachimi Lucie Courcot Sylvain Billet Saad Bouhsina Pirouz Shirali Guillaume Garcon Dominique Courcot | 2016 | Journal of Environmental Sciences2016，28，6： | 4 |
| 3 | Local effects of mifepristone on the nonhuman primate endometrium显示文摘 | Victoria Jimenez-Moreno Michelle Billeter Cheng quan Liu Keith Gordon Mary Mahony | 2000 | Fertility and Sterility2000，，1： | 2 |
| 4 | Smoothelin,a new marker to determine the origin of liver fibrogenic cells显示文摘AIM:To explore this hypothesis that smooth muscle cells may be capable of acquiring a myofibroblastic phenotype,we have studied the expression of smoothelin in fibrotic conditions.METHODS:Normal liver tissue(n=3)was obtained from macroscopically normal parts of hepatectomy,taken at a distance from hemangiomas.Pathological specimens included post-burn cutaneous hypertrophic scars(n=3),fibrotic liver tissue(n=5),cirrhotic tissue(viral and alcoholic hepatitis)(n=5),and hepatocellular carcinomas(n=5).Tissue samples were fixed in 10%formalin and embedded in paraffin for immunohistochemistry or were immediately frozen in liquid nitrogen-cooled isopentane for confocal microscopy analysis.Sections were stained with antibodies against smoothelin,which is expressed exclusively by smooth muscle cells,andα-smooth muscle actin,which is expressed by both smooth muscle cells and myofibroblasts.RESULTS:In hypertrophic scars,α-smooth muscle actin was detected in vascular smooth muscle cells and in numerous myofibroblasts present in and around nodules,whereas smoothelin was exclusively expressed in vascular smooth muscle cells.In the normal liver,vascular smooth muscle cells were the only cells that expressα-smooth muscle actin and smoothelin.In fibrotic areas of the liver,myofibroblasts expressingα-smooth muscle actin were detected.Myofibroblasts co-expressingα-smooth muscle actin and smoothelin were observed,and their number was slightly increased in parallel with the degree of fibrosis(absent in liver with mild or moderate fibrosis;5%to 10%positive in liver showing severe fibrosis).In cirrhotic septa,numerous myofibroblasts co-expressedα-smooth muscle actin and smoothelin(more than 50%).In hepatocellular carcinomas,the same pattern of expression forα-smooth muscle actin and smoothelin was observed in the stroma reaction surrounding the tumor and around tumoral cell plates.In all pathological liver samples,α-smooth muscle actin and smoothelin were co-expressed in vascular smooth muscle cells.CONCLUSION:During development of advanced liver fibrosis,a subpopulation of myofibroblasts expressing smoothelin may be derived from vascular smooth muscle cells,illustrating the different cellular origins of myofibroblasts. | Sébastien Lepreux Christelle Guyot Fabrice Billet Chantal Combe Charles Balabaud Paulette Bioulac-Sage Alexis Desmoulière | 2013 | World Journal of Gastroenterology2013，19，48： | 2 |
| 5 | Unintentional perioperative hypothermia is associated with severe complications and high mortality in elective operations显示文摘 | Adrian T. Billeter Samuel F. Hohmann Devin Druen Robert Cannon Hiram C. Polk | 2014 | Surgery2014，，： | 2 |
| 6 | Early Serum Procalcitonin, Interleukin-6, and 24-Hour Lactate Clearance: Useful Indicators of Septic Infections in Severely Traumatized Patients显示文摘 | Adrian Billeter Matthias Turina Burkhardt Seifert Ladislav Mica Reto Stocker Marius Keel | 2009 | World Journal of Surgery2009，，3： | 2 |
| 7 | Adapative control of flexural waves propagating in a beam 显示文摘 | Elliott S J Billet L | 1993 | Journal of Sound and Vibration:1993，163，2： | 1 |
| 8 | In vivo activity of the hepatitis B virus core promoter:Tissue specificity and temporal regulation 显示文摘 | Billet O Grimber G Levrero M | 1995 | J Virol1995，69，： | 1 |
| 9 | Reverse genetics meets the non segmented negate vestr and RNA viruses 显示文摘 | RADECKE F BILLETER M A | 1997 | Med Virol1997，，7： | 1 |
| 10 | Real-time multiple scattering using light propagation volumes 显示文摘 | Billeter Markus Erik Sintom Ulf Assarsson | 2012 | I3D 12 (S 1017-4656) 2012: 119-1262012，312，10174656： | 1 |
| 11 | Homeodomain-DNA recognition显示文摘 | Gehring WJ Qian YQ Billeter M | 1994 | Cell1994，78，： | 1 |
| 12 | Tetrachlorodibenzodioxin isomer differentiation by micro diffuse reflectance fourier transform infrared spectrometry at the low nanogram level显示文摘 | Gurka D F Billets S Brasch J W | 1985 | Anal Chem1985，57，9： | 1 |
| 13 | Effect of hypoxia on muscular performance eapaeity: Living Low-Training High显示文摘 | VOGT M BILLETER R HOPPELER H | 2003 | Ther Umseh2003，60，7： | 1 |
| 14 | Reverse genetics meets the non seg- mented negattive-strand vestr and RNA viruses 显示文摘 | Radecke F Billeter M A | 1997 | Med Virol1997，7，： | 1 |
| 15 | Hepatitis B virus X gene product acts as a transactivator in vivo显示文摘 | Balsano C Billet O Bennoun M | 1994 | J Hepatol1994，21，1： | 1 |
| 16 | The call of duty:Self-organized task allocation in a population of up twelve mobile robots显示文摘 | Keriger M J B Billeter J -B | 2000 | Robot and Autonomous Systems2000，30，： | 1 |
| 17 | The theologies of transparency in Europe: The limits and possibilities of 'fusion' in the EU transparency regime 显示文摘 | Billet S | 2007 | Public Affairs2007，7，4： | 1 |
| 18 | P-4-73 A randomized double-bind trial of risperidone versus clozapine for treatment-resistant chronic schizophrenia显示文摘 | G. Bondolfi P. Baumann M. Patris J.P. May U. Billeter H. Dufour | 1995 | European Neuropsychopharmacology1995，，： | 1 |
| 19 | Reverse genetics of measles virus and resulting muhivalent recombinant vaccines: applications of recombinant measles viruses 显示文摘 | Billeter MA Naim HY Udem SA | 2009 | Curr Top Microbiol Immunol2009，329，1： | 1 |
| 20 | Modeling of Pressure Drop in Packed Column显示文摘 | Billet R Schultes M | 1991 | Chem Eng Technol1991，14，2： | 1 |
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