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| 1 | Acrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injury显示文摘In the hours to weeks following traumatic spinal cord injuries(SCI), biochemical processes are initiated that further damage the tissue within and surrounding the initial injury site: a process termed secondary injury. Acrolein, a highly reactive unsaturated aldehyde, has been shown to play a major role in the secondary injury by contributing significantly to both motor and sensory deficits. In particular, efforts have been made to elucidate the mechanisms of acrolein-mediated damage at the cellular level and the resulting paralysis and neuropathic pain. In this review, we will highlight the recent developments in the understanding of the mechanisms of acrolein in motor and sensory dysfunction in animal models of SCI. We will also discuss the therapeutic benefits of using acrolein scavengers to attenuate acrolein-mediated neuronal damage following SCI. | Jonghyuck Park Breanne Muratori Riyi Shi | 2014 | Neural Regeneration Research2014，9，7： | 6 |
| 2 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 3 | Satellite to demonstrate mar- itime surveillance for coast guard显示文摘 | Stew M Breanne W | 2005 | National Defense2005，92，650： | 1 |
| 4 | Emotional Experience and Interaction Design显示文摘 | Youn-kyung Lim Justin Donaldson Heekyoung Jung Breanne Kunz David Royer Shruti Ramalingam Sindhia Thirumaran and Erik Stolterman | | 0，，： | 1 |
| 5 | Active Fe-Containing Superoxide Dismutase and Abundant sodF mRNA in Nostoc commune (Cyanobacteria) after Years of Desiccation显示文摘 | Breanne Shirkey Don Paul Kovarcik Malcolm Potts | 2000 | J Bacteriol2000，182，1： | 1 |
| 6 | Chronic Interferon-Alpha Administration Disrupts Sleep Continuity and Depth in Patients with Hepatitis C: Association with Fatigue, Motor Slowing, and Increased Evening Cortisol显示文摘 | Charles L. Raison David B. Rye Bobbi J. Woolwine Gerald J. Vogt Breanne M. Bautista James R. Spivey Andrew H. Miller | 2010 | Biological Psychiatry2010，，10： | 1 |
| 7 | The Choice to limit Choice;Using Psychiatruc Advance Directives to Manage the Effects of Mental Illness and Support Self-responsibility显示文摘 | Breanne M S | 2007 | University of Michigan Journal of Law Reform2007，401，： | 1 |
| 8 | The relationship among internal resilience, smoking, alcohol use, and depression symptoms in emerging adults transitioning out of child welfare 显示文摘 | Abby L Goldstein M Breanne F | 2013 | Child Abuse Negl2013，37，1： | 1 |
| 9 | Enhancement of intestinal permeability utilizing solid lipid nanoparticles in- creases c-tocotrienol oral bioavailability 显示文摘 | BILAL S A COURTNEY L BREANNE P | 2012 | Lipid2012，47，1： | 1 |
| 10 | 蜂蜜与蜜蜂显示文摘不要提醒我
有时候我是挡风玻璃
其他时候我是幸运的虫子
这些冰冷的铁轨
留下布满青苔的古老痕迹 | Owl City feat Breanne Dren 小狐 | 2011 | 疯狂英语(初中天地)2011，，10： | 0 |
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