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1Analyzing the Flavor Compounds in Chinese Traditional Fermented Shrimp Pastes by HS-SPME-GC/MS and Electronic Nose显示文摘Shrimp paste is a type of condiments with high nutritional value.However,the flavors of shrimp paste,particularly the non-uniformity flavors,have limited its application in food processing.In order to identify the characteristic flavor compounds in Chinese traditional shrimp pastes,five kinds of typical commercial products were evaluated in this study.The differences in the volatile composition of the five products were investigated.Solid phase micro-extraction method was employed to extract the volatile compounds.GC-MS and electronic nose were applied to identify the compounds,and the data were analyzed using principal component analysis(PCA).A total of 62 volatile compounds were identified,including 8 alcohols,7 aldehydes,3 ketones,7 ethers,7 acids,3 esters,6 hydrocarbons,12 pyrazines,2 phenols,and 7 other compounds.The typical volatile compounds contributing to the flavor of shrimp paste were found as follows:dimethyl disulfide,dimethyl tetrasulfide,dimethyl trisulfide,2,3,5-trimethyl-6-ethyl pyrazine,ethyl-2,5-dimethyl-pyrazine,phenol and indole.Propanoic acid,butanoic acid,furans,and 2-hydroxy-3-pentanone caused unpleasant odors,such as pungent and rancid odors.Principal component analysis showed that the content of volatile compounds varied depending on the processing conditions and shrimp species.These results indicated that the combinations of multiple analysis and identification methods could make up the limitations of a single method,enhance the accuracy of identification,and provide useful information for sensory research and product development.FAN Yan YIN Li-ang XUE Yong LI Zhaojie HOU Hu XUE Changhu 2017Journal of Ocean University of China2017,16,2:25
2Recent Advances in Researches on Physiologically Active Substances in Holothurians显示文摘In this report, we reviewed recent literature on physiologically active substances from sea cucumbers (SCs) andtheir activities together with results obtained from our study. Preventive properties against lipid metabolism were reported inrats using a whole SC preparation with no particular constituent specified. Administration of the preparation lowered serumand hepatic cholesterol levels and improved the HDL/LDL ratio. These functions may be attributed to the stimulatory effectof the extract on the secretion of cholesterol in feces. Novel fucosylated chondroitin sulfates (FCSs) from Ludwigothureagrisea significantly induced fibroblast growth factor 2-dependent angiogenesis in human umbilical vein endothelial cells (HU-VECs). The proangiogenetic activity seemed attributable to the action of the sulfated fucose branches on the polysaccharide.SCs contain mycosporine-like amino acids (MAAs) that are capable of absorbing UV. A biogenetic precursor of MAAs wasfirst reported in SCs. The anti-proliferative effects of a branched chain fatty acid from a sea cucumber on prostate cancercells was reported with the activity of 5-lipoxygenase. Glycosphingolipid constituents in SCs have been systematically ana-lyzed over the past ten years. The results showed that the gangliosides in several SCs differed from those of mammals in thata sialic acid of SC gangliosides directly binded to glucose of cerebroside. Neuritogenic activity of the glycosphingolipids wasdemonstrated in vitro experiments and may lead to the development of therapeutic products for neurological disorders. Ourstudy also showed that sphingoid bases, the hydrolyzed products of glycosphingolipids from SCs, induced significant apoptosisin several tumor cell lines.Hirata Takashi Zaima Nobuhiro Yamashita Kyoko Noguchi Ryoko XUE Changhu Sugawara Tatsuya 2005Journal of Ocean University of China2005,4,3:14
3Changes in the Contents of ATP and Its Related Breakdown Compounds in Various Tissues of Oyster During Frozen Storage显示文摘The changes in the contents of adenosine 5’-triphosphate (ATP) and its related breakdown compounds were investigated in the adductor muscle, mantle, gill and body trunk of oyster (Crassostrea gigas) during frozen storage at -20℃ and -30℃ and compared with that of the fresh oyster. The investigation was performed using an HPLC system. Different extents of ATP decomposi- tion were found in various tissues frozen at the two temperatures. The K, K’ and A.E.C values were calculated as the chemical fresh- ness indices. Considering the results of sensory evaluation, the A.E.C. value in body trunk at -20℃ and -30℃ could be used as the best freshness index for frozen oyster.WANG Qi XUE Changhu LI Zhaojie FU Xueyan XU Jie XUE Yong 2007Journal of Ocean University of China2007,6,4:13
