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| 1 | Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients显示文摘Pathogenic human coronavirus infections,such as severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERS-CoV),cause high morbidity and mortality[1,2].Recently,a severe pneumonia-associated respiratory syndrome caused by a new coronavirus(SARS-CoV-2)was reported in December 2019 in the city of Wuhan,Hubei province,China[3-5],which was also named as pneumonia-associated respiratory syndrome(PARS)[6]and can cause coronavirus disease 2019(COVID-19)to seriously endanger human health. | Yonggang Zhou Binqing Fu Xiaohu Zheng Dongsheng Wang Changcheng Zhao Yingjie Qi Rui Sun Zhigang Tian Xiaoling Xu Haiming Wei | 2020 | National Science Review2020，7，6： | 54 |
| 2 | First Imported Case of SARS-CoV-2 Omicron Subvariant BA.5—Shanghai Municipality,China,May 13,2022显示文摘On April 27,2022,an international flight KL857 from Amsterdam,the Netherlands arrived at Pudong International Airport,Shanghai Municipality.Passengers were transferred to the quarantine hotel for a routine 14-day medical observation in Songjiang District and regularly tested for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).One of the passengers(a 37-year-old Chinese male)was reported positive and diagnosed as a mild case on April 29.The case set out from Uganda(flight KL535)on April 25 and transferred at Amsterdam,the Netherlands on April 26 and Seoul,the Republic of Korea(KL857)on April 27.The patient has been vaccinated in four doses against coronavirus disease 2019(COVID-19)(Beijing Institute of Biological Products Co.,Ltd)in China and Uganda.After diagnosis,he was transferred to Shanghai Public Health Clinical Center for treatment.He recovered after treatment and was discharged on May 12. | Hui Jiang Changcheng Wu Wenbo Xu Hongyou Chen Fanghao Fang Min Chen Chaonan Wang Lingyue Yuan Huanyu Wu Zheng Teng Jinyuan Guo Yaxu Zheng Xihong Lyu Xuefei Qiao Guizhen Wu Wenjie Tan Xi Zhang | 2022 | China CDC weekly2022，4，30： | 10 |
| 3 | Risk factors of CMV infection in patients after umbilical cord blood transplantation: a multicenter study in China显示文摘Objective:This retrospective study examined risk factors for cytomegalovirus(CMV)infection after umbilical cord blood transplantation(UCBT)and the impact of CMV infection on patient survival.Methods:In all 176 patients,plasma CMV DNA was negative prior to the transplantation,and examined twice a week for 100 d,and then once weekly for additional 300 d.Preemptive antiviral therapy(ganciclovir or foscarnet)was started in patients with>1,000/mL copies of CMV DNA but no full-blown CMV disease,and was discontinued upon two consecutive negative reports of blood CMV DNA test.The survival and risk factors for CMV infection or disease were examined using logistic regression.Results:CMV infection developed in 71%(125/176)of the patients,with a median onset of 32 d.Four patients(2.3%)developed CMV disease.Neither the 5-year overall survival(OS)nor event-free survival(EFS)differed significantly in infected patients vs.those with no infection(59.4%vs.64.8%,P=0.194;53.4%vs.59.1%,P=0.226).A stepwise multivariate analysis indicated an association of CMV infection with age,high-dose glucocorticoids,the number of transplanted CD34+cells,and the number of platelet transfusion,but not with gender,the conditioning regimen,and the day of neutrophil recovery and chronic graft-versushost disease(cGVHD).Conclusions:CMV infection is very common after UCBT,but does not seem to affect long-term survival with preemptive antiviral treatment. | Juan Tong Zimin Sun Huilan Liu Liangquan Geng Changcheng Zheng Baolin Tang Kaidi Song Wen Yao Xin Liu | 2013 | Chinese Journal of Cancer Research2013，25，6： | 8 |
| 4 | Surface defect ordered Cu_(2)ZnSn(S,Se)_(4) solar cells with efficiency over 12% via manipulating local substitution显示文摘The environmentally friendly Cu_(2)ZnSn(S,Se)_(4)(CZTSSe) compounds are promising direct bandgap materials for application in thin film solar cells, but the spontaneous surface defects disordering would lead to large open-circuit voltage deficit(V_(oc,deficit)) and significantly limit kesterite photovoltaics performance,primarily arising from the generated more recombination centers and insufficient p to n conversion at p-n junction. Herein, we establish a surface defects ordering structure in CZTSSe system via local substitution of Cu by Ag