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| 1 | 麻醉剂丁香酚对黄腊鯵耗氧的影响显示文摘用不同浓度的丁香酚对体质量为115~175g的黄腊鯵(Trachinotus blochii)麻醉处理15 min,每1分钟测定容器内的氧饱和度1次。实验结果表明,黄腊?的耗氧率明显地受到丁香酚的影响,在各处理组中以10×10^(-6)浓度组的耗氧率为最低(0.33 mg/(g·h)),5×10^(-6)浓度组次之(0.42mg/(g·h)),而对照组则较高(0.57 mg/(g·h))。同时实验还表明经丁香酚麻醉处理的黄腊鯵鳃活动频率显著地比对照组低。此结果表明了在施用麻醉剂以后,鱼体的活动及对氧气的消耗有明显的下降,丁香酚可以作为活鱼运输过程中有效的麻醉剂。 | 张朝晖 丛娇日 王波 洪旭光 KjellφMidling | 2003 | 海洋科学2003,27,6: | 61 |
| 2 | 北欧湖泊的重金属调查:浓度、地理模式及与临界界限的关系显示文摘1995年秋天,北欧各国同时对本国的湖泊进行了调查,包括俄罗斯西北的科拉半岛。在大约3000个湖泊中,被调查的11种金属(铅、镉、砷、锌、铜、镍、钴、铁、锰、铬、钒)一般浓度较低,并具有明确的地理模式。对于铅、镉、锌和一定程度上钴的分布,远程迁移的空气污染带来的直接和间接影响是最重要的因素。湖中总有机碳(TOC)浓度对于铁和锰,并在一定程度上对于砷、铬和钒是重要的。对于铜和镍,基岩地质概况是最重要的控制因素,但在科拉半岛很多冶炼厂周围地区是个例外,在那里由于当地空气传播的污染,湖泊中铜和镍的浓度很高。基岩和地表的地质概况对于控制砷、钴、铬和钒的浓度也是重要的因素。调查结果表明在北欧国家湖泊中重金属污染在区域尺度上是一个较轻微的生态问题。 | Brit Lisa Skjelkvle Tom Andersen Eirik Fjeld Jaakko Mannio Anders Wilander Kjell Johansson Jens Peder Jensen Tatyana Moiseenko 孙学飞 | 2001 | AMBIO-人类环境杂志2001,30,1: | 11 |
| 3 | Understanding Propagated Sensation along Meridians by Volume Transmission in Peripheral Tissue显示文摘沿着顶点(PSM ) 的宣传感觉是一种感觉在 acupoint 的刺激期间沿着顶点移动的现象。PSM 让外观在人之中 1.3% 评价并且有低速度的特征,去向折磨了地点并且被困难被解释由的物理压力堵住知道神经并且血传播。体积传播(vt ) 是在发生在细胞外的液体并且在脑髓的液体的中央神经系统的细胞间的通讯的一个普遍模式。充满的从来源的 vt 信号行动到经由导致慢的散开和传送对流(流动) 的精力坡度的目标房间,长距离和少得多空格。vt 隧道扩散与卷部分和扭曲的二个参数在细胞外的空格形成丛。一些实验沿着顶点显示出在邻近、远的 acupoints 之间的信息传播生气针的片断。这个过程是一在与 nonsynaptic 传播有关的外部神经终端之间跨刺激。某 neurotransmitters 或 neuropeptides 象 glutamate,腺苷 triphosphate (ATP ) 和象物质 P, neurokinin A 和 calcitonin 那样的 neuropeptide 那样基因相关的肽联系与跨刺激当 vt 发信号,它能是问候。比较 PSM 和 vt 的特征,许多类似的方面能被发现导致 PSM 是在沿着顶点的外部织物的 vt 的一个过程的一个假设。vt 信号沿着顶点播送的原因是顶点富于在试验性地被证明了的低水力的抵抗的条件下面的空隙的液体。根据 descript 的 Darcys 法律空隙的液体和保存方程的流动,空隙的液体将向顶点移动并且沿着在隧道以内限制 vt 信号并且根据 Ficks 散开法律加速流动的顶点流动。在这个过程期间,从桅杆房间的组织安的 degranulation 在能膨胀的线路上发生毛状并且增加已经被观察了的血灌注和空隙的液体。PSM 的机制被其他的轴突反射展示(相连的传播, WT ) 并且在沿着顶点的外部织物的 vt,同时送一个连续可感觉的信号控制能被看上去象的神经系统 PSM。 | 张维波 赵晏 Kjell Fuxe | 2013 | Chinese Journal of Integrative Medicine2013,19,5: | 9 |
| 4 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 5 | 美国Haynesville页岩气井产量递减规律显示文摘Haynesville区块是美国含气量最丰富的页岩区块之一,地位重要,且数据相对完善,对其进行产量递减规律研究,既有现实意义,又有理论价值。同时运用传统Arps双曲递减模型和现代扩展指数递减模型对该区块2008—2014年812口页岩气单井产量进行拟合,分析递减模型的参数、峰值产量、不同时期递减率和最终可采储量,进而总结页岩气井的产量递减规律。结果表明:(1)该地区大部分页岩气井显示出典型的'钟型曲线'产量变化模式,即产量在短时期内从低到高达到峰值,然后迅速下降,并长期保持低产;(2)在递减阶段,两个模型对页岩气井组均值和单井产量数据序列都有很好的拟合效果,尽管传统的双曲递减模型的参数β有26%的取值大于l,但合理选取页岩气井的产气生命周期长度(比如20年)可有效降低最终可采储量预测误差,因此仍可用于页岩气产量分析;(3)约有70%的页岩气井峰值产量达到9.3万~27.9万m3/d,且从整体趋势看,'新井'往往比'老井'具有更高的峰值产量,递减期第1年时的产量递减率为72%,第2年时为86%。 | 郭克强 张宝生 Mikael HK Kjell ALEKLETT | 2016 | 石油科学通报2016,1,2: | 6 |
