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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green | 2005 | The Lancet . 2005 (9464)2005，，： | 2 |
| 3 | Influence of birth order, birth weight, colostrum and serum immunoglobulin G on neonatal piglet survival显示文摘Background: Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G (IgG). The birth order and weight of 745 piglets (from 75 litters) were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion. Results: Sow parity had a significant (P < 0.001) effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration (P < 0.05); however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear (P < 0.05) and quadratic effect (P < 0.05) on % survival. Piglets with 1,000 mg/dl serum IgG or less (n=24) had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl (n=247) had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect (P < 0.05). Piglets weighing 0.9 kg (n = 107) at birth had a 68% survival rate, and those weighing 1.6 kg (n = 158) had an 89% survival. Conclusion: We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning. | Rafael A Cabrera Xi Lin Joy M Campbell Adam J Moeser Jack Odle | 2013 | Journal of Animal Science and Biotechnology2013，4，2： | 2 |
| 4 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 5 | The role of chemokine in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules 显示文摘 | Warnock R A Campbell J J Drof M E | 2000 | J Exp Med2000，191，： | 2 |
| 6 | Fast ignition inertial fusion: An inroduction and preview显示文摘 | CAMPBELL E M FEEEMAN R R TANAKA K A | 2006 | Fusion Sci Technol2006，49，3： | 1 |
| 7 | Sequential extraction procedure for the speciation of parficuinte trace metals显示文摘 | TESSIER A CAMPBELL P G C BLSSOM M | 1979 | Anal Chem1979，51，7： | 1 |
| 8 | Sequential extraction procedure for the speciation of particulate trace metals 显示文摘 | TESSIER A CAMPBELL P G C BISSON M | 1979 | Anal Chem1979，51，7： | 1 |
| 9 | Role of stereotactic radiosurgery as a primary treatment option in the management of newly diagnosed multiple (3-6) intracranial metastases显示文摘 | Jawahar A Shaya M Campbell P | 2005 | Surg Neurol2005，64，3： | 1 |
| 10 | Sequential extraction procedure for the speciation of particulate trace metals显示文摘 | TESSIER A CAMPBELL P G C BLSSON M | 1979 | Analytical Chemistry1979，51，7： | 1 |
| 11 | In vitro techniques for the assessment of neurotoxicity 显示文摘 | Harry GJ Billingsley M Bruinink A Campbell IL Classen W Dorman DC | 1998 | Environ Health Perspect1998，106，1： | 1 |
| 12 | Support Vector Machines Using GMM Supervectors forSpeaker Verification显示文摘 | CAMPBELL W M STURIM D E REYNOLDS D A | 2006 | IEEE Signal Processing Letters2006，13，5： | 1 |
| 13 | Proteomic analysis of thepefitrophic matrix from the gut of the caterpillar Helicoverpa armigera显示文摘 | Campbel P M Cao A T Hines E R | 2008 | Insect Biochem Mol Biol2008，38，： | 1 |
| 14 | Competitive interactions between endogenous LTD and LTP in the hippoeampus underlie the storage of emo- tional memories and stress-induced amnesia 显示文摘 | Diamond D M Park C R Campbell A M Woodson J C | 2005 | Hip- pocampus2005，15，： | 1 |
| 15 | Support vector machines using GMM supervectors for speaker verification 显示文摘 | Campbell W M Sturim D E Reynolds D A | 2006 | IEEE Signal Processing Letters2006，13，： | 1 |
| 16 | Phosphorus clusters:synthesis in the gas-phase and possible cagelike and chain structures显示文摘 | Bulgakov A V Bobrenok O F Kosyakov V I Pzerov I Marine W Hed~n M Rohmund F Campbell E E B | | 0，，： | 1 |
| 17 | Increased tissue kallikrein levels in type 2 di- abetes显示文摘 | CAMPBELL DJ KLADIS A ZHANG Y JENKINS AJ PRIOR DL YH M | 2010 | Diabetologia2010，53，4： | 1 |
| 18 | Support vector machines using GMM supervectors for speaker verification显示文摘 | Campbell W M Sturim D E Reynolds D A | 2006 | IEEE Signal Processing Letters2006，13，5： | 1 |
| 19 | Sequential extraction procedure for the speciation of particulate trace metals显示文摘 | Campbell P G C Bisson M | 1979 | Anal Chem1979，51，： | 1 |
| 20 | Sequential extraction procedure for the speciation of particulate trace metals 显示文摘 | Tessier A Campbell P G C Bisson M | 1979 | Anal Chem1979，51，7： | 1 |
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