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		题名	作者	年代	出处	被引量
	1	Segregation Analysis of Esophageal Cancer in a Moderately High–Incidence Area of Northern China显示文摘	Weihua Zhang Joan E. Bailey-Wilson Weidong Li Xiuqin Wang Chunlin Zhang Xuezheng Mao Zhihua Liu Chuannong Zhou Min Wu	2000	The American Journal of Human Genetics2000，，1：	1
	2	An ultrastructural study of human bladder cancer treated by photodynamic therapy显示文摘	Chuannong Zhou Bingze Xu Jianguo Xie Yao Yang Zhixia Ding Weizhi Yang Hong Shen Yien Chen Xianwen Ha	1988	Lasers In Medical Science (-)1988，，1：	1
	3	Identification of differentially expressed genes in esophageal cancer through SSH in combination with high throughput reverse Northern screening显示文摘To understand the molecular mechanisms of carcinogenesis of esophagus and to isolate genes with different expression levels in esophageal cancer, suppression sub-tractive hybridization (SSH) was combined with PCR-based cDNA synthesis and reverse Northern on the cancer tissues and matched almost normal mucosa using 5 microgram of total RNA as starting marterial. Eight genes were found expressed differentially in esophageal cancer, in which 5 were known genes and 3 were novel ones; and 6 were down-regulated in cancer tissues, while 2 were up-regulated; 6 were of mid-high abundance and 2 were of low abundance in esophagus. The results revealed that alteration in expression level of multiple genes underlied the initiation and development of esophageal cancer. The differentially expressed genes identified in this study such as liporcotin I, cystatin A, cystatin B, cytokeratin 13 may play roles in dedifferentiation, transformation and malignant proliferation of esophageal cancer. The combination of SSH with	ZHOU Jin LIU Zhihua WANG Xiuqin DING Fang ZHOU Chuannong WU Min	2001	Chinese Science Bulletin2001，46，14：	1
	4	Differential expression analysis of matrix metallo-proteinase 20(MMP20) in human esophageal cancer显示文摘The aim of this study was to investigate the different expressions of MMP20 in the process of esophageal cancer. RT-PCR, immunohistochemistry and Western blot were employed to detect the mRNA expression and protein expression of MMP20. Compared with the corresponding normal esophagus tissues, results showed the common trend of the dramatical overexpression of MMP20 in the esophageal cancer tissues. The analysis of MMP20 expression in different clinical early stages of esophageal cancer by RT-PCR indicated that MMP20 was much more overexpressed in the esophageal cancer with invasion than in the early stages. This suggested that MMP20 might play an important role in the progression of esophageal cancer. It probably plays a critical role in tumor invasion.	YANG Cuihong LIU Zhihua WANG Qun LUO Aiping SUN Yuntian ZHANG Xun WANG Xiuqin ZHOU Chuannong WU Min	2001	Chinese Science Bulletin2001，46，12：	0

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