4Antioxidation Activities of Low-Molecular-Weight Gelatin Hydrolysate Isolated from the Sea Cucumber Stichopus japonicus显示文摘Gelatin extracted from the body wall of the sea cucumber (Stichopus japonicus) was hydrolyzed with flavourzyme.Low-molecular-weight gelatin hydrolysate (LMW-GH) of 700-1700 Da was produced using an ultrafiltration membrane bioreactor system.Chemiluminescence analysis revealed that LMW-GH scavenges high free radicals in a concentration-dependent manner;IC50 value for superoxide and hydroxyl radicals was 442 and 285 μg mL-1,respectively.LMW-GH exhibited excellent inhibitory characteristics against melanin synthesis and tyrosinase activity in B16 cells.Furthermore,LMW-GH notably increased intracellular glutathione (GSH),which in turn suppressed melanogenesis.LMW-GH performs antioxidation activity,holding the potential of being used as a valuable ingredient in function foods,cosmetics and pharmaceuticals or nutriceuticals.WANG Jingfeng WANG Yuming TANG Qingjuan WANG Yi CHANG Yaoguang ZHAO Qin XUE Changhu 2010Journal of Ocean University of China2010,9,1:13
5CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer显示文摘Objective: We studied the application of CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer (NSCLC). Methods: Eleven patients with NSCLC, who were treated with three-dimensional con-formal radiation therapy, were studied. Each patient underwent twice sequential planning CT scan, i.e., at pre-treatment, and at mid-treatment for field reduction planning. Three treatment plans were established in each patient: treatment plan A was based on the pre-treatment planning CT scans for the first course of treatment, plan B on the mid-treatment planning CT scans for the second course of treatment, and treatment plan F on the fused images for the whole treatment. The irradiation doses received by organs at risk in the whole treatment with treatment A and B plans were estimated by the plus of the parameters in treatment plan A and B, assuming that the parameters involve the different tissues (i.e. V20=AV20+BV20), or the same tissues within an organ (i.e. Dmax=ADmax+BDmax). The assessment parameters in the treatment plan F were calculated on the basis of the DVH of the whole treatment. Then the above assessment results were compared. Results: There were marked differ-ences between the assessment results derived from the plus of assessment parameters in treatment plan A and B, and the ones derived from treatment plan F. Conclusion: When a treatment plan is altered during the course of radiation treatment, image fusion technique should be performed in the establishment of a new one. The estimation of the assessment parameters for the whole treatment with treatment plan A and B by simple plus, is inaccurate.WeiGe Guangjin Yuan Changhu Li Yaogui Wu Yanyan Zhang Ximing Xu 2008The Chinese-German Journal of Clinical Oncology2008,7,6:10
6Rheological and Structural Properties of Sea Cucumber Stichopus japonicus During Heat Treatment显示文摘Changes in tissue structure, rheological properties and water content of raw and heated sea cucumber meat werestudied. Sea cucumber Stichopus japonicus was heated at 25°C, 70°C and 100 °C water for 5 min. The structural changeswere observed using a light microscope and the rheological parameters (rupture strength, adhesive strength and deformation)determined using a texture meter. Microscopic photograph revealed that the structural change of heated meat was greaterthan that of raw meat. The rupture strength, adhesive strength and deformation of raw meat were smaller than those of theheated meat. Meanwhile, rheological parameters showed positive correlation with heating temperature. These changes aremainly caused by thermal denaturation and gelatinization of collagen during heating. These changes were also evidenced inobservations using a light microscope and differential scanning calorimetry.GAO Xin XUE Dongmei ZHANG Zhaohui XU Jiachao XUE Changhu 2005Journal of Ocean University of China2005,4,3:10
7Reduction of Cd in Rice through Expression of OXS3-like Gene Fragments显示文摘Wang, Changhu Guo, Weili Ye, Shan Wei, Pengcheng Ow, David W. 2016Molecular Plant2016,9,2:5
