|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Temperature action and effect of concrete-filled steel tubular bridges:A review显示文摘Concrete-filled steel tube(CFST)has been widely applied in bridges due to its excellent structural and constructional performance.In CFST bridges,temperature action is not only an important but also a special load that must be considered in bridge design,construction and structural evaluation.This paper presents an overview on current researches of the temperature action and effect of CFST bridges.The historical and spatial characteristics as well as corresponding influencing factors of temperature distributions are summarized,and classifications of temperature actions are also reviewed.Results show that in-depth investigations of the contributions of temperature influencing factors can help to effectively reduce the adverse temperature effects on CFST bridges in the design stage.Due to the lack of long-term measurements and insufficient use of historical meteorological data,research on the representative value along with correlation analysis of CFST temperature actions and meteorological parameters have to be further carried out.In the meanwhile,a decomposition method of temperature distribution is proposed based on structural effects of CFST bridges in this paper.The decomposed temperature actions can be used for more accurate effect calculation than traditional temperature action classification method,especially for CFST truss bridges.At last,specific temperature action patterns still need to be investigated in some of the special problems,such as longitudinal temperature differences along the CFST arch rib and thermal debonding in the CFST interface.Further investigations are required on the accurate simulation of temperature distribution of CFST bridges considering the shading effects of components and terrain. | Jiang Liu Yongjian Liu Chenyu Zhang Qiuhong Zhao Yi Lyu Lei Jiang | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，2： | 15 |
| 2 | Three-dimensional bioprinting of multicell-laden scaffolds containing bone morphogenic protein-4 for promoting M2 macrophage polarization and accelerating bone defect repair in diabetes mellitus显示文摘Critical-sized bone defect repair in patients with diabetes mellitus remains a challenge in clinical treatment because of dysfunction of macrophage polarization and the inflammatory microenvironment in the bone defect region.Three-dimensional(3D)bioprinted scaffolds loaded with live cells and bioactive factors can improve cell viability and the inflammatory microenvironment and further accelerating bone repair.Here,we used modified bioinks comprising gelatin,gelatin methacryloyl(GelMA),and 4-arm poly(ethylene glycol)acrylate(PEG)to fabricate 3D bioprinted scaffolds containing BMSCs,RAW264.7 macrophages,and BMP-4-loaded mesoporous silica nanoparticles(MSNs).Addition of MSNs effectively improved the mechanical strength of GelMA/gelatin/PEG scaffolds.Moreover,MSNs sustainably released BMP-4 for long-term effectiveness.In 3D bioprinted scaffolds,BMP-4 promoted the polarization of RAW264.7 to M2 macrophages,which secrete anti-inflammatory factors and thereby reduce the levels of pro-inflammatory factors.BMP-4 released from MSNs and BMP-2 secreted from M2 macrophages collectively stimulated the osteogenic differentiation of BMSCs in the 3D bioprinted scaffolds.Furthermore,in calvarial critical-size defect models of diabetic rats,3D bioprinted scaffolds loaded with MSNs/BMP-4 induced M2 macrophage polarization and improved the inflammatory microenvironment.And 3D bioprinted scaffolds with MSNs/BMP-4,BMSCs,and RAW264.7 cells significantly accelerated bone repair.In conclusion,our results indicated that implanting 3D bioprinted scaffolds containing MSNs/BMP-4,BMSCs,and RAW264.7 cells in bone defects may be an effective method for improving diabetic bone repair,owing to the direct effects of BMP-4 on promoting osteogenesis of BMSCs and regulating M2 type macrophage polarization to improve the inflammatory microenvironment and secrete BMP-2. | Xin Sun Zhenjiang Ma Xue Zhao Wenjie Jin Chenyu Zhang Jie Ma Lei Qiang Wenhao Wang Qian Deng Han Yang Jinzhong Zhao Qianqian Liang Xiaojun Zhou Tao Li Jinwu Wang | 2021 | Bioactive Materials2021，6，3： | 12 |
