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3篇 您的检索式:作者名="Chenye Sun"
    题名 作者 年代 出处 被引量
1The heterolo-gous expression in Arabidopsis of a chrysanthemum Cys2/His2 zincfinger protein gene confers salinity and drought tolerance显示文摘GAO H S SONG A P ZHU X R CHEN F D JIANG J F CHENY SUN Y SHAN H7 GU CS LI P L CHEN S M 2012Planta2012,235,:1
2Bioinformatic analysis and in vivo validation of angiogenesis related genes in inflammatory bowel disease显示文摘Angiogenesis plays a significant role in the occurrence and development of inflammatory bowel disease(IBD).The aim of this study is to explore potential angiogenesis related genes(ARGs)in IBD through bioinformatics analysis and in vivo experiments.Methods:GSE57945,GSE87466,and GSE36807 were obtained from the Gene Expression Omnibus database.GSE57945 was used as the training set,while GSE87466 and GSE36807 were used as the validation set.The key ARGs associated with IBD were identified using the least absolute shrinkage and selection operator(LASSO)and random forest methods.These identified ARGs were then utilized to construct a diagnostic model for IBD.The Single-Sample Genome Enrichment Analysis,Cibersort,and Xcell methods were used to evaluate the immune infiltration.Expression of amyloid beta precursor protein(APP)was verified in the IBD mouse model induced by dextran sulfate sodium using immunohistochemistry(IHC).Results:The receiver operating curve area of GSE57945 was 0.948.Two distinct clusters were identified using consensus clustering and non-negative matrix factorization clustering.Subsequent analyses revealed significant differences in immune levels and functional enrichment between the two clusters.The successful construction of the animal model for the IBD was evident by hematoxylin and eosin staining,while IHC results showed a high expression of APP in IBD and a low expression in normal tissues.Conclusion:Our findings provide new insights into the diagnosis of IBD by ARGs,and APP could be a potential novel biomarker for IBD and promising therapeutic targets.ZEPENG DONG CHENYE ZHAO SHIBO HU KUI YANG JUNHUI YU XUEJUN SUN JIANBAO ZHENG 2023BIOCELL2023,47,12:0
3A Poisoning Outbreak Caused by Anisodus tanguticus — Maqin County, Qinghai Province, China, July 2021显示文摘Summary What is already known about this topic?Anisodus tanguticus belongs to the Solanaceae family.The plant is toxic due to the tropane alkaloids it contains and can cause poisoning when it is ingested or used inappropriately.What is added by this report?A poisoning outbreak involved 10 patients,and one death was caused by Anisodus tanguticus.The etiological association of plant exposure and poisoning was confirmed with evidence from an epidemiological investigation,clinical manifestations,plant identification and a toxin analysis.Xuebin Guo Qian He Bangguo Qi Chenye Sun DongJin Lyu Hongshun Zhang 2022China CDC weekly2022,4,41:0
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