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| 1 | Analyses on the tectonic thermal evolution and influence factors in the deep-water Qiongdongnan Basin显示文摘To reveal the tectonic thermal evolution and influence factors on the present heat flow distribution, based on 154 heat flow data, the present heat flow distribution features of the main tectonic units are first analyzed in detail, then the tectonic thermal evolution histories of 20 profiles are reestablished crossing the main deep-water sags with a structural, thermal and sedimentary coupled numerical model. On the basis of the present geothermal features, the Qiongdongnan Basin could be divided into three regions: the northern shelf and upper slope region with a heat flow of 50–70 m W/m2, most of the central depression zone of 70–85 m W/m2, and a NE trending high heat flow zone of 85–105 m W/m2 lying in the eastern basin. Numerical modeling shows that during the syn-rift phase, the heat flow increases generally with time, and is higher in basement high area than in its adjacent sags. At the end of the syn-rift phase, the heat flow in the deepwater sags was in a range of 60–85 m W/m2, while in the basement high area, it was in a range of 75–100 m W/m2. During the post-rift phase, the heat flow decreased gradually, and tended to be more uniform in the basement highs and sags. However, an extensive magmatism, which equivalently happened at around 5 Ma, has greatly increased the heat flow values, and the relict heat still contributes about 10–25 m W/m2 to the present surface heat flow in the central depression zone and the southern uplift zone. Further analyses suggested that the present high heat flow in the deep-water Qiongdongnan Basin is a combined result of the thermal anomaly in the upper mantle, highly thinning of the lithosphere, and the recent extensive magmatism. Other secondary factors might have affected the heat flow distribution features in some local regions. These factors include basement and seafloor topography, sediment heat generation, thermal blanketing, local magmatic injecting and hydrothermal activities related to faulting and overpressure. | WANG Zhenfeng SHI Xiaobin YANG Jun HUANG Baojia SUN Zhen WANG Yahui JIANG Haiyan YU Chuanhai YANG Xiaoqiu | 2014 | Acta Oceanologica Sinica2014，33，12： | 22 |
| 2 | Bayesian Reliability Modeling and Assessment Solution for NC Machine Tools under Small-sample Data显示文摘Although Markov chain Monte Carlo(MCMC) algorithms are accurate, many factors may cause instability when they are utilized in reliability analysis; such instability makes these algorithms unsuitable for widespread engineering applications. Thus, a reliability modeling and assessment solution aimed at small-sample data of numerical control(NC) machine tools is proposed on the basis of Bayes theories. An expert-judgment process of fusing multi-source prior information is developed to obtain the Weibull parameters' prior distributions and reduce the subjective bias of usual expert-judgment methods. The grid approximation method is applied to two-parameter Weibull distribution to derive the formulas for the parameters' posterior distributions and solve the calculation difficulty of high-dimensional integration. The method is then applied to the real data of a type of NC machine tool to implement a reliability assessment and obtain the mean time between failures(MTBF). The relative error of the proposed method is 5.8020×10-4 compared with the MTBF obtained by the MCMC algorithm. This result indicates that the proposed method is as accurate as MCMC. The newly developed solution for reliability modeling and assessment of NC machine tools under small-sample data is easy, practical, and highly suitable for widespread application in the engineering field; in addition, the solution does not reduce accuracy. | YANG Zhaojun KAN Yingnan CHEN Fei XU Binbin CHEN Chuanhai YANG Chuangui | 2015 | Chinese Journal of Mechanical Engineering2015，28，6： | 16 |
