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| 1 | Acoustic radiation force impulse elastography for hepatocellular carcinoma-associated radiofrequency ablation显示文摘AIM:To evaluate the potential usefulness of acoustic radiation force impulse (ARFI) images for evaluation of hepatocellular carcinomas (HCC)-associated radiofrequency ablation. METHODS:From January 2010 to June 2010,a total of 38 patients with HCC including recurred HCCs after RFA underwent ARFI elastography. The brightness of tumor was checked and the shear wave velocity was measure-d for the-quantification of stiffne-ss. According to theb-rightne-ss,the-tumors we-re-classifie-d as b-righte-r,samecolor and darker compared with adjacent parenchyma. Using the same methods,8 patients with recurred HCCs after RFA state were evaluated about the brightness compared with adjacent RFA ablation area. RESULTS:In the 38 patients with HCCs,20 (52.6%)were brighter than surrounding cirrhotic parenchyma. Another 13 (34.2%) were darker. The others (5 cases,13.2%) were seen as the same color as the adjacent liver parenchyma. Post-RFA lesions were darker than previous tumor and surrounding parenchyma in all 38 cases. However,recurred HCCs were brighter than the treated site in all 8 cases. CONCLUSION:Using ARFI technique is helpful for differential diagnosis in order to detect recurred HCCs more easily in patients with confusing status. | Hee-Jin Kwon Myong-Jin Kang Jin-Han Cho Jong-Young Oh Kyung-Jin Nam Sang-Yeong Han Sung Wook Lee | 2011 | World Journal of Gastroenterology2011，17，14： | 21 |
| 2 | Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient显示文摘Sorafenib,a multitargeted tyrosine kinase inhibitor,has been shown to improve survival in patients with advanced hepatocellular carcinoma(HCC).As the clinical use of sorafenib increases,many adverse effects have been reported,such as hand-foot skin reaction,diarrhea,anorexia,asthenia,alopecia,weight loss,hypertension and arterial thromboembolism.However,there are no prior reports of splenic infarction as an adverse effect of sorafenib.Here,a case of splenic infarction in a patient with HCC who was treated with sorafenib is reported. The patient had no other predisposing factors to explain the splenic infarction except for the administration of sorafenib.The splenic infarction improved after sorafenib was discontinued;however,the HCC progressed. | Sang Ock Kim Sang Young Han Yang Hyun Baek Sung Wook Lee Ji Sun Han Byung Geun Kim Jin Han Cho Kyung Jin Nam | 2011 | World Journal of Gastroenterology2011，17，2： | 7 |
| 3 | Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma显示文摘AIM:To investigate the efficacy of hepatic arterial infusion chemotherapy(HAIC) using floxuridine(FUDR) in patients with advanced hepatocellular carcinoma(HCC) confined to the liver.METHODS:Thirty-four patients who had advanced HCC with unresectability or unsuccessful previous therapy in the absence of extrahepatic metastasis were treated with intra-arterial FUDR chemotherapy at ourhospital between March 2005 and May 2008.Among the 34 patients,9 patients were classified as Child class C,and 18 patients had portal vein tumor thrombus(PVTT).One course of chemotherapy consisted of continuous infusion of FUDR(0.3 mg/kg during day 1-14) and dexamethasone(10 mg on day 1,4,7 and 11),and this treatment was repeated every 28 d.RESULTS:Two patients(5.9%) displayed