to suppress disordered Cu_(Zn) defects and generate benign n-type Zn_(Ag) donors. Taking advantage of the decreased annealing temperature of Ag F post deposition treatment(PDT), the high concentration of Ag incorporated into surface absorber facilitates the formation of surface ordered defect environment similar to that of efficient CIGS PV. The manipulation of highly doped surface structure could effectively reduce recombination centers, increase depletion region width and enlarge the band bending near p-n junction. As a result, the Ag F-PDT device finally achieves maximum efficiency of 12.34% with enhanced V_(oc) of 0.496 V. These results offer a new solution route in surface defects and energy-level engineering, and open the way to build up high quality p-n junction for future development of kesterite technology. | Changcheng Cui Dongxing Kou Wenhui Zhou Zhengji Zhou Shengjie Yuan Yafang Qi Zhi Zheng Sixin Wu | 2022 | Journal of Energy Chemistry2022，31，4： | 4 |
| 5 | The role of intraoperative electron radiotherapy in centrally located hepatocellular carcinomas treated with narrow-margin (<1 cm) hepatectomy: a prospective, phase 2 study显示文摘Background: Postoperative radiotherapy (RT) is known to play an important role in the treatment of hepatocellular carcinomas (HCCs), but the specific role of intraoperative electron radiotherapy (IOERT) in HCCs remains unclear. The aim of this study was to investigate the safety and efficacy of IOERT in centrally located HCCs treated with narrow-margin (<1 cm) hepatectomy. Methods: This was a single-center, phase 2, prospective non-randomized controlled study, including 268 patients with centrally located HCCs who underwent narrow-margin hepatectomy. The patients were subsequently allocated to the IOERT group (n=59) or to the control group (n=65). The primary outcome of the study was to compare recurrence-free survival (RFS) between the IOERT group and the control group, and the secondary outcome was to compare overall survival (OS) rate between the two groups. Results: Of 268 patients enrolled, a total of 124 were included in the study: 59 in IOERT group, 65 in control group. The 1-, 2-, 3-year RFS rates were 79.3%, 62.1% and 45.8% for patients in the IOERT group, and 47.6%, 28.6%, and 22.9% for patients in the control group, respectively (P=0.025). The 1-, 2-, and 3-year OS rates were 100.0%, 94.9%, and 83.7% for patients in the IOERT group, and 92.3%, 87.5%, and 79.4% for patients in the control group, respectively (P=0.314). Subgroup analysis of MVI (+) patients revealed that RFS and OS are significantly prolonged in the IOERT subgroup as compared to the control, whereas there was no significant difference of RFS and OS between the two groups in MVI (−) patients. Conclusions: IOERT for centrally located HCCs with concurrent narrow-margin hepatectomy was feasible and safe. Statistically better RFS rate was observed in the IOERT group compared to the control group. Subgroup analysis revealed that IOERT was more beneficial for postoperative survival of HCC patients with MVI. Trial Registration: ChiCTR-TRC-12002802;www.who.int/ictrp. | Liming Wang Yunhe Liu Weiqi Rong Fan Wu Weibo Yu Kan Liu Shengtao Lin Yiling Zheng Kai Zhang Tana Siqin Changcheng Tao Mei Liu Bo Chen Qinfu Feng Jianxiong Wu | 2022 | Hepatobiliary Surgery and Nutrition2022，11，4： | 2 |
| 6 | Extinction of the zero-phonon line and the first-order phonon sideband in excitonic luminescence of ZnO at room temperature: the self-absorption effect显示文摘It is firmly demonstrated in experiment that the self-absorption(SA) effect can lead to the extinction of the zero-phonon line and the first-order longitudinal optical phonon sideband of free excitonic luminescence of ZnO at room temperature. Moreover, effectiveness degree of SA effect is found to be dependent on both absorption coefficient and travelling distance of emitted photons, as well as even lattice temperature, which is uniquely reflected by the redshift amount in emission peak in ZnO. It is also unambiguously proved that the SA effect still strictly obeys the Beer-Lambert law of absorption. This work not only uncovers the long-term puzzle of significant redshift of emission peak of ZnO at higher temperatures, but also shows that the SA effect may have to be carefully taken into consideration in the study of spontaneous emission, laser and relevant optoelectronic processes in luminescent materials and optoelectronic devices. | Honggang Ye Zhicheng Su Fei Tang Changcheng Zheng Guangde Chen Jian Wang Shijie Xu | 2017 | Science Bulletin2017，62，22： | 2 |
