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| 1 | 导致儿童期肥胖的生命早期危险因素:队列研究显示文摘目的确定早年(3岁以内)导致英国儿童肥胖的危险因素。设计前瞻性队列研究。方法Avon英国父母及儿童纵向调查研究。参与者参与队列研究的8234名年龄为7岁的儿童以及亚组的909名重点儿童,后者需额外提供与早期发育有关并涉及可能导致肥胖的各种资料。诊断标准7岁儿童体重指数≥95百分位确定为肥胖,参考1990年英国人口调查的诊断标准。结果经过最终验证,在假设的25项危险因素中有8项与肥胖有关:父母肥胖(父母双方校正后的相对危险度10.44,95%可信区间5.11~21.32);最早期(43个月内)的体重指数或体重反弹升高(校正后的相对危险度15.00,95%可信区间5.32~42.30);3岁时每周看电视的时间超过8小时(校正后的相对危险度1.55,95%可信区间1.13~2.12);追赶性生长(校正后的相对危险度2.60,95%可信区间1.09~6.16);8个月(校正后的相对危险度3.13,95%可信区间1.43~6.85)和18个月(校正后的相对危险度2.65,95%可信区间1.25~5.59)时体重的标准差值;1岁时体重增加值(校正后的相对危险度1.06,95%可信区间1.02~1.10,体重每增加100g);出生体重,每100g(校正后的相对危险度1.05,95%可信区间1.03~1.07);3岁时睡眠不足(<10.5小时,校正后的相对危险度1.45,95%可信区间1.10~1.89)。结论儿童期肥胖可能与8项危险因素有关。 | John J Reilly Julie Amstrong Ahmad R Dorosty Pauline M Emmett A Ness I Rogers Colin Steer Andrea Sherriff Children Study Team 冯凯 | 2005 | 英国医学杂志中文版2005，8，5： | 8 |
| 2 | Colonoscopy quality with Entonox? vs intravenous conscious sedation:18608 colonoscopy retrospective study显示文摘AIM To compare colonoscopy quality with nitrous oxide gas(Entonox?) against intravenous conscious sedation using midazolam plus opioid.METHODS A retrospective analysis was performed on a prospectively held database of 18608 colonoscopies carried out in Lothian health board hospitals between July 2013 and January 2016.The quality of colonoscopies performed with Entonox was compared to intravenous conscious sedation(abbreviated in this article as IVM).Furthermore,the quality of colonoscopies performed with an unmedicated group was compared to IVM.The study used the following key markers of colonoscopy quality:(1) patient comfort scores;(2) caecal intubation rates(CIRs); and (3) polyp detection rates (PDRs).We used binary logistic regression to model the data.RESULTS There was no difference in the rate of moderate-toextreme discomfort between the Entonox and IVM groups (17.9% vs 18.8%; OR = 1.06,95%CI: 0.95-1.18,P = 0.27).Patients in the unmedicated group were less likely to experience moderate-to-extreme discomfort than those in the IVM group(11.4% vs 18.8%; OR = 0.71,95%CI: 0.60-0.83,P < 0.001).There was no difference in caecal intubation between the Entonox and IVM groups(94.4% vs 93.7%; OR = 1.08,95%CI: 0.92-1.28,P = 0.34).There was no difference in caecal intubation between the unmedicated and IVM groups (94.2% vs 93.7%; OR = 0.98,95%CI: 0.79-1.22,P = 0.87).Polyp detection in the Entonox group was not different from IVM group (35.0% vs 33.1%; OR = 1.01,95%CI: 0.93-1.10,P = 0.79).Polyp detection in the unmedicated group was not significantly different from the IVM group (37.4% vs 33.1%; OR = 0.97,95%CI: 0.87-1.08,P = 0.60).CONCLUSION The use of Entonox was not associated with lower colonoscopy quality when compared to intravenous conscious sedation using midazolam plus opioid. | Alexander R Robertson Nicholas A Kennedy James A Robertson Nicholas I Church Colin L Noble | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 3 |
| 3 | Survey of background levels of PCDDs and PCDFs in UK soils显示文摘 | Colin S C Alwyn R F Ameera A H | 1989 | Chemosphere1989，18，16： | 1 |
| 4 | Nutrient additions generate prolific growth of Lyngbya majuscule (cyanobacteria) in field and bioassay experiments显示文摘 | KATHLEEN S A COLIN R A JAMES W U | 2007 | Harmful Algae2007，6，： | 1 |