| 3 | On the Key Dynamical Processes Supporting the 21.7 Zhengzhou Record-breaking Hourly Rainfall in China显示文摘An extremely heavy rainfall event occurred in Zhengzhou,China,on 20 July 2021 and produced an hourly rainfall rate of 201.9 mm,which broke the station record for China's Mainland.Based on radar observations and a convection-permitting simulation using the WRF-ARW model,this paper investigates the multiscale processes,especially those at the mesoscale,that support the extreme observed hourly rainfall.Results show that the extreme rainfall occurred in an environment characteristic of warm-sector heavy rainfall,with abundant warm moist air transported from the ocean by an abnormally northward-displaced western Pacific subtropical high and Typhoon In-Fa(2021).However,rather than through back building and echo training of convective cells often found in warm-sector heavy rainfall events,this extreme hourly rainfall event was caused by a single,quasi-stationary storm in Zhengzhou.Scale separation analysis reveals that the extreme-rainproducing storm was supported and maintained by the dynamic lifting of low-level converging flows from the north,south,and east of the storm.The low-level northerly flow originated from a mesoscale barrier jet on the eastern slope of the Taihang Mountain due to terrain blocking of large-scale easterly flows,which reached an overall balance with the southerly winds in association with a low-level meso-β-scale vortex located to the west of Zhengzhou.The large-scale easterly inflows that fed the deep convection via transport of thermodynamically unstable air into the storm prevented the eastward propagation of the weak,shallow cold pool.As a result,the convective storm was nearly stationary over Zhengzhou,resulting in record-breaking hourly precipitation. | Peng WEI Xin XU Ming XUE Chenyue ZHANG Yuan WANG Kun ZHAO Ang ZHOU Shushi ZHANG Kefeng ZHU | 2023 | Advances in Atmospheric Sciences2023，40，3： | 9 |
| 4 | Non-destructive detection of pigments in oil painting by using terahertz tomography显示文摘Dear Editors,Terahertz technology has been applied in many fields[1–3].The protection and restoration of historical relics and cultural heritage,which is a new application area of terahertz technology,have been attracting much attention recently[4,5]because of its social significance and market prospects.The most important premise is to obtain information of the cultural relics without damaging them again.Therefore the appropriate non-destructively testing methods are | ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHAO YuanMeng LI ChenYu GU An SHI NingChang ZHAO Kun ZHAN HongLei ZHANG CunLin | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 8 |
| 5 | Secreted miR-34a in astrocytic shedding vesicles enhanced the vulnerability of dopaminergic neurons to neurotoxins by targeting Bcl-2显示文摘MicroRNAs (miRNAs ) 是在 posttranscriptional 水平调整目标基因表示的 noncoding RNA 的一个类,导致进一步生物的函数。我们证明了 microvesicles (MV ) 能作为细胞间的通讯的一个新奇方法交付 miRNAs 进目标房间。在中央神经系统, glial 房间释放 MV,这被报导,它处于正常状况调制 neuronal 功能。阐明在疾病的 glial MV 的潜在的角色,我们在压力状况上评估了分泌 astrocytic MV 的效果。我们的结果证明在 Lipopolysaccharide (LPS ) 刺激以后,星形细胞释放了流提高了 dopaminergic 神经原的危险到神经毒素的泡(SV ) 。进一步的调查证明在 SV 的那增加的 astrocytic miR-34a 经由在 dopaminergic 神经原指向 anti-apoptotic 蛋白质 Bcl-2 涉及这进步。我们也发现在 LPS 刺激以后的 astrocytic miR-34a 的抑制能在神经毒素应力下面推迟 dopaminergic 神经原损失。这些数据揭示了在疾病位于星形细胞神经原相互作用下面的新奇机制。 | Susu Mao | 2015 | Protein & Cell2015，6，7： | 7 |