| 3 | Bottom water temperature measurements in the South China Sea,eastern Indian Ocean and western Pacific Ocean显示文摘文章报道了一批新的海底底水温度(BWT)数据,其中南海(SCS)158个站位、东印度洋(EIO)30个站位及西太平洋(WPO)37个站位。基于这批新的BWT数据,获得南海和西太平洋海域底水温度与水深经验关系,可为地球物理和物理海洋提供准确、可靠的海底温度边界。这将有助于海底油气资源调查与评估。同时,这批实测数据表明:1)水深超过3500m的海域,其底水温度在南海约为2.47℃,比东印度洋(~1.34℃)和西太平洋(~1.60℃)稍微偏高。这与大洋传送带模式所预测的情况比较吻合。该模式认为:低温高盐的海水,从北大西洋格陵兰岛和冰岛附近海域下沉到深层,然后向南流动,再与南极洲周围海域的低温高盐海水一同向北进入印度洋和太平洋。而南海是一个相对比较封闭的热带边缘海,其内部海水与印度洋和菲律宾海交换有限,导致海水温度整体高于印度洋和太平洋。2)台西南盆地水深在2700~3000m的部分站位,其底水温高达约3.00℃,明显高于其周边同水深海域底水温度(平均值约为2.33℃)。这可能是台西南盆地海底水热活动导致的结果。3)在东印度洋和西太平洋水深超过4800m海域,底水温度随着水压增大稍有升高,其升高率分别为10.6mK·MPa^(-1)和12.0mK·MPa^(-1)。这与理论估算的深层底水绝热压力温度梯度范围较为吻合。这也意味着东印度洋和西太平洋深层底水,主要由绝热自压作用导致其温度随着深度的增大而升高。 | YANG Xiaoqiu SHI Xiaobin ZHAO Junfeng YU Chuanhai GAO Hongfang CHEN Aihua LU Yuanzheng CEN Xianrong LIN Weiren ZENG Xin XU Hehua REN Ziqiang ZHOU Shengqi XU Ziying SUN Jinlong KAMIYA Nana LIN Jian | 2018 | 热带海洋学报2018，37，5： | 8 |
| 4 | Isolation and identification of Starmerella davenportii strain Do18 and its application in black tea beverage fermentation显示文摘The objective of this study was to isolate and identify a yeast strain from the kombucha beverage and evaluate its potential as a novel starter in beverage fermentation in vitro.Starmerella davenportii Do18 was characterized for its cholesterol reduction;growth at different conditions such as temperatures(25,30,37 and 42◦C),low pH(1.2,1.5,2.03.0,and 7.0),bile salts(0%,0.25%,0.5%,1%and 2%)high-sucrose stress(2%,10%,20%,40%and 60%);and in-vitro survival in gastric and intestinal environments.Results showed that the yeast strain has a cholesterol-lowering capacity of 45%±2%,grew at temperature of 37◦C and is resistant to pH 1.5,2%bile and 40%sucrose solution,could survive in simulated gastric and intestinal environments.The physicochemical characteristics of the fermented beverages were also evaluated,which indicated that the yeast has pH reduction capacity and can produce organic acids and volatile compound such as 2-phenylethanol.Furthermore,the fermented beverage also has high total phenolics and flavonoids content and showed great antioxidant and antimicrobial activities.Therefore,the findings of this research provide strong evidence that S.davenportii Do18 has good fermentation properties,can be a potential starter in food and beverage fermentation. | Chuanhai Tu Wenxiu Hu Sijie Tang Ling Meng Zhihai Huang Xiao Xu Xiudong Xia Fidelis Azi Mingsheng Dong | 2020 | Food Science and Human Wellness2020，9，4： | 8 |
| 5 | Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly显示文摘Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaphase-anaphase transition.However,the mechanism underlying the key transition from the mitotic spindle to central spindle before anaphase onset remains elusive.Given the prevalence of chromosome instability phenotype in gastric tumorigenesis,we developed a strategy to model context-dependent cell division using a combination of light sheet microscope and 3D gastric organoids.Light sheet microscopic image analyses of 3D organoids showed that CENP-E inhibited cells undergoing aberrant metaphase-anaphase transition and exhibiting chromosome segregation errors during mitosis.Highresolution real-time imaging analyses of 2D cell culture revealed that CENP-E inhibited cells undergoing central spindle splitting and chromosome instability phenotype.Using biotinylated syntelin as an affinity matrix,we found that CENP-E forms a complex with PRC1 in mitotic cells.Chemical inhibition of CENP-E in metaphase by syntelin prevented accurate central spindle assembly by perturbing temporal assembly of PRC1 to the midzone.Thus,CENP-E-mediated PRC1 assembly to the central spindle constitutes a temporal switch to organize dynamic kinetochore microtubules into stable midzone arrays.These findings reveal a previously uncharacterized role of CENP-E in temporal control of central spindle assembly.Since CENP-E is absent from yeast,we reasoned that metazoans evolved an elaborate central spindle organization machinery to ensure accurate sister chromatid segregation during anaphase and cytokinesis. | Xu Liu Leilei Xu Junying Li Phil Y.Yao Wanjuan Wang Hazrat Ismail Haowei Wang Bryce Liao Zhihong Yang Tarsha Ward Ke Ruan Jianchun Zhang Quan Wu Ping He Xia Ding Dongmei Wang Chuanhai Fu Zhen Dou Feng Yan Wenwen Wang Xing Liu Xuebiao Yao | 2020 | Journal of Molecular Cell Biology2020，12，8： | 3 |
