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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Hope or No-HOPE-- Merit-Based College Scholarship Status and Financial Behaviors Among College Students 显示文摘 | JOSEPH W D BRENDA J C | 2008 | Financial Counseling and Planning2008，，1： | 1 |
| 3 | Myeoplasmas and Ureaplasmas as Neonatal Pathogens 显示文摘 | Ken B W Brenda K Robert L S | 2005 | Clin Micro Rev2005，18，4： | 1 |
| 4 | Evidence for enzyme complexes in the phenylpropanoid and flavonoid pathways显示文摘 | Brenda W S | 1999 | Physiologia Plantarum1999，107，1： | 1 |
| 5 | Molecular sensing of 3-chloro-1,2-propanediol by molecular imprinting显示文摘 | Leung Mitch K P Chiu Brenda K W Lam Michael H W | 2003 | Analytica Chimica Acta2003，491，： | 1 |
| 6 | Usability testing of an aca- demic library Web site: a case study显示文摘 | Brenda B Austin B Jane W | 2001 | The Journal of Aca- demic Librarianship2001，27，3： | 1 |
| 7 | Biosynthesis of flavonoids and effects of stress显示文摘 | Brenda W S | 2002 | Current opinion Plant 13iology2002，5，3： | 1 |
| 8 | Attitudes about a Resort Area: A Comparison of Tourists and Local Retailers显示文摘 | Brenda S W | 1985 | Journal of Travel Research1985，4，1： | 1 |
| 9 | Attitudes about a Resort Area:A Comparison of Tourists and Local Retailers显示文摘 | Brenda S W | 1985 | Journal of Travel Research1985，4，1： | 1 |
| 10 | Flavonoid biosynthesis: A colorful model for genetics, biochemistry ,cell biology and biotechnology 显示文摘 | | 2001 | Plant Physiol2001，126，： | 1 |
| 11 | 25 years of the WHO essential medicines lists: progress and challenges 显示文摘 | Richard L Brenda W Andy G | 2003 | Lancet2003，361，10： | 1 |
| 12 | Frequency dependence of antidepressant response to left prefrontal repetitive transcranial magnetic stimulation (rTMS) as a function of baseline cerebral glucose metabolism显示文摘 | Timothy A Kimbrell John T Little Robert T Dunn Mark A Frye Benjamin D Greenberg Eric M Wassermann Jennifer D Repella Aimee L Danielson Mark W Willis Brenda E Benson Andrew M Speer Elizabeth Osuch Mark S George Robert M Post | 1999 | Biological Psychiatry1999，，12： | 1 |
| 13 | Small ubiquin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor 显示文摘 | LAUREN D W BRENDA J I GIUSEPPINA N | 2003 | PNAS2003，100，： | 1 |
| 14 | ECG to identify individuals显示文摘 | STEVEN A I JOHN M I ANDREW C MARK D W BRENDA K W | 2005 | Pattern Recognition2005，38，： | 1 |
| 15 | 25 years of the WHO essential medicines lists: progress and challenges 显示文摘 | Richard L Brenda W Andy G | 2003 | Lan- cet2003，361，9370： | 1 |
| 16 | Laboratory and field evaluation of spinosad against the gypsy moth, Lyrnantria dispar 显示文摘 | Kevin W Wanner Blair V Helson and Brenda JHarris | 2000 | Pest Manag Sci2000，56，10： | 1 |
| 17 | 25 years of the WHO essential drug lists:progress and challenges显示文摘 | Richard L Brenda W Andy G | 2003 | Lancet2003，361，9370： | 1 |
| 18 | Flavonoid biosynthesis: 'new' functions for an 'old' pathway显示文摘 | BRENDA W S | 1996 | Plant Science1996，1，11： | 1 |
| 19 | Interim clinical outcomes in the collaborative initial glaucoma treatment study comparing initial treatment randomized to medications or surgery显示文摘 | Paul R Lichter David C Musch Brenda W Gillespie Kenneth E Guire Nancy K Janz Patricia A Wren M.P.H.Richard P Mills | 2001 | Ophthalmology2001，，11： | 1 |
| 20 | Analysis of Flavanone 3-Hydroxylase in Arabidopsis Seedlings显示文摘 | Matthew K Pelletier Brenda W Shirley | 1996 | Plant Physiol1996，111，： | 1 |
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