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| 1 | Optimization of dewatering schemes for a deep foundation pit near the Yangtze River, China显示文摘A deep foundation pit constructed for an underground transportation hub was excavated near the Yangtze River. Among the strata, there are two confined aquifers, between which lies an aquiclude that is partially missing. To guarantee the safety of pit excavation, the piezometric head of the upper confined aquifer, where the pit bottom is located, should be 1 m below the pit bottom, while that of the lower confined aquifer should be dewatered down to a safe water level to avoid uplift problem. The Yangtze River levee is notably close to the pit, and its deformation caused by dewatering should be controlled. A pumping test was performed to obtain the hydraulic conductivity of the upper confined aquifer. The average value of the hydraulic conductivity obtained from analytical calculation is 20.45 m/d, which is larger than the values from numerical simulation(horizontal hydraulic conductivity K_H = 16 m/d and vertical hydraulic conductivity K_V = S m/d). The difference between K_H and K_V indicates the anisotropy of the aquifer. Two dewatering schemes were designed for the construction and simulated by the numerical models for comparison purposes. The results show that though the first scheme could meet the dewatering requirements, the largest accumulated settlement and differential settlement would be94.64 mm and 3.3‰, respectively, greatly exceeding the limited values. Meanwhile, the second scheme,in which the bottoms of the waterproof curtains in ramp B and the river side of ramp A are installed at a deeper elevation of-28 m above sea level, and 27 recharge wells are set along the levee, can control the deformation of the levee significantly. | Yang You Changhong Yan Baotian Xu Shi Liu Canhui Che | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，3： | 3 |
| 2 | Finite Element Analysis of an Air Spring for Automobile Suspension显示文摘 | Yang Weimin Chen Canhui Chen Yaling | | 0，，01： | 1 |
| 3 | Finite Element Analysis of an Air Spring for Automobile Suspension显示文摘 | Yang Weimin Chen Canhui Chen Yaling | 2004 | Journal of Beijing University of Chemical Technology2004，，1： | 1 |
| 4 | Seven facts and five initiatives for gut microbiome research显示文摘The gut microbiome has attracted increasing attention over the past 15 years.Along with the fast-growing body of research literature and media reports,the public's opinions on the gut microbiome have begun to appear polarized.Some believe that the gut microbiome is at the core of human health and is related to every single disease.To the opposite,some people question the scientific basis of gut microbiome studies and criticize that many of them are farfetched;there is even a joke spreading in the biomedical research field—'keeping gut microbiome in mind,no mechanism is hard to find'. | Danyi Li Chunhui Gao Faming Zhang Ruifu Yang Canhui Lan Yonghui Ma Jun Wang | 2020 | Protein & Cell2020，11，6： | 1 |
| 5 | “Series and parallel” design of ether linkage and imidazolium cation synergistically regulated four-armed polymerized ionic liquid for all-solid-state polymer electrolyte显示文摘Developing all-solid-state polymer electrolytes(SPEs) with high electrochemical performances and stability is of great importance for exploiting of high energy density and safe batteries. Herein, ether linkage and imidazolium ionic liquid(ILs) are incorporated into the multi-armed polymer backbone though the series and parallel way. The parallel polymeric ionic liquid(P-P(PEGMA-IM)) maximizes the synergistic effect of ILs and ether linkage, which endowed the material with low crystallinity and high flame retardancy. The P-P(PEGMA-IM) based P-SPE presents a high ionic conductivity of 0.489 m S/cm at 60°C, an excellent lithium-ion transference number of 0.46 and a wide electrochemical window of 4.87 V.The assembled lithium metal battery using P-SPE can deliver a capacity of 151 m Ah/g at 0.2 C, and the capacity retention ratio reaches 82% with a columbic efficiency beyond 99%. The overpotential of P-SPE based symmetric battery is 0.08 V, and there is no apparent magnifying even after 130 h cycling. This new design provides a new avenue for exploitation of advanced SPEs for the next-generation batteries. | Zehui Xie Yang Zhou Canhui Ling Xinlin Zhu Zhao Fang Xiaolong Fu Wuwei Yan Yong Yang | 2022 | Chinese Chemical Letters2022，33，3： | 1 |
