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| 1 | CFD–DEM–CVD multi-physical field coupling model for simulating particle coating process in spout bed显示文摘Particle coating is a very important step in many industrial production processes as the particle coating layers may fix surfaces with unique advantages. Given the limitation and disadvantages of the existing simulation methods, a coupled CFD–DEM–CVD multi-physical field model for particle-coating simulations has been established taking into account the velocity field, temperature field, concentration field, and deposition model. In this model, gas behavior and chemical reactions are simulated in the CFD frame based on the conservation laws of mass, momentum, and energy. The particle behavior is simulated in the DEM frame based on the gas–solid interphase force model and contact force model. The deposition behavior is simulated in the CVD frame based on the particle movement–adhesion–deposition model. The coupled model can be implemented in Fluent-EDEM software with their user definition function and application programming interface. The particle coating process involving the pyrolysis of acetylene was investigated, and the effect of bed temperature and inlet gas velocity on deposition rate and coating efficiency were investigated based on the proposed model with adjustable deposition coefficients. Both the average deposition layer mass and the average deposition layer thickness were found to be proportional to the elapsed time and increased at the rate of about 1.05 × 10^-2 mg/s and 3.45 × 10^-4 mm/s, respectively, setting the inlet gas velocity to 11 m/s and bed temperature to 1680 K. A higher temperature and larger inlet gas velocity lead to a larger deposition rate, but the coating efficiency decreases because of limits imposed by the chemical reaction. At a bed temperature of 1280 K, the average deposition rate is 7.40 × 10?3 mg/s when the inlet gas velocity is set to 11 m/s, which is about double the deposition rate when the inlet gas velocity is set as 5 m/s. The proposed model can provide some guidance for the operating conditions and parameters design of the spouted bed in actual coating settings and can also be further developed as a basic model of mechanisms to integrate detailed information across multiple scales. | Malin Liu Meng Chen Tianjin Li Yaping Tang Rongzheng Liu Youlin Shao Bing Liu Jiaxing Chang | 2019 | Particuology2019,17,1: | 6 |
| 2 | A novel coated-particle design and fluidized-bed chemical vapor deposition preparation method for fuel-element identification in a nuclear reactor显示文摘 | Rongzheng Liu Malin Liu Youlin Shao Xiaotong Chen Jingtao Ma Bing Liu | 2017 | Particuology2017,15,2: | 3 |
| 3 | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity显示文摘Triple-negative breast cancer(TNBC)is the most challenging subtype of breast cancer.Various endeavor has been made to explore the molecular biology basis of TNBC.Herein,we reported a novel function of factor Kinectin 1(KTN1)as a carcinogenic promoter in TNBC.KTN1 expression in TNBC was increased compared with adjacent tissues or luminal or Her2 subtypes of breast cancer,and TNBC patients with high KTN1 expression have poor prognosis.In functional studies,knockdown of KTN1 inhibited the proliferation and invasiveness of TNBC both in vitro and in vivo,while overexpression of KTN1 promoted cancer cell proliferation and invasiveness.RNA-seq analysis revealed that the interaction of cytokine-cytokine receptor,particularly CXCL8 gene,was upregulated by KTN1,which was supported by the further experiments.CXCL8 depletion inhibited the tumorigenesis and progression of TNBC.Additionally,rescue experiments validated that KTN1-mediated cell growth acceleration in TNBC was dependent on CXCL8 both in vitro and in vivo.Furthermore,it was found that KTN1 enhanced the phosphorylation of NF-κB/p65 protein at Ser536 site,and specifically bound to NF-κB/p65 protein in the nucleus and cytoplasm of cells.Moreover,the transcription of CXCL8 gene was directly upregulated by the complex of KTN1 and NF-κB/p65 protein.Taken together,our results elucidated a novel mechanism of KTN1 gene in TNBC tumorigenesis and progression.KTN1 may be a potential molecular target for the development of TNBC treatment. | Lin Gao Shanze Chen Malin Hong Wenbin Zhou Bilan Wang Junying Qiu Jinquan Xia Pan Zhao Li Fu Jigang Wang Yong Dai Ni Xie Qinhe Yang Hsien-Da Huang Xiang Gao Chang Zou | 2021 | Signal Transduction and Targeted Therapy2021,6,8: | 2 |