| 6 | Identification of Ebola virus microRNAs and their putative pathological function显示文摘Ebola virus(EBOV),a member of the filovirus family,is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates.Recently,more than 1000 people have been killed by the Ebola virus disease in Africa,yet no specific treatment or diagnostic tests for EBOV are available.In this study,we identified two putative viral microRNA precursors(pre-miRNAs)and three putative mature microRNAs(miRNAs)derived from the EBOV genome.The production of the EBOV miRNAs was further validated in HEK293T cells transfected with a pcDNA6.2-GW/EmGFP-EBOV-pre-miRNA plasmid,indicating that EBOV miRNAs can be produced through the cellular miRNA processing machinery.We also predicted the potential target genes of these EBOV miRNAs and their possible biological functions.Overall,this study reports for the first time that EBOV may produce miRNAs,which could serve as non-invasive biomarkers for the diagnosis and prognosis of EBOV infection and as therapeutic targets for Ebola viral infection treatment. | LIANG HongWei ZHOU Zhen ZHANG SuYang ZEN Ke CHEN Xi ZHANG ChenYu | 2014 | Science China(Life Sciences)2014，57，10： | 5 |
| 7 | Global and regional trends in incidence and mortality of female breast cancer and associated factors at national level in 2000 to 2019显示文摘Background: Female breast cancer (FBC) has become the most prevalent malignancy worldwide. We aimed to evaluate the global and regional burden in epidemiological trends and factors associated with the incidence and mortality of FBC.Methods: FBC incidence and mortality in 60 selected countries by cancer registry data integrity in 2020 were estimated from the GLOBOCAN database, and their association with the human development index (HDI) was further evaluated. Trends of age-standardized rates of incidence and mortality in 60 countries from 2000 through 2019 were evaluated by joinpoint regression analysis using data of Global Burden of Disease 2019. The association between potential behavioral, metabolic, and socioeconomic risk factor exposure at the nation level retrieved from the World Bank and Global Health Observatory and the incidence and mortality of FBC were evaluated by multivariate linear regression.Results: FBC incidence and mortality varied greatly in the 60 included countries. Higher incidence and mortality rates were typically observed in countries with higher HDIs and vice versa. During 2000 to 2019, significantly increasing trends in incidence and mortality were observed in 26 (average annual percent changes [AAPCs], 0.35-2.96) and nine countries (AAPC, 0.30-1.65), respectively, while significantly decreasing trends in both incidence and mortality were observed in 22 countries, most of which were high-HDI countries. Among the population aged ≥40 years, there were 26 and 11 countries showing significantly increased trends in incidence and mortality, respectively. Ecological analysis showed that countries with higher prevalence rates of high cholesterol and higher health expenditures were more likely to have higher FBC incidence, and countries with higher rates of obesity and poorer universal health coverage were more likely to have higher FBC mortality.Conclusions: Despite decreased or stabilized FBC incidence and mortality rates were observed in some countries with high HDI over the past decades, disease burden became even severer in developing countries, especially for the population aged ≥40 years. Effective targeted preventive programs are strongly encouraged to reduce the FBC disease burden worldwide. | Chenyu Luo Na Li Bin Lu Jie Cai Ming Lu Yuhan Zhang Hongda Chen Min Dai | 2022 | Chinese Medical Journal2022，，1： | 5 |