a complete response,and 12 patients(35.3%) had a partial response.The tumor control rate was 61.8%.The median overall survival times were 15.3 mo,12.4 mo and 4.3 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0392).The progression-free survival was 12.9 mo,7.7 mo and 2.6 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0443).The cumulative survival differed significantly according to the Child-Pugh classification and the presence of PVTT.In addition to hepatic reserve capacity and PVTT,the extent of HCC was an independent factor in determining a poor prognosis.The most common adverse reactions to HAIC were mucositis,diarrhea and peptic ulcer disease,but most of these complications were improved by medical treatment and/or a delay of HAIC.CONCLUSION:The present study demonstrates that intra-arterial FUDR chemotherapy is a safe and effective treatment for advanced HCC that is recalcitrant to other therapeutic modalities,even in patients with advanced cirrhosis. | Yang Hyun Baek Kyoung Tae Kim Sung Wook Lee Jin Sook Jeong Byeong Ho Park Kyung Jin Nam Jin Han Cho Young Hoon Kim Young Hoon Roh Hyung Sik Lee Young Min Choi Sang Young Han | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 4 | 韩国中年男性血清25-羟维生素D水平与皋酮缺乏:一项横向研究显示文摘原先的研究证明,男性性腺机能减退与维生素D低水平有关。然而,有关韩国男性维生素D对睾酮水平影响的研究尚未见报道。本研究的目的在于探讨睾酮的水平是否与血清维生素D水平相关,以及是否存在季节性变化。本横向研究分析了652名40岁以上韩国男性的血清25.羟维生素D[25(OH)D]、总睾酮(TT)以及游离睾酮(FT)水平。这些男性都经过了全面的体检。受试者的平均年龄56.7±7.9岁,平均血清血25.羟维生素D、总睾酮以及游离睾酮水平分别为21.23±7.9ngml-1,4.70±1.6ngml-1和8.12±3.3pgml-1。在多元线性回归模型,25.羟维生素D与总睾酮水平(B=O.137,P〈O.001)以及游离睾酮水平(B=0.103,P=O.008)呈现正相关。在调整了年龄因素之后,25.羟维生素D与游离睾酮水平之间呈现相似的季节性变化或月变化。在调整了年龄、季节、体重指数、身体成分、慢性疾病、吸烟以及饮酒等因素之后,维生素D缺乏[25(OH)D〈20ngml-1]与总睾酮水平缺乏(〈2.30ngml-1)的风险增高(风险率[OR]:2.65;95%可信区间:1.21—5.78,P=0.014)以及游离睾酮水平缺乏(〈6.50Pgml-1)的风险增高(OR:1.44;95%可信区间:1.01-2.06,P=O.048)相关。综上所述,我们证明了韩国男性血清25.羟维生素D与睾酮水平之间的正相关,并呈现季节性波动。 | Young Jin Tak Jeong Gyu Lee Yun Jin Kim Nam Cheol Park Sang Soo Kim Sangyeoup Lee Byung Mann Cho Eun Hee Kong Dong Wook Jung Yu Hyeon Yi | 2015 | Asian Journal of Andrology2015，17，2： | 5 |
| 5 | Predictive value of glycosylated hemoglobin for mortality of patients with acute myocardial infarction undergoing percutaneous coronary intervention显示文摘 | Min Goo Lee Myung Ho Jeong Dong Han Kim Ki Hong Lee Keun Ho Park Doo Sun Sim Hyun Ju Yoon Nam Sik Yoon Kye Hun Kim Hyoung Wook Park Young Joon Hong Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2012 | International Journal of Cardiology2012，，1： | 1 |
| 6 | Impact of Baseline Plaque Components on Plaque Progression in Nonintervened Coronary Segments in Patients With Angina Pectoris on Rosuvastatin 10 mg/day显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Eun Hye Ma Jum Suk Ko Min Goo Lee Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2010 | The American Journal of Cardiology2010，，9： | 1 |
| 7 | Different clinical outcomes of acute kidney injury according to acute kidney injury network criteria in patients between ST elevation and non-ST elevation myocardial infarction显示文摘 | Seung Hwan Hwang Myung Ho Jeong Khurshid Ahmed Min Chul Kim Kyung Hoon Cho Min Goo Lee Jum Suk Ko Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Young keun Ahn Jeong Gwan Cho Jong Chun Park Jung C | 2011 | International Journal of Cardiology2011，，1： | 1 |
| 8 | Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | JACC: Cardiovascular Imaging2009，，3： | 1 |