8Extraction of Astaxanthin from Euphausia pacific Using Subcritical 1,1,1,2-tetrafluoroethane显示文摘Euphausia pacific is an important source of natural astaxanthin.Studies were carried out to assess the extractability of astaxanthin from E.pacific using subcritical 1,1,1,2-tetrafluoroethane(R134a).To examine the effects of multiple process variables on the extraction yield,astaxanthin was extracted under various conditions of pressure(30-150 bar),temperature(303-343 K),time(10-50 min),flow rate(2-10 g min-1),moisture content(5.5%-63.61%),and particle size(0.25-0.109 mm).The results showed that the extraction yield increased with temperature,pressure,time and flow rate,but decreased with moisture content and particle size.A maximum yield of 87.74% was obtained under conditions of 100 bar,333 K,and 30 min with a flow rate of 6 g min-1 and a moisture content of 5.5%.The substantial astaxanthin yield obtained under low-pressure conditions demonstrates that subcritical R134a is a good alternative to CO 2 for extraction of astaxanthin from E.pacific.HAN Yuqian MA Qinchuan WANG Lan XUE Changhu 2012Journal of Ocean University of China2012,11,4:5
9A New Species of the Genus Thermophis(Serpentes: Colubridae) from Shangri-La, Northern Yunnan, China, with a Proposal for an Eclectic Rule for Species Delimitation显示文摘The hot-spring snakes, Thermophis, were previously known only from the Tibet Autonomous Region and Western Sichuan, China. During the past two years, three adult hot-spring snakes(2 females, 1 male) were sampled in Shangri-La, northern Yunnan, China, thus expanding their known distribution region towards the southeast. This site is the southeastern-most corner of the Tibetan Plateau and the southernmost tip of the Hengduan Mountains(Mts.). Phylogenetic analysis of mitochondrial(mt) and nuclear(n) DNA segments suggested that the three specimens belong to the genus of Thermophis. Morphologically, the new species is more similar to T. zhaoermii. However, it is distinguished from T. zhaoermii in the number of maxillary teeth(15), distance between the two eyes/head width, rostral width/height, mental width/height, in one character limited to female: head width/length, and in four characters restricted to male: occurrence of the reduction from 10 to 8(8 to 6, 6 to 4) scales in each dorsal row on the tail. There are differences in morphology, genetics(mt DNA, n DNA), and geography between the putative new species and T. zhaoermii, the new species meets our proposed eclectic and feasible 'four-differences' rule.Lifang PENG Changhu LU Song HUANG Peng GUO Yaping ZHANG 2014Asian Herpetological Research2014,5,4:4
10The absorption kinetics of Antarctic krill oil phospholipid liposome in blood and the digestive tract of healthy mice by single gavage显示文摘Antarctic krill(Euphausia superba)oil has been gaining increasing attention due to its nutritional and functional potentials.Krill oil usually contains a high concentration(about 50%)of phospholipids(AKOP)rich in DHA and EPA accompanied with 30%–40%triacylglycerols.Phospholipids can be made into liposomes without emulsifiers due to its amphiphilic characteristics.However,the absorption kinetics of AKOP liposome in vivo is not clear,which restrict the molecular mechanism analysis related to its distinct bioactivities.The lipid analysis in serum,small intestinal content and wall was carried out after oral administration of AKOP liposome to illustrate its absorption kinetics in blood and the digestive tract of healthy mice by single gavage.The major type of the obtained AKOP was phosphatidylcholine,and the total contents of the DHA and EPA were 29.31%.AKOP liposome was almost completely digested in the small intestine in 1 h and the hydrolysis products could be quickly absorbed by intestinal enterocytes.The DHA in serum peaked at 2 h after administration of AKOP liposome.AKOP liposome could be quickly digested and absorbed in vivo.The obtained results might provide a scientific basis for the molecular mechanism analysis related to distinct bioactivities of Antarctic krill oil phospholipid.Lin Li Chengcheng Wang Shan Jiang Rong Li Tiantian Zhang Changhu Xue Teruyoshi Yanagita Xiaoming Jiang Yuming Wang 2020Food Science and Human Wellness2020,9,1:4
