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| 1 | A Review on Cable-driven Parallel Robots显示文摘Cable-driven parallel robots(CDPRs) are categorized as a type of parallel manipulators. In CDPRs, flexible cables are used to take the place of rigid links. The particular property of cables provides CDPRs several advantages, including larger workspaces, higher payload-to-weight ratio and lower manufacturing costs rather than rigid-link robots. In this paper, the history of the development of CDPRs is introduced and several successful latest application cases of CDPRs are presented. The theory development of CDPRs is introduced focusing on design, performance analysis and control theory. Research on CDPRs gains wide attention and is highly motivated by the modern engineering demand for large load capacity and workspace. A number of exciting advances in CDPRs are summarized in this paper since it is proposed in the 1980 s, which points to a fruitful future both in theory and application. In order to meet the increasing requirements of robot in different areas, future steps foresee more in-depth research and extension applications of CDPRs including intelligent control, composite materials, integrated and reconfigurable design. | Sen Qian Bin Zi Wei-Wei Shang Qing-Song Xu | 2018 | Chinese Journal of Mechanical Engineering2018，31，4： | 19 |
| 2 | Molecular Epidemiological Characteristics of Streptococcus pyogenes Strains Involved in an Outbreak of Scarlet Fever in China,2011显示文摘Objective To investigate molecular characterization of streptococcus pyogenes isolates involved in an outbreak of scarlet fever in China in 2011.Methods Seventy-four Streptococcal pyogenes involved in an outbreak of scarlet fever were isolated from pediatric patients in the areas with high incidence in China from May to August of 2011.Emm genotyping,pulsed-field gel electrophoresis (PFGE),superantigen (SAg) genes and antimicrobial susceptibility profiling were analyzed for these isolates.Results A total of 4 different emm types were identified.Emm12 was the most prevalent type which contained four predominating PFGE patterns corresponding to four different virulence and superantigen profiles.Emm12 (79.7%) and emml (14.9%) accounted for approximately 94%of all the isolates.The speA gene was all negative in emm12 isolates and positive in emml isolates.All strains were resistant to erythromycin,and 89.4%of them were resistant to erythromycin,tracycline,and clindamycin simultaneously.Conclusion Several highly diversified clones with a high macrolide resistance rate comprise a predominant proportion of circulating strains,though no new emm type was found in this outbreak.The data provide a baseline for further surveillance of scarlet fever,which may contribute to the explanation of the outbreak and development of a GAS vaccine in China. | YOU Yuan Hai SONG Yan Yan YAN Xiao Mei WANG Hai Bin ZHANG Meng Han TAO Xiao Xia Li Lei Lei ZHANG Yu Xin JIANG Xi Hong ZHANG Bing Hua ZHOU Hao XIAO Di JIN Lian Mei FENG Zi Jian LUO Feng Ji ZHANG Jian Zhong | 2013 | Biomedical and Environmental Sciences2013，26，11： | 15 |
| 3 | Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma显示文摘With the understanding of the complex interaction between the tumour microenvironment and immunotherapy,there is increasing interest in the role of immune regulators in the treatment of head and neck squamous cell carcinoma(HNSCC).Activation of T cells and immune checkpoint molecules is important for the immune response to cancers.Immune checkpoint molecules include cytotoxic T lymphocyte antigen 4(CTLA-4),programmed death 1(PD-1),T-cell immunoglobulin mucin protein 3(TIM-3),lymphocyte activation gene 3(LAG-3),T cell immunoglobin and immunoreceptor tyrosine-based inhibitory motif(TIGIT),glucocorticoid-induced tumour necrosis factor receptor(GITR)and V-domain Ig suppressor of T cell activation(VISTA).Many clinical trials using checkpoint inhibitors,as both monotherapies and combination therapies,have been initiated targeting these immune checkpoint molecules.This review summarizes the functional mechanism and use of various immune checkpoint molecules in HNSCC,including monotherapies and combination therapies,and provides better treatment options for patients with HNSCC. | Zi Mei Junwen Huang Bin Qiao Alfred King-yin Lam | 2020 | International Journal of Oral Science2020，12，2： | 14 |