| 6 | Health-related quality of life among rural residents aged 45-69 years in Hua County, Henan Province, China: Results of ESECC Trial for esophageal cancer screening with endoscopy显示文摘Objective: There have been few population-based studies evaluating health related quality of life(HRQOL) in rural populations in China, and this study aimed to assess the current status of and risk factors for HRQOL in a general rural population in high risk region of esophageal cancer in China.Methods: From November 2015 to September 2016, 12,085 permanent residents aged 45–69 years from 257 villages in the Endoscopic Screening for Esophageal Cancer in China(ESECC) trial(Clinical Trials.gov:NCT01688908) randomly selected from Hua County, Henan Province, China were interviewed. The EQ-5 D-3 L,a generic measure of HRQOL, and a questionnaire were used to assess their HRQOL and potential risk factors.Results: Among all the participants, 30.62% of the participants reported problems in at least one EQ-5 D dimension. Pain/discomfort(25.52%) was the most frequently reported problem followed by anxiety/depression(7.97%), mobility(5.82%), usual activities(2.61%) and self-care(1%). These rural residents had a mean EQ-5 D index score of 0.948, and lower EQ-5 D index scores were associated with older age, female gender, lower levels of household annual per capita income, living alone, using shallow wells as main source of drinking water, exposure to family members smoking, testiness, unhealthy dietary habits, overweight or obesity, upper gastrointestinal cancer related symptoms and chronic diseases.Conclusions: Rural residents in China have a relatively low quality of life. Health promotion programs in this population should focus on the elderly, especially elderly women and the elderly living alone. Improving basic living circumstances and primary medical care services should be priorities. Results of this study will also serve as the basis for the cost-utility evaluation in our ESECC screening trial. | Hui Wang Yaqi Pan Chuanhai Guo Fenglei Li Ruiping Xu Mengfei Liu Zhen Liu Fangfang Liu Hong Cai Yang Ke Zhonghu He | 2018 | Chinese Journal of Cancer Research2018，30，2： | 3 |
| 7 | Mitotic phosphorylation of PRC1 at Thr470 is required for PRC1 oligomerization and proper central spindle organization显示文摘在细胞分裂期间,染色体分离被和着丝点的锭子微导管的相互作用安排。进在分开的染色单体之间的一支组织中央锭子的 interpolarmicrotubules 的戏剧的改变为胞质分裂的开始和实行被要求。中央锭子组织要求有丝分裂的 kinesins, chromosomal 旅客蛋白质建筑群,和微导管捆绑蛋白质 PRC1。由在 Thr470 和 Thr481 的 Cdc2 的 PRC1 isphosphorylated 在有丝分裂期间。然而,在 Thr470 的功能的关联 ofPRC1 磷酸化留下了逃犯。这里,我们证明 thenon-phosphorylatable 异种 PRC1 (T470A ) 然而并非 phospho-mimicking 异种 PRC1 (T470E ) 的那表情引起中央锭子的异常组织。Immunoprecipitation 实验与野类型的 PRC1 显示那 bothPRC1 (T470A ) 和 PRC1 (T470E ) 突变蛋白质伙伴,建议 Thr470 的 thatphosphorylation 不改变 PRC1 自我协会。另外,在 vitroco 沉积,实验证明 PRC1 绑在独立于 Thr470 的 phosphorylationstate 的微导管。胶化过滤实验建议了 PRC1 的 Thr470 promotesoligomerization 的那磷酸化。给 Thr470 磷酸化的那预防禁止 PRC1oligomerization 试管内并且引起中央锭子体内的一个异常组织的事实,我们建议这 phosphorylation 依赖的 PRC1 oligomerization 保证中央锭子汇编在房间周期发生在适当时间。 | Chuanhai Fu Feng Yan Fang Wu Quan Wu Joseph Whittaker Haiying Hu Renming Hu Xuebiao Yao | 2007 | Cell Research2007，17，5： | 3 |