| 6 | Survival and an overview of decision-making in patients with cholangiocarcinoma显示文摘BACKGROUND:Cholangiocarcinoma is rare,accounting for approximately 3%of all gastrointestinal cancers.This study aimed to identify the survival rate among surgically treated and palliated patients,and secondly to identify parameters that could predict a curative resection. METHODS:A total of 121 patients,55 men and 66 women, median age 70 years(range 31-91),who had been treated for cholangiocarcinoma in the period of 1990-2005 were evaluated retrospectively. RESULTS:Curative resection was performed in 40 patients (33%),whereas 81 received palliative treatment(67%).16% (19 of 121)of the patients had an explorative laparotomy without tumour resection.Age above 65 years(OR 3.4;95% CI 1.4-8.4;P=0.008),weight loss(OR 8.5;95%CI 1.5-46; P=0.01)or tumour location(The resection rate of hilar cholangiocarcinoma was lower than that of intrapancreatic cancer.)(OR 2.7;95%CI 1.7-4.5;P=0.001)predicted palliative treatment.The adjusted 5-year survival rate of patients who received tumour resection and palliative treatment was 30%and 1.2%,respectively(P<0.001).The survival rate of patients who were subjected to hepatectomy (70%)was better than that of patients who had a local or distal resection(20%)(P=0.02). CONCLUSIONS:In few patients with a resectable cholangiocarcinoma,an explorative laparotomy is often necessary to evaluate resectability.However,long-term survival is significantly better in patients who received radical surgical resection. | Hvard Mjφrud Forsmo Arild Horn Asgaut Viste Dag Hoem Kjell φvrebφ | 2008 | Hepatobiliary & Pancreatic Diseases International2008,7,4: | 6 |
| 7 | Volume Transmission and Its Different Forms in the Central Nervous System显示文摘卷传播(vt ) 是发生在细胞外的液体(ECF ) 并且在大脑的脑髓的液体(CSF ) , vt 信号经由导致散开和传送对流(流动) 的精力坡度从来源搬到目标房间的细胞间的通讯的一个普遍模式。, vt 隧道在配线传播(WT ) 是弥漫的在细胞外的空格形成丛隧道(轴突,终端) 是秘密的。速度是慢的(秒分钟) 在 vt 当时在在 WT 的毫秒范围快速。细胞外的空间是为 vt 的底层,它被细胞外的矩阵调制。Extrasynaptic vt 被连接到 synaptic 传播并且经常多半与到达 pre 的 extrasynaptic 领域的 synaptic 传输器由于不完全的散开障碍发生 -- 并且触处, astroglia,和甚至邻近的触处的 post-synaptic 膜。指示为多巴胺(DA ) 的 striatal 象 D2 一样调停受体的 extrasynaptic 形式的存在存在在在在人的 striatum 的 vivo 的本地电路水平的 vt。经由 vt 能在位于导致 Ca2+ 的 astroglia 的 extrasynaptic metabotropic glutamate 受体上扮演的 extrasynaptic 的 Synaptic glutamate 调停了 astrocytic glutamate 版本直到细胞外的空间(ECS ) 。