| 4 | Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography显示文摘Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography(OCTA) based on optical microangiography(OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA(Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density(VAD), vessel skeleton density(VSD), vessel diameter index(VDI), vessel perimeter index(VPI), vessel complexity index(VCI), flux, and foveal avascular zone(FAZ). Coefficient of variation(CV) and intraclass correlation coefficient(ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility. Results The measurements showed high repeatability [CVs ≤ 4.2%(intravisit) and ≤ 4.6%(intervisit)] and interobserver reproducibility(ICCs ≥ 0.923) for all parameters. Conclusion This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes. | ZHAO Qi YANG Wen Li WANG Xiao Na Ruikang K Wang YOU Qi Sheng CHU Zhong Di XIN Chen ZHANG Meng Yu LI Dong Jun WANG Zi Yang CHEN Wei LI Yi Feng CUI Rui SHEN Lin WEI Wen Bin | 2018 | Biomedical and Environmental Sciences2018，31，6： | 8 |
| 5 | Algebraic Method‑Based Point‑to‑Point Trajectory Planning of an Under‑Constrained Cable‑Suspended Parallel Robot with Variable Angle and Height Cable Mast显示文摘To avoid impacts and vibrations during the processes of acceleration and deceleration while possessing flexible working ways for cable-suspended parallel robots(CSPRs),point-to-point trajectory planning demands an under-constrained cable-suspended parallel robot(UCPR)with variable angle and height cable mast as described in this paper.The end-effector of the UCPR with three cables can achieve three translational degrees of freedom(DOFs).The inverse kinematic and dynamic modeling of the UCPR considering the angle and height of cable mast are completed.The motion trajectory of the end-effector comprising six segments is given.The connection points of the trajectory segments(except for point P3 in the X direction)are devised to have zero instantaneous velocities,which ensure that the acceleration has continuity and the planned acceleration curve achieves smooth transition.The trajectory is respectively planned using three algebraic methods,including fifth degree polynomial,cycloid trajectory,and double-S velocity curve.The results indicate that the trajectory planned by fifth degree polynomial method is much closer to the given trajectory of the end-effector.Numerical simulation and experiments are accomplished for the given trajectory based on fifth degree polynomial planning.At the points where the velocity suddenly changes,the length and tension variation curves of the planned and unplanned three cables are compared and analyzed.The OptiTrack motion capture system is adopted to track the end-effector of the UCPR during the experiment.The effectiveness and feasibility of fifth degree polynomial planning are validated. | Tao Zhao Bin Zi Sen Qian Jiahao Zhao | 2020 | Chinese Journal of Mechanical Engineering2020，33，4： | 7 |