| 7 | Effect of drought on pigments, osmotic adjustment and antioxidant enzymes in six woody plant species in karst habitats of southwestern China显示文摘 | Changcheng Liu Yuguo Liu Ke Guo Dayong Fan Guoqing Li Yuanrun Zheng Lifei Yu Rui Yang | 2010 | Environmental and Experimental Botany2010，，2： | 2 |
| 8 | Realization of high-performance tri-layer graphene saturable absorber mirror fabricated via a one-step transfer process显示文摘Graphene,as a saturable absorber(SA),has attracted much attention for its application in ultrashort pulse fiber lasers due to its ultrafast interband carrier relaxation and ultra-broadband wavelength operation.Nevertheless,during the stacking process of monolayer graphene layer,the induced nonuniform contact at the interface of graphene layers deteriorate the device performance.Herein,we report the fabrication of graphene saturable absorber mirrors(SAMs)via a one-step transfer process and the realization of the much enlarged modulation depth and the much reduced nonsaturable loss with tri-layer graphene(TLG)than single-layer graphene(SLG)due to the improved uniform contact at the interface.Moreover,the operation of 1550 nm mode-locked Er-doped fiber laser with the TLG SAM exhibits excellent output characteristics of the maximum output power of 9.9 mW,a slope efficiency of 2.4%and a pulse width of 714 fs.Our findings are expected to pave the way toward high-performance ultrashort pulse fiber lasers based on graphene SAs. | Cheng Jiang Xu Wang Jian Liu Jiqiang Ning Changcheng Zheng Xiaohui Li Ziyang Zhang | 2020 | Journal of Semiconductors2020，41，1： | 2 |
| 9 | Quantum cascade superluminescent light emitters with high power and compact structure显示文摘Quantum cascade(QC)superluminescent light emitters(SLEs)have emerged as desirable broadband mid-infrared(MIR)light sources for growing number of applications in areas like medical imaging,gas sensing and national defense.However,it is challenging to obtain a practical high-power device due to the very low efficiency of spontaneous emission in the intersubband transitions in QC structures.Herein a design of^5μm SLEs is demonstrated with a two-phonon resonancebased QC active structure coupled with a compact combinatorial waveguide structure which comprises a short straight part adjacent to a tilted stripe and to a J-shaped waveguide.The as-fabricated SLEs achieve a high output power of 1.8 mW,exhibiting the potential to be integrated into array devices without taking up too much chip space.These results may facilitate the realization of SLE arrays to attain larger output power and pave the pathway towards the practical applications of broadband MIR light sources. | Jialin Sun Chuncai Hou Hongmei Chen Jinchuan Zhang Ning Zhuo Jiqiang Ning Changcheng Zheng Zhanguo Wang Fengqi Liu Ziyang Zhang | 2020 | Journal of Semiconductors2020，41，1： | 1 |
| 10 | Study on the availability opening size of throttle and af- fection to the velocity characteristic of shock absorber 显示文摘 | Zhou Changcheng Zheng Zhiyun Gu Liang | 2007 | Beiiing Institute of Technology2007，16，1： | 1 |
| 11 | Influence of Dechlorination Temperature on Propane Dehydrogenation over Pt-θ-Al2O3显示文摘Several Pt-θ-Al_2O_3 catalysts with similar ultra-low Cl contents were used to investigate the influence of dechlorination temperature on propane dehydrogenation reaction. The Pt-θ-Al_2O_3 catalyst treated at a highest dechlorination temperature showed a lowest propane rate and propylene selectivity. The scanning transmission electron microscopy showed that the dispersions of Pt nanoparticles decreased with an increasing dechlorination temperature. The temperature-programmed reduction analysis showed that higher dechlorination temperature could lead to strong interactions between the metal and support, making it difficult to reduce Pt nanoparticles. The temperature-programmed oxidation analysis implied that more coke was deposited on the metal for catalyst treated at higher dechlorination temperature. The Raman spectra and the H/C ratio showed that more side-reactions, such as cracking and severe deep dehydrogenation reactions, occurred on catalysts treated at higher dechlorination temperatures. Therefore, the lower the dispersion of Pt nanoparticles was, the stronger the metal-support interactions and increased side-reactions would be, resulting in lower catalytic activity for Pt-θ-Al_2O_3 treated with higher dechlorination temperature. | Liu Jie Liu Changcheng Ma Aizeng Da Zhijian Zheng Huidong | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，4： | 1 |
