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| 1 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 2 | Evolution of regoliths and landscapes in deeply weathered terrain-implications for geochemical exploration显示文摘 | BUTT C R M LINTERN M J ANAND R R | 2000 | Ore Geology Reviews2000，16，34： | 1 |
| 3 | Measuring electrostatic, van der Waals, and hydration forces in electrolyte solutions with an atomic force microscope 显示文摘 | Butt H J | 1991 | Biophysical Journal1991，60，： | 1 |
| 4 | Hydrodynamic force measurements:boundary slip of water on hydrophilic surfaces and electrokinetic effects显示文摘 | Bonaccurso E Kappl M Butt H J | 2002 | Physical Review Letters2002，88，07： | 1 |
| 5 | Aggregation Behavior of Aqueous Solutions of Ionic Liquid显示文摘 | Bowers James Butts C P Martin P J | 2004 | Langmuir2004，20，： | 1 |
| 6 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 7 | Progesterone regulation of uterine dendritic cell function in rodents is dependent on the stage of estrous cycle 显示文摘 | Butts CL Candando KM Warfel J | 2010 | Mucosal Immunol2010，3，5： | 1 |
| 8 | Exploiting drug-disease relationships for computational drug repositioning显示文摘 | Dudley J T Deshpande T Butte A J | 2011 | Briefings in bioinformatics2011，，： | 1 |
| 9 | Resistance to crown rot in wheat identified through an improved method for screening adult plants 显示文摘 | Wallwork H Butt M Cheong J P E | 2004 | Australasian Plant Pathology2004，33，： | 1 |
| 10 | Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors显示文摘 | BUTTE M J HWANG P K MOBLEY W C | 1998 | Biochemistry1998，37，16： | 1 |
| 11 | Prevalence of anxiety and depression in osteoarthritis: use of the Hospital Anxiety and Depression Scale as a screening tool显示文摘 | Axford J Butt A Heron C | 2010 | Clin Rheumatol2010，29，11： | 1 |
| 12 | Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003显示文摘 | Butt K M Smith G J Chen H | 2005 | Journal of Clinical Microbiology2005，43，11： | 1 |
| 13 | Capecitabine/oxaliplatin, a safe and active first-line regimen for older patients metastatic colorectal cancer:post hoc analysis of a large phase 1I study显示文摘 | Twelves CJ Butts CA Cassidy J | 2005 | Clin Colorectal Cancer2005，5，2： | 1 |
| 14 | Comparison between prostaglandin E1 and epoprostenol (prostacyclin) in infants after heart surgery 显示文摘 | Kermode J Butt W Shann F | 1991 | Br Heart J1991，66，： | 1 |
| 15 | Comparison of dynamic hip screw and gamma nail: a prospective, randomized, controlled trial显示文摘 | Butt MS Krikler S J Nafie S | 1995 | Injury1995，26，9： | 1 |
| 16 | The Laplacian pyramid as a com- pact image code显示文摘 | Butt P J Adelson E H | 1983 | IEEE Transactions on Commune1983，4，31： | 1 |
| 17 | Cellular toxicity associated with exposure to perfluorinated carboxylates (PFCAs) and their metabolic precursors显示文摘 | Rand A A Rooney J P Butt C M | 2014 | Chemical Research in Toxicology2014，27，： | 1 |
| 18 | A Multiresolution Spline with Ap- plication to Image Mosaics 显示文摘 | Butt P J Adelson E H | 1983 | ACM Transactions on Graphics1983，2，4： | 1 |
| 19 | Particle size, particle size distribution and related measurements of supported metal catalyst显示文摘 | Matyi R J Schwartz L H Butt J B | 1987 | Catal Rev Sci Eng1987，29，1： | 1 |
| 20 | Physiological, anatomical and genetic identification of CPG neurons in the developing mammalian spinal cord显示文摘 | Kiehn O Butt S J | 2003 | Prog Neurobiol2003，70，4： | 1 |
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