| 8 | Effects of Jiazhu decoction in combination with cyclophosphamide on breast cancer in mice显示文摘OBJECTIVE: To investigate the therapeutic effects of Jiazhu decoction (JZD) in combination with cyclophosphamide (CTX) on the growth of breast cancer in mice and to explore the possible molecular mechanisms of action. METHODS: BALB/c mice were randomly divided into four groups of 10 (untreated model group, JZD group, CTX group, and JZD + CTX group) and subcutaneously injected with 4T1 mouse breast cancer cells. Tumors were allowed to establish for ~7 d before initiation of treatment with CTX (100 mg/kg every week by intraperitoneal injection) and/or JZD (0.015 mL of 1.65 g/mL crude drug, administered daily by gavage). The model group received equivalent volumes of vehicle on the same schedules. Tumor volumes were measured every 3 d. Mice were sacrificed after 3 weeks of treatment, and tumors were excised and subjected to RT-qPCR and western blot analysis to evaluate expression of the Wnt/β-catenin signaling pathway components β-catenin, c-Myc, and cyclin D1 at the mRNA and protein levels. RESULTS: The mean tumor volume was smaller and the growth rate was slower in the CTX and JZD + CTX groups compared with the model group (P < 0.05), and in the JZD + CTX group compared with the CTX and JZD groups (P < 0.05). Tumor growth was inhibited by 35.4% and 48.1% by CTX and JZD + CTX treatment, respectively (P < 0.001). The expression of β-catenin, c-Myc, and cyclin D1 mRNA and protein in tumors was significantly lower in mice treated with JZD or JZD + CTX compared with the untreated mice (P < 0.05), and was significantly lower in mice treated with JZD + CTX compared with either JZD or CTX alone (P < 0.05). CONCLUSION: JZD inhibited the growth of mouse breast cancer cells in vivo, possibly by reducing the expression of β-catenin, c-Myc, and cyclin D1. Combination therapy with JZD plus CTX had a more potent inhibitory effect on breast cancer growth compared with either agent alone. | Guan Huiting Xie Su Liu Shangyi Xie Qing Hou Shengkai Liu Huarong Zhang Yunjie Hu Yaqing Zhang Chenyu | 2019 | Journal of Traditional Chinese Medicine2019，39，5： | 4 |
| 9 | Understanding the forces acting in self-assembly and the implications for constructing three-dimensional (3D) supercrystals显示文摘进称为 supercrystals 或上层建筑的订的结构的 nanocrystals 的集会由于象相关那样的众多的有用应用成为了枢轴的边疆在宏观的晶体的原子的安排并且调节集体性质遇见各种各样的应用的要求。在这篇文章,在 nanocrystals 的三维的超点阵的准备的最近的进步被构画出,与在有序的汇编以外的驱动力和进化线路上的一个特别重音。首先,带或内部并且外部地管理三维的 supercrystals 的形成的斥力系统地在三维的组织工会关于他们的起源和功能被识别并且讨论。然后,基于象微滴蒸发和一个液体 / 液体接口那样的生长情形自己组装的 nanocrystal 的通常应用的工具的摘要的介绍与特定的盒子被介绍并且详细说明了分析。最后,为这块地的存在挑战和前景简短被加亮。 | Chenyu wang1 Carrie Siu Jun Zhang Jiye Fang | 2015 | Nano Research2015，8，8： | 3 |
| 10 | Distinct functions of polycomb group proteins in regulating Ci transcription in developing Drosophila显示文摘 | Xiangdong Lv Hao Chen Shuo Zhang Zhao Zhang Chenyu Pan Yuanxin Xia Jialin Fan Wenqing Wu Yi Lu Lei Zhang Hailong Wu Yun Zhao | 2018 | Journal of Molecular Cell Biology2018，10，5： | 3 |
| 11 | PtNi-W/C with Atomically Dispersed Tungsten Sites Toward Boosted ORR in Proton Exchange Membrane Fuel Cell Devices显示文摘The performance of proton exchange membrane fuel cells is heavily dependent on the microstructure of electrode catalyst especially at low catalyst loadings.This work shows a hybrid electrocatalyst consisting of PtNi-W alloy nanocrystals loaded on carbon surface with atomically dispersed W sites by a two-step straightforward method.Single-atomic W can be found on the carbon surface,which can form protonic acid sites and establish an extended proton transport network at the catalyst surface.When implemented in membrane electrode assembly as cathode at ultra-low loading of 0.05 mgPt cm^(−2),the peak power density of the cell is enhanced by 64.4%compared to that with the commercial Pt/C catalyst.The theoretical calculation suggests that the single-atomic W possesses a favorable energetics toward the formation of*OOH whereby the intermediates can be efficiently converted and further reduced to water,revealing a interfacial cascade catalysis facilitated by the single-atomic W.This work highlights a novel functional hybrid electrocatalyst design from the atomic level that enables to solve the bottle-neck issues at device level. | Huawei Wang Jialong Gao Changli Chen Wei Zhao Zihou Zhang Dong Li Ying Chen Chenyue Wang Cheng Zhu Xiaoxing Ke Jiajing Pei Juncai Dong Qi Chen Haibo Jin Maorong Chai Yujing Li | 2023 | Nano-Micro Letters2023，15，9： | 3 |