| 6 | miR-145 improves metabolic inflammatory disease through multiple pathways显示文摘Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagnosed diabetic patients than in normal control.miR-145 level in peripheral blood mononuclear cells decreased in type 2 diabetics.LPS repressed the transcription of miR-143/145 cluster and decreased miR-145 levels.Attenuation of miR-145 activity by anti-miR-145 triggered liver inflammation and increased serum chemokines in C57BL/6 J mice.Conversely,lentivirus-mediated miR-145 overexpression inhibited macrophage infiltration,reduced body weight,and improved glucose metabolism in db/db mice.And miR-145 overexpression markedly reduced plaque size in the aorta in ApoE−/−mice.Both OPG and KLF5 were targets of miR-145.miR-145 repressed cell proliferation and induced apoptosis partially by targeting OPG and KLF5.miR-145 also suppressed NF-κB activation by targeting OPG and KLF5.Our findings provide an association of the environment with the progress of metabolic disorders.Increasing miR-145 may be a new potential therapeutic strategy in preventing and treating metabolic diseases such as type 2 diabetes and atherosclerosis. | Min He Nan Wu Man Cheong Leong Weiwei Zhang Zi Ye Rumei Li Jinyang Huang Zhaoyun Zhang Lianxi Li Xiao Yao Wenbai Zhou Naijia Liu Zhihong Yang Xuehong Dong Yintao Li Lili Chen Qin Li Xuanchun Wang Jie Wen Xiaolong Zhao Bin Lu Yehong Yang Qinghua Wang Renming Hu | 2020 | Journal of Molecular Cell Biology2020，12，2： | 7 |
| 7 | Exposure Effects of Terahertz Waves on Primary Neurons and Neuron-like Cells Under Nonthermal Conditions显示文摘Objective This study aimed to explore the potential effects of terahertz(THz) waves on primary cultured neurons from 4 rat brain regions(hippocampus, cerebral cortex, cerebellum, and brainstem)and 3 kinds of neuron-like cells(MN9 D, PC12, and HT22 cells) under nonthermal conditions.Methods THz waves with an output power of 50(0.16 THz) and 10(0.17 THz) m W with exposure times of 6 and 60 min were used in this study. Analysis of temperature change, neurite growth, cell membrane roughness, micromorphology, neurotransmitters and synaptic-related proteins(SYN and PSD95) was used to evaluate the potential effects.Results Temperature increase caused by the THz wave was negligible. THz waves induced significant neurotransmitter changes in primary hippocampal, cerebellar, and brainstem neurons and in MN9 D and PC12 cells. THz wave downregulated SYN expression in primary hippocampal neurons and downregulated PSD95 expression in primary cortical neurons.Conclusion Different types of cells responded differently after THz wave exposure, and primary hippocampal and cortical neurons and MN9 D cells were relatively sensitive to the THz waves. The biological effects were positively correlated with the exposure time of the THz waves. | TAN Sheng Zhi TAN Peng Cheng LUO Lan Qing CHI Yun Liang YANG Zi Long ZHAO Xue Long ZHAO Li DONG Ji ZHANG Jing YAO Bin Wei XU Xin Ping TIAN Guang CHEN Jian Kui WANG Hui PENG Rui Yun | 2019 | Biomedical and Environmental Sciences2019，32，10： | 5 |
| 8 | Synthesis and Luminescent Properties of Eu^(3+)-Doped Na_(24)P_2W_(22)O_(83)显示文摘The Eu3+-doped Na24P2W22O83 has been prepared by solid state reaction, and characterized by element analysis, infrared spectroscopy, powder X-ray diffractometry. The emission and excitation spectra were measured. The luminescence properties of Eu3+-doped Na24P2W22O83 and the energy transfer mechanism were discussed. | Shui Jin YANG Ju Tang SUN and Zi Bin QIN(Depaltment of Chemistry, Hubei Normal University, Huangshi, 435002 Department of Chemistry, Wuhan University, Wuhan 430072) | 1998 | Chinese Chemical Letters1998，9，10： | 5 |
| 9 | Insulating materials for realising carbon neutrality:Opportunities,remaining issues and challenges显示文摘The 2050 carbon-neutral vision spawns a novel energy structure revolution,and the construction of the future energy structure is based on equipment innovation.Insulating material,as the core of electrical power equipment and electrified transportation asset,faces unprecedented challenges and opportunities.The goal of carbon neutral and the urgent need for innovation in electric power equipment and electrification assets are first discussed.The engineering challenges constrained by the insulation system in future electric power equipment/devices and electrified transportation assets are investigated.Insulating materials,including intelligent insulating material,high thermal conductivity insulating material,high energy