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您的检索式：作者名="Boris Y.Rubinstein"
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| 1 | Gas-assisted microfluidic step-emulsification forgenerating micron- and submicron-sized droplets显示文摘Micron- and submicron-sized droplets have extensive applications in biomedical diagnosis and drug delivery.Moreover, accurate high-throughput analysis requires a uniform droplet size distribution and high production rates.Although the previously reported microfluidic coflow step-emulsification method can be used to generate highlymonodispersed droplets, the droplet diameter (d) is constrained by the microchannel height (b), d\3b, while theproduction rate is limited by the maximum capillary number of the step-emulsification regime, impedingemulsification of highly viscous liquids. In this paper, we report a novel, gas-assisted coflow step-emulsificationmethod, where air serves as the innermost phase of a precursor hollow-core air/oil/water emulsion. Air graduallydiffuses out, producing oil droplets. The size of the hollow-core droplets and the ultrathin oil layer thickness bothfollow the scaling laws of triphasic step-emulsification. The minimal droplet size attains d 1:7b, inaccessible instandard all-liquid biphasic step-emulsification. The production rate per single channel is an order-of-magnitudehigher than that in the standard all-liquid biphasic step-emulsification and is also superior to alternative emulsificationmethods. Due to low gas viscosity, the method can also be used to generate micron- and submicron-sized droplets ofhigh-viscosity fluids, while the inert nature of the auxiliary gas offers high versatility. | Biao Huang Xinjin Ge Boris Y.Rubinstein Xianchun Chen Lu Wang Huiying Xie Alexander M.Leshansky Zhenzhen Li | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
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