| 12 | Study on the availability opening size of throttle and affection to the velocity characteristic of shock absorbe显示文摘 | Zhou Changcheng Zheng Zhiyun Gu Liang | 2007 | Beijing Institute of Technology2007，16，1： | 1 |
| 13 | hnplementation of LDPC encoding to DTMB standard based on FPGA 显示文摘 | Xiang Ouyang Changcheng Ruan Lingxiang Zheng | 2011 | IEEE Computer and Information Science2011，，： | 1 |
| 14 | Design Method for Throttle Holes Area of Tele- scopic Shock Absorber for Small Electric Vehicles 显示文摘 | Zhou Changcheng Zheng Zhiyun Zhang Xueyi | 2009 | Journal of Asian Electric Vehicles2009，7，1： | 1 |
| 15 | Design Method for Throttle Holes Area of Telescopic Shock Absorber for Small Electric Vehicles 显示文摘 | Zhou Changcheng Zheng Zhiyun Zhang Xueyi | 2009 | Journal of Asian Electric Vehicles2009，7，1： | 1 |
| 16 | Growth plasticity of conifers did not avoid declining resilience to soil and atmospheric droughts during the 20th century显示文摘Background:Plasticity in response to environmental drivers can help trees cope with droughts.However,our understanding of the importance of plasticity and physiological adjustments in trees under global change is limited.Methods:We used the International Tree-Ring Data Bank(ITRDB)to examine 20th century growth responses in conifer trees during(resistance)and following(resilience)years of severe soil and atmospheric droughts occurring in isolation or as compound events.Growth resilience indices were calculated using observed growth divided by expected growth to avoid spurious correlations,in which the expected values were obtained by the autoregressive moving average(ARIMA)model.We used high atmospheric vapour pressure deficit(VPD)to select years of atmospheric drought and low annual values of the Standardized Precipitation-Evapotranspiration Index(SPEI)to select years with soil drought.We acquired the sensitivities(i.e.,the slopes of the relationships)by fitting the resilience indices as a function of environmental drivers,and assessed how these sensitivities changed over time for different types of drought events using linear mixed models.We also checked whether plasticity in growth responses was sufficient to prevent long-term trends of growth reductions during or after severe droughts.We acknowledge that by focusing on the response of surviving trees from the ITRDB we are potentially biasing our results towards higher resilience,as stand level responses(e.g.,mortality)may result in lowered competition after the disturbance event.Results:Sensitivities of resilience to VPD and SPEI changed throughout the 20th century,with the directions of these changes often reversing in the second half of the century.For the 1961–2010 period,changing sensitivities had positive effects on resilience,especially following years of high-VPD and compound events,avoiding growth losses that would have occurred if sensitivities had remained constant.Despite sensitivity changes,resilience was still lower at the end of the 20th century compared to the beginning of the century.Conclusions:Future adjustments to low-SPEI and high-VPD events are likely to continue to compensate for the trends in climate only partially,leading to further generalized reductions in tree growth of conifers.An improved understanding of these plastic adjustments and their limits,as well as potential compensatory processes at the stand level,is needed to project forest responses to climate change. | Tong Zheng Jordi Martínez-Vilalta Raúl García-Valdés Antonio Gazol J.Julio Camarero Changcheng Mu Maurizio Mencuccini | 2023 | Forest Ecosystems2023，10，2： | 0 |
| 17 | Phosphorous-Modified Carbon Nanotube-Supported Pt Nanoparticles for Propane Dehydrogenation Reaction显示文摘The sintering of Pt nanoparticles is one of the main reasons for catalyst deactivation during the high-temperature propane dehydrogenation(PDH) reaction. Promoters and supports have been introduced to prolong the catalyst life.However, it is still necessary to develop novel catalysts with robust stability. Herein, the phosphorus-modified carbon nanotube-supported Pt nanoparticles were employed for the PDH process. Phosphorus modification improves the Pt dispersion, effectively promoting the activity of Pt/P-CNTs. Additionally, the phosphorus-modified CNTs can interact strongly with Pt nanoparticles by improving the electron transfer or hybridization, stabilizing Pt nanoparticles from agglomeration, and significantly enhancing the catalyst stability. | Liu Jie Liu Changcheng Da Zhijian Zheng Huidong | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，1： | 0 |