| 6 | Finite element analysis of an air spring for automobile suspension显示文摘 | YANG Weimin CHEN Canhui CHEN Yaling | 2004 | Journal of Beijing University of Chemical Technology2004，31，3： | 1 |
| 7 | Application of highlight removal and multivariate image analysis to color measurement of flotation bubble images显示文摘 | YANG Chunhua XU Canhui GUI Weihua | 2009 | International Journal of Image Systems and Technology2009，19，4： | 1 |
| 8 | Strengthening poly(2-hydroxyethyl methacrylate) hydrogels using biochars and hydrophobic aggregations显示文摘As the first version of synthetic hydrogel,poly(2-hydroxyethyl methacrylate)hydrogels have found broad applications.However,their poor mechanical performances have been longstanding hurdles for practical deployments.Herein,we report on strengthening the poly(2-hydroxyethyl methacrylate)hydro-gels with biochar nanoparticles and hydrophobic aggregations,which are induced by solvent exchange and reinforced by freeze-thaw.Both the vast anchoring points on the multifunc-tional surfaces of the biochar nanoparticles and the aggregates formed between poly(2-hydroxyethyl methacrylate)chains engender strong and dissipative physical crosslinks.The result-ing hydrogels exhibit marked mechanical properties,encom-passing high stretchability~7,high fracture toughness~1360 J m−2,high elastic modulus~180 kPa,low friction coefficient~0.2,self-recovery,and non-swellability.Furthermore,we demonstrate the versatility of the proposed strategy by using water/ionic liquid binary solvent as the sol-vent system,Laponite as the nano-reinforcement,and dryanneal as the hydrophobic aggregation enhancer to synthesize mechanically robust hydrogels.Poly(2-hydroxyethyl methacry-late)hydrogels of superior mechanical properties are expected to enable previously inaccessible applications in biomedicine and engineering. | Ping Zhang Ziyi Xu Zhiying Wu Ping Xu Canhui Yang | 2022 | International Journal of Smart and Nano Materials2022，13，4： | 1 |
| 9 | Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction显示文摘Ginsenoside Rb1 shows a strong antioxidant effect and has potential activation effects on Akt.The aim of the present study was to investigate the protective effect of Rb1 on age-related ovarian granulosa cell injury.Ovarian granulosa cells(GCs)were obtained from 50 young women(≤30 years)and 50 aged women(≥38 years)at an IVF center.Young and aged ICR mice were administered with or without Rb1(10 mg kg^(-1),i.p.)for 2 weeks.The protective effects of Rb1 were investigated and the role of Rb1 on the modulation of Akt-FoxO1 interaction was determined with immunofluorescence,Western blotting,immunoprecipitation,si RNA silencing and pharmacological inhibitor.Rb1 effectively decreased LDH and MDA,and reversed the apoptotic-related protein levels in h GL cells from old patients.Similar results were found in mice.In addition,the mitochondrial membrane potential was restored and the overaccumulation of ROS was reversed by Rb1.Rb1 preserved peroxide-impaired Akt activation,to some extent,by increasing phosphorylation at Ser473.Rb1 also facilitated p-Akt binding to FoxO1 and promoted the phosphorylation of FoxO1.Si RNA silencing of Akt,Akt inhibitor LY294002,and FoxO1 inhibitor AS1842856 attenuated the effects of Rb1.Ginsenoside Rb1 inhibits age-related GCs oxidative damage by activating Akt phosphorylation at Ser473 and by further interaction with FoxO1. | Ping Zhou Feng Deng Zi Yang Canhui Cao Hongcui Zhao Fenting Liu Ke Zhong Lin Fu Tianliu Peng Di Sun Hui Liu Rong Li Yang Yu | 2022 | Science China(Life Sciences)2022，65，11： | 1 |
| 10 | The DELLA-ABI4-HY5 module integrates light and gibberellin signals to regulate hypocotyl elongation显示文摘Plant growth is coordinately controlled by various environmental and hormonal signals,of which light and gibberellin(GA)signals are two critical factors with opposite effects on hypocotyl elongation.Although interactions between the light and GA signaling pathways have been studied extensively,the detailed regulatory mechanism of their direct crosstalk in hypocotyl elongation remains to be fully clarified.Previously,we reported that ABA INSENSITIVE 4(ABI4)controls hypocotyl elongation through its regulation of cellelongation-related genes,but whether it is also involved in GA signaling to promote hypocotyl elongation is unknown.In this study,we showthat promotion of hypocotyl elongation by GA is dependent on ABI4 activation.DELLAs interact directly with ABI4 and inhibit its DNA-binding activity.In turn,ABI4 combined with ELONGATED HYPOCOTYL 5(HY5),a key positive factor in light signaling,feedback regulates the expression of the GA2ox GA catabolism genes and thus modulates GA levels.Taken together,our results suggest that the DELLA-ABI4-HY5 module may serve as a molecular link that integrates GA and light signals to control hypocotyl elongation. | Haibo Xiong Dandan Lu Zhiyuan Li Jianghao Wu Xin Ning Weijun Lin Zechen Bai Canhui Zheng Yang Sun Wei Chi Lixin Zhang Xiumei Xu | 2023 | Plant Communications2023，4，5： | 0 |