| 8 | Oral microbiome and risk of malignant esophageal lesions in a high-risk area of China:A nested case-control study显示文摘Objective:We aimed to prospectively evaluate the association of oral microbiome with malignant esophageal lesions and its predictive potential as a biomarker of risk.Methods:We conducted a case-control study nested within a population-based cohort with up to 8 visits of oral swab collection for each subject over an 11-year period in a high-risk area for esophageal cancer in China.The oral microbiome was evaluated with 16 S ribosomal RNA(rRNA)gene sequencing in 428 pre-diagnostic oral specimens from 84 cases with esophageal lesions of severe squamous dysplasia and above(SDA)and 168 matched healthy controls.DESeq analysis was performed to identify taxa of differential abundance.Differential oral species together with subject characteristics were evaluated for their potential in predicting SDA risk by constructing conditional logistic regression models.Results:A total of 125 taxa including 37 named species showed significantly different abundance between SDA cases and controls(all P<0.05&false discovery rate-adjusted Q<0.10).A multivariate logistic model including 11 SDA lesion-related species and family history of esophageal cancer provided an area under the receiver operating characteristic curve(AUC)of 0.89(95%CI,0.84-0.93).Cross-validation and sensitivity analysis,excluding cases diagnosed within 1 year of collection of the baseline specimen and their matched controls,or restriction to screenendoscopic-detected or clinically diagnosed case-control triads,or using only bacterial data measured at the baseline,yielded AUCs>0.84.Conclusions:The oral microbiome may play an etiological and predictive role in esophageal cancer,and it holds promise as a non-invasive early warning biomarker for risk stratification for esophageal cancer screening programs. | Fangfang Liu Mengfei Liu Ying Liu Chuanhai Guo Yunlai Zhou Fenglei Li Ruiping Xu Zhen Liu Qiuju Deng Xiang Li Chaoting Zhang Yaqi Pan Tao Ning Xiao Dong Zhe Hu Huanyu Bao Hong Cai Isabel Dos Santos Silva Zhonghu He Yang Ke | 2020 | Chinese Journal of Cancer Research2020，32，6： | 3 |
| 9 | Fifty years of Quaternary palynology in the Tibetan Plateau显示文摘Quaternary palynology in the Tibetan Plateau(TP)was initiated in the 1960s to meet the needs of economic development in western China.Pollen analysis was conducted for the first time on a 200-m long core of Quaternary lacustrine sediments taken from the main body of the TP in order to study pollen assemblages as well as vegetation and climate changes of glacial(cold)/interglacial(warm)periods.Pollen analysis of alpine snow and ice began at the first scientific expedition to the TP in the 1970s.After the 1980s,a series of international collaborative programs were carried out under Sino-French,Sino-German,Sino-Australian,and Sino-American cooperation,marking the integration of Chinese Quaternary palynology society with the international community.New methods for Quaternary palynology were gradually promoted and applied,changing the vegetational and climatic interpretation of Quaternary palynology from qualitative to quantitative.Since the 1990s,many palynologists have carried out extensive Quaternary palynological studies on fossil pollen sites of more than 60 lakes/sections and alpine glaciers in the TP to discuss the spatiotemporal vegetation changes and climatic and environmental evolution of the TP since the Pleistocene.Over the past half-century,Quaternary palynology in the TP has contributed to the establishment of the Chinese Quaternary pollen database and the study of vegetation and climate evolution since the Last Glacial Maximum(LGM)in the TP.Currently available pollen records revealed the spatial and temporal distribution of vegetation in the TP since the LGM,exhibiting expansions and shrinkages of forest,meadow,grassland and desert in different periods such as the LGM,the last deglaciation,and Holocene optimum period.The paleomonsoon reflected by paleovegetation since the LGM has undergone the changes of weak-strengthening-strong-weakening but still active-shrinking,which is mainly affected by solar insolation. | Lingyu TANG Caiming SHEN Houyuan LU Chuanhai LI Qingfeng MA | 2021 | Science China Earth Sciences2021，64，11： | 3 |