storage density insulating material,extreme environment resistant insulating material,and environmental-friendly insulating material,are cat-egorised with their scientific issues,opportunities and challenges under the goal of carbon neutrality being discussed.In the context of carbon neutrality,not only improves the understanding of the insulation problems from a macro level,that is,electrical power equipment and electrified transportation asset,but also offers opportunities,remaining issues and challenges from the insulating material level.It is hoped that this paper en-visions the challenges regarding design and reliability of insulations in electrical equipment and electric vehicles in the context of policies towards carbon neutrality rules.The authors also hope that this paper can be helpful in future development and research of novel insulating materials,which promote the realisation of the carbon-neutral vision. | Chuanyang Li Yang Yang Guoqiang Xu Yao Zhou Mengshuo Jia Shaolong Zhong Yu Gao Chanyeop Park Qiang Liu Yalin Wang Shakeel Akram Xiaoliang Zeng Yi Li Fangwei Liang Bin Cui Junpeng Fang Lingling Tang Yulin Zeng Xingtao Hu Jiachen Gao Giovanni Mazzanti Jinliang He Jianxiao Wang Davide Fabiani Gilbert Teyssedre Yang Cao Feipeng Wang Yunlong Zi | 2022 | High Voltage2022，7，4： | 4 |
| 10 | Conclusions in Theory and Practice for Advancing the Applications of Cable-Driven Mechanisms显示文摘The theoretical research of cable-driven mechanisms is developed with its broad applications.The first prototype of cable-driven mechanisms is Robo Crane,which was developed by the National Institute of Standards and Technology(NIST).Then many excellent properties were developed and they have a variety of applications such | Bin Zi Yuan Li | 2017 | Chinese Journal of Mechanical Engineering2017，30，4： | 3 |
| 11 | Effects of Blast Wave-induced Biomechanical Changes on Lung Injury in Rats显示文摘Objective To observe the dynamic impacts of shock waves on the severity of lung injury in rats with different injury distances.Methods Simulate open-field shock waves;detect the biomechanical effects of explosion sources at distances of 40,44,and 48 cm from rats;and examine the changes in the gross anatomy of the lungs,lung wet/dry weight ratio,hemoglobin concentration,blood gas analysis,and pathology.Results Biomechanical parameters such as the overpressure peak and impulse were gradually attenuated with an increase in the injury distance.The lung tissue hemorrhage,edema,oxygenation index,and pathology changed more significantly for the 40 cm group than for the 44 and 48 cm groups.The overpressure peak and impulse were significantly higher for the 40 cm group than for the 44 and 48 cm groups(P<0.05 or P<0.01).The animal mortality was significantly higher for the 40 cm group than for the other two groups(41.2%vs.17.8%and 10.0%,P<0.05).The healing time of injured lung tissues for the 40 cm group was longer than those for the 44 and 48 cm groups.Conclusions The effects of simulated open-field shock waves on the severity of lung injuries in rats were correlated with the injury distances,the peak overpressure,and the overpressure impulse. | LIU Wei CHAI Jia Ke QIN Bin HAN Shao Fang WANG Xiao Teng JIANG Shuai BAI Hai Liang LIU Ling Ying CHANG Yang YUE Xiao Tong WU Yu Shou ZHANG Zi Hao TANG Lang | 2020 | Biomedical and Environmental Sciences2020，33，5： | 2 |