| 18 | Short-term effects of fire disturbance on CH4 emission from forested wetlands in the Xiaoxing’an Mountains, Northeast China显示文摘Using static chamber gas chromatography, we determined the seasonal dynamics, controlling factors, and distribution patterns of forest swamp CH4 levels and related environmental factors (temperature, water level) after fire disturbance in the Xiaoxing’an Mountains. The results showed the following: during the growing season, the annual CH4 emission distribution ranged from - 0.001 ± 0.012 to 22.373 ± 3.650 mg m^-2 h^-1;mild fire caused the swamp CH4 emission flux of tussock, shrub, Alnus sibirica and birch swamp to increase by 56.0–524.7%;at low water levels, temperature had a significant influence on the swamp type, and the correlation between the methane emission flux and temperature was significantly strengthened;after a fire disturbance, methane emissions from all types of marsh were highest in summer and second highest in autumn, with a weak absorption in spring;and along the water environment gradient of the transition zone, the CH4 emission flux presented a decreasing trend in its spatial distribution pattern. | Han Gu Wenyu Zheng Dawei Xu Changcheng Mu | 2019 | Journal of Forestry Research2019，30，3： | 0 |
| 19 | STUDY ON THE SEPARATION OF PENTOSE AND HEXOSE FROM GLUCOSE YEAST WATER显示文摘D-ribose is a unique, 5-carbon sugar that occurs naturally in all living cells. D-ribose has been used as a staring material for preparation of some certain medicines or just as a new nutraceutical that helps the body naturally restore its energy level. The fermentative processes are the best for their relatively simple series of production steps and relatively cheap starting materials. However, because of the many impurities in glucose yeast water and its dark color, pretreatment and purification must be done to the fluid before D-ribose can be separated. In this paper, separation and purification of D-ribose was carried out using cation exchange resins, of which Ca2+ exchange resin had the best effect. The optimal condition for adsorption is a flow velocity of 0.5BV/h at adsorption temperature of 25℃. The optimal condition for desorption is a flow velocity of 0.5 BV/h at desorption temperature of 80℃. | ZHENG Changcheng ZHANG Jinfeng LU Yan DENG Guocai CHEN Rongti | 2000 | Chinese Journal of Reactive Polymers2000，9，2： | 0 |
| 20 | A descriptor of “material genes”: Effective atomic size in structural unit of ionic crystals显示文摘The atomic size of each element, described by the ionic radius, is one category of 'material genes' and can facilitate our understanding of atomic arrangements in compounds. Most of the ionic radii currently used to measure the sizes of cations and anions in ionic crystals are derived from hard-sphere model based on the coordination numbers, or the soft-sphere model incorporating the effect of ionic polarization. Herein we take a first step towards a novel 'effective atomic size'(EAS) model,which takes into consideration the impact of the types and number of neighboring atoms on the relationship between ionic radii and interatomic distances. Taking the binary compounds between Group IA/IIA and VIA/VIIA elements gathered from the latest databases as an example, we show that the proposed EAS model can yield excellent agreement between the predicted and the DFT-calculated interatomic distances, with deviation of less than 0.1 ?. A set of EAS radii for ionic crystals has been compiled and the role of coordination numbers, geometric symmetry and distortion of structural units has been examined. Thanks to its superior predictability, the EAS model can serve as a foundation to analyze the structure of newly-discovered compounds and to accelerate materials screening processes in the future works. | CHEN Dong LI ShunNing JIE JianShu LI SiBai ZHENG ShiSheng WENG MouYi YU ChangCheng LI ShuCheng CHEN DaJun PAN Feng | 2019 | Science China(Technological Sciences)2019，62，5： | 0 |
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