| 4 | Numerical simulation of uranium tetrafluoride fluorination in a multistage spouted bed using the improved CFD-DEM chemical reaction model显示文摘A CFD-DEM reaction coupling model was established to simulate UF_(4) fluorination process,in which heat and mass transfer,heterogeneous chemical reaction,and particle shrinkage model were considered.The gas behavior was described by the conservation laws of mass,momentum,and energy.The solid phase is modeled with the discrete element method,considering the gas-solid interphase force,contact force,heat transfer,and chemical reaction models based on the discretized surface.Each particle can be individually tracked and associated with specific physical properties.The proposed CFD-DEM reaction coupling model based on particle shrinking reaction model with discretized surface was validated by the experimental and literature results at first.Then a multistage conical spouted bed was proposed and the process of UF_(4) fluoridation reaction in it was investigated.The fluidization characteristics and the con-centration distribution of gaseous products in the spouted bed with an extended gas velocity range were obtained and analyzed.In addition,the effects of different parameters,such as superficial gas velocity,temperature,fluorine concentration,on fluoridation rate and the fluorine conversion rate were inves-tigated based on the proposed CFD-DEM reaction coupling model.The results obtained in this work are beneficial for method development of the chemical reaction simulation research in particle scale using the CFD-DEM model,and useful for operation and equipment parameters design of the uranium tetra-fluoride fluorinate industrial process in the future. | Mofan Qiu Zhao Chen Lin Jiang Rongzhen Liu Yaping Tang Malin Liu | 2023 | Particuology2023,,4: | 1 |
| 5 | Evaluation of environmental efficiency in China using data envelopment analysis显示文摘 | Jiandong Chen Malin Song Long Xu | 2014 | Ecological Indicators2014,,: | 1 |
| 6 | Detecting anoma- lous insiders in collaborative information systems 显示文摘 | CHEN You NYEMBA S MALIN B | 2012 | IEEE Transaction Dependable and Secure Computing2012,9,3: | 1 |
| 7 | Varation in physician-patient discussionof breast reconstruction显示文摘 | Chen JY Malin J Ganz A | 2009 | J Gen Int Med2009,24,1: | 1 |
| 8 | Detecting anomalous insiders in collaborative information systems 显示文摘 | Chen Y Nyemba S Malin B | 2012 | IEEE Trans on Dependable and Secure Computing2012,9,3: | 1 |
| 9 | Mechanical properties and oxidation resistance of SiC f /CVI-SiC composites with PIP-SiC interphase显示文摘 | Donghai Ding Wancheng Zhou Fa Luo Malin Chen Dongmei Zhu | 2012 | Ceramics International2012,,5: | 1 |
| 10 | Dip-coating of boron nitride interphase and its effects on mechanical properties of SiC f /SiC composites显示文摘 | Donghai Ding Wancheng Zhou Fa Luo Malin Chen Dongmei Zhu | 2012 | Materials Science & Engineering A2012,,: | 1 |
| 11 | Dielectric and microwave absorbing properties of low power plasma sprayed Al 2 O 3 /Nb composite coatings显示文摘 | Liang Zhou Wancheng Zhou Malin Chen Fa Luo Dongmei Zhu | 2011 | Materials Science & Engineering B2011,,18: | 1 |
| 12 | Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer显示文摘 | Malin D Chen F Schiller C | 2011 | Clin Canc Res2011,17,15: | 1 |
| 13 | Synthesis and Electrochemical Properties of Highly Crystallized CuV2O6 Nanowires显示文摘 | HU Fang LI Malin WEI Yingjin DU Fei CHEN Gang WANG Chunzhong | 2015 | Chemical Research in Chinese Universities2015,31,5: | 1 |
