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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Excited - state properties of dioxorhenium(V) generation and reactivity of dioxorhenium(Ⅵ) 显示文摘 | Che C M Chung W C Lai T F | 1989 | Inorg Chem1989，28，： | 1 |
| 4 | Gelation of surimi by high hydrostatic pressure显示文摘 | Chung Y C Gebrehiwot A Farkas D F Morrissey M T | 1994 | J Food Sci1994，59，52： | 1 |
| 5 | The nature and timing of crustal thickening in Southern Tibet:Geochemical and zircon Hf isotopic constraints from postcollisional adakites显示文摘 | Chung S L Chu M F Ji J | 2009 | Tectonophysics2009，477，1： | 1 |
| 6 | Electrical conduction of anisotropic conductive adhesives:effect of size distribution of conducting filler particles 显示文摘 | Shi F G Abduuah M Chung paiboon patana S | 1999 | Mater Sci Semicond Pross1999，2，： | 1 |
| 7 | Three-stage full range stress-strain model for stainless steel 显示文摘 | Quach W M Teng J G Chung K F | 2008 | Journal o J Structural Engineering2008，134，9： | 1 |
| 8 | Physically crosslinked alginate/N,O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs 显示文摘 | Lin Y H Liang H F Chung C K Chen M C Sung H W | 2005 | Biomaterials2005，26，14： | 1 |
| 9 | Residual stresses in press-braked stainless steel sections I:Coiling and uncoiling of sheets显示文摘 | Quach W M Teng J G Chung K F | 2009 | Journal of Constructional Steel Research2009，65，18： | 1 |
| 10 | Fuzzy sliding mode controller design for uncertain time-delayed systems with nonlinear input显示文摘 | YU F M CHUNG H Y CHEN S Y | 2003 | Fuzzy Sets and Systems2003，140，2： | 1 |
| 11 | Simplified design of composit beams with large Web Openings to Eureeode 4 显示文摘 | Chung K F Lawson R M | 2001 | Journal of Construction Steel Research2001，57，： | 1 |
| 12 | Multiple sources for the origin of granites: Geochemical and Nd/Sr isotopic evidence from the Gudaoling granite and its mafic enclaves, northeast China显示文摘 | Yang J H Wu F Y Chung S L Wilde S A Chu M F | 2004 | Geochim Cosmochim Acta2004，68，44： | 1 |
| 13 | Adakites from continental collision zones: Melting of thickened lower crust beneath southern Tibet 显示文摘 | Chung S L Liu D Y Ji J Q Chu M F Lee H Y Wen D J Lo C H Lee T Y Qian Q Zhang Q | 2003 | Geology2003，31，11： | 1 |
| 14 | Simplified design of composite beams with large web openings to Eurocode 4显示文摘 | Chung K F Lawson R M | 2001 | Journal of Constructional Steel Research2001，114，3： | 1 |
| 15 | Zircon U-Pb and Hf iso- tope constraints on the Mesozoic tectonics and crustal evolu- tion of southern Tibet显示文摘 | Chu M F Chung S L Song B | 2006 | Geology2006，34，9： | 1 |
| 16 | Relationship of Nurses' Spirituality to Their Understanding and Practice of Spiritual Care显示文摘 | Chung L Y Wong F K Chan M F | 2007 | J Adv Nurs2007，58，2： | 1 |
| 17 | Sirtl promotes fat mobilization in white adipoeytes by repressing PPAR gamma显示文摘 | F Picard M Kurtev N Chung | 2004 | Nature2004，429，6993： | 1 |
| 18 | Self-regulating fuzzy control for forward DC-DC converters using an 8-bit microcontroller 显示文摘 | Hsu C F Chung I F Lin C M | 2009 | lET Power Electonics2009，2，1： | 1 |
| 19 | Combination roles of spatial geoscience data formineral exploration 显示文摘 | Chung C F Moon W M | 1991 | Geoinformatics1991，2，： | 1 |
| 20 | Sirtl promotes fat mobilization in white adipocytes by repressing PPAR - gamma 显示文摘 | Picard F Kurtev M Chung N | 2004 | Nature2004，429，6993： | 1 |
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