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| 1 | Cigarette Smoking Increases Risk for Incident Metabolic Syndrome in Chinese Men—Shanghai Diabetes Study显示文摘Objective To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.Methods A total of 693 men with no MetS at baseline were followed for 2.9‐5.5 years.Subjects were divided into nonsmokers,ex‐smokers,and current smokers according to baseline smoking status.Results After adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR index,and BMI at baseline and weight change,current smokers were dose‐dependently associated with increased risk for developing new MetS compared with nonsmokers.The odds ratio (OR) was 2.131 (95% CI,1.264,3.592;P<0.01) for the NCEPIII definition or 3.083 (95% CI,1.807,5.295;P<0.01) for the JCDCG definition of MetS.Ex‐smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition.Compared with nonsmokers,current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL‐C.Conclusion Smoking is a risk factor for developing MetS in Chinese men after adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR,BMI,and weight change.This could be due to an increased incidence of dyslipidemia.Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition. | ZHU YunXia ZHANG MingLiang HOU XuHong LU JunXi PENG LiangPu GU HuiLin WANG Chen JIA WeiPing | 2011 | Biomedical and Environmental Sciences2011，24，5： | 13 |
| 2 | Adipocyte-derived microvesicles from obese mice induce M1 macrophage phenotype through secreted miR-155显示文摘The pro-inflammatory profile of M1 macrophage accumulation in adipose tissue is a central event leading to the metabolic complications of obesity.However,the mechanisms by which M1 macrophages are enriched in adipose tissue during weight gain remain incompletely understood.Here,we investigated the effects of adipocyte-derived microvesicles(ADM)on modulating macrophage phenotype in mice and explored the involved molecular signalling pathways.We found that,compared with ADM from lean mice(SD ADM),ADM from obese mice(HFD ADM)significantly enhanced M1 marker expression.The quantitative RTPCR assay demonstrated that miR-155 was upregulated in both HFD ADM and HFD ADM-treated macrophages.By depleting miR-155 expression in HFD ADM and increasing miR-155 level in SD ADM,we further illustrated that miR-155 in ADM-induced M1 macrophage polarization.Functionally,in contrast to SD ADM,HFD ADM significantly decreased the protein level of SOCS1,a proven miR-155 target,leading to activation of STAT1,and suppression of STAT6 signalling;these effects were reversed by silencing miR-155 in HFD ADM.Furthermore,the supernatant of bone marrow-derived macrophages pre-stimulated with miR-155-bearing ADM interfered with insulin signalling and insulin-induced glucose uptake in adipocytes.Collectively,these results provide the first evidence that M1 macrophage polarization can be mediated by miR-155-bearing ADM,which reciprocally regulates insulin signalling and glucose uptake in adipocytes.Our study reveals a novel mechanism through which obesity induces an imbalance in the M1-to-M2 macrophage ratio in adipose tissue,thus causing chronic inflammation and local insulin resistance. | Yaqin Zhang Hongliang Mei Xiaoai Chang Fang Chen Yunxia Zhu Xiao Han | 2016 | Journal of Molecular Cell Biology2016，8，6： | 11 |
| 3 | Coupling behavior between adhesive and abrasive wear mechanism of aero-hydraulic spool valves显示文摘Leakage due to wear is one of the main failure modes of aero-hydraulic spool valves.This paper established a practical coupling wear model for aero-hydraulic spool valves based on dynamic system modelling theory. Firstly, the experiment for wear mechanism verification proved that adhesive wear and abrasive wear did coexist during the working process of spool valves. Secondly coupling behavior of each wear mechanism was characterized by analyzing actual timevariation of model parameters during wear evolution process. Meanwhile, Archard model and three-body abrasive wear model were utilized for adhesive wear and abrasive wear, respectively.Furthermore, their coupling wear model was established by calculating the actual wear volume.Finally, from the result of formal test, all the required parameters for our model were obtained.The relative error between model prediction and data of pre-test was also presented to verify the accuracy of model, which demonstrated that our model was useful for providing accurate prediction of spool valve's wear life. | Chen Yunxia Gong Wenjun Kang Rui | 2016 | Chinese Journal of Aeronautics2016，29，4： | 10 |
