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	题名	作者	年代	出处	被引量
1	胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。	Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉叶鹏	2017	中华高血压杂志2017，25，9：	2
2	Recent advances in the chemistry and biology of naturally occurring antibiotics显示文摘	Nicolaou KC Chen JS Edmonds DJ	2009	Angew Chem lnt Ed Engl2009，48，：	1
3	Expression profiling using cD2 NA microarrays显示文摘	Duggan DJ Bittner M Chen Y	1999	Nat Genet1999，21，1：	1
4	Thetransfacet pedicle -sparing approach for thoracic disc removal: cadaveric morphometricanalysis and preliminary clinical experience 显示文摘	Stillerman CB Chen TC Diaz DJ	1995	J Neurosurg1995，83，：	1
5	Expression profiling using cDNA microarrays显示文摘	Duggan DJ Bittner M Chen Y	1999	Nat Genet1999，21，1：	1
6	Measurement of allantoin in urine and plasma by high-performance liquid chromatography with pre-column derivatization显示文摘	Chen XB Kyle DJ Orskov ER	1993	J Chromatogr1993，617，：	1
7	Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain显示文摘	Cua DJ Sherlock J Chen Y	2003	Nature2003，421，6924：	1
8	Role of DNA-PK in the cellular response to DNA double-strand breaks显示文摘	Burma S Chen DJ	2004	DNA Repair(Amst)2004，，：	1
9	Endothelial keratoplasty a simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block 显示文摘	Terry MA Shamie N Chen ES Hoar KL Friend DJ	2008	Ophthalmology2008，115，7：	1
10	Role of asymmetric dimethyarginine in homocysteine-induced apoptosis of vascular smoth muscle cells显示文摘	Yuan Q Jiang DJ Chen QQ	2007	Biochem Biophys Res Commun2007，356，4：	1
11	Effect of fatty acid chain length and thioesterification on the augmentation of expression of plasminogen activator inhibitor-1 显示文摘	CHEN Y SOBEL BE SCHEIDER DJ	2002	Nutr Metab Cardiovasc Dis2002，12，6：	1
12	Production of vascular endothelial growth factor by human tumors inhibits the function of dendrites cells显示文摘	Garlovich DJ Chen HL Girgis KR	1996	Nat Med1996，2，10：	1
13	Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases(KPC)resistance显示文摘	Chen LF Anderson DJ Paterson DL	2012	Infect Drug Resist2012，5，：	1
14	The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives显示文摘	Chen L Magliano DJ Zimmet PZ	2012	Nat Rev Endocrinol2012，8，4：	1
15	Endothelial cell loss after Descemet' s stripping endothelial keratoplasty in a large prospective series显示文摘	Terry MA Chen ES Shamie N Hoar KL Friend DJ	2008	Ophthalmology2008，115，3：	1
16	Is ulnar nerve transposition beneficial during open reduction internal fixation of distal humerus fractures 显示文摘	Chen RC Harris DJ Ledus S	2010	J Orthop Trauma2010，24，7：	1
17	Downregulation of caffeie acid 3-O-methyltransferase and caffeoyl CoA 30- methyltransferase in transgenic alfalfa: Impacts on lignin structure and implications for the biosynthesis of G and S lignin 显示文摘	GUO DJ CHEN F INOUE K	2001	Plant Cell2001，13，1：	1
18	Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain显示文摘	Cua DJ Sherlock J Chen Y	2003	Nature2003，421，：	1
19	Molecular epidemiology of cancer 显示文摘	Chen YC Hunter DJ	2005	CA Cancer J Clin2005，55，1：	1
20	Impact of donor age and year of transplantation on graft and patient survival following liver transplantation for hepatitis C virus显示文摘	Mutimer DJ Gunson B Chen J	2006	Transplantation2006，81，1：	1

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