长距离肽 vt 和 CSF vt 非常是有距离的主要长距离 vt 在 CSF 的 1 公里和流动。为贝它内啡肽和后叶催产素的长距离 vt 的指示被获得。我们建议在女大草原田鼠的单配偶可以通过后叶催产素 vt 的增加发生,特别在原子核 accumbens。在中央神经系统(CNS ) 从细胞的网络包含受体,蛋白质, RNA 和 mtDNA 进 ECF 和 CSF 的细胞外的泡的版本可以是在 CNS 的基本通讯。它代表体积传播的一种特殊形式, vt 的 Roamer 子类型。它可以极大地在蛋白质 conformational 混乱贡献 synaptic 粘性而且到病理学的蛋白质的传播的动态事件。vt 也发生在外部神经系统和联系房间。短、长的距离 vt 可以在空隙的液体经由散开和流动发生在顶点隧道。针灸能由免除传输器和调节的人神经终端和桅杆房间生产 vt 信号。 | Kjell Fuxe Dasiel O.Borroto-Escuela Wilber Romero-Fernandez 张维波 Luigi F.Agnati | 2013 | Chinese Journal of Integrative Medicine2013,19,5: | 6 |
| 8 | 中国大油田的发展历程与展望(英文)显示文摘中国国内超过70%的原油产量来自于9个大油田。掌握这些油田的动态对于了解中国国内原油产量和未来中国原油进口需求是必要的。该研究利用递减曲线和采油速度分析,得出中国大油田未来产量的走势。研究表明,中国国内未来原油产量将会面临一个巨大的挑战,而这正是由大油田的成熟和递减引起的。证据也表明,水驱和提高采收率方法的大规模运用将会掩盖日益严重的资源缺乏,并可能会导致油田未来递减率比目前所见到的递减率更大。中国石油工业已经设法使其国内大油田的产量在几十年内保持稳定,但任何措施都无法阻止这些油田最终走向递减,且中国许多大油田已经过了峰值产量期进入递减。笔者认为,在未来几十年里,中国大油田的原油产量将大幅降低。 | Mikael Hk 唐旭 庞雄奇 Kjell Aleklett | 2010 | 石油勘探与开发2010,37,2: | 5 |
| 9 | Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma显示文摘Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSCLC)risk,biological mechanisms of these variants remain largely unknown.By integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility variants.We identified 3064 credible risk variants for NSCLC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive sites.Transcription factor enrichment analysis revealed that USF1 was AD-specific while CREB1 was SqCC-specific.Functional annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency related.Our results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSCLC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments. | Na Qin Yuancheng Li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen Lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa Landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete Loic Le Marchand Olle Melander Hans Brunnstrom Geoffrey Liu Rayjean JHung Angeline Andrew Lambertus AKiemeney Shan Zienolddiny Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip Lazarus Matthew BSchabath Melinda CAldrich Victoria LStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen | 2021 | Frontiers of Medicine2021,15,2: | 3 |
| 10 | ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, Midgut, Hindgut, and Unknown Primary显示文摘 | Pavel Marianne Baudin Eric Couvelard Anne Krenning Eric ?berg Kjell Steinmüller Thomas Anlauf Martin Wiedenmann Bertram Salazar Ramon | 2012 | Neuroendocrinology2012,,2: | 3 |