| 4 | Model-driven degradation modeling approaches:Investigation and review显示文摘The second law of thermodynamics implies that any animate and inanimate systems degrade and inevitably stops functioning.It is irreversible over time that can be labeled as‘‘the degradation arrow of time'.From perspective of products’reliability design,it is essential to build appropriate models of describing the degradation arrow of time.The current modeling approaches mainly include the model-driven(having assumed forms based on cognitive experience of mankind)and data-driven(using data learning techniques without form hypothesis)approaches.In this paper,we just investigate and review the model-driven degradation approaches,hoping to provide suggestions of the model construction or selection for scholars or engineers.First,for the single mechanism,degradation law models and stochastic process models are classified as separately depicting the tendency and fluctuation of degradation.For the degradation law model,we propose the concept of meta-models as original types for various personal models.For the stochastic process model,two main types including the non-monotonic and monotonical types are presented.Then,four multi-mechanism degradation types are discussed,that are competitive degradation,multi-stage degradation,coexistence of degradation and impact,and coexistence of degradation and failure.Besides,for the multi-performance degradation,independent and coupling models are introduced.The forms,connotations,applicability and insufficiency of these models are described with a series of examples from the literature and our own experiences.The final explicit suggestions about the potential future work are provided for the development of new degradation models. | Rui KANG Wenjun GONG Yunxia CHEN | 2020 | Chinese Journal of Aeronautics2020，33，4： | 9 |
| 5 | Using PoF models to predict system reliability considering failure collaboration显示文摘Existing Physics-of-Failure-based(PoF-based) system reliability prediction methods are grounded on the independence assumption, which overlooks the dependency among the components. In this paper, a new type of dependency, referred to as failure collaboration, is introduced and considered in reliability predictions. A Po F-based model is developed to describe the failure behavior of systems subject to failure collaboration. Based on the developed model, the Bisection-based Reliability Analysis Method(BRAM) is exploited to calculate the system reliability. The developed methods are applied to predicting the reliability of a Hydraulic Servo Actuator(HSA). The results demonstrate that the developed methods outperform the traditional Po F-based reliability prediction methods when applied to systems subject to failure collaboration. | Zeng Zhiguo Kang Rui Chen Yunxia | 2016 | Chinese Journal of Aeronautics2016，29，5： | 8 |
| 6 | Dietary supplementation with a high dose of daidzein enhances the antioxidant capacity in swine muscle but experts pro-oxidant function in liver and fat tissues显示文摘Background: Although isoflavones are natural dietary antioxidants, they may have toxicological effects. This study aimed to evaluate the redox system in tissues of finishing pigs by supplementation with high dose of daidzein(640 mg/kg).Results: The supplementation of high dose of daidzein for 64 d increased the activity of superoxide dismutase and total antioxidant capacity in longissimus muscle but down-regulated the expression of reactive oxygen species(ROS)-producing enzyme NADPH oxidase-2 and cyclooxygenase-2. In contrast, high-level supplementation with daidzein exerted pro-oxidant changes in back fat, abdominal fat, liver, and plasma, as reflected by increased contents of malondialdehyde, a lipid peroxidation product, in these tissues. Furthermore, daidzein supplementation resulted in higher expression of ROS-producing enzymes, including NADPH oxidase-1 and cyclooxygenase-1in liver, 5-lipoxygenase(5-LOX) in backfat and NADPH oxidase-2 both in abdominal fat and backfat. The supplementation of daidzein did not affect meat quality parameters in longissimus muscle, including marbling score,eye muscle areas, intramuscular fat, shear force, drip loss, p H and meat color.Conclusions: This experiment suggests that dietary supplementation of finishing pigs with daidzein at a high dose level improves redox status in muscle but exerts pro-oxidant effect in liver and fat tissues. | Wei Chen Xianyong Ma Yingcai Lin Yunxia Xiong Chuntian Zheng Youjun Hu Deqian Yu Zongyong Jiang | 2016 | Journal of Animal Science and Biotechnology2016，7，3： | 8 |