11Effective Antarctic krill oil extraction using switchable hydrophilicity solvents显示文摘Antarctic krill has been widely studied because of its abundant biomass,rich nutritional value,and great production potential.Notably,krill oil(KO)is rich in phospholipids(PLs),polyunsaturated fatty acids(PUFAs),and astaxanthin.A method based on a green switchable hydrophilicity solvent N,7V-dimethyIcyclohexylamine(DMCHA),which can reversibly change from oil soluble to water soluble in the presence of CO2 was used to extract KO from frozen Antarctic krill as it consumes less energy than traditional methods.We showed that DMCHA destroyed the surface structure of Antarctic krill and accelerated the dissolution of KO.In addition,this method enabled the PL extraction to reach up to 80.2%of total PLs,among which PC accounted for the highest proportion,up to 90.91%in PL.In fact,the astaxanthin extraction reached up to 81.44%of total astaxanthin while the fatty acid(FA)extraction up to 84.35%.The KO extracted through DMCHA was rich in PUFA,up to 47.74%,and the content of EPA+DHA reached 42.16%of total FA content.Furthermore,the amount of residual solvent in the lipid phase was just 0.23%of the DMCHA used for the extraction and the recovery rate of solvent was up to 93.2%.Our results demonstrated the high efficiency of oil extraction and the environmental friendliness of this method.Weiwei Sun Wencan Hua Bowen Shi Changhu Xue Xiaoming Jiang 2020Marine Life Science & Technology2020,2,1:3
12Importance of bird traits for seed dispersal patterns of co-fruiting trees in a patchy forest显示文摘Habitat fragmentation is globally one of the most important drivers of change in biodiversity.Seed dispersal by birds is crucial for tree regeneration in remnant patchy forests,yet how bird traits affect seed dispersal pattern is still poorly understood.We studied the extent to which bird traits affect seed-removal networks and whether these traits affect seed deposition and seedling recruitment for 3 co-fruiting tree species(Taxus chinensis,Cin­namomum bodinieri and Machilus thunbergii)in a patchy forest.A total of 17,18 and 10 bird species were re­corded foraging for seeds of T.chinensis,M.thunbergii and C.bodinieri,respectively.Frequency of bird visi­tation increased with tail length,wing length and body length.Furthermore,bird body length,bill length,body weight and wing length were important in the strength of the seed removal network.During foraging,6 bird species exhibited different patterns of microhabitat utilization and their perching frequency increased with bird weight and tarsus length.As a consequence,frequency of habitat use,bird length and tarsus length were im­portant in determining the number of deposited seeds.For seedling recruitment,seedling number increased with bird tarsus length and weight,but decreased with wing length.Overall,our results showed that various bird traits not only affected seed removal,but also influenced the subsequent processes of seed deposition and seed­ling distribution in a patchy forest.These results thus highlight the importance of large-bodied birds for plant recruitment and point out the need to prioritize the protection and conservation of these birds in remnant patchy forests.Ning LI Zheng WANG Shuai ZHANG Chuan YAN Xinhai LI Changhu LU 2019Integrative Zoology2019,14,5:3
13DEBRIS FLOW CONTROL BY USING SLIT DAMS显示文摘Slit dams have been shown to be effective in trapping coarse sediment and retarding the debris flow. It is necessary to establish the controlling efficiency and the systematic procedures for designing slit dams, as well as reasonable sites for their location. Using the principle of mass conservation and laboratory experiments, this paper develops the sediment flow-out ratio and sediment concentration ratio to evaluate the effectiveness of the slit dam, and confirms that sediment concentration ratio increases with an increase in relative spacing and slit density. The sediment flow-out ratio depends on the sediment concentration ratio and sediment concentration before passing through a slit dam. For sediment concentration before passing through a slit dam, based upon Bagnold’s concept of the dispersive stress generated by grain collisions in flow and bed shear stress, a semi-empirical relationship is obtained. Compared with other researchers’ studies, this study is found to be in excellent conformity with theirs, when taking 0.1 as the empirical coefficient. Besides, height, spacing and location factors affecting a slit dam design for debris flow mitigation are established herein. Furthermore, the design procedures of a slit dam are provided as a useful tool for controlling the debris flow hazards and are illustrated by a numerical example.Hui-Pang LIEN and Fang-Wu TSAI (1 Associate Professor, Department of Hydraulic Engineering, Feng Chia University, Taichung, Taiwan 407, China z Associate Professor, Department of Mechanic Engineering, Chung Chou College of Technology and Commerce, Changhu 2000International Journal of Sediment Research2000,15,4:3
14Effect of enzymatic fish frame protein hydrolysate on freeze-induced denaturation of myofibrillar protein from bighead carp fish (Aristichthys nobilis ) during frozen storage显示文摘薛勇 Xue Changhu Zhang Yongqin Li Zhaojie Gao Ruichang Gao Xin 2006High Technology Letters2006,12,4:2
