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9篇 您的检索式:作者名="CHAO Wendi"
    题名 作者 年代 出处 被引量
1Oceanic Island Basalts within the West Junggar Ophiolitic Mélanges: Petrogenetic and Tectonic Implications显示文摘Recently,we focused on the Darbut and Karamay ophiolitic mélanges in West Junggar of the Central Asian Orogenic Belt(CAOB,?engr et al.,1993;Windley et al.,2007;Xiao and Santosh,2014),and made much progress.This study was supported by the National Nature Science Foundation of China(No.41303027)and Special Fund for Basic Scientific Research of Central Colleges Project(No.2014G1271058).The achievements are illustrated as follows.YANG Gaoxue LI Yongjun TONG Lili LI Ganyu SHEN Rui CHAO Wendi 2015Acta Geologica Sinica(English Edition)2015,89,1:3
2CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis显示文摘Siddhartha Jaiswal Catriona H.M. Jamieson Wendy W. Pang Christopher Y. Park Mark P. Chao Ravindra Majeti David Traver Nico van Rooijen Irving L. Weissman 2009Cell2009,,2:2
3CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells显示文摘Ravindra Majeti Mark P. Chao Ash A. Alizadeh Wendy W. Pang Siddhartha Jaiswal Kenneth D. Gibbs Nico van Rooijen Irving L. Weissman 2009Cell2009,,2:2
4IGF2: Epigenetic regulation and role in development and disease显示文摘Wendy Chao Patricia A. D'Amore 2008Cytokine and Growth Factor Reviews2008,,2:1
5Brain-targeting,acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery显示文摘Stroke is the leading cause of death and disability.Currently,there is no effective pharmacological treatment for this disease,which can be partially attributed to the inability to efficiently deliver therapeutics to the brain.Here we report the development of natural compound-derived nanoparticles(NPs),which function both as a potent therapeutic agent for stroke treatment and as an efficient carrier for drug delivery to the ischemic brain.First,we screened a collection of natural nanomaterials and identified betulinic acid(BA)as one of the most potent antioxidants for stroke treatment.Next,we engineered BA NPs for preferential drug release in acidic ischemic tissue through chemically converting BA to betulinic amine(BAM)and for targeted drug delivery through surface conjugation of AMD3100,a CXCR4 antagonist.The resulting AMD3100-conjugated BAM NPs,or A-BAM NPs,were then assessed as a therapeutic agent for stroke treatment and as a carrier for delivery of NA1,a neuroprotective peptide.We show that intravenous administration of A-BAM NPs effectively improved recovery from stroke and its efficacy was further enhanced when NA1 was encapsulated.Due to their multifunctionality and significant efficacy,we anticipate that A-BAM NPs have the potential to be translated both as a therapeutic agent and as a drug carrier to improve the treatment of stroke.Shenqi Zhang Bin Peng Zeming Chen Jiang Yu Gang Deng Youmei Bao Chao Ma Fengyi Du Wendy C.Sheu W.Taylor Kimberly J.Marc Simard Daniel Coman Qianxue Chen Fahmeed Hyder Jiangbing Zhou Kevin N.Sheth 2022Bioactive Materials2022,7,10:1
6EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling显示文摘Chun-Ju Chang Jer-Yen Yang Weiya Xia Chun-Te Chen Xiaoming Xie Chi-Hong Chao Wendy A. Woodward Jung-Mao Hsu Gabriel N. Hortobagyi Mien-Chie Hung 2011Cancer Cell2011,,1:1
7New Discovery of Ca. 38 Ma Ultramafic–mafic Dyke Swarms in the Mitizi Area, Northwestern Tibetan Plateau显示文摘Objective The Tibetan Plateau, located in the eastern part of the Alpine Himalayan tectonic domain, is the youngest and the most spectacular of all continent-continent collisional belts in the world(Zhang et al., 2007;Xu et al., 2011;Zhu et al., 2012).CHAO Wendi WANG Zuopeng LI Xiaojun ZHOU Yanlong 2021Acta Geologica Sinica(English Edition)2021,95,4:0
8A New Discovery of Early Carboniferous Gabbros in the Southern Chinese Altai: Evidence for Ridge Subduction显示文摘Objective The Chinese Altai as a key part of the Central Asian Orogenic Belt is characterized by numerous outcrops of Paleozoic granitoids and minor mafic plutons (Fig. 1a). It is widely accepted that Devonian ridge subduction played an important role in the tectonic evolution of the Chinese Altai. However, Carboniferous magmatism related to ridge subduction has received little attention. Moreover。WANG Zuopeng LI Yongjun YANG Gaoxue ZHANG Yuling CHAO Wendi 2020Acta Geologica Sinica(English Edition)2020,94,4:0
9Analog ferroelectric domain-wall memories and synaptic devices integrated with Si substrates显示文摘Brain-inspired neuromorphic computing can overcome the energy and throughput limitations of traditional von Neumann-type computing systems,which requires analog updates of their artificial synaptic strengths for the best recognition performance and low energy consumption.Here,we report synaptic devices made from highly insulating ferroelectric LiNbO_(3)(LNO)thin films bonded to SiO_(2)/Si wafers.Through the creation/annihilation of periodically arrayed antiparallel domains within LNO nanocells,which are stimulated using positive/negative voltage pulses(synaptic plasticity),we can modulate the synaptic conductance linearly by controlling the number of the conducting domain walls.The multilevel conductance is nonvolatile and reproducible with negligible dispersion over 100 switching cycles,representing much better performance than that of random defect-based nonlinear memristors,which generally exhibit large-scale resistance dispersion.The simulation of a neuromorphic network using these LNO artificial synapses achieves 95.6%recognition accuracy for faces,thus approaching the theoretical yield of ideal neuromorphic computing devices.Chao Wang Tianyu Wang Wendi Zhang Jun Jiang Lin Chen Anquan Jiang 2022Nano Research2022,15,4:0
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