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| 1 | 【原创论文】不育夫妇中男方的代谢综合征与前列腺异常的情况显示文摘目前尚无年轻男性不育症患者代谢综合征与前列腺相关的症状和体征之间关系的系统研究。我们研究了171对不育夫妇中的男性(36.5±8.3岁),代谢综合征是根据国家胆固醇教育计划成人治疗专题小组第三次报告确定。所有人接受了激素(包括总睾酮和胰岛素)、精液f包括白细胞介素8,精浆中白细胞介素8(SIL-8))、阴囊及经直肠超声评估。因为我们此前已有大样本队列研究了不育男性代谢综合征和阴囊检测指标之间的相关性,这里我们重点研究代谢综合征与经直肠前列腺B超资料的相关性。前列腺相关症状采用美国国立卫生研究院评估慢性前列腺炎症状指数(NIH-CPSI)和国际前列腺症状评分(iPSS)。22位受试者符合代谢综合征的诊断标准。经年龄调整后的有序多项Logistic回归模型分析显示:胰岛素水平增加是代谢综合征的一个组分(Wald=29.5,P〈0.0001)并与TT负相关(调整后的r=0.359,P〈O.0001)。未观察到代谢综合征和NIH.CPSI或IPSS评分之间有相关性。经年龄、睾酮、胰岛素校正后有序多项Logistic回归模型显示:代谢综合征组分数目的增加与正常精子形态负相关(Wald=5.59,P〈0.02)、与前列腺炎症的分子标志物血清sIL-8水平正相关(Wald=4.32,P〈0.05),与前列腺总体积和移行带体积(Wald=17.6和12.5,P〈0.0001)、动脉收缩期峰值流速(Wald=9.57,P=0.002)、质地不均匀性(HR=8711.05—3.33],P〈0.05)、钙化灶大小(Wald=3.11,P〈0.05)正相关,但不与精囊体积或功能指标正相关。总之,不育夫妇中的男性代谢综合征与前列腺增大、生化指标(sIL8)和前列腺炎症的超声指标呈正相关,而与前列腺相关症状无正相关,表明代谢综合征可能是良性前列腺增生症的早期亚临床表现的触发点。 | Francesco Lotti Giovanni Corona Linda Vignozzi Matteo Rossi Elisa Maseroli Sarah Cipriani Mauro Gacci Gianni Forti Mario Maggi | 2014 | Asian Journal of Andrology2014，16，2： | 6 |
| 2 | Laser produced electromagnetic pulses: generation, detection and mitigation显示文摘This paper provides an up-to-date review of the problems related to the generation,detection and mitigation of strong electromagnetic pulses created in the interaction of high-power,high-energy laser pulses with different types of solid targets.It includes new experimental data obtained independently at several international laboratories.The mechanisms of electromagnetic field generation are analyzed and considered as a function of the intensity and the spectral range of emissions they produce.The major emphasis is put on the GHz frequency domain,which is the most damaging for electronics and may have important applications.The physics of electromagnetic emissions in other spectral domains,in particular THz and MHz,is also discussed.The theoretical models and numerical simulations are compared with the results of experimental measurements,with special attention to the methodology of measurements and complementary diagnostics.Understanding the underlying physical processes is the basis for developing techniques to mitigate the electromagnetic threat and to harness electromagnetic emissions,which may have promising applications. | Fabrizio Consoli Vladimir TTikhonchuk Matthieu Bardon Philip Bradford David CCarroll Jakub Cikhardt Mattia Cipriani Robert JClarke Thomas ECowan Colin NDanson Riccardo De Angelis Massimo De Marco Jean-Luc Dubois Bertr Etchessahar Alejro Laso Garcia David IHillier Ales Honsa Weiman Jiang Viliam Kmetik Josef Krása Yutong Li FredériéLubrano Paul McKenna Josefine Metzkes-Ng Alexre Poyé Irene Prencipe Piotr Ra¸czka Rol ASmith Roman Vrana Nigel CWoolsey Egle Zemaityte Yihang Zhang Zhe Zhang Bernhard Zielbauer David Neely | 2020 | High Power Laser Science and Engineering2020，8，2： | 3 |
| 3 | Acute renal injury after partial hepatectomy显示文摘Currently, partial hepatectomy is the treatment of choice for a wide variety of liver and biliary conditions. Among the possible complications of partial hepatectomy, acute kidney injury(AKI) should be considered as an important cause of increased morbidity and postoperative mortality. Difficulties in the data analysis related to postoperative AKI after liver resections are mainly due to the multiplicity of factors to be considered in the surgical patients, moreover, there is no consensus of the exact definition of AKI after liver resection in the literature, which hampers comparison and analysis of the scarce data published on the subject. Despite this multiplicity of risk factors for postoperative AKI after partial hepatectomy, there are main factors that clearly contribute to its occurrence. First factor relates to large blood losses with renal hypoperfusion during the operation, second factor relates to the occurrence of post-hepatectomy liver failure with consequent distributive circulatory changes and hepatorenal syndrome. Eventually, patients can have more than one factor contributing to post-operative AKI, and frequently these combinations of acute insults can be aggravated by sepsis or exposure to nephrotoxic drugs. | Luis Alberto Batista Peres Luis Cesar Bredt Raphael Flavio Fachini Cipriani | 2016 | World Journal of Hepatology2016，8，21： | 3 |
