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| 1 | Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial显示文摘 | Ronald P DeMatteo Karla V Ballman Cristina R Antonescu Robert G Maki Peter WT Pisters George D Demetri Martin E Blackstein Charles D Blanke Margaret von Mehren Murray F Brennan Shreyaskumar Patel Martin D McCarter Jonathan A Polikoff Benjamin R Tan Kouros | 2009 | The Lancet2009，，9669： | 2 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 4 | Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site显示文摘 | Cristina RA Agres V Lisa S | 2004 | Clin Cancer Res2004，10，： | 1 |
| 5 | Volatile composition and descriptive sensory analysis of pomegranate juice and wine显示文摘 | Antonio J.Andreu-Sevillaa Pedro M Nuria M Cristina G V | | 0，，54： | 1 |
| 6 | Molecular dynamics simulation of cationic and anionic clays containing amino acids 显示文摘 | NEWMAN S P CRISTINA T D COVENEY P V | 2002 | Langmuir2002，18，： | 1 |
| 7 | Effect of heat and thermosoaication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale)显示文摘 | RUI M S C MARGARIDA C V CRISTINA L M S | 2006 | Journal of Food Engineering2006，72，： | 1 |
| 8 | Early management of severe traumatic brain injury显示文摘 | Jeffrey V Rosenfeld Andrew I Maas Peter Bragge M Cristina Morganti-Kossmann Geoffrey T Manley Russell L Gruen | 2012 | The Lancet2012，，9847： | 1 |
| 9 | Structural organization of the tight junctions显示文摘 | Luca P Laura Ti Cristina V | 2008 | Biochimicaet Biophysica Acta2008，177，8： | 1 |
| 10 | Molecular dynamics simulation of cationic and anionic clays containing amino acids显示文摘 | NEWMAN S P CRISTINA T D COVENEY P V | 2002 | Langmuir2002，18，： | 1 |
| 11 | Effects of germination on the nutritive value and bioactive compounds of brown rice breads显示文摘 | FABIOLA C PATRICIO J C CRISTINA M V | 2015 | Food Chem2015，173，： | 1 |
| 12 | Determination of eight nitrosamines in water at the ng·L^-1 levels by liquid chromatography coupled to atmospheric presure chemical ionization tandem mass spectrometry显示文摘 | CRISTINA R ELENA P JUAN V S | 2011 | Anal Chim Acta2011，702，： | 1 |
| 13 | Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development显示文摘 | Massimo Rizzi Carlo Perego Marisa Aliprandi Cristina Richichi Teresa Ravizza Daniele Colella Jana Velískǒvá Solomon L. Moshé M.Grazia De Simoni Annamaria Vezzani | 2003 | Neurobiology of Disease2003，，3： | 1 |
| 14 | Inhibition of PI3K induces Rac activation and membrane ruffling in proto-Dbl expressing cells显示文摘 | Cristina V Vineenzo V Patriza M | 2006 | Cell Cycle2006，22，5： | 1 |
| 15 | DNA damage induces transcriptional activation ofp73 by removing GEBPa repression on E2F1显示文摘 | Mirko M Faina V Cristina R | 2003 | Nucleic Acids Res2003，31，22： | 1 |
| 16 | G13 regulation of proto-Dbl signaling显示文摘 | Cristina V Patrizia M Ctherine O | 2007 | Cell Cycle2007，16，6： | 1 |
| 17 | Epidermal stem cells: an update 显示文摘 | Watt FM Lo Cristina C silva-Vargas V | 2006 | Curr Opin Genet Dev2006，16，5： | 1 |
| 18 | Determination of tetracycline residues in soil by pressurized liquid extraction and liquid chromatography tandem mass spectrometry显示文摘 | VICENTE A PABLO V R CRISTINA B YOLANDA P | 2009 | Anal Bioanal Chem2009，394，5： | 1 |
| 19 | Antioxidant activity of amaranth protein or their hydrolysates under simulated gastrointestinal digestion显示文摘 | ORSINI D M C TIRONI V A CRISTINA A M | 2011 | LWT-Food Science and Technology2011，44，8： | 1 |
| 20 | Activation of immunological responses in Litopenaeus setiferus hemocytes by a hemocyanin like-lectin显示文摘 | Juan Alpuche Carlos Rosas Lorena Vázquez Jorge Guevara Ali Pereyra Concepción Agundis Cristina Pascual Edgar Zenteno | 2009 | Aquaculture2009，，1： | 1 |
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