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93篇 您的检索式:作者名="Chiu A P"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Immunological study of hal domain of he- magglutinin of influenza hSnl virus 显示文摘Chiu F F Venkatesan N Wu C R Chou A H Chen H W Lian S P Liu SJ Huang C C Lian W C Chong P Leng C H 2009Biochemical Biophys ResCommun2009,383,1:1
3Microbial reduction of perchlorate with zero-valent iron显示文摘Son A Lee J Chiu P C 2006Water Research2006,40,10:1
4Position statement from the aneuploidy screening committee on behalf of the board of the international society for prenatal diagnosis显示文摘Benn P Borell A Chiu R 2013Prenat Diagn2013,33,7:1
5The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing显示文摘Briley G P Hissong M A Chiu M L 1997Mol Biol Cell1997,8,8:1
6Position statement from theAneuploidy Screening Committee on behalf of the Board of theInternational Society for Prenatal Diagnosis显示文摘Benn P Borell A Chiu R 2013Prenat Diagn2013,33,:1
7显示文摘Johnson M F L Voss A P Bauer S H Chiu N S 1986J Catal1986,98,:1
8A method for measuring PVT relationships of thermoplastics using an injection molding machine 显示文摘CHIU C P LIU K A WEI J H 1995Polymer Engineering & Science1995,35,19:1
9显示文摘Chen N C Chang P H Chiu A P 2004Appl Phys Lett2004,84,:1
10Starch and protein quality requirement of Japanese noodles (ramen) 显示文摘Crosbic G B Ross A S Moro T Chiu P C 1999Cereal Chemistry1999,76,:1
11Using Semijoins to Solve Relational Queries显示文摘Bemtstein P A Chiu D W 1981Journal of the ACM1981,28,1:1
12Dissipation of Fragrance Materials in Sludge-Amended Soils 显示文摘Difranceseo A Chiu P Standley 2004Environ Sci Technol2004,38,:1
13Characteristics of lower extremity work during the impact phase of jumping and weightlifting显示文摘MOOLYK A N CAREY J P CHIU L Z F 2013J Strength Conditioning Res2013,27,12:1
14Stage specificity of novel growth factor expression during development of proliferative vitreoretinopathy显示文摘Cui JZ Chiu A1Maberley D Ma P Samad A Matsubara JA 2007Eye(Lond)2007,21,2:1
15Chromosome in situ hybridisation,Ki-67,and telomerase immunocyto-chemistry in liquid based cervical cytology显示文摘Cheung A N Y Chiu P M Tsun K 2004J Clin Pathol2004,57,7:1
16Effect of coagulation on the size of MF and UF membrane foulants 显示文摘Howe K J Marwah A Chiu K P 2006Environmental Science & Technology2006,40,24:1
17Switchable solvents consisting of amidine/alcohol or guanidine/alcohol mixtures 显示文摘Phan L Chiu D Heldebrant D J Huttenhower H John E Li X Pollet P Wang R Eckert C A Liotta C L Jessop P G 2008Industrial & Engineering Chemistry Research2008,47,:1
18Effect of cadmium on cell cycle progression in Chinese hamster ovary cells 显示文摘Yang P M Chiu S J Lin K A 2004Chemico-biological interactions2004,149,23:1
19A method for measuring PVT relationships of thermoplastics using an injection molding machine显示文摘Chiu C P Liu K A Wei J H 1995Polymer Engineering and Science1995,35,19:1
20Feeding aquaculture in an era of finite resources显示文摘Naylor R L Hardy R W Bureau D P Chiu A Elliott M Farrell A P Forster I Gatlin D M Goldburg R J Hua K Nichols P D 2009PNAS2009,106,15:1
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