| 7 | Methods to determine stress profile in ALT based on theoretical life models显示文摘With the recent products being more reliable,engineers cannot obtain enough failure or degradation information through the design period and even the product lifetime,therefore,accelerated life test(ALT)has become the most popular way to quantify the life characteristics of products.Test design is the most essential topic,such as testing duration,stress profile,data inference,etc.In this paper,a method and procedure based on theoretical life models is proposed to determine the accelerated stress profile.Firstly,the method for theoretical life calculation is put forward based on the main failure mechanism analysis and the theoretical life models.Secondly,the method is provided to determine the accelerated stress profile,including the method to determine the accelerated stress types and the stress range on the basis of the main failure mechanism analysis,the method to determine the acceleration factor and the accelerated stress level based on life quantitative calculation models,and the collaborative analysis method of the accelerated test time while taking the multiple failure mechanisms into consideration.Lastly,the actuator is taken as an example to describe the procedure of the method and the engineering applicability and the validity are verified. | Chen Yunxia Jing Hailong Liao Xun Kang Rui | 2015 | Chinese Journal of Aeronautics2015，28，3： | 7 |
| 8 | Transferrin receptor and ferritin-H are developmentally regulated in oligodendrocyte lineage cells显示文摘Iron is an essential trophic element that is required for cell viability and differentiation, especially in oligodendrocytes, which consume relatively high rates of energy to produce myelin. Multiple iron metabolism proteins are expressed in the brain including transferrin receptor and ferritin-H. However, it is still unknown whether they are developmentally regulated in oligodendrocyte lineage cells for myelination. Here, using an in vitro cultured differentiation model of oligodendrocytes, we found that both transferrin receptor and ferritin-H are significantly upregulated during oligodendrocyte maturation, implying the essential role of iron in the development of oligodendrocytes. Additional different doses of Fe3+ in the cultured medium did not affect oligodendrocyte precursor cell maturation or ferritin-H expression but decreased the expression of the transferrin receptor. These results indicate that upregulation of both transferrin receptor and ferritin-H contributes to maturation and myelination of oligodendrocyte precursor cells. | Yunxia Li Qiang Guan Yuhui Chen Hongjie Han Wuchao Liu Zhiyu Nie | 2013 | Neural Regeneration Research2013，8，1： | 7 |
| 9 | Production and contribution of hydroxyl radicals between the DSA anode and water interface显示文摘Hydroxyl radicals play the key role during electrochemical oxidation and photoelectrochemical oxidation. The production and effect of hydroxyl radicals on the interface between DSA anode and water was investigated by examining the quenching effect of iso-propanol on Orange II decolorization. We observed that with an increase in electrode potential from 4 to 12 V across electrodes at pH 7.0, the contribution percentage of hydroxyl radicals increased dramatically. More OH radicals were produced in acidic and alkaline conditions than at neutral conditions. At electrode potential of 4 V, the contribution percentage of hydroxyl radicals was obviously higher at near neutral pH conditions, while removal efficiency of Orange II achieved was the lowest concurrently. Finally, for photocatalytic oxidation, electrochemical oxidation, and photoelectrochemical oxidation using the same DSA electrode, the effect of hydroxyl radicals proved to be dominant in photocatalytic oxidation but the contribution of hydroxyl radicals was not dominant in electrochemical oxidation, which implies the necessity of UV irradiation for electrochemical oxidation during water treatment. | Guoting Li Meiya Zhu Jing Chen Yunxia Li Xiwang Zhang | 2011 | Journal of Environmental Sciences2011，23，5： | 6 |
