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| 1 | Multi-dimension apportionment of clean air “parade blue”phenomenon in Beijing显示文摘The mass concentration and major chemical components of fine particulate matter were measured before,during and after Beijing's massive parade commemorating 70th anniversary of the Chinese Victory in World War II on September 3,2015.Regional emission inventory,positive matrix factorization(PMF),observations from space and backward air mass trajectories were jointly applied to identify the major pollution sources and their temporal and spatial variations.The contributions of emissions variations and the meteorological conditions related to the'parade blue'phenomenon in Beijing and its surrounding areas were investigated in detail.The main cause of the decreased PM_(2.5)mass concentration was attributed to the absolute reduction in emissions of primary air pollutants.The chemical composition of PM_(2.5)varied significantly before,during and after the parade.Fugitive dust particles were well controlled,the secondary formation of PM_(2.5)was reduced along with the controlled gaseous precursors'emissions from vehicles and industrial sources during the temporary intensified control period.During the parade period,the SO_2and NO_2column concentrations in Beijing and the surrounding areas decreased sharply,indicating that the coordinated reduction in primary emissions from the surrounding areas of Beijing played an important role in lowering the ambient concentration of SO_2and NO_2and accordingly lowered PM_(2.5)and improved the regional air quality.A comparison of the temperature,humidity,and wind speed and direction during the same periods in 2014 and 2015 showed that the meteorological conditions positively influenced the achievement of'parade blue'. | Yifeng Xue Yong Wang Xuefeng Li Hezhong Tian Lei Nie Xiaoqing Wu Junrui Zhou Zhen Zhou | 2018 | Journal of Environmental Sciences2018，30，3： | 5 |
| 2 | Multi-perspective digital image correlation method using a single color camera显示文摘A novel 3 D digital image correlation(DIC) system based on a single three charge-couple device(3 CCD) color camera is proposed in this paper. Images from three different perspectives are captured by a 3 CCD camera using a reflective-based pseudo-vision system. These images are then separated by the different CCD channels, and the correlation algorithm for the multi-camera DIC system is adopted to evaluate the images. Compared to the conventional multi-camera DIC system, the proposed system is much more compact. In addition, the proposed system has no loss of spatial resolution, compares to the traditional single camera DIC system. The complex surface measurement ability and the measurement accuracy is significantly improved through the use of the multi-camera DIC algorithm. The principle of the proposed system is described in detail as well as the experimental setup. A series of validation tests are performed, and the results are verified with the commercial 3 D-DIC system. | WANG YongHong DAN XiZuo LI JunRui WU SiJin YANG LianXiang | 2018 | Science China(Technological Sciences)2018，61，1： | 5 |
| 3 | A novel layout for single event upset mitigation in advanced CMOS SRAM cells显示文摘A novel layout has been proposed to reduce the single event upset(SEU) vulnerability of SRAM cells.Extensive 3-D technology computer-aided design(TCAD) simulation analyses show that the proposed layout can recover the upset-state much easier than conventional layout for larger space of PMOS transistors.For the angle incidence,the proposed layout is immune from ion hit in two plans,and is more robust against SEU in other two plans than the conventional one.The ability of anti-SEU is enhanced by at least 33% while the area cost reduced by 47%.Consequently,the layout strategy proposed can gain both reliability and area cost benefit simultaneously. | QIN JunRui LI DaWei CHEN ShuMing | 2013 | Science China(Technological Sciences)2013，56，1： | 4 |
| 4 | Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion显示文摘Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium(CM) and fluid flow-treated conditioned medium(FFCM) with 0.25 Pa and 1 Pa shear stress. Notably, CM and FFCM at 0.25 Pa induced the mesenchymal-to-epithelial transition(MET), but FFCM at 1 Pa induced the epithelial-to-mesenchymal transition(EMT). This suggested that the effects of fluid flow on conditioned media depend on flow intensity. Fluorescence resonance energy transfer(FRET)-based evaluation of Src activity and vinculin molecular force showed that osteopontin was involved in EMT and MET switching. A mouse model of tumorinduced osteolysis was tested using dynamic tibia loadings of 1, 2, and 5 N. The low 1 N loading