| 11 | Evidence for existence of a close association between CD14 and CXCR4 on monocytic cell line U937显示文摘单核白血球上的 HIV-1 coreceptors (CXCR4 和 CCR5 ) 的表面表示能被房间的 CD14,和危险性的 ligand 调整到 HIV-1 然后被改变。我们的以前的学习发现对 CD14 的那单音的同种细胞的抗体能戏剧性地禁止药物治疗 CXCR4 的趋化性和房间房间熔化。把研究基于这些,我们在结合 lineFITC 的 anti-CD14 monocolnal 抗体(mAb ) 12G5 强烈禁止了的 monocytic 房间上探索了在 CD14 和 CXCR4 之间的潜在的关系结合 FITC 的 anti-CD14 有约束力单音的同种细胞的抗体(TUK4 和 UCHM1 ) 到 U937,当另一 CX-CR4-specific mAb B-R24 没在这绑定上显示出任何效果时。在另一方面,二 anti-CD14 单音的同种细胞的抗体(TK4 和 UCH-M1 ) 显然禁止了结合 PE 的 anti-CXCR4 mAb 12G5 的绑定到 U937 但是没禁止 mAb 12G5 的绑定到 CXCR4-transfected 3T3 房间(3T3。T4, CXCR4 ) ,它显示由 CD14 特定的 mAbs 堵住对 CXCR4 有约束力的 mAb 12G5 不涉及可能性那 CD14 特定的 mAbs 直接绑在 CXCR4。这些结果在 monocytic 房间线 U937 上建议了在 CD14 和 CXCR4 之间的一个靠近的协会的存在。 | Yang Hengwen Lan Canhui Chen Yinghua | 2007 | Progress in Natural Science:Materials International2007，17，8： | 0 |
| 12 | Effects of iron oxide nanoparticles on phenotype and metabolite changes in hemp clones(Cannabis sativa L.)显示文摘We investigated the effect of iron oxide nanoparticles(Fe_(3)O_(4)NPs,~17 nm in size)on the phenotype and metabolite changes in hemp(Cannabis sativa L.),an annual crop distributed worldwide.Hemp clones were grown in hydroponic cultures with Fe_(3)O_(4)NPs(50,100,200,or 500 mg/L)for four weeks.TEM and ICP-MS were used to determine Fe_(3)O_(4)NPs uptake and translocation.LC-MS-based metabolomics was employed to explore the deep insight into the effect of Fe_(3)O_(4)NPs on hemp plants.The results revealed that plant growth enhanced gradually with increasing concentrations of given NPs up to 200 mg/L,which improved the fresh weight and dry weight by 36.13%and 74.68%,respectively,compared to the control.Even at a high dose(500 mg/L),Fe_(3)O_(4)NPs promoted plant growth,including increased biomass and tissue length.NPs significantly increased the iron and chlorophyll content in plant tissues Increased catalase activity and reduced hydrogen peroxide content in hemp leaves suggested that the Fe_(3)O_(4)NPs activated the defense system.TEM showed that NPs were abundantly attached to the cell wall and dispersed throughout the root cells.Metabolomics revealed that Fe_(3)O_(4)NPs induced metabolic reprogramming in hemp leaves,including the up-regulation of carbohydrates and organic acids,and down-regulation of antioxidants,especially tetrahydrocannabinol(THC).The significantly up-regulated metabolites,including peonidin and 2-hydroxycinnamic acid,could be involved in photosynthesis in hemp plants.These results demonstrate the potential of Fe_(3)O_(4)NPs for promoting hemp growth and decreasing the THC content at low doses. | Canhui Deng Qing Tang Zemao Yang Zhigang Dai Chaohua Cheng Ying Xu Xiaojun Chen Xiaoyu Zhang Jianguang Su | 2022 | Frontiers of Environmental Science & Engineering2022，16，10： | 0 |
| 13 | Topological prime显示文摘This paper describes a general method, called topological prime, to stitch functional groups to a substrate of entropic polymer network. The precursor of a topological primer contains polymers, crosslinkers, and coupling agents. When the precursor is applied on the surface of the substrate, the crosslinkers link the primer polymers into a primer network, in topological entanglement with the substrate network, while the coupling agents link the primer network to the functional groups. The use of topological prime is demonstrated by priming a hydrophobic elastomer of an arbitrary shape for hydrophilic coating. We describe an approach that fulfills two fundamental requirements: wetting and adhesion. The coated elastomer maintains hydrophilicity and lubricity after stretch, scratch, swell, and slide. As a further demonstration, a hydrogel substrate is primed for hydrophobic coating. Topological prime opens an enormous space for applications in engineering and biomedicine. | YANG XuXu YANG CanHui LIU JunJie YAO Xi SUO ZhiGang | 2020 | Science China(Technological Sciences)2020，63，7： | 0 |
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