| 4 | An elastin-like recombinamer-based bioactive hydrogel embedded with mesenchymal stromal cells as an injectable scaffold for osteochondral repair显示文摘The aim of this study was to evaluate injectable,in situ cross-linkable elastin-like recombinamers(ELRs)for osteochondral repair.Both the ELR-based hydrogel alone and the ELR-based hydrogel embedded with rabbit mesenchymal stromal cells(rMSCs)were tested for the regeneration of critical subchondral defects in 10 New Zealand rabbits.Thus,cylindrical osteochondral defects were filled with an aqueous solution of ELRs and the animals sacrificed at 4months for histological and gross evaluation of features of biomaterial performance,including integration,cellular infiltration,surrounding matrix quality and the new matrix in the defects.Although both approaches helped cartilage regeneration,the results suggest that the specific composition of the rMSC-containing hydrogel permitted adequate bone regeneration,whereas the ELR-based hydrogel alone led to an excellent regeneration of hyaline cartilage.In conclusion,the ELR cross-linker solution can be easily delivered and forms a stable well-integrated hydrogel that supports infiltration and de novo matrix synthesis. | Filippo Cipriani Blanca Arino Palao Israel Gonzalez de Torre Aurelio Vega Castrillo Hector Jose Aguado Hernandez Matilde Alonso Rodrigo Angel Jose Alvarez Barcia Ana Sanchez Veronica Garcıa Diaz Monica Lopez Pena Jose Carlos Rodriguez-Cabello | 2019 | Regenerative Biomaterials2019，6，6： | 3 |
| 5 | Clinical epidemiology of chronic viral hepatitis B:A Tuscany real-world large-scale cohort study显示文摘AIM To build a regional database of chronic patients to define the clinical epidemiology of hepatitis B virus(HBV)-infected patients in the Tuscan public health care system.METHODS This study used a cross-sectional cohort design. We evaluated chronic viral hepatitis patients with HBV referred to the outpatient services of 16 hospital units. Information in the case report forms included main demographic data, blood chemistry data, viral hepatitis markers, instrumental evaluations, and eligibility for treatment or ongoing therapy and liver transplantation. RESULTS Of 4015 chronic viral hepatitis patients, 1096(27.3%) were HBV infected. The case report form was correctly completed for only 833 patients(64% males, 36% females; mean age 50.1 ± 15.4). Of these HBV-infected patients, 73% were Caucasian, 21% Asian, 4% Central African, 1% North African and 1% American. Stratifying patients by age and nationality, we found that 21.7% of HBV-infected patients were aged < 34 years(only 2.8% were Italian). The most represented routes of transmission were nosocomial/dental procedures(23%), mother-to-child(17%) and sexual transmission(12%). The most represented HBV genotypes were D(72%) and A(14%). Of the patients, 24.7% of patients were HBe Ag positive, and 75.3% were HBe Ag negative. Of the HBV patients 7% were anti-HDV positive. In the whole cohort, 26.9% were cirrhotic(35.8% aged < 45 years), and 47% were eligible for or currently undergoing treatment, of whom 41.9 % were cirrhotic. CONCLUSION Only 27.3% of chronic viral hepatitis patients were HBV infected. Our results provide evidence of HBV infection in people aged < 34 years, especially in the foreign population not protected by vaccination. In our cohort of patients, liver cirrhosis was also found in young adults. | Cristina Stasi Caterina Silvestri Roberto Berni Maurizia Rossana Brunetto Anna Linda Zignego Cristina Orsini Stefano Milani Liana Ricciardi Andrea De Luca Pierluigi Blanc Cesira Nencioni Donatella Aquilini Alessandro Bartoloni Giampaolo Bresci Santino Marchi Franco Filipponi Piero Colombatto Paolo Forte Andrea Galli Sauro Luchi Silvia Chigiotti Alessandro Nerli Giampaolo Corti Rodolfo Sacco Paola Carrai Angelo Ricchiuti Massimo Giusti Paolo Almi Andrea Cozzi Silvia Carloppi Giacomo Laffi Fabio Voller Francesco Cipriani | 2018 | World Journal of Hepatology2018，10，5： | 3 |