15An efficient method for chitin production from crab shells by a natural deep eutectic solvent显示文摘Crab shells are an important feedstock for chitin production.However,their highly compact structure significantly limits their use for the production of chitin under mild conditions.Here,a green and efficient approach using a natural deep eutectic solvent(NADES)to produce chitin from crab shells was developed.Its effectiveness in isolating chitin was investigated.The results showed that most proteins and minerals were removed from crab shells and the relative crystallinity of the isolated chitin reached 76%.The quality of the obtained chitin was comparable to chitin isolated by the acid–alkali method.This is the first report on a green method for efficient chitin production from crab shells.This study is expected to open new avenues for green and efficient production of chitin from crab shells.Wen‑Can Huang Dandan Zhao Changhu Xue Xiangzhao Mao 2022Marine Life Science & Technology2022,4,3:2
16Effects of Alginate Gel on Rheological Properties of Hair-tail (Trichiurus lepturus) Surimi显示文摘Effects of alginate gel at different concentrations on rheological properties of hair-tail (Trichiurus lepturus) surimi were investigated. Alginate gel (1% - 3%) exhibited enhanced effects, especially when alginate gel concentration increased. The rheological properties of mixture samples were studied by the time sweep, frequency sweep and temperature sweep. The critical strain values of the mixture samples for the onset of non-linear viscoelasticity were about 5%. The storage modulus G' of the mixture samples increased with time for 4 h. The frequency sweep showed that G' was greater than G' for all the mixture gels with different alginate gel concentrations, and values of both n' and n' for all samples were low (<0.2), these constants corresponding to G' and G', and indicating the elasticity of mixture gels. The values of storage modulus G' decreased during heating process and increased with decreasing temperature.XUE Yong LIU Xin ZHANG Lili LIN Dan XU Jiachao XUE Changhu 2011Journal of Ocean University of China2011,10,2:2
17Identification of Five Sea Cucumber Species Through PCR-RFLP Analysis显示文摘Sea cucumbers are traditional marine food and Chinese medicine in Asia. The rapid expansion of sea cucumber market has resulted in various problems, such as commercial fraud and mislabeling. Conventionally, sea cucumber species could be distinguished by their morphological and anatomical characteristics; however, their identification becomes difficult when they are processed. The aim of this study was to develop a new convenient method of identifying and distinguishing sea cucumber species. Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) analysis of mitochondrial cytochrome oxidase I gene(COI) was used to identifing five sea cucumber species(Apostichopus japonicus, Cucumaria frondosa, Thelenota ananas, Parastichopus californicus and Actinopyga lecanora). A 692 bp fragment of COI was searched for BamHI, KpnI, PstI, XbaI and Eco31 I restriction sites with DNAMAN 6.0, which were then used to PCR-RFLP analysis. These five sea cucumber species can be discriminated from mixed sea cucumbers. The developed PCR-RFLP assay will facilitate the identification of sea cucumbers, making their source tracing and quality controlling feasible.LV Yingchun ZHENG Rong ZUO Tao WANG Yuming LI Zhaojie XUE Yong XUE Changhu TANG Qingjuan 2014Journal of Ocean University of China2014,13,5:2
18Identification of Fucans from Four Species of Sea Cucumber by High Temperature ~1H NMR显示文摘Acidic polysaccharide, which has various biological activities, is one of the most important components of sea cucumber. In the present study, crude polysaccharide was extracted from four species of sea cucumber from three different geographical zones, Pearsonothuria graeffei(Pg) from Indo-Pacific, Holothuria vagabunda(Hv) from Norwegian Coast, Stichopus tremulu(St) from Western Indian Ocean, and Isostichopus badionotu(Ib) from Western Atlantic. The polysaccharide extract was separated and purified with a cellulose DEAE anion-exchange column to obtain corresponding sea cucumber fucans(SC-Fucs). The chemical property of these SC-Fucs, including molecular weight, monosaccharide composition and sulfate content, was determined. Their structure was compared simply with fourier infrared spectrum analyzer and identified with high temperature 1H nuclear magnetic resonance spectrum analyzer(NMR) and room temperature 13 C NMR. The results indicated that Fuc-Pg obtained from