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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 3 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 4 | Natural area visitors' place meaning and place attachment ascribed to a marine setting 显示文摘 | Christopher J W Gerard T K Stephen G S | 2012 | Journal of Environmental Psychology2012，32，4： | 1 |
| 5 | Per fectly Matched Layer as an Absorbing Boundary Condition for the Linearized Euler Equations in Open and Ducted Domains显示文摘 | Christopher K W T Laurent A Prancesco C | 1998 | Journal of Compu- tational Physics1998，144，： | 1 |
| 6 | Dynamics of photoindueed interracial electron transfer and charge transport in dye-sensitized mesoscopic semiconductors显示文摘 | Vetoer K T Bemard W Joel T Christophe B Jacques-E M | 2007 | Chimia2007，61，： | 1 |
| 7 | The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q Y DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L JONES M R SKELTON R L MURRAY J E CHEN C X QIAN W B SHEN J G DU P EUSTICE M TONG E TANG H B LYONS E PAULL R E MICHAEL T P WALL K RICE D W AL- BERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N A- COB R A GUAN P Z BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J K SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X Y BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRI- PATHI S NEUPANE K WEI H R IRIKURA B PAIDI M JIANG N ZHANG W L PRESTING G WINDSOR A NAVAJAS-P?REZ R TORRES M J FELTUS F A PORTER B LI Y J BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J M SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E DEPAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，7190： | 1 |
| 8 | The draft genome of the transgenic tropical fruit tree papaya (Caricapapaya Linnaeus) 显示文摘 | MING R HOU S FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L SALZBERG S L FENG L JONES M R SKELTON R L MURRAY J E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WA1 C M ACKERMAN C M REN Y LIU C WANG J WANG J NA J K SHAKIROV E V HAAS B THIMMAPURAM I NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS- P?REZ R TORRES M J FELTUS FA PORTER B LI Y BURROUGHS A M LUO MC LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E DEPAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 9 | Tailoring enzymes that modify nonribosomal peptides during and aRerchain elongation on NRPS assembly lines显示文摘 | Christopher T W Chen H W Thomas A K | 2001 | Current Opinion inChem fcal Biology2001，5，： | 1 |
| 10 | Mixedfinite element methods and higher order temporalapproximations for variably saturated groundwater flow显示文摘 | MATTHEW W F CHRISTOPHER E K CASS T M | 2003 | Advances in Water Resources2003，26，： | 1 |
| 11 | Genetic markers for improved disease resistance in animals (BPI) 显示文摘 | CHRISTOPHER K T THOMAS J S SHI X W | 2004 | United States Kind Code: Al Patent Application2004，23，： | 1 |
| 12 | Natural area visitors place meaning and place attachment ascribed to a marine setting 显示文摘 | Christopher J W Gerard T K Stephen G S | 2013 | Journal of Environmental Psychology2013，32，4： | 1 |
| 13 | A study of the interactive effects of strain, strain rate and temperature in severe plastic deformation of copper显示文摘 | TRAVIS L B CHRISTOPHER S TEJAS G M JAMES B M YANG G LARRY F A ALEXANDER H K DALE C W KEVIN P T SRINIVASAN C | 2009 | Acta Materialia2009，57，18： | 1 |
| 14 | Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial显示文摘 | Stanislas Pol Reem H Ghalib Vinod K Rustgi Claudia Martorell Greg T Everson Harvey A Tatum Christophe Hézode Joseph K Lim Jean-Pierre Bronowicki Gary A Abrams Norbert Br?u David W Morris Paul J Thuluvath Robert W Reindollar Philip D Yin Ulysses Diva Rober | 2012 | The Lancet Infectious Diseases2012，，9： | 1 |
| 15 | The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions显示文摘 | Kleffmann T Russenberger D Von Zychlinski A Christopher W Sjolander K Gruissem W Baginsky S | 2004 | Curr Biol2004，14，5： | 1 |
| 16 | Microfabricated heavy metal ion sensor显示文摘 | Gregory T A Kovas Christopher W S Samuel P K | 1995 | Sensors and Actuators B1995，23，： | 1 |
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