| 5 | A biotic ligand model predicting acute copper toxicity for Daphnia magna : the effects of calcium,magnesium,sodium,potassium,and pH显示文摘 | KAREL A C COLIN R | 2002 | Environ Sci Technol2002，36，1： | 1 |
| 6 | In situ field experiment shows Lyngbya majuscula (cyanobacterium) growth stimulated by added iron,phosphorus and nitrogen显示文摘 | KATHLEEN S A COLIN R A JAMES W U | 2008 | Harmful Algae2008，7，： | 1 |
| 7 | Soil compaction : a review of past and present techniques for investigating effects on root growth显示文摘 | Saoirse R Tracy Colin R Black Jeremy A Roberts | 2011 | J Sci Food Agric2011，91，： | 1 |
| 8 | Features of autism spec- trum disorder (ASD) in childhood epilepsy : a population-based study 显示文摘 | COLIN R PATRICIA A KRISHNA B D | 2015 | Epi Behav2015，42，1： | 1 |
| 9 | Zea mays Annexins Modulate Cytosolic Free Ca^sup 2+^ and Generate a Ca^sup 2+^-Permeable Conductance(W)显示文摘 | Laohavisit Anuphon Mortimer Jennifer C Demidchik Vadim Coxon Katy M Stancombe Matthew A Macpherson Neil Brownlee Colin Hofmann Andreas Webb Alex A R Miedema Henk Battey Nicholas H Davies Julia M | 2009 | Plant Cell2009，，2： | 1 |
| 10 | The interaction of a baroclinic mean flow with long Rossby waves 显示文摘 | Colin de Verdiere Tailleux A R | 2005 | Journal of Physical Oceanography2005，35，： | 1 |
| 11 | In Search of a Functional Flora-towards a Greater Integration of Ecology and Taxonomy显示文摘 | PENDRY COLIN A DICK JAN PULLAN MARTIN R | 2007 | Plant Ecology2007，192，： | 1 |
| 12 | Primates and the e-cology of their infectious diseases:how will anthropogenic change affecthost-parasite interaction显示文摘 | CHAPMAN C A COLIN A GILLESPIE T R | 2005 | Evolutionary Anthropology2005，14，4： | 1 |
| 13 | Alpha - fetoprotein as an early predictor of adverse perinatal outcome 显示文摘 | Garcia- Cavazos R Colin -Valenzuela A Espinoy Sosa S | 2010 | Ginecol Obstet Mex2010，78，5： | 1 |
| 14 | The Economics of Electricity Hedging and a Proposed Modification for the Futures Contract for Electricity显示文摘 | Colins R A | 2002 | IEEE Trans on Power Systems2002，17，1： | 1 |
| 15 | Effect of a nutritionalintervention on body composition, clinical status, and quality of life inpatients with heart failure显示文摘 | Colin R E Castillo M L Orea T A | 2004 | Nutrition2004，20，10： | 1 |
| 16 | Surveying the nuclear caloric curve显示文摘 | Y.-G Ma A Siwek J Péter F Gulminelli R Dayras L Nalpas B Tamain E Vient G Auger Ch.O Bacri J Benlliure E Bisquer B Borderie R Bougault R Brou J.L Charvet A Chbihi J Colin D Cussol E De Filippo A Demeyer D Doré D Durand P Ecomard P Eudes E Gerlic D Gourio | 1997 | Physics Letters B1997，，1： | 1 |
| 17 | Levels and trends of brominaled flame retardants in the European environment 显示文摘 | ROBIN J I COLIN R A JACO B | 2006 | Chemosphere2006，64，： | 1 |
| 18 | Relation between negligent adverse events and the outcomes of medical-malpractice litigation 显示文摘 | Troyen A Brennan Colin M Sox Helen R Burstin | 1996 | The New England Journal of Medicine1996，335，26： | 1 |
| 19 | Antigenic and genetic characteristics of swine - origin 2009 A ( HI N1 ) influenza viruses circulating in humans 显示文摘 | REBECCA J G TODD C D COLIN A R | 2009 | Science2009，22，： | 1 |
| 20 | In situ field experiment shows lyngbya majuscula (cyanobacterium) growth stimulated by added iron, phosphorus and nitrogen 显示文摘 | Kathleen S A Colin R A James W U | 2008 | Harmful Algae2008，7，38： | 1 |
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