| 14 | CFD-DEM-VDGM method for simulation of particle fluidization behavior in multi-ring inclined-hole spouted fluidized bed显示文摘The simulation of particle fluidization behavior in a complex geometry with a large number of particles is challenging owing to the complexity of unstructured computational grids and high computational intensity.In this study,a virtual dual-grid model(VDGM)is proposed to calculate the solid volume fraction in unstructured grids and speed up the calculation.The VDGM is coupled with a computational fluid dynamics-discrete element method model to simulate particle fluidization behavior in a multi-ring inclined-hole spouted fluidized bed with 4.2 million particles under a high temperature of 1423 K.A computational fluid dynamics-discrete element method-virtual dual-grid model(CFD-DEM-VDGM)coupling model is implemented based on commercial software Fluent and EDEM.The time step settings in Fluent and EDEM and the pattern of particle data transfer in Fluent are improved to speed up the calculation.It is discovered that the VDGM can calculate the solid volume fraction in unstructured grids of complex geometry and speed up the calculation effectively.The calculation speed increased by more than 10 times compared with that of the segmentation sampling method.The new pattern of particle data transfer in Fluent can reduce data transfer time by more than 90%.The fluidization behavior of 4.2 million high-density particles in the multi-ring inclined-hole spouted fluidized bed is obtained and analyzed in detail.The CFD-DEM-VDGM coupling method is validated for the bed expansion height and spouting cycle time in a spouted fluidized bed via experimental results. | Meng Chen Zhao Chen Ming Gong Yaping Tang Malin Liu | 2021 | Particuology2021,19,4: | 0 |
| 15 | Effect of Nonmagnetic Impurity Doped on the Structural and Magnetic Properties of Quasi-one-dimensional Antiferromagnet LiCuVO4显示文摘 | YANG Xu DU Fei BIE Xiaofei LI Malin ZHANG Rongyu WEI Yingjin WANG Chunzhong CHEN Gang | 2015 | Chemical Research in Chinese Universities2015,31,3: | 0 |
| 16 | Dielectric Properties of SiC_f/PyC/SiC Composites After Oxidation显示文摘In this paper,the SiC fiber-reinforced SiC matrix composites with a 0.15μm thick pyrocarbon interphase(noted as SiC/PyC/SiC) were prepared by chemical vapor infiltration(CVI).The SiCf/PyC/SiC were oxidized in air at950 'C for 50 h.The dielectric properties after this high temperature oxidation were investigated in X-band from room temperature(RT) to 700℃.Results suggested that:ε′ of the SiC_f/PyC/SiC after oxidation increased at first then decreased with temperature elevating;ε″ increased with temperature raising in the temperature range studied. | SONG Huihui ZHOU Wancheng LUO Fa QING Yuchang CHEN Malin LI Zhimin | 2016 | Journal of the Chinese Ceramic Society2016,,2: | 0 |
| 17 | Light emission of heavily doped AlGaN structures under optical pumping显示文摘Spectral, temporal and polarization characteristics of spontaneous and stimulated luminescence of Al_(0.5)Ga_(0.5)N/AlN structures grown by molecular beam epitaxy were studied at the optical pulsed pumping with λ =266 nm. Samples with a high degree ofsilicon doping were investigated. The vast majority of radiation falls ontransitions within the band gap between the levels of defects. As a result, the radiation band embracing the wholevisible range of more than 300 THz is observed in both spontaneous radiation and induced luminescence. In spon-taneous radiation the band has a smooth spectral intensity distribution over the wavelengths, whereas induced radi-ation has its sharp peaks corresponding to the mode structure of the planar waveguide. The measured gain of the active medium is g≈70 cm^(-1) for a weak signal. | P. A. Bokhan N. V. Fateev I. V. Osinnykh T. V. Malin Dm. E. Zakrevsky K. S. Zhuravlev Xin Wei Jian Li Lianghui Chen | 2018 | Journal of Semiconductors2018,39,4: | 0 |