suppressed tumor-induced osteolysis, but this beneficial effect was lost and reversed with loads at 2 and 5 N, respectively. Changing the loading intensities in vivo also led to changes in serum TGFβ levels and the composition of tumor-associated volatile organic compounds in the urine.Collectively, this study demonstrated the critical role of intensity-dependent mechanotransduction and osteopontin in tumorosteocyte communication, indicating that a biophysical factor can tangibly alter the behaviors of tumor cells in the bone microenvironment. | Yao Fan Aydin Jalali Andy Chen Xinyu Zhao Shengzhi Liu Meghana Teli Yunxia Guo Fangjia Li Junrui Li Amanda Siegel Lianxiang Yang Jing Liu Sungsoo Na Mangilal Agarwal Alexander G.Robling Harikrishna Nakshatri Bai-Yan Li Hiroki Yokota | 2020 | Bone Research2020，8，2： | 4 |
| 5 | Establishment of an optimized CTC detection model consisting of EpCAM,MUC1 and WT1 in epithelial ovarian cancer and its correlation with clinical characteristics显示文摘Objective:Emerging studies have demonstrated the promising clinical value of circulating tumor cells(CTCs)for diagnosis,disease assessment,treatment monitoring and prognosis in epithelial ovarian cancer.However,the clinical application of CTC remains restricted due to diverse detection techniques with variable sensitivity and specificity and a lack of common standards.Methods:We enrolled 160 patients with epithelial ovarian cancer as the experimental group,and 90 patients including 50 patients with benign ovarian tumor and 40 healthy females as the control group.We enriched CTCs with immunomagnetic beads targeting two epithelial cell surface antigens(EpCAM and MUC1),and used multiple reverse transcription-polymerase chain reaction(RT-PCR)detecting three markers(EpCAM,MUC1 and WT1)for quantification.And then we used a binary logistic regression analysis and focused on EpCAM,MUC1 and WT1 to establish an optimized CTC detection model.Results:The sensitivity and specificity of the optimized model is 79.4%and 92.2%,respectively.The specificity of the CTC detection model is significantly higher than CA125(92.2%vs.82.2%,P=0.044),and the detection rate of CTCs was higher than the positive rate of CA125(74.5%vs.58.2%,P=0.069)in early-stage patients(stage I and II).The detection rate of CTCs was significantly higher in patients with ascitic volume≥500 mL,suboptimal cytoreductive surgery and elevated serum CA125 level after 2 courses of chemotherapy(P<0.05).The detection rate of CTC;and CTC;was significantly higher in chemo-resistant patients(26.3%vs.11.9%;26.4%vs.13.4%,P<0.05).The median progression-free survival time for CTC;patients trended to be longer than CTC;patients,and overall survival was shorter in CTC;patients(P=0.043).Conclusions:Our study presents an optimized detection model for CTCs,which consists of the expression levels of three markers(EpCAM,MUC1 and WT1).In comparison with CA125,our model has high specificity and demonstrates better diagnostic values,especially for early-stage ovarian cancer.Detection of CTC;and CTC;had predictive value for chemotherapy resistance,and the detection of CTC;suggested poor prognosis. | Tongxia Wang Yan Gao Xi Wang Junrui Tian Yuan Li Bo Yu Cuiyu Huang Hui Li Huamao Liang David M.Irwin Huanran Tan Hongyan Guo | 2022 | Chinese Journal of Cancer Research2022，34，2： | 2 |
| 6 | Nonfunctional alleles of long-day suppressor genes independently regulate flowering time显示文摘Due to the remarkable adaptability to various environments, rice varieties with diverse flowering times have abeen domesticated or improved from Oryza rufipogon.Detailed knowledge of the genetic factors controlling flowering time will facilitate understanding the adaptation mechanism in cultivated rice and enable breeders to design appropriate genotypes for distinct preferences. In this study,four genes(Hd1, DTH8, Ghd7 and OsPRR37) in a rice long-day suppression pathway were collected and sequenced in 154, 74,69 and 62 varieties of cultivated rice(Oryza sativa)respectively. Under long-day conditions, varieties with nonfunctional alleles flowered significantly earlier than those with functional alleles. However, the four genes have different genetic effects in the regulation of flowering time: Hd1 and Os PRR37 are major genes that generally regulate rice flowering time for all varieties, while DTH8 and Ghd7 only regulate regional rice varieties. Geographic analysis and network studies suggested that the nonfunctional alleles of these suppression loci with regional adaptability were derived recently and independently. Alleles with regional adaptability should be taken into consideration for genetic improvement. The rich genetic variations in these four genes,which adapt rice to different environments, provide the flexibility needed for breeding rice varieties with diverse flowering times. | Xiao-Ming Zheng Li Feng Junrui Wang Weihua Qiao Lifang Zhang Yunlian Cheng Qingwen Yang | 2016 | Journal of Integrative Plant Biology2016，58，6： | 2 |