| 12 | Integration of Multiple Heterointerfaces in a Hierarchical 0D@2D@1D Structure for Lightweight,Flexible,and Hydrophobic Multifunctional Electromagnetic Protective Fabrics显示文摘The development of wearable multifunctional electromagnetic protective fabrics with multifunctional,low cost,and high efficiency remains a challenge.Here,inspired by the unique flower branch shape of“Thunberg’s meadowsweet”in nature,a nanofibrous composite membrane with hierarchical structure was constructed.Integrating sophisticated 0D@2D@1D hierarchical structures with multiple heterointerfaces can fully unleash the multifunctional application potential of composite membrane.The targeted induction method was used to precisely regulate the formation site and morphology of the metal–organic framework precursor,and intelligently integrate multiple heterostructures to enhance dielectric polarization,which improves the impedance matching and loss mechanisms of the electromagnetic wave absorbing materials.Due to the synergistic enhancement of electrospinning-derived carbon nanofiber“stems”,MOF-derived carbon nanosheet“petals”and transition metal selenide nano-particle“stamens”,the CoxSey/NiSe@CNSs@CNFs(CNCC)composite membrane obtains a minimum reflection loss value(RL_(min))of-68.40 dB at 2.6 mm and a maximum effective absorption bandwidth(EAB)of 8.88 GHz at a thin thickness of 2.0 mm with a filling amount of only 5 wt%.In addition,the multi-component and hierarchical heterostructure endow the fibrous membrane with excellent flexibility,water resistance,thermal management,and other multifunctional properties.This work provides unique perspectives for the precise design and rational application of multifunctional fabrics. | Shuo Zhang Xuehua Liu Chenyu Jia Zhengshuo Sun Haowen Jiang Zirui Jia Guanglei Wu | 2023 | Nano-Micro Letters2023，15，11： | 3 |
| 13 | Synergetic Improvement of Interlaminar Fracture Toughness in Carbon Fiber/Epoxy Composites Interleaved with PES/PEK‑C Hybrid Nanofiber Veils显示文摘In this study,two types of soluble thermoplastic resins were added to epoxy resin at a fixed weight ratio to prepare a three-phase cast body.The cast was then manufactured into hybrid nanofiber as interleaves for interlaminar toughening of carbon fiber/epoxy resin(CF/EP)composites using a co-solvent method.The results revealed that when the hybrid components reached 15 wt%,Polyethersulfone(PES)and polyaryletherketone cardo(PEK-C)exhibited the best synergistic toughening effect,and the fracture toughness increased by 99.8%and 39.8%,respectively,compared with the reference or the same proportion of the single PES toughened sample.We used PES/PEK-C hybrid nanofibers with an areal density of 19.2 g per square meter(gsm)as composite toughening layers.Apart from the lack of significant influence of PES nanofiber on CF/EP composites,the interlaminar fracture toughness of mode I and mode II layers increased by 88.3%and 46.9%,respectively,compared to the reference sample.Scanning Electron Microscopy of the fracture surface and cross-section micromorphology of the laminate displayed that the thermoplastic microspheres of different sizes contribute differently to crack resistance:PEK-C consumes more energy due to the debonding and extraction of microspheres and resin,whereas the presence of the PES phase can induce more plastic deformation and crack deflection. | Jinli Zhou Chenyu Zhang Chao Cheng Ming Wang Zhihui Yang Yanfei Yang Hongying Yang Muhuo Yu | 2022 | Advanced Fiber Materials2022，4，5： | 3 |