| 10 | An indicator-guided photo-controlled drug delivery system based on mesoporous silica/gold nanocomposites显示文摘mesoporous 硅石 / 黄金(MSN/Au ) nanocomposite 为明确地目标为肿瘤房间的控制相片的药交货被设计。MSN/Au nanocomposite 由基于 MSN 的药搬运人组成,金 nanoparticle (AuNP ) 基于指示物。当基于 MSN 的药搬运人是 mesoporous 硅石时, nanoparticle 与相片可切换的偶氮苯使不能调动(偶氮) 一半,基于 AuNP 的指示物是与矩阵 metalloproteinase (MMP ) 修改的熄灭荧光的 AuNP 底层并且 poly (乙烯乙二醇) 。二种 nanoparticles 被连接由一, cyclodextrin (, CD ) 更暗淡的桥牌。在 vitro,研究证明 nanocomposite 明确地与肿瘤地点 overexpressing MMP-2 交往了,为释放的随后的紫外轻照耀的启用的指导它骗诱药。通过基于 AuNP 的指示物和基于 MSN 的药搬运人的集成, MSN/Au nanocomposite 能精确本地化释放的药到肿瘤地点,显著地从而改进治疗学的功效。 | Guofeng Luo Weihai Chen Huizhen Jia Yunxia Sun Han Cheng Renxi Zhuo Xianzheng Zhang | 2015 | Nano Research2015，8，6： | 6 |
| 11 | Arsenic uptake, accumulation and phytofiltration by duckweed (Spirodela polyrhiza L.)显示文摘This study investigates arsenic (As) accumulation and tolerance of duckweed Spirodela polyrhiza L. and its potential for As phytofiltration. S. polyrhiza was able to survive in high concentration of As(V) solution. The EC 50 values (± SE) based on the external As(V) were (181.66 ± 20.12) μmol/L. It accumulated (999 ± 95) mg As/kg dw when exposed in 320 μmol/L As(V) solution for one week, and was able to take up appropriately 400 mg As/kg dw in tissues without a significant biomass loss. The EC 50 values (the effective concentration of As(V) in the nutrient solution that caused a 50% inhibition on biomass production) was (866 ± 68) mg/kg dw for the tissues, indicating that S. polyrhiza had a high capability of As accumulation and tolerance. The uptake kinetic parameters V max was (55.33 ± 2.24) nmol/(g dw·min) and K m was (0.144 ± 0.011) mmol/L. Within 72 hr, S. polyrhiza decreased As concentration in the solution from 190 to 113 ng/mL with a removal rate of 41%. The study suggested that this floating aquatic plant has some potential for As phytofiltration in contaminated water bodies or paddy soils. | Xin Zhang Ying Hu Yunxia Liu Baodong Chen | 2011 | Journal of Environmental Sciences2011，23，4： | 5 |
| 12 | Primary resistance to crizotinib treatment in a non-small cell lung cancer patient with an EML4-ALK rearrangement:a case report显示文摘Crizotinib,a small molecular tyrosine kinase inhibitor,manifests dramatic responses in patients with non-small cell lung cancer with echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase(EML4-ALK)rearrangements.ALK gene point mutation is the primary mechanism of acquired crizotinib resistance;however,the intrinsic mechanism is not fully understood.Here,we report a patient with a low mutant allele fraction(MAF)of EML4-ALK rearrangement,who experienced primary resistance to crizotinib treatment.The patient was a 66-year-old Chinese man,who had a history of metastatic lung cancer and was treated with first-and third-generation epidermal growth factor receptor tyrosine kinase inhibitors(EGFR TKIs).After 14 months of osimertinib treatment,his disease progressed,and next-generation sequencing was performed from a liquid biopsy of the patient’s blood.An EML4-ALK rearrangement was found and crizotinib was administered.The patient’s lung lesions continued to progress after one month of crizotinib treatment,and pemetrexed-bevacizumab was initiated.After two cycles of chemotherapy,the metastatic cancers shrunk,and the patient maintained stable disease at his last follow-up.EML4-ALK rearrangements can happen in patients with EGFR-positive NSCLC,after acquired resistance to EGFR TKI treatment.The EGFR T790M and C797G mutations occur in cis is a critical mechanism of resistance to osimertinib therapy.The MAF of EML4-ALK rearrangements in cancer cells might be a predictive factor for crizotinib treatment. | Ling Zhang Yunxia Li Shaohong Zhang Chen Gao Keke Nie Youxin Ji | 2018 | Cancer Biology & Medicine2018，15，2： | 5 |
| 13 | Hemodynamic monitoring and management of patients undergoing high-risk surgery:a survey among Chinese anesthesiologists显示文摘Hemodynamic monitoring and optimization improve postoperative outcome during high-risk surgery.However,hemodynamic management practices among Chinese anesthesiologists are largely unknown.This study sought to evaluate the current intraoperative hemodynamic management practices for high-risk surgery patients in China.From September 2010 to November 2011,we surveyed anesthesiologists working in the operating rooms of 265 hospitals representing 28 Chinese provinces.All questionnaires were distributed to department chairs of anesthesiology or practicing anesthesiologists.Once completed,the 29-item questionnaires were collected and analyzed.Two hundred and 10 questionnaires from 265 hospitals in China were collected.We found that 91.4%of anesthesiologists monitored invasive arterial pressure,82.9%monitored