the torrid zone mainly contained 2,4-O-disulfated and non-sulfated fucose residue, whereas Fuc-Ib from the temperate zone contained non-, 2-O- and 2,4-O-disulfated fucose residue; Fuc-St from the frigid zone and Fuc-Hv from the torrid zone contained mainly non-sulfated fucose residue. The proton of SC-Fucs was better resolved via high temperature 1H NMR than via room temperature 1H NMR. The fingerprint of sea cucumber in different sea regions was established based on the index of anomer hydrogen signal in SC-Fucs. Further work will help to understand whether there exists a close relationship between the geographical area of sea cucumber and the sulfation pattern of SC-Fucs.WU Nian CHEN Shiguo YE Xingqian LI Guoyun YIN Li'ang XUE Changhu 2014Journal of Ocean University of China2014,13,5:2
19Comparing community birdwatching and professional bird monitoring with implications for avian diversity research: a case study of Suzhou, China显示文摘Background:In the past decades,birdwatching as a hobby developed rapidly and produced ample scientific records that have aided conservation efforts.Therefore,it is increasingly attractive to promote avian research by providing data from birdwatching.Methods:We compared records from 16 years of community birdwatching and a 1-year formalized bird monitoring in Suzhou,China to study the similarities and differences between the two monitoring methods.Results:We showed that within the 325 bird species recorded by the two methods,an annual average of 108 species were documented by community science and 223 bird species were recorded by 1-year formalized monitoring.Measured by the number of bird species recorded per survey trip,the bird monitoring activity of community birdwatchers was significantly lower.Furthermore,the monitoring intensity of community birdwatching measured as the average survey trips per site each survey year was also lower than that of formalized bird monitoring.In addition,community birdwatchers preferred urban landscapes to rural areas.Conclusions:Community birdwatching could record the majority of local birds and complements the professional surveys in avian research.Well designed and coordinated community science can be used to expand the knowledge about avian distribution and population dynamics.These findings are critical for the development of conservation science with regard to community involvement.Yan Zhou Anping Chen Jenny QOuyang Yanlin Liu Aiyu Zheng Zaixi Yang Yong Zhang Bin Wang Yifei Jia Shengwu Jiao Qing Zeng Changhu Lu 2020Avian Research2020,11,2:2
20Long-Term Effects of Docosahexaenoic Acid-Bound Phospholipids and the Combination of Docosahexaenoic Acid-Bound Triglyceride and Egg Yolk Phospholipid on Lipid Metabolism in Mice显示文摘The bioavailability of docosahexaenoic acid(DHA) and eicosapentaenoic acid(EPA) depends on their chemical forms. This study investigated the long-term effects of DHA-bound triglyceride(TG-DHA), DHA-bound phospholipid(PL-DHA), and the combination of TG-DHA and egg yolk phospholipid(Egg-PL) on lipid metabolism in mice fed with a high-fat diet(fat levels of 22.5%). Male C57BL/6J mice were fed with different formulations containing 0.5% DHA, including TG-DHA, PL-DHA, and the combination of TG-DHA and Egg-PL, for 6 weeks. Serum, hepatic, and cerebral lipid concentrations and the fatty acid compositions of the liver and brain were determined. The concentrations of serum total triglyceride(TG), total cholesterol(TC), high-density lipoprotein cholesterol(HDL-c), and hepatic TG in the PL-DHA group and the combination group were significantly lower than those in the high-fat(HF) group(P < 0.05). Atherogenic index(AI) of the PL-DHA group was significantly lower than that of the combination group(P < 0.05). Hepatic TC level in the combination group was significantly lower than that in the HF group(P < 0.05), but no significant difference was observed between the combination group and the PL-DHA group. Both the PL-DHA and the combination groups showed significantly increased DHA levels in the liver compared with the HF group(P < 0.05). However, there were no obvious increases in the cerebral DHA levels in all DHA diet groups. These results suggest that PL-DHA was superior to the combination of TG-DHA and Egg-PL in decreasing the AI. Long-term dietary supplementation with low amount of DHA(0.5%) may improve hepatic DHA levels, although cerebral DHA levels may not be enhanced.CHE Hongxia CUI Jie WEN Min XU Jie Teruyoshi Yanagita WANG Qi XUE Changhu WANG Yuming 2018Journal of Ocean University of China2018,17,2:2
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