| 7 | High-resolution cryo-EM structure of the proteasome in complex with ADP-AIFx显示文摘 | Zhanyu Ding Zhenglin Fu Cong Xu Yifan Wang Yanxing Wang Junrui Li Liangliang Kong Jinhuan Chen Na Li Rongguang Zhang Yao Cong | 2017 | Cell Research2017，27，3： | 1 |
| 8 | Coupled seepage and stress fields in roller compacted concrete dam显示文摘 | CHAI Junrui LI Kanghong WU Yanqing | 2005 | Communications in Numerical Methods in Engineering2005，21，5： | 1 |
| 9 | Round-trip oscillation triboelectric nanogenerator with high output response and low wear to harvest random wind energy显示文摘Triboelectric nanogenerator(TENG)has made significant progress in wind energy harvesting.As the most advantageous rotary TENG among wind energy harvesters,the severe material wear and the output that fluctuates with wind speed seriously hinder the application of TENG wind energy harvesters.In this study,we propose a round-trip oscillation triboelectric nanogenerator(RTO-TENG)consisting of a crank transmission mechanism and a power generation unit.The RTO-TENG utilizes a simple crank transmission mechanism combined with a zigzag-laminated triboelectric nanogenerator(Z-TENG)to achieve high-performance constant output and low material wear.The crank transmission mechanism can realize the transformation from circular motion to arc reciprocating motion,converting the random wind energy into bi-directional kinetic energy,driving the vertical contact and separation of the Z-TENG.Due to the low transmission ratio(1:1)of the crank transmission mechanism and the consistent frequency of the Z-TENG contact–separation with that of the pendulum,the RTO-TENG’s power generation unit(10 Z-TENGs)is insensitive to changes in wind speed,resulting in a constant and stable output response at various speeds.After 480,000 cycles,the output of RTO-TENG decreased by only 0.9%compared to the initial value of 6μC,and the scanning electron microscopy(SEM)images of the polytetrafluoroethylene(PTFE)film showed no significant wear on the surface of the friction layer,demonstrating excellent output stability and abrasion resistance of the RTO-TENG wind energy collector’s material.The equipped energy management module,based on a gas discharge tube switch,can further enhance the output performance of the RTO-TENG.After optimizing its inductor parameter L to match the load capacitor,it can charge a 220μF load capacitor to 13.4 V in 40 s,resulting in a 298%improvement in charging speed compared to the voltage of 4.48 V without the management module.Therefore,the RTO-TENG can efficiently provide power to low-power small electronic devices for Internet of Things(IoTs),such as road traffic warning signs and thermo-hygrometers. | Xinyu Hu Junrui Feng Chuangjian Liang Heng Ning Chunjin Chen Jiayu Li Honggui Wen Huilu Yao Lingyu Wan Guanlin Liu | 2023 | Nano Research2023，16，8： | 1 |
| 10 | Experimen- tal and Numerical Studies on the Flame Instabilities in Porous Media 显示文摘 | SHI Junrui YU Chunmei LI Benwen | 2013 | Fuel2013，106，： | 1 |
| 11 | Numerical simulation and theoretical analysis of low-velocity filtration combustion of lean mixture 显示文摘 | Shi Junrui Xie Maozhao Liu Hong Li Gang ZhouLei | 2008 | International Journal of Heat and Mass Transfer2008，51，： | 1 |
| 12 | Prediction of the horizontal stress of the tight sand- stone formation in eastern Sulige of China显示文摘 | Fan Xiangyu Gong Ming Zhang Qiangui Wang Junrui Bai Li Chen Yingjie | 2014 | Journal of Petro- leum Science and Engineering2014，113，： | 1 |
| 13 | Coupled Seepage and Stress Fields in Roller Compacted Concrete Dam显示文摘 | Chai Junrui Li Kanghong Wu Yanqing | 2004 | Communications in Numerical Methods in Engineering2004，21，1： | 1 |
| 14 | Multi-level fracture network model and FE solution for ground water flow in rock mass显示文摘 | CHAI Junrui LI Shouyi LI Shouyi | 2005 | Journal of Hydraulic Research2005，43，2： | 1 |
| 15 | Prediction of the horizontal stress of the tight sandstone formation in eastern Sulige of China显示文摘 | Fan Xiangyu Gong Ming Zhang Qiangui Wang Junrui Bai Li Chen Yingjie | 2014 | Journal of Petroleum Science and Engineering2014，，113： | 1 |