central venous pressure(CVP),13.3%monitored cardiac output(CO),10.5%monitored mixed venous saturation,and less than 2%monitored pulse pressure variation(PPV) or systolic pressure variation(SPV) during high-risk surgery.The majority(88%) of anesthesiologists relied on clinical experience as an indicator for volume expansion and more than 80%relied on blood pressure,CVP and urine output.Anesthesiologists in China do not own enough attention on hemodynamic parameters such as PPV,SPV and CO during fluid management in high-risk surgical patients.The lack of CO monitoring may be attributed largely to the limited access to technologies,the cost of the devices and the lack of education on how to use them.There is a need for improving access to these technologies as well as an opportunity to create guidelines and education for hemodynamic optimization in China. | Guo Chen Yunxia Zuo Lei Yang Elena Chung Maxime Cannesson | 2014 | The Journal of Biomedical Research2014，28，5： | 4 |
| 14 | Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion显示文摘Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium(CM) and fluid flow-treated conditioned medium(FFCM) with 0.25 Pa and 1 Pa shear stress. Notably, CM and FFCM at 0.25 Pa induced the mesenchymal-to-epithelial transition(MET), but FFCM at 1 Pa induced the epithelial-to-mesenchymal transition(EMT). This suggested that the effects of fluid flow on conditioned media depend on flow intensity. Fluorescence resonance energy transfer(FRET)-based evaluation of Src activity and vinculin molecular force showed that osteopontin was involved in EMT and MET switching. A mouse model of tumorinduced osteolysis was tested using dynamic tibia loadings of 1, 2, and 5 N. The low 1 N loading suppressed tumor-induced osteolysis, but this beneficial effect was lost and reversed with loads at 2 and 5 N, respectively. Changing the loading intensities in vivo also led to changes in serum TGFβ levels and the composition of tumor-associated volatile organic compounds in the urine.Collectively, this study demonstrated the critical role of intensity-dependent mechanotransduction and osteopontin in tumorosteocyte communication, indicating that a biophysical factor can tangibly alter the behaviors of tumor cells in the bone microenvironment. | Yao Fan Aydin Jalali Andy Chen Xinyu Zhao Shengzhi Liu Meghana Teli Yunxia Guo Fangjia Li Junrui Li Amanda Siegel Lianxiang Yang Jing Liu Sungsoo Na Mangilal Agarwal Alexander G.Robling Harikrishna Nakshatri Bai-Yan Li Hiroki Yokota | 2020 | Bone Research2020，8，2： | 4 |
| 15 | Growth and metal uptake of energy sugarcane (Saccharum spp.) in different metal mine tailings with soil amendments显示文摘A pot experiment was conducted to investigate the feasibility of growing energy sugarcane(Saccharum spp.) in three different metal mine tailings(Cu, Sn and Pb/Zn tailings) amended with uncontaminated soil at different mixing ratios. The results indicated that sugarcane was highly tolerant to tailing environments. Amendments of 20% soil to Sn tailings and 30% soil to Cu tailings could increase the biomass of cane-stem for use as the raw material for bioethanol production. Heavy metals were mostly retained in roots, which indicated that sugarcane was useful for the stabilization of the tailings. Bagasse and juice, as the most valuable parts to produce bioethanol, only accounted for 0.6%– 3% and 0.6%–7% of the total metal content. Our study supported the potential use of sugarcane for tailing phytostabilization and bioenergy production. | Xin Zhang Yongguan Zhu Yuebin Zhang Yunxia Liu Shaochun Liu Jiawen Guo Rudan Li Songlin Wu Baodong Chen | 2014 | Journal of Environmental Sciences2014，26，5： | 4 |
| 16 | A compositional method to model dependent failure behavior based on PoF models显示文摘In this paper, a new method is developed to model dependent failure behavior among failure mechanisms. Unlike the existing methods, the developed method models the root cause of the dependency explicitly, so that a deterministic model, rather than a probabilistic one, can be established. Three steps comprise the developed method. First, physics-of-failure(PoF) models are utilized to model each failure mechanism. Then, interactions among failure mechanisms are modeled as a combination of three basic relations, competition, superposition and coupling. This is the reason why the method is referred to as ‘‘compositional method'. Finally, the PoF models and the interaction model are combined to develop a deterministic model of the dependent failure behavior. As a demonstration, the method is applied on an actual spool and the developed failure behavior model is validated by a wear test. The result demonstrates that the compositional method is an effective way to model dependent failure behavior. | Zhiguo ZENG Yunxia CHEN Enrico ZIO Rui KANG | 2017 | Chinese Journal of Aeronautics2017，30，5： | 4 |