| 11 | Combining population genomics and ecological niche modeling to assess taxon limits between Carex jemtlandica and C. lepidocarpa显示文摘Carex section Ceratocystis(Cyperaceae)is a group of recently evolved plant species,in which hybridization is frequent,introgression is documented,taxonomy is complex,and morphological boundaries are vague.Within this section,a unified taxonomic treatment of the Carex jemtlandica-Carex lepidocarpa species complex does not exist,and Norway may currently be the sole country accepting species rank for both.Carex jemtlandica is mainly confined to Fennoscandia and is thus a Fennoscandian conservation responsibility.This motivated us to test the principal hypothesis that both C jemtlandica and C lepidocarpa represent evolutionary significant units,and that both deserve their current recognition at species level.We investigated their evolutionary distinctiveness in Norway,using restriction site-associated DNA sequencing and ecological niche modeling.Our genomic results reveal two genetic clusters,largely corresponding to C jemtlandica and C lepidocarpa that also remain distinct in sympatry,despite clear indications of ongoing hybridization and introgression.The ecological niche modeling suggests that they occupy different environmental niches.Jointly,our results clearly show that C.jemtlandica and C lepidocarpa represent separately evolving entities that should qualify recognition as evolutionary significant units.Given the high level of introgression compared to other hybridizing species pairs in Carex we recommend treating C jemtlandica as a subspecies of C lepidocarpa. | Malene Nygaard Petri Kemppainen James D.M.Speed Reidar Elven Kjell Ivar Flatberg Leif P.Galten Narjes Yousefi Heidi Solstad Mika Bendiksby | 2021 | Journal of Systematics and Evolution2021,59,4: | 3 |
| 12 | Intramedullary Nails Result in More Reoperations Than Sliding Hip Screws in Two-part Intertrochanteric Fractures显示文摘 | Kjell Matre Leif Ivar Havelin Jan-Erik Gjertsen Birgitte Espehaug Jonas Meling Fevang | 2013 | Clinical Orthopaedics and Related Research?2013,,4: | 3 |