| 9 | The prevalence and risk factors of vertebral fractures in Korea显示文摘 | Chan Soo Shin Min Joo Kim Sang Mi Shim Jin Taek Kim Sung Hoon Yu Bo Kyung Koo Hwa Young Cho Hyung Jin Choi Sun Wook Cho Sang Wan Kim Seong Yeon Kim Seung-O Yang Nam H. Cho | 2012 | Journal of Bone and Mineral Metabolism2012，，： | 1 |
| 10 | High‐Efficiency Perovskite Solar Cells Based on the Black Polymorph of HC(NH2)2PbI3显示文摘 | Jin‐Wook Lee Dong‐Jin Seol An‐Na Cho Nam‐Gyu Park | 2014 | Adv. Mater2014，，29： | 1 |
| 11 | A hierarchical end-of-life decision model for determining the economic levels of remanufacturing and disassembly under environmental regulations显示文摘 | Hyun Bok Lee Nam Wook Cho Yoo Suk Hong | 2010 | Journal of Cleaner Production2010，，13： | 1 |
| 12 | Simulation of dynamics and control of a double-effect LiBr–H 2 O absorption chiller显示文摘 | Younggy Shin Jung Ah Seo Hyun Wook Cho Sang Chul Nam Jin Hee Jeong | 2009 | Applied Thermal Engineering2009，，13： | 1 |
| 13 | Increasing the efficiency of business processes using atheory of constraints 显示文摘 | Rhee Seung-Hyun Cho Nam Wook Bae Hyerim | 2010 | Information Systems Fron-tiers2010，12，4： | 1 |
| 14 | Predictors of no-reflow after percutaneous coronary intervention for culprit lesion with plaque rupture in infarct-related artery in patients with acute myocardial infarction显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | Journal of Cardiology2009，，1： | 1 |
| 15 | Impact of Post-Discharge Statin Withdrawal on Long-Term Outcomes in Patients with Acute Myocardial Infarction显示文摘 | Min Chul Kim Jae Yeong Cho Hae Chang Jeong Ki Hong Lee Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Joo Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Myung Ho Jeong Jeong Gwan Cho Jong Chun Park Ki-Bae Seung Kiyuk Chang Youngkeun Ahn | 2014 | The American Journal of Cardiology2014，，： | 1 |
| 16 | Comparison of peri-procedural platelet inhibition with prasugrel versus adjunctive cilostazol to dual anti-platelet therapy in patients with ST segment elevation myocardial infarction显示文摘 | Keun-Ho Park Myung Ho Jeong Ki Hong Lee Doo Sun Sim Hyun Ju Yoon Nam Sik Yoon Kye Hun Kim Hyung Wook Park Young Joon Hong Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2014 | Journal of Cardiology2014，，2： | 1 |
| 17 | Alteration of cell cycle in cervical tumor associated with human papillomavirus -cyclin dependent kinase inhibitors 显示文摘 | Nam Hoom Cho Young Tae Kim Jae Wook Kim | 2002 | MJ2002，43，6： | 1 |
| 18 | Impact of diabetes mellitus on plaque vulnerability and clinical outcome in patients with acute myocardial infarction with plaque rupture显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jin A. Song Dong Han Kim Ki Hong Lee Futoshi Yamanaka Min Goo Lee Keun Ho Park Doo Sun Sim Sang Hyun Lee Han Gyun Kim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho | 2011 | International Journal of Cardiology2011，，2： | 1 |
| 19 | Different clinical outcomes of acute kidney injury according to acute kidney injury network criteria in patients between ST elevation and non-ST elevation myocardial infarction显示文摘 | Seung Hwan Hwang Myung Ho Jeong Khurshid Ahmed Min Chul Kim Kyung Hoon Cho Min Goo Lee Jum Suk Ko Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Young keun Ahn Jeong Gwan Cho Jong Chun Park Jung C | 2011 | International Journal of Cardiology2011，，1： | 1 |
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