| 17 | MicroRNA-142-3p is frequently upregulated in colorectal cancer and may be involved in the regulation of cell proliferation显示文摘MicroRNAs are small single-stranded RNA molecules consisting of approximately 22 nucleotides (nt), and have post-transcriptional regulatory functions. By gene chip screening, we previously showed that miR-142-3p was significantly upregulated in colorectal cancer tissue and was associated with clinicopathological features, compared with matched non-tumor tissue. In this study, we confirmed significant upregulation of miR-142-3p in 60 colorectal cancer samples and three colorectal cancer cell lines by quantitative real-time PCR (qRT-PCR). Using software and network resources, we predicted TCF7 as a target of miR-142-3p, which we confirmed with dual-luciferase assays. By RT-PCR and Western blot analysis, we found miR-142-3p negatively regulates TCF7 expression post-transcriptionally. CCK8 assays and growth curves indicated that overexpression of miR-142-3p in SW480 colorectal cancer cells potently inhibited cell proliferation in vitro. The expression of TCF7 mRNA and protein was upregulated in both colorectal cancer tissues and colorectal cancer cell lines, closely correlating with its function as an oncogene in promoting tumor cell proliferation and inhibiting apoptosis. With TCF7 as a direct target, our results suggested that miR-142-3p may be involved in the regulation of cell proliferation in colorectal cancer. | ZHOU JiaLiang JIANG Zhi WANG ZhengWu ZOU ShiTao ZHANG YunXia CAI Wei WANG MingZhi XU Min SHI DongTao CHEN WeiChang | 2013 | Chinese Science Bulletin2013，58，23： | 4 |
| 18 | Long-term stable silver nanowire transparent composite as bottom electrode for perovskite solar cells显示文摘作为传统的铟听氧化物(ITO ) 的最有希望的选择,银 nanowire (AgNW ) 有改进稳定性的合成透明电极在各种各样的设备与太古的 AgNWs 网络的相比被表明了。然而,象为 perovskite 太阳能电池的底部电极合成的稳定的 AgNW/polymer 还没被报导了。这里,与修改抗氧化剂的 chitosan 聚合物合成的长期的稳定的、光滑的 AgNW 被开发。修改聚合物能有效地与 perovskite 保护太古的 AgNWs 免受方面反应的伤害,而它不通过绝缘的聚合物的接口堵住搬运人飘移。同样准备的 AgNW/polymer 合成电极在 50 m 的一种扫描尺寸在 10 nm 下面展出了根平均数平方粗糙 ????? | Yunxia Jin Yong Sun Kaiqing Wang Yani Chen Ziqi Liang Yuxi Xu Fei Xiao | 2018 | Nano Research2018，11，4： | 4 |
| 19 | Convergence Analysis of the Legendre Spectral Collocation Methods for Second Order Volterra Integro-Differential Equations显示文摘A class of numerical methods is developed for second order Volterra integrodifferential equations by using a Legendre spectral approach.We provide a rigorous error analysis for the proposed methods,which shows that the numerical errors decay exponentially in the L∞-norm and L2-norm.Numerical examples illustrate the convergence and effectiveness of the numerical methods. | Yunxia Wei Yanping Chen | 2011 | Numerical Mathematics(Theory,Methods and Applications)2011，4，3： | 3 |
| 20 | Preparation and tribological properties of Sol-Gel TiO_2-ZrO_2 composite thin films显示文摘High oriented TiO2-ZrO2 composite thin films on Si (100) and glass sheet were suc-cessfully prepared by sol-gel process followed by dip-coating the ethanol solution of zirconiumoxychloride and titanium tetrachloride. The sol-gel process, microstructure, morphology and tri-bological properties of TiO2 -ZrO2 films were investigated using TGA, DSC, XPS, XRD, AFM anddynamic-static tribometer. The results show that the TiO2-ZrO2films are dense, homogeneous andat a complete tetragonal phase with an excellent antiwear and friction reduction performance. Un-der 0.5N applied load, the friction coefficient is 0.14-0.20 and the antiwear life is more than 5000sliding cycles for both TiO2-ZrO2/ AISI 52100 steel and TiO2-ZrO2/ Si3N4. SEM observation sug-gests that wear mechanism of TiO2 -ZrO2 composite film under low load was fatigue wear, andunder high load was adhesive wear. The TiO2 -ZrO2 films show potential applications as coatingsfor antiwear and friction reduction under the harsh condition. | CHEN Yunxia ZHOU Jinfang LIU Weimin State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical, Physics, Chinese Academy of Sciences, Lanzhou 730000, China | 2001 | Science China Mathematics2001，44，S1： | 3 |
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