| 14 | Analysis of TM/TE mode enhancement and droop reduction by a nanoporous n-AIGaN underlayer in a 290 nm UV-LED显示文摘A full structure 290 nm ultraviolet light emitting diode(UV-LED)with a nanoporous n-AlGaN underlayer was fabricated by top via hole formation followed by high-voltage electrochemical etching.The 20 to 120 nm nanopores were prepared in regular doped n-AlGaN by adjusting the etching voltage.The comparison between the Raman spectrum and the photoluminescence wavelength shows that the biaxial stress in the nanoporous material is obviously relaxed.The photoluminescence enhancement was found to be highly dependent on the size of the pores.It not only improves the extraction efficiency of top-emitting transverse-electric(TE)-mode photons but also greatly improves the efficiency of side emitting tran sverse-magnetic(TM)-mode photons.This leads to the polarization change of the side-emitting light from-0.08 to-0.242.The intensity of the electroluminescence was increased by 36.5%at 100 mA,and the efficiency droop at high current was found to decrease from 61%to 31%. | YUFENG LI CHENYU WANG YE ZHANG PENG HU SHENGNAN ZHANG MENGQI DU XILIN SU QIANG LI FENG YUN | 2020 | Photonics Research2020，8，6： | 2 |
| 15 | Current knowledge of Krüppel-like factor 5 and vascular remodeling: providing insights for therapeutic strategies显示文摘Vascular remodeling is a pathological basis of various disorders. Therefore, it is necessary to understand the occurrence, prevention, and treatment of vascular remodeling. Krüppel-like factor 5 (KLF5) has been identified as a significant factor in cardiovascular diseases during the last two decades. This review provides a mechanism network of function and regulation of KLF5 in vascular remodeling based on newly published data and gives a summary of its potential therapeutic applications. KLF5 modulates numerous biological processes, which play essential parts in the development of vascular remodeling, such as cell proliferation, phenotype switch, extracellular matrix deposition, inflammation, and angiogenesis by altering downstream genes and signaling pathways. Considering its essential functions, KLF5 could be developed as a potent therapeutic target in vascular disorders. | Ziyan Xie Junye Chen Chenyu Wang Jiahao Zhang Yanxiang Wu Xiaowei Yan | 2021 | Journal of Molecular Cell Biology2021，13，2： | 2 |
| 16 | MicroRNA-29a modulates axon branching by targeting doublecortin in primary neurons显示文摘MicroRNAs (miRNAs ) 内长地被表示调整蛋白质表示的小、非编码的抄本。实质的证据建议 miRNAs 在中央神经系统被充实,在他们被假设在神经开发期间起枢轴的作用的地方。在现在的学习,我们在在不同发展阶段和发现 miR-29a 的服的外皮和马头鱼尾的怪兽在出生后的阶段戏剧性地增加了的老鼠分析了 miRNAs 表示。另外,我们提供了 miR-29a 在 vitro 并且在 vivo 在成熟神经原被充实的充分证据。进一步的调查证明 glutamate 受体的激活在主要神经原导致了内长的 miR-29a 水平。而且,我们证明 miR-29a 直接调整了它的目标蛋白质 Doublecortin (DCX ) 表示,它进一步调制的轴突在主要文化分叉。一起,我们的结果建议 miR-29a 在鼠标的 neuronal 开发起一个重要作用大脑。 | Hanqin Li Susu Mao Haitao Wang Ke Zen Chenyu Zhang Liang Li | 2014 | Protein & Cell2014，5，2： | 2 |
| 17 | Final Closure Time of the Paleo-Asian Ocean: Implication from the Provenance Transformation from the Yangjiagou Formation to Lujiatun Formation in the Jiutai Area, NE China显示文摘The Jiutai area is tectonically situated at the eastern segment of the Central Asian Orogenic Belt(CAOB) and is close to the North China Craton(NCC) to the south, serving as an ideal place to investigations of the closure of the PaleoAsian Ocean(PAO). Sandstone samples collected from the Yangjiagou Formation and the Lujiatun Formation in this area have been studied in detail in terms of petrology, geochronology and geochemistry. The maximum depositional time of the Yangjiagou and Lujiatun formations has been constrained to early Middle Triassic(ca. 245 Ma) and middle Late Triassic(ca. 219 Ma), respectively. The Yangjiagou Formation, with a major provenance of dissected island arcs, is dominantly composed of Phanerozoic sediments from Northeastern China(NE China) massifs. The Lujiatun Formation, with major sediments from active continental margins, has a relatively larger proportion of Precambrian sediments, in which the ~1.85 Ga and ~2.5 Ga sediments are typical of the crystalline basements of the NCC and NE China massifs, which were uplifted and eroded during the closure of the PAO. Besides, both formations show the enrichment in LREEs and the depletion in HREEs, the common Eu negative anomalies, and trace element contents similar to that of the upper continental crust. Based on the provenance analysis of these two formations, the final closure time of the PAO in this area is constrained as from the early Middle Triassic(ca. 245 Ma) to the middle Late Triassic(ca. 219 Ma). | ZHANG Qian LIANG Chenyue LIU Yongjiang ZHENG Changqing LI Weimin | 2019 | Acta Geologica Sinica(English Edition)2019，93，5： | 2 |
| 18 | Hybrid Dirac semimetal-based photodetector with efficient low-energy photon harvesting显示文摘Despite the considerable effort,fast and highly sensitive photodetection is not widely available at the low-photon-energy range(~meV)of the electromagnetic spectrum,owing to the challenging light funneling into small active areas with efficient conversion into an electrical signal.Here,we provide an alternative strategy by efficiently integrating and manipulating at the nanoscale the optoelectronic properties of topological Dirac semimetal PtSe_(2)and its van der Waals heterostructures.Explicitly,we realize strong plasmonic antenna coupling to semimetal states near the skin-depth regime(λ/10^(4)),featuring colossal photoresponse by in-plane symmetry breaking.The observed spontaneous and polarization-sensitive photocurrent are correlated to strong coupling with the nonequilibrium states in PtSe_(2)Dirac semimetal,yielding efficient light absorption in the photon range below 1.24 meV with responsivity exceeding∼0.2 A/W and noise-equivalent power(NEP)less than~38 pW/Hz^(0.5),as well as superb ambient stability.Present results pave the way to efficient engineering of a topological semimetal for high-speed and low-energy photon harvesting in areas such as biomedical imaging,remote sensing or security applications. | Lin Wang Li Han Wanlong Guo Libo Zhang Chenyu Yao Zhiqingzi Chen Yulu Chen Cheng Guo Kaixuan Zhang Chia-Nung Kuo Chin Shan Lue Antonio Politano Huaizhong Xing Mengjie Jiang Xianbin Yu Xiaoshuang Chen Wei Lu | 2022 | Light(Science & Applications)2022，11，3： | 2 |
| 19 | Spectrin:Structure, function and disease显示文摘Spectrin is a large,cytoskeletal,and heterodimeric protein composed of modular structure of and subunits,it typically contains 106 contiguous amino acid sequence motifs called'spectrin repeats'.Spectrin is crucial for maintaining the stability and structure of the cell membrane and the shape of a cell.Moreover,it contributes to diverse cell functions such as cell adhesion,cell spreading,and the cell cycle.Mutations of spectrin lead to various human diseases such as hereditary hemolytic anemia,type 5 spinocerebellar ataxia,cancer,as well as others.This review focuses on recent advances in determining the structure and function of spectrin as well as its role in disease. | ZHANG Rui ZHANG ChenYu ZHAO Qi LI DongHai | 2013 | Science China(Life Sciences)2013，56，12： | 2 |
| 20 | Fsh-Pc-Sce complex mediates active transcription of Cubitus interruptus (Ci)显示文摘表明小径的刺猬(Hh ) 在胚胎的开发和成年织物动态平衡起重要作用。如此的生物功能被抄写因素肘脉 interruptus (Ci ) 调停。然而,受动器 Ci 本身的 transcriptional 规定糟糕被调查。通过一幅基于 RNAi 的基因屏幕,我们识别了那女性无菌(1 ) homeotic (Fsh ) ,抄写激活剂,直接激活 Ci 抄写。生物化学试金在 Fsh 之中表明了物理相互作用,性梳子额外(Sce ) ,并且 Polycomb (Pc ) 。功能的试金进一步证明 Pc 和 Sce 为 Ci 被要求表示,没被 Engrailed 的 derepression 多半调停,) , Ci 的一个抑压者,在 Pc 或 Sce 异种房间。最后,我们提供证明 Pc/Sce 在 Ci 地点便于 Fsh 的绑定并且在 Fsh 和 Pc 之间的物理相互作用为调停 Fsh 的 Ci 抄写是必要的证据。一起拿,我们不仅揭开那 Ci 被复杂的 Fsh-Pc-Sce transcriptionally 调整而且在 transcriptional 为在 Fsh 和 PcG 蛋白质之间的协作提供证据规定。 | Xiangdong Lv Hao Chen Shuo Zhang Zhao Zhang Chenyu Pan Yuanxin Xia Jialin Fan Wenqing Wu Yi Lu Lei Zhang Hailong Wu Yun Zhao | 2018 | Journal of Molecular Cell Biology2018，10，5： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员