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| 1 | Phenol- ic antioxidants identified by ESI-MS from yerba mate (llex paraguariensis) and green tea (Cameliasinensis) extracts 显示文摘 | Bastos D I-I Saldanha L A Catharino R R | 2007 | Molecules2007，12，3： | 1 |
| 2 | Man-in-the-barrel syndrome,a symmetrical prox-imal brachial amyotrophic diplegia related to motor neuron diseases:asurvey of nine cases显示文摘 | Orsini M Catharino AM | 2009 | Rev Assoc Med Bras2009，55，6： | 1 |
| 3 | Evolution of major phenolic components and radical scavenging activity of grape juices through concentration process and storage显示文摘 | GOLLICKE A P B CATHARINO R R DE SOUZA J C | 2009 | Food Chemistry2009，112，4： | 1 |
| 4 | Cloud point extraction applied to casein proteins of cow milk and their identification by mass spec- trometry显示文摘 | LOPES A S GARCIA J S CATHARINO R R | 2007 | Anal Chim Acta2007，590，： | 1 |
| 5 | On-line monitoring of stevioside sweetener hydrolysis to steviol in acidic aqueous solutions 显示文摘 | Catharino R R Santos L S | 2012 | Food Chemistry2012，133，4： | 1 |
| 6 | Aflatoxin screening by MALDI-TOF mass spectrometry显示文摘 | Ramos Catharino R de Azevedo Marques L Silva Santos L | 2005 | Analytical chemistry2005，77，24： | 1 |
| 7 | Structure of the murine unglycosylated IgG1 Fc fragment显示文摘 | Feige M J Nath S Catharino S R | 2009 | J Mol Biol2009，391，3： | 1 |
| 8 | Electrospray ionization mass spectrometry fingerprinting of whisky:Immediate proof of origin and authenticity显示文摘 | M(O)LLER J K S CATHARINO R R EBERLIN M N | | 0，，06： | 1 |
| 9 | Phenolic antioxidants i- dentified by ESI -MS fromYerba Mate (llex paraguariensis) and green tea ( Camelia sinensis) extracts 显示文摘 | Bastos DH Saldanha LA Catharino RR | 2007 | Molecules2007，12，3： | 1 |
| 10 | Carbon nanoparticles for gene transfection in eukaryotic cell lines显示文摘 | H. Zanin L.M. Hollanda H.J. Ceragioli M.S. Ferreira D. Machado M. Lancellotti R.R. Catharino V. Baranauskas A.O. Lobo | 2014 | Materials Science & Engineering C2014，，： | 1 |
| 11 | Man-in-the-barrel syndrome, a symmetrical proximal brachial amyotrophie diplegia related to motor neuron diseases: a survey of nine eases 显示文摘 | Orsini M Catharino AM Catharino FM | 2009 | Revista da Assoeiaeao Medica Brasileira2009，55，6： | 1 |
| 12 | Environmental and sea-level variations on the southeastern Brazilian coast during the late Holocene with comments on prehistoric human occupation 显示文摘 | Ybert J P Bissa W M Catharino E L M | 2003 | Palaeogeography Palaeoclimatology Palaeoecology2003，189，： | 1 |
| 13 | Metabolomics in chronic hepatitis C:Decoding fibrosis grading and underlying pathways显示文摘BACKGROUND Chronic Hepatitis C(CHC)affects 71 million people globally and leads to liver issues such as fibrosis,cirrhosis,cancer,and death.A better understanding and prognosis of liver involvement are vital to reduce morbidity and mortality.The accurate identification of the fibrosis stage is crucial for making treatment decisions and predicting outcomes.Tests used to grade fibrosis include histological analysis and imaging but have limitations.Blood markers such as molecular biomarkers can offer valuable insights into fibrosis.AIM To identify potential biomarkers that might stratify these lesions and add information about the molecular mechanisms involved in the disease.METHODS Plasma samples were collected from 46 patients with hepatitis C and classified into fibrosis grades F1(n=13),F2(n=12),F3(n=6),and F4(n=15).To ensure that the identified biomarkers were exclusive to liver lesions(CHC fibrosis),healthy volunteer participants(n=50)were also included.An untargeted metabolomic technique was used to analyze the plasma metabolites using mass spectrometry and database verification.Statistical analyses were performed to identify differential biomarkers among groups.RESULTS Six differential metabolites were identified in each grade of fibrosis.This six-metabolite profile was able to establish a clustering tendency in patients with the same grade of fibrosis;thus,they showed greater efficiency in discriminating grades.CONCLUSION This study suggests that some of the observed biomarkers,once validated,have the potential to be applied as prognostic biomarkers.Furthermore,it suggests that liquid biopsy analyses of plasma metabolites are a good source of molecular biomarkers capable of stratifying patients with CHC according to fibrosis grade. | Adriana Camargo Ferrasi Samara Vitória Granja Lima Aline Faria Galvani Jeany Delafiori Flavia Luísa Dias-Audibert Rodrigo Ramos Catharino Giovanni Faria Silva Roberta Rodrigues Praxedes Driele Bretones Santos Dayane Trevisan de Macedo Almeida Estela Oliveira Lima | 2023 | World Journal of Hepatology2023，15，11： | 1 |
| 14 | Evolution of major phenolic components and redical scavenging activity of grape juices through concentration precess and storage显示文摘 | Gollueeke APB Catharino RR Souza JC | 2009 | Food Chem2009，112，4： | 1 |
| 15 | Mass spectrometric evidence for a zinc-porphyrin complex as the red pigment in drycured Iberian and Parma ham显示文摘 | Moller J K S Adamsen C E Catharino R R | 2007 | Meat Science2007，，75： | 1 |
| 16 | On - line monitoring of stevioside sweetener hydrolysis to steviol in acidic aqueous solutions 显示文摘 | CATHARINO R R SANTOS L S | 2012 | Food Chemistry2012，133，： | 1 |
| 17 | Eleetrospray ionization mass spectrometry fingerprinting of essential oils: Spices from the Labiatae family 显示文摘 | MOLLERII J K S CATHARINO R R EBERLIN M N | 2007 | Food Chemistry2007，100，3： | 1 |
| 18 | Evolution of major phenolic components and radical scavenging activity of grape juices through concentration process and storage显示文摘 | Boiago G Andrea P Catharino R R | 2009 | Food Chemistry2009，112，4： | 1 |
| 19 | Flavour characterization of red wines by descriptive analysis and ESI mass spec- trometry显示文摘 | BIASOTO A C T CATHARINO R R SANVIDO G B | 2010 | Food Qttai Prefer2010，21，7： | 1 |
| 20 | Evolution of major phenolic components and radical scavenging activity of grape juices through concentration process and storage 显示文摘 | GOLLUCKE A P B CATHARINO R R SOUZA J C | 2009 | Food Chemistry2009，112，4： | 1 |
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