| 6 | Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature显示文摘肾的房间癌(RCC ) 是最普通的肾的肿瘤,为所有恶意的 2%-3% 的财务。尽管 RCC 被知道造血地传播,到胃的孤立的 RCC 转移是一个稀罕事件。在这篇文章,我们描述 RCC 的胃的复发 10 年以前与切除术和 interleukin-2 (IL-2 ) 对待的以后开发了 RCC 和 1 年的胰腺的复发的一个病人的临床的功课。积累的证据显示胰和胃的那变形参与应该与 RCC 的历史在任何病人被怀疑在 RCC 切除术和免疫疗法以后与胃肠的症状介绍甚至 10 年。 | Chiara Riviello Ilaria Tanini Greta Cipriani Pietro Pantaleo Carlo Nozzoli Alberto Poma Viligiardi Riccardo Andrea Valeri | 2006 | World Journal of Gastroenterology2006，12，32： | 2 |
| 7 | Hilar Cholangiocarcinoma: Preoperative Liver Optimization with Multidisciplinary Approach. Toward a Better Outcome显示文摘 | Francesca Ratti Federica Cipriani Fabio Ferla Marco Catena Michele Paganelli Luca A. M. Aldrighetti | 2013 | World Journal of Surgery2013，，6： | 2 |
| 8 | Acidic heteroxylans from medicinal plants and their anti-ulcer activity显示文摘 | Thales R. Cipriani Caroline G. Mellinger Lauro M. de Souza Cristiane H. Baggio Cristina S. Freitas Maria C.A. Marques Philip A.J. Gorin Guilherme L. Sassaki Marcello Iacomini | 2008 | Carbohydrate Polymers2008，，2： | 2 |
| 9 | A kiwifruit (Actinidia spp.) linkage map based on microsatellites and integrated with AFLP markers显示文摘 | R. Testolin W. G. Huang O. Lain R. Messina A. Vecchione G. Cipriani | 2001 | TAG Theoretical and Applied Genetics2001，，1： | 2 |
| 10 | AC/GT and AG/CT microsatellite repeat in peach:isolation,characterization and cross-species amplification in Prunus显示文摘 | Cipriani G Lot G Huang W G | 1999 | Theor Appl Genet1999，99，： | 1 |
| 11 | Hemorheological parameters in alopecia areata显示文摘 | Cipriani R Procidano M Seltarin P | 1995 | Folia Haematol Leipz1995，112，6： | 1 |
| 12 | Sertraline versusother antidepressive agents for depression 显示文摘 | Cipriani A La Ferla T Furukawa TA | 2010 | Cochrane Database Syst Rev2010，14，00： | 1 |
| 13 | Resistance gene analogs are candidate markers for disease-resistance genes in grape (Vitis spp.)显示文摘 | G. Di Gaspero G. Cipriani | 2002 | Theoretical and Applied Genetics2002，，1： | 1 |
| 14 | NK receptors, Sub- stance P, Anol expression and uhrastructural features of the muscle coat in Cav-I (-/-) mouse ileum 显示文摘 | Cipriani G Serboiu CS Gherghiceanu M | 2011 | J Cell Mol Med2011，15，11： | 1 |
| 15 | Urate : a novel biomarker of Parkinsong disease risk, diagnosis and prognosis 显示文摘 | Cipriani S Chen X Schwarzschild MA | 2010 | Biomark Med2010，4，5： | 1 |
| 16 | 前哨淋巴结活检对宫颈癌的作用:一种评论性的观点 | Angioli R. Palaia I. Cipriani C. P.B. Panici 侯巍 | 2005 | 世界核心医学期刊文摘(妇产科学分册)2005，0，6： | 1 |
| 17 | Intergeneration Transfer and Demographic Transition 显示文摘 | Blackburn Keith and Giam Pietro Cipriani | 2005 | Journal of Development Economics2005，78，： | 1 |
| 18 | Plasmaperfusion on trip tophan columns can imp rove the clinical outcome of patients affected with myasthenia gr avis显示文摘 | Lendiani G Cipriani S Passalacqua S | 2003 | Artif Cells Blood Substit Immobil Biotechnol2003，31，1： | 1 |
| 19 | A Bayesian approach to experimental analysis: trading in a laboratory financial market显示文摘 | Marco Cipriani Riccardo Costantini Antonio Guarino | 2012 | Review of Economic Design2012，，2： | 1 |
| 20 | Chitosan-alginate membranes accelerate wound healing 显示文摘 | Caetano GF Cipriani MA Moretti TA | 2015 | J Biomed Mater Res B Appl Biomater2015，103，5： | 1 |
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