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| 1 | Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment显示文摘Salmonella:mediated cancer therapy has achieved remarkable anti-tumor effects in experimental animal models,but the detailed mechanism remains unsolved.In this report,the active involvement of the host immune response in this process was confirmed by comparing the tumor-suppressive effects of Salmonella in immunocompetent and immunodeficient mice bearing melanoma allografts.Since flagella are key inducers of the host immune response during bacterial infection,flagella were genetically disrupted to analyse their involvement in Salmonella-mediated cancer therapy.The results showed that flagellum-deficient strains failed to induce significant anti-tumor effects,even when more bacteria were administered to offset the difference in invasion efficiency.Flagella mainly activate immune cells via Flagellin/Toll-like receptor 5(TLR5)signalling pathway.Indeed,we showed that exogenous activation of TLR5 signalling by recombinant Flagellin and exogenous expression of TLR5 both enhanced the therapeutic efficacy of flagellum-deficient Salmonella against melanoma.Our study highlighted the therapeutic value of the interaction between Salmonella and the host immune response through Flagellin/TLR5 signalling pathway during Salmonella-mediated cancer therapy,thereby suggesting the potential application of TLR5 agonists in the cancer immune therapy. | Jianxiang Chen Yiting Qiao Guo Chen Cunjie Chang Heng Dong Bo Tang Xiawei Cheng Xiufeng Liu Zichun Hua | 2021 | Acta Pharmaceutica Sinica B2021，11，10： | 6 |
| 2 | Comparative analysis of significant wave height between a new Southern Ocean buoy and satellite altimeter显示文摘中国于2019年第35次南极考察中,首次在南大洋布放了锚系实时综合观测浮标(西风带海洋环境监测浮标,WEMB),为深入了解此海区的海洋环境变化提供了宝贵资料.国家海洋技术中心WEMB研究团队基于AVISO公开发布的多颗卫星高度计L3产品,通过数据配对,误差统计和最小二乘线性拟合等方法,对西风带海洋环境监测浮标的有效波高数据误差进行了分析与校正.校正后的浮标有效波高统计显示西风带常年处于大浪以上海况,观测期间内57%处于巨浪海况,并且伴随有高度相关的大风天气. | Jianjun Kang Runyu Mao Yiting Chang Hongli Fu | 2021 | Atmospheric and Oceanic Science Letters2021，14，5： | 3 |
| 3 | Recent progress in perovskite solar cells:material science显示文摘Perovskite solar cells represent a promising third-generation photovoltaic technology with low fabrication cost and high power conversion efficiency.In light of the rapid development of perovskite materials and devices,a systematic survey on the latest advancements covering a broad range of related work is urgently needed.This review summarizes the recent major advances in the research of perovskite solar cells from a material science perspective.The discussed topics include the devices based on different type of perovskites(organic-inorganic hybrid,all-inorganic,and lead-free perovskite and perovskite quantum dots),the properties of perovskite defects,different type of charge transport materials(organic,polymeric,and inorganic hole transport materials and inorganic and organic electron transport materials),counter electrodes,and interfacial materials used to improve the efficiency and stability of devices.Most discussions focus on the key progresses reported within the recent five years.Meanwhile,the major issues limiting the production of perovskite solar cells and the prospects for the future development of related materials are discussed. | Jiang-Yang Shao Dongmei Li Jiangjian Shi Chuang Ma Yousheng Wang Xiaomin Liu Xianyuan Jiang Mengmeng Hao Luozheng Zhang Chang Liu Yiting Jiang Zhenhan Wang Yu-Wu Zhong Shengzhong(Frank)Liu Yaohua Mai Yongsheng Liu Yixin Zhao Zhijun Ning Lianzhou Wang Baomin Xu Lei Meng Zuqiang Bian Ziyi Ge Xiaowei Zhan Jingbi You Yongfang Li Qingbo Meng | 2023 | Science China Chemistry2023，66，1： | 3 |
| 4 | Constructions of Optical FIFO Queues显示文摘 | Chang Chengshang Chen Yiting Lee Duan-Shin | 2006 | IEEE Transactions on Information Theory2006，52，6： | 1 |
| 5 | Factor analysis of the functional properties of rice flours from mutant genotypes 显示文摘 | Lin J H Singh H Chang Yiting | 2011 | Food Chemistry2011，126，3： | 1 |
| 6 | Reuse and valorization of vanadium and tungsten from waste V~Oc--WOJ Ti02 SCR catalyst 显示文摘 | Huo Yiting Chang Zhidong Li Wenjun | 2015 | Waste Biomass Valor2015，，6： | 1 |
| 7 | Analytical design of two-mode dual-band filters using E-shaped resonators显示文摘 | Kuo Yiting Chang Chiyang | | 0，，02： | 1 |
| 8 | 4350<ce:hsp sp='0.25'/>W quasi-continuous-wave operation of a diode face-pumped ceramic Nd: YAG slab laser显示文摘 | Junchi Chen Jiang Li Jialin Xu Wenbin Liu Yong Bo Xiqi Feng Yiting Xu Dongliang Jiang Zhongzheng Chen Yubai Pan Yading Guo Biao Yan Chang Guo Lei Yuan Hongtao Yuan Yanyong Lin Yunsheng Xiao Qinjun Peng Wenqiang Lei Dafu Cui Zuyan Xu | 2014 | Optics and Laser Technology2014，，： | 1 |
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