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85篇 您的检索式：作者名="CARSTEN G"

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	题名	作者	年代	出处	被引量
1	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate显示文摘Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play key roles in programming the epigenome and facilitating recruitment of additional regulatory factors during successive cell lineage specification and differentiation steps. Here we show that Isl1 acts as a pioneer factor driving cardiomyocyte lineage commitment by shaping the chromatin landscape of cardiac progenitor cells. Using an Isl1 hypomorphic mouse line which shows congenital heart defects, genome-wide profiling of Isl1 binding together with RNA- and ATAC-sequencing of cardiac progenitor cells and their derivatives, we uncover a regulatory network downstream of Isl1 that orchestrates cardiogenesis. Mechanistically, we show that Isl1 binds to compacted chromatin and works in concert with the Brg1-Baf60c-based SWI/SNF complex to promote permissive cardiac lineage-specific alterations in the chromatin landscape not only of genes with critical functions in cardiac progenitor cells, but also of cardiomyocyte structural genes that are highly expressed when Isl1 itself is no longer present. Thus, the Isl1/Brg1-Baf60c complex plays a crucial role in orchestrating proper cardiogenesis and in establishing epigenetic memory of cardiomyocyte fate commitment.	Rui Gao Xingqun Liang Sirisha Cheedipudi Julio Cordero Xue Jiang Qingquan Zhang Luca Caputo Stefan Günther Carsten Kuenne Yonggang Ren Shoumo Bhattacharya Xuejun Yuan Guillermo Barreto Yihan Chen Thomas Braun Sylvia M. Evans Yunfu Sun Gergana Dobreva	2019	Cell Research2019，29，6：	5
2	High-sensitive troponin T in chronic heart failure correlates with severity of symptoms, left ventricular dysfunction and prognosis independently from N-terminal pro-b-type natriuretic peptide显示文摘	Carsten G. Jungbauer Julia Riedlinger Stefan Buchner Christoph Birner Markus Resch Matthias Lubnow Kurt Debl Monika Buesing Hendrik Huedig Günter Riegger Andreas Luchner	2011	Clinical Chemistry and Laboratory Medicine2011，，11：	2
3	Generation of activated and antigen-specific T cells with cytotoxic activity after co-culture with dendritic cells显示文摘	Angela M Tim G Carsten Z	2002	Cancer immunol immunother2002，51，：	1
4	Multiobjective Output-Feedback Control Via LMI Optimization显示文摘	Carsten S Pascal G Mahmoud C	1997	IEEE Trans on Automatic Control1997，42，7：	1
5	Listening to Mozart may not enhance performance on the revised Minnesota paper form board test 显示文摘	CARSTENS C B HUSKINS E HOUNSHELL G W	1995	Psy- chol Rep1995，77，1：	1
6	Editor' s Choice : Review : Effects of land use on plant diversity : A global meta-anal- ysis 显示文摘	Katharina G Carsten F Dormann Anke S	2014	Journal of Applied Ecology2014，51，6：	1
7	Transport of insulin across rabbit nasal mucosa in vitro induced by dide- canoyl-1-α-phosphatidylcholine 显示文摘	Carstens S Danielsen G Guldhammer B	1993	Diabetes1993，42，：	1
8	Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls显示文摘	CARSTEN H PHILIPPE G PA'L W		0，，08：	1
9	Molecular investigation of lymph nodes in colon cancer patients using one‐step nucleic acid amplification (OSNA)显示文摘	Ulrich Güller Andreas Zettl Mathias Worni Igor Langer Daniela Cabalzar‐Wondberg Carsten T. Viehl Nicolas Demartines Markus Zuber	2012	Cancer2012，，24：	1
10	Hyperbranched polylactide copolymers 显示文摘	Holger F Carsten G	2006	Macromoleeules2006，39，：	1
11	Mechanisms of T-box gene function in the developing heart显示文摘	Franziska G Carsten R Andreas K	2011	Cardiovasc Res2011，91，2：	1
12	Rapid quantifi- cation of bile acids and their conjugates in serum by liquid chro- matography - tandem mass spectrometry 显示文摘	Scherer M Carsten Gnewuch C Schmitz G	2009	Journal of Chroma- tography B2009，877，30：	1
13	Influence of constant and variadle restraining force on spring back of TRIP700 and stainless steel grades 显示文摘	Carsten G Weseman A Jurgen	2002	Steel Research2002，73，67：	1
14	Quantitative assessment of molecular remission after high-dose therapy with autologous stern cell transplantation predicts long-term remission in mantle cell lymphoma 显示文摘	Christiane P Carsten S Stefan G	2006	Blood2006，107，6：	1
15	Association of mitochondrial function and feed efficiency in poultry and livestock species 显示文摘	Bottje W G Carstens G E	2009	J Anim Sci2009，87，14：	1
16	Silica nanoparticle modified with aminosilanes as carriers for plasmid DNA 显示文摘	Carsten K Mohammad S Elenore G	2000	Intern J of Pharmac2000，196，：	1
17	Current clinical and laboratory strategies to augment the efficacy of immunotherapy in multiple myeloma显示文摘	Marcus G Carsten Z Axel G	2001	Clin Cancer Res2001，7，8：	1
18	Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI显示文摘	Anne S?rensen David Peters Carsten Simonsen Michael Pedersen Brian Stausb?l‐Gr?n Ole Bjarne Christiansen G?ran Lingman Niels Uldbjerg	2012	Prenat Diagn2012，，2：	1
19	Angular distribution of light scattered by single biological cells and oriented particle agglomerates显示文摘	JORG N CARSTEN G ANDREAS H	2003	App Opt2003，42，31：	1
20	Treatment of dural sinus thrombosis using selective catheterization and urokinase显示文摘	Horowitz M Purdy P Unwin H Carstens G 3rd Greenlee R Hise J	1995	Ann Neurol1995，38，1：	1

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