| 10 | Development and validation of a questionnaire-based risk scoring system to identify individuals at high risk for gastric cancer in Chinese populations显示文摘Objective:This study aimed to develop and validate a risk scoring system to identify high-risk individuals carrying malignant lesions in stomach for tailored gastric cancer screening.Methods:A gastric cancer risk scoring system(GC-RSS)was developed based on questionnaire-based predictors for gastric cancer derived from systematic literature review.To assess the capability of this system for discrimination,risk scores for 8,214 and 7,235 outpatient subjects accepting endoscopic examination in two endoscopy centers,and 32,630 participants in a community-based cohort in China were calculated to plot receiver operating characteristic curves and generate area under the curve(AUC).To evaluate the performance of GC-RSS,the screening proportion,sensitivity and detection rate ratio compared to universal screening were used under different risk score cutoff values.Results:GC-RSS comprised nine predictors including advanced age,male gender,low body mass index(<18.5 kg/m^(2)),family history of gastric cancer,cigarette smoking,consumption of alcohol,preference for salty food,irregularity of meals and consumption of preserved food.This tool performed well in determining the risk of malignant gastric lesions with AUCs of 0.763,0.706 and 0.696 in three validation sets.When subjects with risk scores≥5 were evaluated with endoscopy,nearly 50%of these endoscopies could be saved with a detection rate of over 1.5 times achieved.When the cutoff was set at 8,only about 10%of subjects with the highest risk would be offered endoscopy,and detection rates for gastric cancer could be increased 2-4 fold compared to universal screening.Conclusions:An effective questionnaire-based GC-RSS was developed and validated.This tool may play an important role in establishing a tailored screening strategy for gastric cancer in China. | Ren Zhou Hongchen Zheng Mengfei Liu Zhen Liu Chuanhai Guo Hongrui Tian Fangfang Liu Ying Liu Yaqi Pan Huanyu Chen Zhe Hu Hong Cai Zhonghu He Yang Ke | 2021 | Chinese Journal of Cancer Research2021，33，6： | 3 |
| 11 | Identification of cancer patients using claims data from health insurance systems: A real-world comparative study显示文摘Objective: To evaluate the accuracy of identifying cancer patients by use of medical claims data in a health insurance system in China, and provide the basis for establishing the claims-based cancer surveillance system in China.Methods: We chose Hua County, Henan Province as the study site, and randomly selected 300 and 1,200 qualified inpatient electronic medical records(EMRs) as well as the New Rural Cooperative Medical Scheme(NCMS) claims records for cancer patients in Hua County People’s Hospital(HCPH) and Anyang Cancer Hospital(ACH) in 2017. Diagnostic information for NCMS claims was evaluated on an individual level, and sensitivity and positive predictive value(PPV) were calculated taking the EMRs as the gold standard.Results: The sensitivity of NCMS was 95.2%(93.8%-96.3%) and 92.0%(88.3%-94.8%) in ACH and HCPH,respectively. The PPV of the NCMS was 97.8%(96.7%-98.5%) in ACH and 89.0%(84.9%-92.3%) in HCPH.Overall, the weighted and combined sensitivity and PPV of NCMS in Hua County was 93.1% and 92.1%,respectively. Significantly higher sensitivity and PPV in identifying patients with common cancers than noncommon cancers were detected in HCPH and ACH separately(P<0.01).Conclusions: Identification of cancer patients by use of the NCMS is accurate on individual level, and it is therefore feasible to conduct claims-based cancer surveillance in areas not covered by cancer registries in China. | Hongrui Tian Ruiping Xu Fenglei Li Chuanhai Guo Lixin Zhang Zhen Liu Mengfei Liu Yaqi Pan Zhonghu He Yang Ke | 2019 | Chinese Journal of Cancer Research2019，31，4： | 3 |