| 12 | The Influence of Diabetes, Hypertension, and Hyperlipidemia on the Onset of Age-Related Macular Degeneration in North China: The Kailuan Eye Study显示文摘Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cross-sectional epidemiologic study was conducted involving 14,440 individuals.We assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for AMD.Results The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,respectively.The prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2%,and 0.7%,respectively.The prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2%,15.2%,and 17.2%,respectively.Age,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of AMD.Diabetes,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were analyzed.None of the factors analyzed in the current study increased the risk for the onset of AMD.Conclusion There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic subjects.Similarly,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and hyperlipidemia.Diabetes co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD. | ZHANG Yong Peng WANG Ya Xing ZHOU Jin Qiong WANG Qian YAN Yan Ni YANG Xuan YANG Jing Yan ZHOU Wen Jia WANG Ping SHEN Chang YANG Ming LUAN Ya Nan WANG Jin Yuan WU Shou Ling CHEN Shuo Hua WANG Hai Wei FANG Li Jian WAN Qian Qian ZHU Jing Yuan NIE Zi Han CHEN Yu Ning XIE Ying JONAS JB WEI Wen Bin | 2022 | Biomedical and Environmental Sciences2022，35，7： | 2 |
| 13 | Aurora kinase small molecule inhibitor destructs mitotic spindle, suppresses cell growth, and induces apoptosis in oral squamous cancer cells显示文摘 | Chao Bin Pan Hong Zhang Huang Min Yan Jine Yao Jie Xu Zi Jie Long | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 2 |
| 14 | Amination of electron deficient aryl chlorides promoted by nano sized Mg(OH)_2 under transition metals free condition显示文摘这份报纸论述缺乏的芳基氯化物由 Mg 支持了的电子的胺化作用反应(哦) 2 没有转变金属。仅仅用 stoichiometric, nano 的数量缩放 Mg (哦) 2,对中等孤立的收益好能在 150 在 24 h 以后在 N-methylpyrrolidone (NMP ) | Zhi Hao Cui Zi Hui Meng Yan Qing Mi Peng Wang Qi Wang Lin Man Zhao Ke Jian Cui Fang Yu Zhi Bin Xu | 2012 | Chinese Chemical Letters2012，23，2： | 2 |
| 15 | An Inves- tigation of Thermal Characteristics of a Liquid-cooled Mag- netorheological Fluid-based Clutch 显示文摘 | WANG Daoming ZI Bin ZENG Yishan | 2015 | Smart Materials and Structures2015，24，05： | 1 |
| 16 | Tab engineering-mediated resistance of flexible lithium-ion batteries for high output current显示文摘Flexible lithium-ion batteries(LIBs) have received tremendous interest because they can provide essential flexible power for the emerging wearable electronics.However,the realization of the flexibility of LIBs is often related to flexible substrates with high electrical resistance,which results in voltage loss of the battery and is unfavorable for their practical applications.In this work,we demonstrated the use of tab engineering to mediate the resistance of flexible batteries for high current output.The resistance of the obtained pouch cell can be decreased sharply and the output current can be significantly increased by a continuous tab with desirable power and energy density.The surprising performance of the flexible LIBs allows the tab on the current collector providing enough channels for electron transfer,thus enabling electrons to be transferred quickly and enhancing the electrochemical reaction kinetics.Such a flexible battery with sufficient output current could possibly solve some of the most critical problems for their practical applications in wearable electronics. | Shi Kui Jia Bin Ze Yang Chao Feng Zhao Zhi Yong Zhang Yan Hong Yin Xian Bin Liu Ying Yan Hu Zi Ping Wu | 2021 | Journal of Energy Chemistry2021，30，7： | 1 |
| 17 | Dynamic analysis and active control of a cable-suspended parallel robot显示文摘 | ZI Bin DUAN Baoyan DU Jingli | 2008 | Mechatronics2008，18，1： | 1 |
| 18 | Localization,obstacle avoidance planning and control of a cooperative cable parallel robots for multiple mobile cranes显示文摘 | ZI Bin LIN Jun QIAN Sen | 2015 | Robotics and Computer-Integrated Manufacturing2015，34，： | 1 |
| 19 | Design and analysis of a pneumatic muscle driven parallel mechanism for imitating human pelvis显示文摘 | ZHAO Xinwei ZI Bin | 2014 | Proceedings of the Institution of Mechanical Engineers Part C:Journal of Mechanical Engineering Science2014，228，4： | 1 |
| 20 | Analysis and control of the cable-supporting system including actuator dynamics显示文摘 | Zi Bin Zhu Zhencai Du Jingli | 2011 | Control Engineering Practice2011，19，5： | 1 |
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