| 16 | 3-75 Radiosensitizing Effects of miR-185 on Melanoma Cells显示文摘Melanoma is an aggressive malignancy with high metastasis and low survival rate, of which the incidence rate keeps increasing year by year worldwide while the therapeutic options are still limited up to now[1;2]. Melanoma is considered to be a relatively radioresistant tumor, and radiotherapy has an important role in its treatment, especially in patients with central nervous system metastases[3], so enhancement of cellular radiosensitivity by radiosensitizer is an efficient strategy to improve the outcome of radiotherapy. | He Jinpeng Tian Ning Yang Yanli Jin Liangliang Feng Xiu Hua Junrui Lin Sulan Wang Bing Li He Wang Jufang | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 17 | The Selection of Industry Given Preference in Development of Each Province: A Comparative Empirical Study Based on the Power of Industry Competition显示文摘 | Chengxiao Jin Junrui Li | 2005 | China-USA Business Review2005，4，11： | 0 |
| 18 | Ni_xWO_(2.72) nanorods as an efficient electrocatalyst for oxygen evolution reaction显示文摘Ni_xWO_(2.72) nanorods(NRs) are synthesized by a one-pot reaction of Ni(acac)_2 and WCl_4. In the rod structure, Ni(Ⅱ) intercalates in the defective perovskite-type WO_(2.72) and is stabilized. The Ni_xWO_(2.72) NRs show the x-dependent electrocatalysis for the oxygen evolution reaction(OER) in 0.1 M KOH with Ni_(0.78)WO_(2.72) being the most efficient, even outperforming the commercial Ir-catalyst. The synthesis is not limited to Ni_xWO_(2.72) but can be extended to M_xWO_(2.72)(M = Co, Fe) as well,providing a new class of oxide-based catalysts for efficient OER and other energy conversion reactions. | Zheng Xi Adriana Mendoza-Garcia Huiyuan Zhu MiaoFang Chi Dong Su Daniel P.Erdosy Junrui Li Shouheng Sun | 2017 | Green Energy & Environment2017，2，2： | 0 |
| 19 | Encapsulation of docosahexaenoic acid (DHA) using self-assembling food-derived proteins for efficient biological functions显示文摘Docosahexaenoic acid(DHA;22n-6)possesses multiple biological functions, including antioxidant activity and ameliorating hypertriglyceridemia. However, the application of DHA has been limited due to poor aqueous solubility and susceptible to oxidation. Here, ovalbumin(O), myosin(M), 7S soy globulin(S), and β-lactoglobulin(β), hydrolyzed by chymotrypsin, self-assembled into micelles, respectively. Adding incremental DHA to micelles caused endogenous fluorescence quenching of O, M, S, and β micelles, implying successful incorporation of DHA into hydrophobic cores of micelles(O(DHA), M(DHA), S(DHA), and β(DHA)). The results showed that micelles provided spatial stability and improved solubility, and stability against thermal and ultraviolet(UV)light for DHA. The uptake of DHA from M(DHA), β(DHA), O(DHA), and S(DHA)was 3.27-, 3.91-, 2.7-, and 3.95-fold higher, respectively, than that of DHA by Caco-2 cells. Encapsulation in micelles increased DHA aqueous solubility and uptake, which enhanced cellular endogenous antioxidant defense. Meanwhile, increased uptake of DHA was verified by HepG2 cells, and O, M, S, and β micelles were proven to increase DHA uptake to reduce lipid deposition. Our findings strongly support the possibility that O, M, S, and β micelles can be regarded as a carrier for loading DHA. | Yumeng Liu Kaixin Cao Tong Li Delun Mu Naiqi Zhang Ying Wang Rina Wu Junrui Wu | 2023 | Food Science and Human Wellness2023，12，5： | 0 |
| 20 | Effect of normal and strict anaerobic fermentation on physicochemical quality and metabolomics of yogurt显示文摘Generally,yogurts on the market are usually anaerobic fermentation,but oxygen can be still dissolved in the production process,which is actually not strict anaerobic.This study explored the multiple quality indicators and the metabolomic analysis of yogurts fermented by Lactobacillus bulgaricus and Streptococcus thermophilus using two fermentation methods,namely,strict anaerobic and normal fermentation.The changes in flavor substances in yogurts,including 17 free amino acids,17 fatty acids,and 7 response value,were detected using principal component and multi factor analyses.Based on the results of the comparisons between basic physical and chemical indicators,strict anaerobic fermentation increased the growth and acidification of the two bacteria,the response value of sourness,umami and richness.Strict anaerobic fermentation increased the free amino acid(Fold change=1.53)and short chain fatty acid levels(Fold change=1.73),and reduced the polyunsaturated fatty acid(Fold change=0.51)levels.Furthermore,metabolomic analysis based on UPLC-Triple TOF-MS/MS showed that 92 differential metabolites were screened;45 differential metabolites were increased and 47 were decreased.The results revealed that strict anaerobic fermentation was beneficial to metabolic changes and nutritional indicators of yogurt,which may be as indicators of valuable reference to improve dairy fermentation process. | Ruixue Ding Mohan Li Yiting Zou Yiran Wang Chunyue Yan Haibing Zhang Rina Wu Junrui Wu | 2022 | Food Bioscience2022，46，2： | 0 |
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