| 12 | Protein kinase TTK interacts and co-localizes with CENP-E to the kinetochore of human cells显示文摘Spindle checkpoint is an important biochemical signaling cascade during mitosis which monitors the fidelity of chromosome segregation, and is mediated by protein kinases Mpsl and Bubl/BubRl. Our recent studies show that kinesin-related motor protein CENP-E interacts with BubRl and participates in spindle checkpoint signaling. To elucidate the molecular mechanisms underlying spindle checkpoint signaling, we carried out proteomic dissection of human cell kinetochore and revealed protein kinase TTK, human homologue of yeast Mpsl. Our studies show that TTK is localized to the kinetochore of human cells, and interacts with CENP-E, suggesting that TTK may play an important role in chromosome segregation during mitosis. | Jie Zhang Chuanhai Fu Yong Miao Zhen Dou Xuebiao Yao | 2002 | Chinese Science Bulletin2002，47，23： | 3 |
| 13 | Weakness Ranking Method for Subsystems of Heavy-Duty Machine Tools Based on FMECA Information显示文摘Heavy-duty machine tools are composed of many subsystems with different functions,and their reliability is governed by the reliabilities of these subsystems.It is important to rank the weaknesses of subsystems and identify the weakest subsystem to optimize products and improve their reliabilities.However,traditional ranking methods based on failure mode effect and critical analysis(FMECA)does not consider the complex maintenance of products.Herein,a weakness ranking method for the subsystems of heavy-duty machine tools is proposed based on generalized FMECA information.In this method,eight reliability indexes,including maintainability and maintenance cost,are considered in the generalized FMECA information.Subsequently,the cognition best worst method is used to calculate the weight of each screened index,and the weaknesses of the subsystems are ranked using a technique for order preference by similarity to an ideal solution.Finally,based on the failure data collected from certain domestic heavy-duty horizontal lathes,the weakness ranking result of the subsystems is obtained to verify the effectiveness of the proposed method.An improved weakness ranking method that can comprehensively analyze and identify weak subsystems is proposed herein for designing and improving the reliability of complex electromechanical products. | Zhaojun Yang Jinyan Guo Hailong Tian Chuanhai Chen Yongfu Zhu Jia Liu | 2021 | Chinese Journal of Mechanical Engineering2021，34，1： | 2 |
| 14 | Using tandem blades to break loading limit of highly loaded axial compressors显示文摘It is confirmed that tandem-blade configurations have potential to enlarge the flow turning in two-dimension(2D) studies. However, the potential of tandem blades to enlarge the design space for highly loaded axial compressors was rarely investigated in open literatures. The present work aims to show the capability of tandem blades to break the loading limit of conventional blades for highly loaded compressors. The 2D models of the maximum static pressure rise derived in previous work were validated by a large amount experimental data, which showed a good agreement. An E parameter was defined to evaluate the stall margin of compressor based on the theoretical models, which indicated that the tandem blade was able to increase the loading limit of axial compressors. A single-blade stage with a loading coefficient of 0.46(based on the blade tip rotating speed) was designed as the baseline case under the guidance of the E parameter. A tandem-blade stage was then designed by ensuring that the velocity triangles were similar to the single-blade stage. The performances of both stages were investigated experimentally. The results showed that the maximum efficiency of the tandem-blade stage was 92.8%, 1% higher than the single;the stall margin increased from 16.9% to 22.3%. Besides, the maximum pressure rise of tandem rotors was beyond the loading limit of 2D single-blade cascades, which confirmed the potential of tandem blades to break the loading limit of axial compressors. | Baojie LIU Chuanhai ZHANG Guangfeng AN Du FU Xianjun YU | 2022 | Chinese Journal of Aeronautics2022，35，4： | 2 |