| 13 | 陕西大荔县改水对氟牙症患病情况的影响显示文摘目的 观察陕西省大荔县龙门和皇都两村改水前后氟牙症的发病及流行情况 ,探讨改水对氟牙症发生的影响。方法 将 2 91名中小学生分为 2个组 ,①改水后组 :年龄 10~ 11岁 ,在改水1~ 2年以后出生 ,一直饮用含氟量为 1 2mg/L的新水源。②改水前组 ,年龄 15~ 16岁 ,在改水前4~ 5年出生 ,即在牙冠的形成发育期饮用 2 0~ 10 0mg/L的高氟水。根据Dean′s分类法记录受检者的牙齿情况。用t检验和 χ2 检验进行统计学分析。结果 ①改水前后两组的患病率分别为87 2 %和 4 8 8% ,改用新水源后 ,氟牙症的患病率下降了 38 4 % ,其中改水前组中到重度氟牙症患病率分别为 32 0 %和 8 8% ;改水后组为 13 9%和 0。流行指数由 2 11降为 1 0 1,差异有高度显著性(P =0 0 0 )。②改水前两村间的患病率分别为 90 7%和 82 0 % ,差异无显著性 ;改水后的患病率分别为 5 7 1%和 38 7%。龙门村高于皇都村 ,差异有显著性 (P =0 0 18)。③在各组之间 ,女性的患病率均高于男性 ,但差异无统计学意义。结论 ①改用含氟量为 1 2mg/L的水源后 ,明显降低了氟牙症的发生 ;② 1 2mg/L的水氟含量对大荔县人群来说仍然偏高 ,需要进一步采取措施 ,降低该地区饮水中氟的含量。 | 阮建平 刘忠岐 宋健玲 Kjell Bjorvatn 阮梅生 | 2004 | 中华口腔医学杂志2004,39,2: | 2 |
| 14 | 用植物油作为绝缘液降低变压器失火风险显示文摘每年,总有一些变压器发生故障导致火灾。由于变压器的绝缘液是可燃物,火灾可以持续数小时或数天。火、烟以及可能发生的液体泄漏,不仅会危及人体和动物健康,破坏环境,也会损毁邻近的设备。而且,此类事故会影响相关方的声誉和资产负债情况。因此,业内长期高度重视失火风险较低的变压器。ABB引进了高油酸、高燃点的天然酯绝缘液BIOTEMP,相比于传统使用的矿物油,BIOTEMP可极大地降低起火和火灾蔓延的风险。作为市场上最安全的变压器绝缘液之一,使用BIOTEMP的变压器究竟有何与众不同呢? | George Frimpong Stephane Page Kjell Carrander Don Cherry | 2014 | 电气制造2014,0,5: | 2 |
| 15 | 手术加^(125)I粒子永久性植入治疗肺癌单发脑转移瘤的临床疗效及放射性脑损伤程度的研究显示文摘背景与目的:研究证实全脑放射治疗可引起放射性脑损伤,因此,探索一条能取代全脑照射而不影响疗效的新的治疗方法十分必要。本研究的目的就是评价手术加125I粒子永久性组织间植入治疗非小细胞肺癌单发脑转移瘤的疗效及放射性脑损伤程度。方法:将67例非小细胞肺癌单发脑转移瘤随机分为:手术加125I粒子植入组(植入组)32例(47.8%);全脑加小野照射组(常规组)35例(52.2%)。所有患者均经病理证实为非小细胞肺癌,其中鳞癌42例,腺癌25例。CT或MRI证实67例患者颅内有转移灶且为单发。植入组行局部脑转移瘤切除术,术后根据肿瘤大小、部位、125I粒子排列距离和每粒粒子剂量大小确定插入粒子数量。粒子植入部位:在肿瘤切除部位及周围组织或手术区域肿瘤可能残存或复发部位。常规组先行全脑照射,2~3Gy/次,5次/周,照射至剂量为30~39Gy/3~4周后缩小野加量,总剂量达45~55Gy/5~6周。结果:植入组局控率、复发率、中位复发时间分别为96.9%、15.6%和9个月;常规组分别为82.9%、17.1%和7个月,两组比较均无统计学意义(P>0.05)。植入组的中位生存时间、1年生存率、1年死亡率分别为12个月、40.6%以及28.1%;常规组为9个月、31.4%以及37.1%,两组比较均有显著性差异(P<0.05)。植入组急性放射性反应明显轻于常规组。 | 王中敏 武静 王国朝 任俊丽 Drne Kjelle | 2002 | 癌症2002,21,10: | 2 |
| 16 | Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer显示文摘 | Mona Karlsson PhD Per Marits PhD Kjell Dahl PhD Tobias Dag?? MD Sven Enerb?ck Magnus Th?rn Ola Winqvist | 2010 | Annals of Surgical Oncology2010,,7: | 2 |
| 17 | Repositioning imatinib for spinal cord injury显示文摘Efforts to pharmacologically restore central nervous system(CNS)function after injury has historically focused on promoting nerve growth with nerve growth factors such as nerve growth factor(NGF),neurotrophin 3(NT3)and brain-derived neurotrophic factor(BDNF).However。 | Jacob Kjell Lars Olson | 2015 | Neural Regeneration Research2015,10,10: | 2 |
| 18 | Postoperative Instability After Decompression for Lumbar Spinal Stenosis显示文摘 | KARL-ERIK JOHNSSON STIG WILLNER KJELL JOHNSSON | 1986 | Spine1986,,2: | 2 |
| 19 | Pathogenesis of sciatic pain: role of herniated nucleus pulposus and deformation of spinal nerve root and dorsal root ganglion显示文摘 | Kjell Omarker Robert R. Myers | 1998 | Pain1998,,2: | 2 |
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