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您的检索式：作者名="CHEN Dingxin"
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| 1 | Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients显示文摘Dear Editor,In 2019,a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was identified as the causative agent of Coronavirus Disease 2019(COVID-19).As of 8 June 2020,the World Health Organization(WHO)has reported 6,912,751 globally confirmed cases with 400,469 deaths.Although generally causes mild disease,SARS-CoV-2 infection can result in serious outcomes,including acute lung injury(ALI)and acute respiratory distress syndrome(ARDS),the leading cause of mortality in patients with comorbidities.Recent autopsy studies of COVID-19 patients revealed mononuclear infiltration and excessive production of mucus in the infected lung,especially in the damaged small airways and alveoli(Bian and Team,2020;Liu et al.,2020). | Jiangping He Shuijiang Cai Huijian Feng Baomei Cai Lihui Lin Yuanbang Mai Yinqiang Fan Airu Zhu Huang Huang Junjie Shi Dingxin Li' Yuanjie Wei Yueping Li Yingying Zhao’ Yuejun Pan He Liu Xiaoneng Mo Xi He Shangtao Cao FengYu Hu Jincun Zhao Jie Wang Nanshan Zhong Xinwen Chen Xilong Deng Jiekai Chen | 2020 | Protein & Cell2020，11，9： | 7 |
| 2 | Direct analysis method of^(14)C radioactivity concentration in urine samples显示文摘Objective:To establish a rapid analysis method for the activity concentration of carbon-14(14C)in urine,in order to estimate the internal dose of 14C exposure,and to protect the health of occupational population.Methods:Liquid scintillation counting(LSC)combined with the function of transformed spectral index of the external standard spectrum(tSIE)was used to measure the quenching level and counting rate,and the spiked urine samples with different shades of color were measured by LSC.After establishing the efficiency-quenching curve,the quenching correction and activity concentration analysis of the actual samples were carried out.Results:By LSC and the data fitting,the relationship between efficiency and quenching index could be represented using the equation y=0.0013x-0.0177(R^(2)=0.978).Three actual spiked samples were tested to verify this method,with recoveries of 97%,102%,and 89%,respectively.14C activity concentration of 4 actual urine samples were 0.12,0.11,0.10 and 0.08 Bq/mL,respectively,while the corresponding extended relative uncertainties were 0.0652,0.0929,0.0893 and 0.1043,respectively.Conclusion:The direct analysis method of 14C activity concentration in urine samples was established using LSC.The recovery of 14C activity concentration in urine samples showed that the proposed method had relatively high accuracy.By studying on the source of uncertainty,the uncertainty of the analysis results mainly came from the statistical error of LSC,and the uncertainty component of counting efficiency. | Xiao Ge Linlin Yan Qiang Xiong Fei Chen Jing Liang Zhen Zhang Hailan Yang Dingxin Long | 2022 | Radiation Medicine and Protection2022，3，1： | 0 |
| 3 | Improve Spatiotemporal Kriging with Magnitude and Direction Information in Variogram Construction显示文摘Magnitude information and direction information are utilized to improve the spatiotemporal Kriging method in the step of variogram construction. Basement of spatiotemporal variogram construction is to calculate vector distance between time slices, and space slices. Criterions of vector distance to spatiotemporal variogram construction is discussed, and a new vector distance model considering both magnitude and direction information is proposed. Case study using data from National Network of Geomagnetic Observatories of China is carried out for cross validation. Results illustrate that the proposed model performs better in analyzing in the statistics of Mean absolute error(MAE) and Mean square error(MSE). The accuracy of spatiotemporal Kriging interpolation is improved with such an operation in vector distance. | CHEN Dingxin LIU Daizhi LI Yihong MENG Liang YANG Xiaojun | 2016 | Chinese Journal of Electronics2016，25，3： | 0 |
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