| 15 | Responses of winter wheat growth and production under sub-ambient UV-B irradiance显示文摘 | Youfei zheng Wei Gao | 2003 | Proceedings of SPIE2003，4896，： | 1 |
| 16 | The ECME Algorithm显示文摘 | Donald B Rubin | 1994 | A Simple Extension of EM and ECM with Biometrika1994，，81： | 1 |
| 17 | Novel Nanotrees of Crystalline Nickel Formed via Electrolytic Approach显示文摘Tree-shaped nickel nanocrystals with long main trunk and highly ordered branches were prepared via electrolytic method in ethylene glycol solution. The morphology and structures of nanotrees of crystalline nickel can be controlled by the processing of the surfactant(PVP) and electrolytic voltage. Magnetic property measurements at room temperature indicated that the as-prepared nanotrees of crystalline nickel possess higher saturation magnetism(MS) and coercivity(HC) than those of corresponding bulk nickel materials. | Jian Wang Liying Zhang Liangming Wei Chuanhai Jiang Yafei Zhang | 2011 | Nano-Micro Letters2011，3，4： | 1 |
| 18 | The permeability effect of microcystin-RR on Escherichia coli and Bacillus subtilis显示文摘Microcystins are a kind of cyclic hepatoxins produced by many species of cyanobacteria.Most previous work have been done on the toxic effects of microcystins on animals and plants.However,the reports about the effect of microcystins on microbial cells are very limited.In this work,the permeability of MC-RR on the cell outer membrane of Escherichia coli(E.coli) and Bacillus subtilis(B.subtilis) was discussed.The permeability effect of MC-RR on the cell outer membrane of E.coli and B.subtilis under different concentrations was demonstrated by a rapid and sustained reduction in the A675 values of lysozyme-treated cells.The decrease of the absorbance values showed a time-and dose-effect.The extravasations of protein and carbonhydrate increased with the increment of the treated-concentration of MC-RR.The results showed that MC-RR could increase the permeability of cell outer membranes of E.coli and B.subtilis.The synergistic effects of MC-RR and lysozyme on bacteria indicated that MC-RR might play an ecological role in bacteria in combination with other substances in some aquatic environments. | YANG CuiYun XIA ChuanHai ZHOU ShiWei LIU YongDing | 2010 | Chinese Science Bulletin2010，55，18： | 1 |
| 19 | FlexMEMS-enabled hetero-integration for monolithic FBAR-above-IC oscillators显示文摘In this work,a monolithic oscillator chip is heterogeneously integrated by a film bulk acoustic resonator(FBAR)and a complementary metal-oxide-semiconductor(CMOS)chip using FlexMEMS technology.In the 3 D-stacked integrated chip,the thin-film FBAR sits directly over the CMOS chip,between which a 4μm-thick SU-8 layer provides a robust adhesion and acoustic reflection cavity.The proposed system-on-chip(SoC)integration features a simple fabrication process,small size,and excellent performance.The oscillator outputs 2.024 GHz oscillations of-13.79 dB m and exhibits phase noises of-63,-120,and-136 dB c/Hz at 1 kHz,100 kHz,and far-from-carrier offset,respectively.FlexMEMS technology guarantees compact and accurate assembly,process compatibility,and high performance,thereby demonstrating its great potential in SoC hetero-integration applications. | Chuanhai Gao Menglun Zhang Yuan Jiang | 2019 | Nanotechnology and Precision Engineering2019，2，3： | 1 |
| 20 | The effect of chromium dopant on the microstructure and mechanical properties of sputter-deposited copper films 显示文摘 | Wang Xinjian Dong Xianping Jiang Chuanhai | 2009 | Suorace and Coatings Technology2009，20，2021： | 1 |
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